Development of a solution for environmental pollution caused by economic globalization

• Project/Area Number: 17KT0033
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Multi-year Fund
• Section: 特設分野
• Research Field: Global Studies
• Research Institution: Nagoya University
• Principal Investigator: Kato Masashi 名古屋大学, 医学系研究科, 教授 (10281073)
• Co-Investigator(Kenkyū-buntansha): 大神 信孝 藤田医科大学, 医学部, 教授 (80424919) ; 矢嶋 伊知朗 芝浦工業大学, システム理工学部, 教授 (80469022) ; 田崎 啓 名古屋大学, 医学系研究科, 講師 (80333326)
• Project Period (FY): 2017-07-18 – 2024-03-31
• Project Status: Completed (Fiscal Year 2023)
• Budget Amount: ¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000); Fiscal Year 2020: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000); Fiscal Year 2019: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000); Fiscal Year 2018: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2017: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
• Keywords: 皮革産業 / 有害元素汚染 / 健康障害 / 浄化材 / 水質汚染 / バングラデシュ / クロム汚染 / 健康影響 / グローバル・イシュー / 皮革工場労働者 / クロム / 皮革工場 / 3価クロム / フェノール / 河川 / 排水路 / 環境モニタリング / 浄化 / 水圏 / 形質変換 / 分子機構 / 皮膚黒色症 / 6価クロム / 環境 / 社会医学 / 癌 / 環境対応 / 環境技術

Outline of Final Research Achievements

The leather products are classified into chrome tanning and others. More than 80% of leather products in the world are produced by chrome tanning because its production cost is low and its import taxe is extremely low. Developed countries are imposing the chrome tanning process that induce the environmental pollution and health disturbances in tannery workers on developing countries with economic globalization, creating a new global issue. This study elucidated the environmental pollution caused by the leather industry and health disturbances among tannery workers in developing countries by a two-way approach to developing and developed countries.

Academic Significance and Societal Importance of the Research Achievements

本研究は、2017-2023年においてハザリバーグと周辺地域の環境調査（フィールド研究）を実施し、クロムをはじめとする種々の有害元素汚染の状況を経時的に解明した。また、皮革工場労働者100名と事務労働者50名（対照）に対する疫学調査を実施し、3価クロムが皮膚障害・聴覚障害・腎障害等を誘発する可能性を解明した。さらに、3価と6価のクロムだけでなく鉛・鉄・マンガン等を高効率に吸着できる吸着材を開発した。以上のように、本研究は、単に皮革産業に起因するグローバル・イシューの現状を解明しただけでなく、解決策を提案したという点を考慮すると、学術的意義・社会的意義は大きい。

Research Products

• [Int'l Joint Research] ダッカ大学/家族保健省(バングラデシュ)
• [Int'l Joint Research] パリ大学/INSERM/Henri Mondor病院(フランス)
• [Int'l Joint Research] Dhaka大学/厚生省(バングラデシュ)
• [Int'l Joint Research] ダッカ大学/バングラデシュ健康・家族福祉省(バングラデシュ)
• [Int'l Joint Research] ダッカ大学/保健省/Sheikh Mujib医科大学(バングラデシュ)
• [Int'l Joint Research] Institut Cochin(フランス)
• [Int'l Joint Research] ダッカ大学/保健省/Sheikh Mujib医科大学(バングラデシュ)
• [Int'l Joint Research] ダッカ大学/保健省/Sheikh Mujib医科大学(バングラデシュ)
• [Int'l Joint Research] Institut Cochin/Cnrs/パリデカルト大学(フランス)
• [Int'l Joint Research] ダッカ大学(バングラデシュ)
• [Journal Article] Beneficial and adverse effects of dam construction in canal tannery wastewater effluent with a high content of chromium in Hazaribagh, Bangladesh (2024)
  • Author(s): Kurniasari Fitri、Htike Maw Than、Tazaki Akira、Kagawa Takumi、Al Hossain M.M. Aeorangajeb、Akhand Anwarul Azim、Ahsan Nazmul、Ohnuma Shoko、Iwasaki Naruhito、Kato Masashi
  • Journal Title: Chemosphere Volume: 350 Pages: 141047-141047
  • DOI: 10.1016/j.chemosphere.2023.141047
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Upregulation of IL4‐induced gene 1 enzyme by B2 cells during melanoma progression impairs their antitumor properties (2024)
  • Author(s): Bekkat F, Seradj M, Lengagne R, Fiore F, Kato M, Lucas B, Castellano F, Molinier-Frenkel V, Richard Y, Prevost-Blondel A
  • Journal Title: European Journal of Immunology Volume: 54 Issue: 4 Pages: 2350615-2350630
  • DOI: 10.1002/eji.202350615
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Unexpected associations of long-term and excessive exposure to trivalent chromium with hypertension and glycosuria in male tannery workers (2023)
  • Author(s): Tsuchiyama Tomoyuki、Chen Dijie、Al Hossain M.M. Aeorangajeb、Tazaki Akira、Kagawa Takumi、Gu Yishuo、Gao Yanjun、Kurniasari Fitri、Ahsan Nazmul、Akhand Anwarul A.、Kato Masashi
  • Journal Title: Chemosphere Volume: 337 Pages: 139190-139190
  • DOI: 10.1016/j.chemosphere.2023.139190
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Efficient removal of molybdate from groundwater with visible color changes using wasted aerobic granular sludge (2023)
  • Author(s): Yuan Tian、Xu Jing、Wang Zhiwei、Lei Zhongfang、Kato Masashi、Shimizu Kazuya、Zhang Zhenya
  • Journal Title: Separation and Purification Technology Volume: 317 Pages: 123849-123849
  • DOI: 10.1016/j.seppur.2023.123849
  • Peer Reviewed / Open Access
• [Journal Article] Elevated arsenic level in fasting serum via ingestion of fish meat increased the risk of hypertension in humans and mice (2023)
  • Author(s): Kagawa Takumi、Ohgami Nobutaka、He Tingchao、Tazaki Akira、Ohnuma Shoko、Naito Hisao、Yajima Ichiro、Chen Dijie、Deng Yuqi、Tamura Takashi、Kondo Takaaki、Wakai Kenji、Kato Masashi
  • Journal Title: European Heart Journal Open Volume: 3 Issue: 5 Pages: 1-12
  • DOI: 10.1093/ehjopen/oead074
  • Peer Reviewed / Open Access
• [Journal Article] Retinal ferroptosis as a critical mechanism for the induction of retinochoroiditis during ocular toxoplasmosis. (2023)
  • Author(s): Yamada K, Tazaki A, Ushio-Watanabe N*, Usui Y, Takeda A, Matsunaga M, Suzumura A, Shimizu H, Zheng H, Ariefta NR, Yamamoto M, Hara H, Goto H, Sonoda K, Nishiguchi KM, Kato M, Nishikawa Y, Toyokuni S, Kaneko H.
