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The Mechanism of Intracellular Transport and Kinesin Motors, KIFs : Structure, Function, Dynamics and Regulation

Research Project

Project/Area Number 18002013
Research Category

Grant-in-Aid for Specially Promoted Research

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionThe University of Tokyo

Principal Investigator

HIROKAWA Nobutaka  The University of Tokyo, 大学院・医学系研究科, 特任教授 (20010085)

Co-Investigator(Kenkyū-buntansha) 中田 隆夫  東京大学, 大学院・医学系研究科, 准教授 (50218004)
金井 克光  東京大学, 大学院・医学系研究科, 准教授 (80214427)
野田 泰子  東京大学, 大学院・医学系研究科, 講師 (50262019)
武井 陽介  東京大学, 大学院・医学系研究科, 准教授 (20272487)
岡田 康志  東京大学, 大学院・医学系研究科, 助手 (50272430)
Co-Investigator(Renkei-kenkyūsha) NAKATA Takao  東京大学, 大学院・医学系研究科, 准教授 (50218004)
NODA Yasuko  東京大学, 大学院・医学系研究科, 講師 (50262019)
Research Collaborator KANAI Yoshimitsu  東京大学, 大学院・医学系研究科, 准教授 (80214427)
TAKEI Yosuke  東京大学, 大学院・医学系研究科, 准教授 (20272487)
OKADA Yasushi  東京大学, 大学院・医学系研究科, 助手 (50272430)
TANAKA Yosuke  東京大学, 大学院・医学系研究科, 助手 (90302661)
NITTA Ryo  東京大学, 大学院・医学系研究科, 助教 (40345038)
HOMMA Noriko  東京大学, 大学院・医学系研究科, 助教 (50345039)
MIKI Harukata  東京大学, 大学院・医学系研究科, 助教 (10361461)
OGAWA Tadayuki  東京大学, 大学院・医学系研究科, 特任助教 (40436572)
YAJIMA Hiroaki  東京大学, 大学院・医学系研究科, 特任研究員 (30376412)
Project Period (FY) 2006 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥1,942,980,000 (Direct Cost: ¥1,494,600,000、Indirect Cost: ¥448,380,000)
Fiscal Year 2010: ¥357,110,000 (Direct Cost: ¥274,700,000、Indirect Cost: ¥82,410,000)
Fiscal Year 2009: ¥379,730,000 (Direct Cost: ¥292,100,000、Indirect Cost: ¥87,630,000)
Fiscal Year 2008: ¥397,930,000 (Direct Cost: ¥306,100,000、Indirect Cost: ¥91,830,000)
Fiscal Year 2007: ¥403,520,000 (Direct Cost: ¥310,400,000、Indirect Cost: ¥93,120,000)
Fiscal Year 2006: ¥404,690,000 (Direct Cost: ¥311,300,000、Indirect Cost: ¥93,390,000)
Keywords分子モーター / キネシン / 細胞内輸送 / 微小管 / モーター蛋白 / 細胞内物質輸送 / 分子細胞生物学 / 分子遺伝学 / 構造生物学
Research Abstract

Intracellular transport is fundamental for cellular functions in cells in general. We studied this mechanism focusing on the kinesin superfamily proteins (KIFs). The primary structures of 13 new KIFs were solved. Using molecular cell biology and molecular genetics we revealed that KIF4 is a key molecule determining activity dependent survival or death of juvenile neurons, that KIF26A is fundamental for development of enteric nervous system by acting as a suppressor for GDNF/Ret signaling, and that KIF17 plays a significant role by not only transporting NDMA receptors, but also controlling transcription and translation of NR2B and KIF17 through CREB phosphorylation and ubiquitin-proteasome dependent degradation of NR2A. We solved atomic structures during Mg^<++> and water release from Mg^<++>ADP so that we solved almost all states during ATP hydrolysis which gives us strong bases to understand how KIFs move along microtubules.

Report

(10 results)
  • 2016 Abstract(Follow-up Assessment) ( PDF )   Self-evaluation (Follow-up Assessment) ( PDF )   Comments (Follow-up Assessment) ( PDF )
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report   Self-evaluation Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (141 results)

All 2011 2010 2009 2008 2007 2006 Other

All Journal Article (46 results) (of which Peer Reviewed: 27 results) Presentation (84 results) Book (5 results) Remarks (6 results)

  • [Journal Article] Preferential binding of a kinesin-1 motor to GTP-tubulin-rich microtubules underlies polarized vesicle transport.2011

    • Author(s)
      Nakata, T., et al.
    • Journal Title

      J Cell Biol (掲載確定(印刷中))

    • Related Report
      2010 Final Research Report
  • [Journal Article] Molecular motor KIF17 is fundamental for memory and learning via differential support of synaptic NR2A/2B levels.2011

