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Development of coils for transcranial magnetic stimulation at patients' home

Research Project

Project/Area Number 17K20088
Research Category

Grant-in-Aid for Challenging Research (Exploratory)

Allocation TypeMulti-year Fund
Research Field Biomedical engineering and related fields
Research InstitutionThe University of Tokyo

Principal Investigator

Sekino Masaki  東京大学, 大学院工学系研究科(工学部), 准教授 (20401036)

Co-Investigator(Kenkyū-buntansha) 齋藤 洋一  大阪大学, 医学系研究科, 特任教授(常勤) (20252661)
熊田 亜紀子  東京大学, 大学院工学系研究科(工学部), 教授 (20313009)
Project Period (FY) 2017-06-30 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2018: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2017: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywords磁気刺激 / 医療機器 / 生体磁気 / 電気電子 / 生体制御・治療 / 生体情報・計測 / 疼痛
Outline of Final Research Achievements

This study aimed at proposing a double-D coil which expands the area of stimulation in the brain. The results showed that the coil deliverded sufficiently strong electric fields to the target region even when coil had small displacement. While an existing coil loses stimulation effects by a displacement of 5 mm, the double-D coil maintains stimulating effects at 10 mm. In addition, the double-D coil has an inductance comparable to the figure-eight coil. The double-D coil can be positioned using compact and simple equipments.

Academic Significance and Societal Importance of the Research Achievements

脳卒中後遺症や精神疾患などにおいて,薬物治療が奏功しない患者に対して,経頭蓋磁気刺激が効果を発揮する場合があり,薬物治療を補完する治療として期待されている.しかし従来の磁気刺激用コイルでは,コイルを脳内のスイートスポットに精密に位置決めする必要があった.本研究では,新しいコイル(ダブルDコイル)を提案して試作し,数値解析と健常者を対象とした試験によって性能評価を行った.従来のコイルに比べて,位置ずれに強いことが示され,よりコンパクトな機構でコイル位置決めができる可能性を示した.

Report

(3 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • Research Products

    (6 results)

All 2019 2018 2017

All Journal Article (1 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (5 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Electromagnetic and mechanical characterization of a flexible coil for transcranial magnetic stimulation2019

    • Author(s)
      Mengfei Liu, Pauli H. Tuovinen, Yuta Kawasaki, Mohamed Amine Yedeas, Youichi Saitoh, and Masaki Sekino
    • Journal Title

      AIP Advances

      Volume: 9 Issue: 3 Pages: 035335-035335

    • DOI

      10.1063/1.5080148

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] A geometry-variable Tcoil for the medical application of transcranial magnetic stimulation2019

    • Author(s)
      Mengfei Liu, Shuang Liu, Mohamed Amine Yedeas, Yuta Kawasaki, Masaki Sekino
    • Organizer
      URSI Asia Pacific Radio Science Conference
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 在宅経頭蓋磁気刺激治療のための頭部表面形状を考慮した焦点拡大コイルの開発2018

    • Author(s)
      川崎雄太, 細見晃一, 山本啓太, 原伸太郎, 阿部裕輔, 齋藤洋一, 関野正樹
    • Organizer
      電気学会マグネティックス研究会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 頭部形状の個人差の影響を吸収するためのフレキシブルな経頭蓋磁気刺激用コイルの開発2018

    • Author(s)
      劉夢斐, Tuovinen Pauli, 川崎雄太, Yedeas Amine, 関野正樹
    • Organizer
      電気学会マグネティックス研究会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Flexible coil for transcranial magnetic stimulation2017

    • Author(s)
      P. Tuovinen, Y. Kawasaki, and M. Sekino
    • Organizer
      62nd Annual Conference on Magnetism and Magnetic Materials
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] TMSコイル周辺の電界分布測定2017

    • Author(s)
      小林拓人, 熊田亜紀子, 日高邦彦, 関野 正樹
    • Organizer
      放電学会年次大会
    • Related Report
      2017 Research-status Report

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Published: 2017-07-21   Modified: 2020-03-30  

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