  • Journal Title: Redox Biology Volume: 67 Pages: 102890-102890
  • DOI: 10.1016/j.redox.2023.102890
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Actin crosslinking by α-actinin averts viscous dissipation of myosin force transmission in stress fibers (2023)
  • Author(s): Katsuta Hiroki、Okuda Satoru、Nagayama Kazuaki、Machiyama Hiroaki、Kidoaki Satoru、Kato Masashi、Sokabe Masahiro、Miyata Takaki、Hirata Hiroaki
  • Journal Title: iScience Volume: 26 Issue: 3 Pages: 106090-106090
  • DOI: 10.1016/j.isci.2023.106090
  • Peer Reviewed / Open Access
• [Journal Article] Zinc deficiency is associated with the development of ovarian endometrial cysts. (2023)
  • Author(s): Toshimichi Onuma、 Tetsuya Mizutani、 Yuko Fujita、 Nobutaka Ohgami、 Shoko Ohnuma、 Masashi Kato、 Yoshio Yoshida
  • Journal Title: American Journal of Cancer Research Volume: 13(3) Pages: 1049-1066
  • Peer Reviewed
• [Journal Article] Redistribution of potentially toxic elements in the hydrosphere after the relocation of a group of tanneries (2022)
  • Author(s): Kurniasari Fitri、Tazaki Akira、Hashimoto Kazunori、Yuan Tian、Al Hossain M.M. Aeorangajeb、Akhand Anwarul Azim、Ahsan Nazmul、Ohnuma Shoko、Kato Masashi
  • Journal Title: Chemosphere Volume: 303 Pages: 135098-135098
  • DOI: 10.1016/j.chemosphere.2022.135098
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Decreased hearing levels at frequencies for understanding speech in tannery workers exposed to a high level of trivalent chromium in Bangladesh (2022)
  • Author(s): Gu Yishuo、Ohgami Nobutaka、Al Hossain M.M. Aeorangajeb、Tazaki Akira、Tsuchiyama Tomoyuki、He Tingchao、Aoki Masayo、Ahsan Nazmul、Akhand Anwarul Azim、Kato Masashi
  • Journal Title: Chemosphere Volume: 306 Pages: 135571-135571
  • DOI: 10.1016/j.chemosphere.2022.135571
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Potential application of a hydrotalcite-like compound for reduction of toxicity to aquatic organisms via rapid and efficient removal of hydrogen sulfide (2022)
  • Author(s): Yuan Tian、Hashimoto Kazunori、Tazaki Akira、Hasegawa Masahiro、Kurniasari Fitri、Ohta Chihiro、Aoki Masayo、Ohgami Nobutaka、Kato Masashi
  • Journal Title: Journal of Environmental Management Volume: 321 Pages: 115861-115861
  • DOI: 10.1016/j.jenvman.2022.115861
  • Peer Reviewed
• [Journal Article] Vascular endothelium as a target tissue for short-term exposure to low-frequency noise that increases cutaneous blood flow (2022)
  • Author(s): Deng Yuqi、Ohgami Nobutaka、Kagawa Takumi、Kurniasari Fitri、Chen Dijie、Kato Masashi、Tazaki Akira、Aoki Masayo、Katsuta Hiroki、Tong Keming、Gu Yishuo、Kato Masashi
  • Journal Title: Science of The Total Environment Volume: 851 Pages: 158828-158828
  • DOI: 10.1016/j.scitotenv.2022.158828
  • Peer Reviewed
• [Journal Article] Calcitriol inhibits arsenic-promoted tumorigenesis through regulation of arsenic-uptake in a human keratinocyte cell line (2022)
  • Author(s): Ichiro Yajima、 Akira Tazaki、 Nobutaka Ohgami、 Masashi Kato
  • Journal Title: American Journal of Cancer Research Volume: 12(11) Pages: 5019-5028
  • Peer Reviewed
• [Journal Article] Significance of platinum distribution to predict platinum resistance in ovarian cancer after platinum treatment in neoadjuvant chemotherapy (2022)
  • Author(s): Uno Kaname、Yoshikawa Nobuhisa、Tazaki Akira、Ohnuma Shoko、Kitami Kazuhisa、Iyoshi Shohei、Mogi Kazumasa、Yoshihara Masato、Koya Yoshihiro、Sugiyama Mai、Tamauchi Satoshi、Ikeda Yoshiki、Yokoi Akira、Kikkawa Fumitaka、Kato Masashi、Kajiyama Hiroaki
  • Journal Title: Scientific Reports Volume: 12 Issue: 1 Pages: 4513-4513
  • DOI: 10.1038/s41598-022-08503-7
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Impaired phosphorylation of c-Ret causes cerebellar hypoplasia in mice with Hirschsprung disease. (2021)
  • Author(s): Ohgami N, Iizuka A, Hirai H, Yajima I, Iida M, Shimada A, Tsuzuki T, Jijiwa M, Asai N, Takahashi M, Kato M
  • Journal Title: J Biol Chem Volume: - Pages: 100389-100389
  • DOI: 10.1016/j.jbc.2021.100389
  • Peer Reviewed / Open Access
• [Journal Article] Intranasal levels of lead as an exacerbation factor for allergic rhinitis in humans and mice. (2021)