    • Author(s)
      Yin, X., Y.Takei, M.A.Kido, N.Hirokawa.
    • Journal Title

      Neuron 70

      Pages: 310-325

    • Related Report
      2010 Final Research Report
  • [Journal Article] KIF16B/Rab14 molecular motor complex is critical for early embryonic development by transporting FGF receptor.2011

    • Author(s)
      Ueno, H., X.Huang, Y.Tanaka, N.Hirokawa.
    • Journal Title

      Develop Cell 20

      Pages: 60-71

    • Related Report
      2010 Final Research Report
  • [Journal Article] Molecular motor KIF17 is fundamental for memory and learning via differential support of synaptic NR2A/2B levels.2011

    • Author(s)
      Yin, X., Y.Takei, M.A.Kido, N.Hirokawa.
    • Journal Title

      Neuron

      Volume: (掲載確定(印刷中))

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular motors in neurons : Transport mechanisms and roles in brain function, development, and disease.2010

    • Author(s)
      Hirokawa, N., S.Niwa, Y.Tanaka.
    • Journal Title

      Neuron 68

      Pages: 610-638

    • Related Report
      2010 Final Research Report
  • [Journal Article] Kinesin-1 Hsc/70-dependent mechanism of slow axonal and its relation to fast axonal transport.2010

    • Author(s)
      Terada, S., M.Kinjo, M.Aihara, Y.Takei, N.Hirokawa.
    • Journal Title

      EMBO J 29

      Pages: 843-854

    • Related Report
      2010 Final Research Report
  • [Journal Article] Kinesin-1 Hsc/70-dependent mechanism of slow axonal and its relation to fast axonal transport.2010

    • Author(s)
      Terada, S., M.Kinjo, M.Aihara, Y.Takei, N.Hirokawa.
    • Journal Title

      The EMBO Journal

      Volume: 29 Pages: 843-854

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular motors in neurons : Transport mechanisms and roles in brain function, development, and disease.2010

    • Author(s)
      Hirokawa, N., S.Niwa, Y.Tanaka.
    • Journal Title

      Neuron

      Volume: 68 Pages: 610-638

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] KIF16B/Rab14 molecular motor complex is critical for early embryonic development by transporting FGF receptor.2010

    • Author(s)
      Ueno, H., X.Huang, Y.Tanaka, N.Hirokawa.
    • Journal Title

      Developmental Cell

      Volume: 20 Pages: 60-71

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Kinesin-1 Hsc/70-dependent mechanism of slow axonal and its relation to fast axonal transport2010

    • Author(s)
      Terada, S., M.Kinjo, M.Aihara, Y.Takei, N.Hirokawa
    • Journal Title

      The EMBO Journal 29

      Pages: 843-854

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Observation of Nodal Cilia Movement and Measurement of Nodal Flow.2009

    • Author(s)
      Okada, Y., N.Hirokawa.
    • Journal Title

      Method Cell Biol(ed. by S.M.King, G.J.Pazour, Academic Press. Elsevier Inc.) 91

      Pages: 265-285

    • Related Report
      2010 Final Research Report
  • [Journal Article] The mechanisms of kinesin motor motility : lessons from the monomeric motor KIF1A.2009

    • Author(s)
      Hirokawa, N., R.Nitta, Y.Okada.
    • Journal Title

      Nat Rev Mol Cell Biol 10

      Pages: 877-884

    • Related Report
      2010 Final Research Report
  • [Journal Article] KIF26A is an unconventional kinesin and regulates GDNF-Ret signaling in enteric neuronal development.2009

    • Author(s)
      Zhou R., S.Niwa, N.Homma, Y.Takei, N.Hirokawa.
    • Journal Title

      Cell 139

      Pages: 802-813

    • Related Report
      2010 Final Research Report
  • [Journal Article] Kinesin superfamily motor proteins and intracellular transport.2009

    • Author(s)
      Hirokawa, N., Y.Noda, Y.Tanaka, S.Niwa.
    • Journal Title

      Nat Rev Mol Cell Biol 10

      Pages: 682-696

    • Related Report
      2010 Final Research Report
  • [Journal Article] Fluid dynamic mechanism responsible for breaking the left-right symmetry of the human body : The nodal flow.2009

    • Author(s)
      Hirokawa, N., Y.Okada, Y.Tanaka.
    • Journal Title

      Ann Rev Fluid Mechanics. 41

      Pages: 53-72

    • Related Report
      2010 Final Research Report
  • [Journal Article] Fluid dynamic mechanism responsible for breaking the left-right symmetry of the human body : The nodal flow2009