  • Author(s): Xu H, Ohgami N, Sakashita M, Ogi K, Hashimoto K, Tazaki A, Tong K, Aoki M, Fujieda S, Kato M
  • Journal Title: J Allergy Clin Immunol Volume: - Issue: 1 Pages: 139-147.e10
  • DOI: 10.1016/j.jaci.2021.03.019
  • NAID: 120007183197
  • Peer Reviewed
• [Journal Article] Reply (2021)
  • Author(s): Kagawa Takumi、Tazaki Akira、Xu Huadong、Ohgami Nobutaka、Kato Masashi
  • Journal Title: Journal of Allergy and Clinical Immunology Volume: 148 Issue: 2 Pages: 655-656
  • DOI: 10.1016/j.jaci.2021.05.025
  • NAID: 120007192022
  • Peer Reviewed
• [Journal Article] Development of an efficient remediation system with a low cost after identification of water pollutants including phenolic compounds in a tannery built-up area in Bangladesh (2021)
  • Author(s): Yuan Tian、Tazaki Akira、Hashimoto Kazunori、Al Hossain M.M. Aeorangajeb、Kurniasari Fitri、Ohgami Nobutaka、Aoki Masayo、Ahsan Nazmul、Akhand Anwarul Azim、Kato Masashi
  • Journal Title: Chemosphere Volume: 280 Pages: 130959-130959
  • DOI: 10.1016/j.chemosphere.2021.130959
  • NAID: 120007183198
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Increased levels of renal damage biomarkers caused by excess exposure to trivalent chromium in workers in tanneries (2020)
  • Author(s): Tsuchiyama Tomoyuki、Tazaki Akira、Al Hossain MM Aeorangajeb、Yajima Ichiro、Ahsan Nazmul、Akhand Anwarul Azim、Hashimoto Kazunori、Ohgami Nobutaka、Kato Masashi
  • Journal Title: Environmental Research Volume: 188 Pages: 109770-109770
  • DOI: 10.1016/j.envres.2020.109770
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Hair graying with aging in mice carrying oncogenic RET (2020)
  • Author(s): Iida M, Tazaki A, Yajima I, Ohgami N, Taguchi N, Goto Y, Kumasaka YM, Prevost-Blondel A, Kono M, Akiyama M, Takahashi M, Kato M
  • Journal Title: Aging Cell Volume: 19(11) Issue: 11
  • DOI: 10.1111/acel.13273
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Multidisciplinary approach to assess the toxicities of arsenic and barium in drinking water (2020)
  • Author(s): Kato Masashi、Ohgami Nobutaka、Ohnuma Shoko、Hashimoto Kazunori、Tazaki Akira、Xu Huadong、Kondo-Ida Lisa、Yuan Tian、Tsuchiyama Tomoyuki、He Tingchao、Kurniasari Fitri、Gu Yishuo、Chen Wei、Deng Yuqi、Komuro Kanako、Tong Keming、Yajima Ichiro
  • Journal Title: Environmental Health and Preventive Medicine Volume: 25 Issue: 1 Pages: 16-16
  • DOI: 10.1186/s12199-020-00855-8
  • NAID: 210000158248
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A new method with an explant culture of the utricle for assessing the influence of exposure to low frequency noise on the vestibule (2020)
  • Author(s): Ohgami N, He T, Negishi-Oshino R, Gu Y, Li X, Kato M
  • Journal Title: J Toxicol Environ Health, Part A Volume: 83(5) Issue: 5 Pages: 215-218
  • DOI: 10.1080/15287394.2020.1746945
  • NAID: 120006869634
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Peptides containing the MXXCW motif inhibit oncogenic RET kinase activity with a novel mechanism of action. (2020)
  • Author(s): Takeda K, Kawamoto Y, Nagasaki Y, Okuno Y, Goto Y, Iida M, Yajima I, Ohgami N, Kato M
  • Journal Title: Am J Cancer Res Volume: 10（1） Pages: 336-349
  • Peer Reviewed / Open Access
• [Journal Article] Application of a human mesoderm tissue elongation system in vitro derived from human induced pluripotent stem cells to risk assessment for teratogenic chemicals (2020)
  • Author(s): Ninomiya Hiromasa、Intoh Atsushi、Ishimine Hisako、Onuma Yasuko、Ito Yuzuru、Michiue Tatsuo、Tazaki Akira、Kato Masashi
  • Journal Title: Chemosphere Volume: 250 Pages: 126124-126124
  • DOI: 10.1016/j.chemosphere.2020.126124
  • Peer Reviewed / Open Access
• [Journal Article] Peptides containing the MXXCW motif inhibit oncogenic RET kinase activity with a novel mechanism of action. (2020)
  • Author(s): Takeda K, Kawamoto Y, Nagasaki Y, Okuno Y, Goto Y, Iida M, Yajima I, Ohgami N, Kato M
  • Journal Title: Am J Cancer Res Volume: 10 Pages: 336-349
  • Peer Reviewed / Open Access
• [Journal Article] Chromium-mediated hyperpigmentation of skin in male tannery workers in Bangladesh (2019)
  • Author(s): Al Hossain M.M. Aeorangajeb、Yajima Ichiro、Tazaki Akira、Xu Huadong、Saheduzzaman Md、Ohgami Nobutaka、Ahsan Nazmul、Akhand Anwarul Azim、Kato Masashi
  • Journal Title: Chemosphere Volume: 229 Pages: 611-617
  • DOI: 10.1016/j.chemosphere.2019.04.112
  • NAID: 120006718410
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] cVEMP correlated with imbalance in a mouse model of vestibular disorder (2019)
  • Author(s): Negishi-Oshino Reina、Ohgami Nobutaka、He Tingchao、Ohgami Kyoko、Li Xiang、Kato Masashi
  • Journal Title: Environmental Health and Preventive Medicine Volume: 24 Issue: 1 Pages: 39-39
  • DOI: 10.1186/s12199-019-0794-8
  • NAID: 210000156300
  • Peer Reviewed / Open Access
• [Journal Article] Hearing loss in humans drinking tube well water with high levels of iron in arsenic?polluted area (2019)
  • Author(s): He Tingchao、Ohgami Nobutaka、Li Xiang、Yajima Ichiro、Negishi-Oshino Reina、Kato Yoko、Ohgami Kyoko、Xu Huadong、Ahsan Nazmul、Akhand Anwarul Azim、Kato Masashi
  • Journal Title: Scientific Reports Volume: 9 Issue: 1 Pages: 9028-9028
  • DOI: 10.1038/s41598-019-45524-1
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A unique system that can sensitively assess the risk of chemical leukoderma by using murine tail skin (2019)
  • Author(s): Iida Machiko、Tazaki Akira、Deng Yuqi、Chen Wei、Yajima Ichiro、Kondo-Ida Lisa、Hashimoto Kazunori、Ohgami Nobutaka、Kato Masashi
  • Journal Title: Chemosphere Volume: 235 Pages: 713-718
  • DOI: 10.1016/j.chemosphere.2019.06.185
  • NAID: 120006777551
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Histological analysis of the skin of Abca1-deleted mice: A potential model for dry skin (2019)
  • Author(s): Deng Yuqi、Ohgami Nobutaka、Iida Machiko、Tazaki Akira、Intoh Atsushi、Kondo-Ida Lisa、Lu Rui、Tsuzuki Toyonori、Yokoyama Shinji、Kato Masashi
  • Journal Title: Eur J Dermatol Volume: 29 Issue: 5 Pages: 549-551
  • DOI: 10.1684/ejd.2019.3621
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Heat shock protein 70 is a key molecule to rescue imbalance caused by low frequency noise. (2019)
  • Author(s): Negishi-Oshino R, OhgamiN, He T, Li X, Kato M, Kobayashi M, Gu Y, Komuro K, Angelidis CE, Kato M.
  • Journal Title: Arch Toxicol Volume: 93 Pages: 3219-3228
  • NAID: 120006808769
  • Peer Reviewed
• [Journal Article] Adsorption of molybdenum by melanin (2019)
  • Author(s): Chen W, Hashimoto K, Omata Y, Ohgami N, Tazaki A, Deng Y, Kondo-Ida L, Intoh A, Kato M
  • Journal Title: ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE Volume: 24 Issue: 1 Pages: 36-36
  • DOI: 10.1186/s12199-019-0791-y
  • NAID: 210000156053
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Inhibition of mast cell degranulation by melanin. (2019)
  • Author(s): Kawamoto Y, Kondo H, Hasegawa M, Kurimoto C, Ishii Y, Kato C, Botei T, Shinya M, Murate T, Ueno Y, Kawabe M, Goto Y, Yamamoto R, Iida M, Yajima I, Ohgami N, Kato M, Takeda K.
  • Journal Title: Biochem Pharmacol. Volume: 163 Pages: 178-193
  • DOI: 10.1016/j.bcp.2019.02.015
  • Peer Reviewed
• [Journal Article] For making a declaration of countermeasures against the falling birth rate from the Japanese Society for Hygiene: summary of discussion in the working group on academic research strategy against an aging society with low birth rate (2019)
  • Author(s): Nomura Kyoko、Karita Kanae、Araki Atsuko、Nishioka Emiko、Muto Go、Iwai-Shimada Miyuki、Nishikitani Mariko、Inoue Mariko, et al.
  • Journal Title: Environmental Health and Preventive Medicine Volume: 24 Issue: 1 Pages: 14-14
  • DOI: 10.1186/s12199-019-0768-x
  • NAID: 210000130331
  • Peer Reviewed / Open Access
• [Journal Article] A comprehensive study including monitoring, assessment of health effects and development of a remediation method for chromium pollution (2018)
  • Author(s): Yoshinaga M, Ninomiya H, Al Hossain MMA, Sudo M, Akhand AA, Ahsan N, Alim MA, Khalequzzaman M, Iida M, Yajima I, Ohgami N, Kato M.
  • Journal Title: Chemosphere Volume: 201 Pages: 667-75
  • DOI: 10.1016/j.chemosphere.2018.03.026
  • NAID: 120006496424
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Exposure of Mice to 1,2-Dichloropropane Induces CYP450-Dependent Proliferation and Apoptosis of Cholangiocytes. (2018)
  • Author(s): Zong C, Zhang X, Huang C, Chang J, Garner E, Sakurai T, Kato M, Ichihara S, Ichihara G.
  • Journal Title: Toxicol Sci Volume: 162 Issue: 2 Pages: 559-69
  • DOI: 10.1093/toxsci/kfx272
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Manganese in toenails is associated with hearing loss at high frequencies in humans. (2018)
  • Author(s): Ohgami N, Li X, Yajima I, Oshino R, Ohgami K, Kato Y, Ahsan N, Akhand AA, Kato M
  • Journal Title: Biomarkers Volume: 23 Issue: 6 Pages: 533-539
  • DOI: 10.1080/1354750x.2018.1458153
  • NAID: 120006536930
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Arsenic level in toenails is associated with hearing loss in humans. (2018)
  • Author(s): Li X, Ohgami N, Yajima I, Xu H, Iiida M, Ohino R, Ninomiya H, Shen D, Ahsan N, Akhand AA, Kato M
  • Journal Title: PLoS ONE Volume: 13 Issue: 7 Pages: e0198743-e0198743
  • DOI: 10.1371/journal.pone.0198743
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A disadvantageous effect of adsorption of barium by melanin on transforming activity. (2018)
  • Author(s): Omata Y, Yoshinaga M, Yajima I, Ohgami N, Hashimoto K, Higashimura K, Tazaki A, Kato M
  • Journal Title: Chemosphere Volume: 210 Pages: 384-391
  • DOI: 10.1016/j.chemosphere.2018.07.022
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Inflammation drives nitric oxide synthase 2 expression by γδ T cells and affects the balance between melanoma and vitiligo associated melanoma. (2018)
  • Author(s): Douguet L, Bod L, Labarthe L, Lengagne R, Kato M, Couillin I, Prevost-Blondel A
  • Journal Title: OncoImmunology Volume: 7 Issue: 9 Pages: e1484979-e1484979
  • DOI: 10.1080/2162402x.2018.1484979
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Response to the letter to the editor: Metallothionein MT2A A-5G polymorphism and the risk for chronic kidney disease and diabetes. (2018)
  • Author(s): Hattori Y, Naito M, Satoh M, Nakatochi M, Naito H, Kato M, Takagi S, Matsunaga T, Seiki T, Sasakabe T, Suma S, Kawai S, Okada R, Hishida A, Hamajima N, Wakai K.
  • Journal Title: Toxicol Sci Volume: - Pages: kfw205-kfw205
  • DOI: 10.1093/toxsci/kfw205
  • Peer Reviewed
• [Journal Article] Arsenic levels in cutaneous appendicular organs are correlated with digitally evaluated hyperpigmented skin of the forehead but not the sole in Bangladesh residents. (2017)
  • Author(s): Yajima I, Ahsan N, Akhand AA, Al Hossain MA, Yoshinaga M, Ohgami N, Iida M, Oshino R, Naito M, Wakai K, Kato M.
  • Journal Title: Journal of Exposure Science & Environmental Epidemiology Volume: 28 Issue: 1 Pages: 64-68
  • DOI: 10.1038/jes.2016.70
  • NAID: 120006473550
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Arsenic-mediated hyperpigmented skin via NF-kappa B/Endothelin1 signaling in an originally developed hairless mouse model. (2017)
  • Author(s): Yajima I, Kumasaka MY, Iida M, Osino R, Tanihata H, Al Hossain A MM, Ohgami N, Kato M.
  • Journal Title: Arch Toxicol Volume: 91 Issue: 11 Pages: 3507-16
  • DOI: 10.1007/s00204-017-1975-0
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Oral exposure to arsenic causes hearing loss in young people aged 12-29 years and in young mice. (2017)
  • Author(s): Li X, Ohgami N, Omata Y, Yajima I, Iida M, Oshino R, Ohnuma S, Ahsan N, Akhand AA, Kato M.
  • Journal Title: Sci Rep Volume: 7 Issue: 1 Pages: 6844-6844
  • DOI: 10.1038/s41598-017-06096-0
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Manganese-mediated decrease in levels of c-RET and tyrosine hydroxylase expression in vitro. (2017)
  • Author(s): Kumasaka MY, Yajima I, Ohgami N, Ninomiya H, Iida M, Li X, Oshino R, Tanihata H, Yoshinaga M, Kato M.
  • Journal Title: Neurotox Res Volume: 32 Issue: 4 Pages: 661-70
  • DOI: 10.1007/s12640-017-9783-0
  • NAID: 120006367974
  • Peer Reviewed
• [Presentation] 三価クロムに長期間曝露された皮革工場労働者における高血圧と尿糖の調査 (2024)
  • Author(s): Dijie Chen、土山智之、田崎啓、香川匠、M M Aeorangajeb Al Hossain、Nazmul Ahsan、Anwarul A Akhand、加藤昌志
  • Organizer: 第94回 日本衛生学会学術総会
• [Presentation] 魚肉の過剰な摂取がもたらす、血中ヒ素濃度増加と高血圧のリスク (2024)
  • Author(s): 香川匠、大神信孝、He Tingchao、田﨑啓、大沼章子、Dijie Chen、Deng Yuqi、加藤昌志、
  • Organizer: 第94回 日本衛生学会学術総会
• [Presentation] 眼トキソプラズマ症の検査法および治療法の開発 (2024)
  • Author(s): 田﨑啓、山田和久、潮奈々子、加藤昌志、西川義文、豊國伸哉、兼子裕規
  • Organizer: 第94回 日本衛生学会学術総会
• [Presentation] 三価クロムに慢性的に暴露された労働者における高血圧と尿糖の調査 (2023)
  • Author(s): Dijie Chen、加藤 昌志
  • Organizer: 2023年度日本産業衛生学会東海地方会学会
• [Presentation] 慢性的曝露により聴力に影響を及ぼす有害元素の探索 (2023)
  • Author(s): 青木雅代、Shaohang Jing、Dijie Chen、田﨑啓、大神信孝、加藤 昌志
  • Organizer: 第96回日本産業衛生学会
• [Presentation] 硫化水素を高効率で吸着する浄化材の開発 (2023)
  • Author(s): 田﨑啓、原田、橋本和宣、Kurniasari Fitri、青木雅代、大神信孝、加藤昌志
  • Organizer: 第96回日本産業衛生学会
• [Presentation] 硫化水素を高効率で吸着する浄化材の開発 (2023)
  • Author(s): 谷一碩、大神信孝、田﨑啓、加藤昌志
  • Organizer: 第96回日本産業衛生学会
• [Presentation] 疫学研究と実験研究によるクロム曝露による聴力への影響の解析 (2023)
  • Author(s): Yishuo Gu、大神 信孝、田崎 啓、加藤 昌志
  • Organizer: 第93回 日本衛生学会学術総会
• [Presentation] 汚染源（皮なめし工場群）の移転が環境に与える影響 (2023)
  • Author(s): カーニアサリ フィトリ、田崎 啓、加藤 昌志
  • Organizer: 第93回 日本衛生学会学術総会
• [Presentation] 環境水中の硫化水素を高効率で吸着する浄化剤の開発 (2023)
  • Author(s): 田崎 啓、原 田、橋本 和宣、カーニアサリ フィトリ、青木 雅代、大神 信孝、加藤 昌志
  • Organizer: 第93回 日本衛生学会学術総会
• [Presentation] 経口曝露により聴力低下を誘発する元素の探索 (2023)
  • Author(s): 青木 雅代、Jing Shaohang、Chen Dijie、田崎 啓、大神 信孝、加藤 昌志
  • Organizer: 第93回 日本衛生学会学術総会
• [Presentation] クロム曝露による聴力への影響 (2022)
  • Author(s): Yishuo Gu、大神信孝、田崎啓、加藤昌志
  • Organizer: 第33回日本微量元素学会学術集会
• [Presentation] Investigation of tannery-derived water pollution by phenolic compounds and development of potential remediation system (2022)
  • Author(s): Fitri Kurniasari、Tian Yuan、Akira Tazaki、Nobutaka Ohgami、Masashi Kato
  • Organizer: 2022年度日本産業衛生学会東海地方学会
• [Presentation] Development of remediation system for tannery-related water pollution by phenolic compounds in Bangladesh (2022)
  • Author(s): Fitri KURNIASARI、Tian YUAN、田崎啓、大神信孝、加藤昌志
  • Organizer: 第92回日本衛生学会学術総会
• [Presentation] Development of risk assessment system for occupational leukoderma (2021)
  • Author(s): 張藍月、田崎啓、土屋千明、加藤昌志
  • Organizer: 第94回日本産業衛生学会
• [Presentation] 三価クロムに曝露した皮なめし工場労働者における腎障害マーカーの上昇について (2021)
  • Author(s): 土山智之、田崎啓、M.M. Aeorangajeb Al Hossain、矢嶋伊知朗、加藤昌志
  • Organizer: 第94回日本産業衛生学会
• [Presentation] 三価クロムに曝露した皮なめし工場労働者における腎障害マーカーの上昇について (2020)
  • Author(s): 土山智之、田崎啓、M.M. Aeorangajeb Al Hossain、矢嶋伊知朗、加藤昌志
  • Organizer: 2020年度日本産業衛生学会 東海地方会学会
• [Presentation] 皮革工場集積地におけるフェノール類による水質汚染 (2020)
  • Author(s): 原田、橋本和宜、田崎啓、Fitri Kurniasari、大神信孝、加藤昌志
  • Organizer: 第91回日本衛生学会
• [Presentation] 化学物質の白斑リスク評価系の構築 (2020)
  • Author(s): 土屋千明、田崎啓、飯田真智子、加藤昌志
  • Organizer: 第93回日本産業衛生学会
• [Presentation] 新規白斑リスク評価システムの確立 (2020)
  • Author(s): 田崎啓、近藤梨沙、土屋千明、張藍月、加藤昌志
  • Organizer: 第119回日本皮膚科学会総会
• [Presentation] メラニンを介したモリブデン貯蔵機構 (2020)
  • Author(s): 橋本和宜、田﨑啓、大神信孝、加藤昌志
  • Organizer: 第47回日本毒性学会学術年会
• [Presentation] 聴覚に影響を与える新しい環境因子 (2020)
  • Author(s): 加藤昌志
  • Organizer: 日本聴覚医学会 特別講演
  • Invited
• [Presentation] Withコロナ時代にマッチした「非接触型健康増進刺激」を創出するための医工連携研究 (2020)
  • Author(s): 加藤昌志
  • Organizer: 第122回岡山県医用工学研究会
  • Invited
• [Presentation] 飲用井戸水の有害元素を標的とした学際的衛生学研究：衛生学の未来を語るバージョン (2020)
  • Author(s): 加藤昌志
  • Organizer: 日本衛生学会の未来を語る会
  • Invited
• [Presentation] 低周波騒音曝露による平衡感覚障害の実験研究 (2020)
  • Author(s): 小室佳那子、大神信孝、He Tingchao、加藤昌志
  • Organizer: 日本産業衛生学会 東海地方会学会
• [Presentation] 脂質代謝異常と関連する乾皮症の実験研究 (2020)
  • Author(s): 鄧 雨奇、大神 信孝、田崎 啓、加藤 昌志
  • Organizer: 日本産業衛生学会 東海地方会学会
• [Presentation] 低周波騒音曝露による平衡感覚への影響 (2020)
  • Author(s): 大神信孝、橋本和宜、田﨑啓、加藤昌志
  • Organizer: 第47回日本毒性学会学術年会
• [Presentation] 前庭機能に影響する低周波騒音曝露の実験研究 (2020)
  • Author(s): 小室佳那子、大神信孝、He Tingchao、Yuqi Deng、加藤昌志
  • Organizer: 第93回日本産業衛生学会
• [Presentation] 実験研究による脂質代謝異常と関連する乾皮症の解析 (2020)
  • Author(s): 鄧 雨奇、大神 信孝、田崎 啓、加藤 昌志
  • Organizer: 第93回日本産業衛生学会
• [Presentation] Establishment of a risk assessment system for chemical leukoderma (2020)
  • Author(s): 田崎啓、近藤梨沙、土屋千明、張藍月、Delgama Arachchige Sachini Menuka NISHADHI、林秀美、加藤昌志
  • Organizer: 第45回日本研究皮膚科学会
• [Presentation] 低周波騒音曝露による前庭機能への影響 (2020)
  • Author(s): 大神信孝、He Tingchao、Yuqi Deng、橋本和宜、田崎啓、加藤昌志
  • Organizer: 第90回日本衛生学会学術総会
• [Presentation] 脂質代謝異常が関連する乾皮症の実験研究 (2020)
  • Author(s): Yuqi Deng、大神信孝、田崎啓、He Tingchao、橋本和宣、加藤昌志
  • Organizer: 第90回日本衛生学会学術総会
• [Presentation] 非侵襲的生体サンプルに含まれる鉄レベルと聴力の関連 (2020)
  • Author(s): He Tingchao、大神信孝、Yuqi Deng、橋本和宣、田崎啓、加藤昌志
  • Organizer: 第90回日本衛生学会学術総会
• [Presentation] バングラデシュ皮革工場作業員のクロム曝露により誘発された皮膚疾患 (2020)
  • Author(s): 田﨑啓、Al Hossain MM Aeorangajeb、矢嶋伊知朗、大神信孝、加藤昌志
  • Organizer: 第90回日本衛生学会学術総会
• [Presentation] メラニンによるモリブデン動態制御 (2020)
  • Author(s): 陳 偉、橋本 和宜、田崎 啓、大神 信孝、 加藤 昌志
  • Organizer: 第90回日本衛生学会学術総会
• [Presentation] 飲用井戸水の有害元素を標的とした学際的衛生学研究 (2020)
  • Author(s): 加藤昌志
  • Organizer: 第90回日本衛生学会学術総会
  • Invited
• [Presentation] マンガンの飲水曝露による聴覚系への影響 (2019)
  • Author(s): 大神信孝、李香、押野玲奈、加藤昌志
  • Organizer: 第29回日本微量元素学会学術集会
• [Presentation] 生体サンプルのヒ素レベルと聴力異常の関連 (2019)
  • Author(s): 大神信孝、李香、Xu Huadong、Tingchao He、加藤昌志
  • Organizer: 第89回日本衛生学会学術総会
• [Presentation] ヒト人工多機能性幹細胞（iPS細胞）を用いた催奇形性評価系の開発 (2019)
  • Author(s): 二宮裕将、大神信孝、加藤昌志
  • Organizer: 第89回日本衛生学会学術総会
• [Presentation] メラニンによるバリウム貯蔵と制御 (2019)
  • Author(s): 橋本和宜、Wei Chen、小又尉広、加藤昌志
  • Organizer: 第89回日本衛生学会学術総会
• [Presentation] 生体サンプル中の鉄レベルと聴力異常の相関解析 (2019)
  • Author(s): Tingchao He、大神信孝、李香、Xu Huadong、加藤昌志
  • Organizer: 第89回日本衛生学会学術総会
• [Presentation] Comprehensive environmental study for arsenic-polluted well drinking water. (2018)
  • Author(s): Masashi KATO, Ichiro YAJIMA, Kazunori HASHIMOTO, Xiang LI, Nobutaka OHGAMI
  • Organizer: 5th International Arsenic Symposium in Miyazaki
  • Int'l Joint Research / Invited
• [Presentation] 実験研究と疫学研究によるヒ素曝露の難聴リスクの解析 (2018)
  • Author(s): 李香、大神信孝、押野玲奈、加藤昌志
  • Organizer: 第29回日本微量元素学会学術集会
• [Presentation] ヒトのツメに蓄積するマンガンレベルと聴力の関連 (2018)
  • Author(s): Tingchao He、大神信孝、李香、加藤昌志
  • Organizer: 第29回日本微量元素学会学術集会
• [Presentation] アフガニスタンの飲用井戸水に含まれるウランに対する浄化技術の開発 (2018)
  • Author(s): 須藤誠、モハマド・ダウド・アジミ、サイード・ハフィズラー・ファヤズ、 矢嶋伊知朗、大神信孝、加藤昌志
  • Organizer: 第88回日本衛生学会学術総会
• [Presentation] ヒ素誘導性黒皮症モデルマウスの樹立とその解析 (2018)
  • Author(s): 高木満里絵、矢嶋伊知朗、加藤昌志
  • Organizer: 第88回日本衛生学会学術総会
• [Presentation] ヒトのツメに蓄積するマンガンレベルと聴力の関連 (2018)
  • Author(s): 大神信孝、李香、押野玲奈、矢嶋伊知朗、加藤昌志
  • Organizer: 第88回日本衛生学会学術総会
• [Presentation] ヒ素による癌悪性化メカニズムの解明 (2018)
  • Author(s): 橋本和宜、矢嶋伊知朗、大神信孝、加藤昌志、辻良明
  • Organizer: 第88回日本衛生学会学術総会
• [Presentation] モデルマウスを用いたヒ素誘導性黒皮症の発症機構解析 (2018)
  • Author(s): 矢嶋伊知朗、加藤昌志
  • Organizer: 第17回分子予防環境医学研究会
• [Presentation] ヒ素刺激下における原がん遺伝子CREBの新規活性化機構 (2018)
  • Author(s): 橋本和宜、矢嶋伊知朗、大神信孝、加藤昌志、辻良明
  • Organizer: 第17回分子予防環境医学研究会
• [Presentation] 環境因子により誘発される疾患としてのアレルギー・癌・難聴 (2017)
  • Author(s): 加藤 昌志
  • Organizer: 第48回 日本職業・環境アレルギー学会
  • Invited
• [Presentation] マンガンの飲水投与による難聴の解析 (2017)
  • Author(s): 大神信孝、李香、押野玲奈、加藤昌志
  • Organizer: 第40回 日本神経科学大会
• [Presentation] マンガンの飲水曝露による聴覚系への影響 (2017)
  • Author(s): 大神信孝、李香、押野 玲奈、加藤昌志
  • Organizer: フォーラム2017 衛生薬学・環境トキシコロジー
• [Book] 今日の治療指針 2022年版 (2022)
  • Author(s): 加藤昌志
  • Total Pages: 2224
  • Publisher: 医学書院
  • ISBN: 9784260047760
• [Book] 最先端ナノライフシステム研究 (2022)
  • Author(s): 加藤昌志
  • Total Pages: 221
  • Publisher: 丸善プラネット株式会社
• [Book] 内藤財団時報 (2021)
  • Author(s): 加藤 昌志
  • Total Pages: 83
  • Publisher: 公益財団法人 内藤記念科学振興財団
• [Book] 発酵美容成分の開発 第1章（総論）皮膚色素異常のモデル動物とリスク評価 (2020)
  • Author(s): 田崎啓、飯田真智子、加藤昌志
  • Total Pages: 197
  • Publisher: シーエムシー出版
  • ISBN: 9784781314990
• [Book] Plasma medical Innovation of cancer Therapy: Melanoma. Subchapter 5.8 in Plasma Medical Science (2018)
  • Author(s): Iida M, Omata Y, Yajima I, Sato A, Kajiwara T, Tasaka R, Hori M, Kato M
  • Total Pages: 458
  • Publisher: Elsevier
  • ISBN: 9780128150054
• [Book] NEW予防医学・公衆衛生学 第3章 産業衛生 (2018)
  • Author(s): 加藤昌志
  • Total Pages: 434
  • Publisher: 南江堂
  • ISBN: 9784524251162
• [Remarks] 名古屋大学大学院医学系研究科
  • URL: https://www.med.nagoya-u.ac.jp/medical_J/laboratory/basic-med/social-science/environmental-health/
• [Remarks] 名古屋大学大学院医学系研究科 環境労働衛生学（独自のHP）
  • URL: http://www.med.nagoya-u.ac.jp/hygiene/eindex.html
• [Remarks] 名古屋大学からのプレスリリース
  • URL: https://www.nagoya-u.ac.jp/researchinfo/result/2023/07/post-531.html
• [Remarks] 名古屋大学大学院医学系研究科環境労働衛生学
  • URL: http://www.med.nagoya-u.ac.jp/hygiene/
• [Remarks] 名古屋大学大学院医学系研究科社会生命科学環境労働衛生学（衛生学）
  • URL: https://www.med.nagoya-u.ac.jp/medical_J/laboratory/basic-med/social-science/environmental-health/
• [Remarks] 名古屋大学大学院医学系研究科のホームページ
  • URL: https://www.med.nagoya-u.ac.jp/medical_E/laboratory/basic-med/social-science/environmental-health/
• [Remarks] 名古屋大学大学院医学系研究科環境労働衛生学のホームページ
  • URL: https://www.med.nagoya-u.ac.jp/hygiene/
• [Remarks] 名古屋大学大学院医学系研究科環境労働衛生学のホームページ
  • URL: https://www.med.nagoya-u.ac.jp/hygiene/eindex.html
• [Remarks] 名古屋大学大学院医学系研究科 研究室紹介ホームページ
  • URL: https://www.med.nagoya-u.ac.jp/medical_J/laboratory/basic-med/social-science/environmental-health/
• [Remarks] 環境労働衛生学 独自ホームページ
  • URL: https://www.med.nagoya-u.ac.jp/hygiene/
• [Patent(Industrial Property Rights)] 固化体及びそれを用いた元素吸着材 (2019)
  • Inventor(s): 加藤昌志、橋本和宣
  • Industrial Property Rights Holder: 名古屋大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2019-221966
  • Filing Date: 2019
• [Patent(Industrial Property Rights)] ドクター食器 (2018)
  • Inventor(s): 加藤昌志
  • Industrial Property Rights Holder: 名古屋大学
  • Industrial Property Rights Type: 意匠
  • Filing Date: 2018
  • Acquisition Date: 2019
• [Patent(Industrial Property Rights)] 固化体及びそれを用いた元素吸着材 (2018)
  • Inventor(s): 加藤昌志、橋本和宣
  • Industrial Property Rights Holder: 名古屋大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2018-230662
  • Filing Date: 2018
• [Patent(Industrial Property Rights)] ドクター食器 (2018)
  • Inventor(s): 加藤昌志
  • Industrial Property Rights Holder: 名古屋大学
  • Industrial Property Rights Type: 意匠
  • Filing Date: 2018