    • Author(s)
      Hirokawa, N., Y.Okada, Y.Tanaka
    • Journal Title

      Annual Review of Fluid Mechanics 41

      Pages: 53-72

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Kinesin superfamily motor proteins and intracellular transport2009

    • Author(s)
      Hirokawa, N., Y.Noda, Y.Tanaka, S.Niwa
    • Journal Title

      Nature Reviews Molecular Cell Biology 10

      Pages: 682-696

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Left-Right determination : Involvement of molecular motor KIF3, cilia, and nodal flow2009

    • Author(s)
      Hirokawa, N., Y.Tanaka, Y.Okada
    • Journal Title

      Cold Spring Harber Perspectives in Biology 1

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] KIF26A is an unconventional kinesin and regulates GDNF-Ret signaling in enteric neuronal development2009

    • Author(s)
      Zhou R., S.Niwa, N.Homma, Y.Takei, N.Hirokawa
    • Journal Title

      Cell 139

      Pages: 802-813

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The mechanisms of kinesin motor motility : lessons from the monomeric motor KIF1A2009

    • Author(s)
      Hirokawa, N., R.Nitta, Y.Okada
    • Journal Title

      Nature Reviews Molecular Cell Biology 10

      Pages: 877-884

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fluid dynamic mechanism responsible for breaking the left-right symmetry of the human body : The nodal flow2009

    • Author(s)
      Hirokawa, N., Y. Okada and Y. Tanaka
    • Journal Title

      Annual Review of Fluid Mechanics 41

      Pages: 53-72

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Kinesin superfamily motor proteins and intracellular transport2009

    • Author(s)
      Hirokawa, N., Y. Noda, Y. Tanaka, and S. Niwa
    • Journal Title

      Nature Review Molecular Cell Biology (in press)(掲載確定)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The mechanism of motility of Kinesin motors : Lessons from monomeric motor KIF1A2009

    • Author(s)
      Hirokawa, N., R. Nitta, R., and Y. Okada
    • Journal Title

      Nature Review Molecular Cell Biology (in press)(掲載確定)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD.2008

    • Author(s)
      Niwa, S., Y.Tanaka, N.Hirokawa.
    • Journal Title

      Nat Cell Biol 11

      Pages: 1269-1276

    • Related Report
      2010 Final Research Report
  • [Journal Article] Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin.2008

    • Author(s)
      Nitta, R., Y.Okada, N.Hirokawa.
    • Journal Title

      Nat Struct & Mol Biol 15(10)

      Pages: 1067-1075

    • Related Report
      2010 Final Research Report
  • [Journal Article] Intracellular transport and kinesin superfamily proteins, KIFs : structure, function, and dynamics.2008

    • Author(s)
      Hirokawa, N., Y.Noda.
    • Journal Title

      Physiol Revi 88

      Pages: 1089-1118

    • Related Report
      2010 Final Research Report
  • [Journal Article] Disruption of KIF17-Mint1 interation by CamKII-dependent phosphorylation : a molecular model of kinesin-cargo release.2008

    • Author(s)
      Guilaud, L., R.Wong, N.Hirokawa.
    • Journal Title

      Nat Cell Biol 10

      Pages: 19-29

    • Related Report
      2010 Final Research Report
  • [Journal Article] KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD2008

    • Author(s)
      Niwa, S., Y. Tanaka and N. Hirokawa
    • Journal Title

      Nature Cell Biology 11

      Pages: 1270-1276

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin2008

    • Author(s)
      Nitta, R., Y. Okada and N. Hirokawa
    • Journal Title

      Nature Structural & Molecular Biology 15

      Pages: 1067-1075

    • Related Report
      2008 Annual Research Report 2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Intracellular transport and kinesin superfamily proteins, KIFs: structure, function, and dynamics2008

    • Author(s)
      Hirokawa, N. and Y. Noda
    • Journal Title

      Physiological Reviews 88

      Pages: 1089-1118

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Disruption of KIF17-Mint1 interation by CamKII-dependent phosphorylation: a molecular model of kinesin-cargo release2008

    • Author(s)
      Guilaud, L., R. Wong and N. Hirokawa
    • Journal Title

      Nature Cell Biology 10

      Pages: 19-29

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Disruption of KIF17-Mintl interation by CamKII-dependent phosphorylation : amolecular model of kinesin-cargo release2008

    • Author(s)
      Guilaud, L., R. Wong and N. Hirokawa
    • Journal Title

      Nature Cell Biology 10

      Pages: 19-29

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Intracellular transport and kinesin superfamily proteins, KIFs : structure, function, and dynamics2008

    • Author(s)
      Hirokawa, N. and Y. Noda
    • Journal Title

      Physiological Reviews 88

      Pages: 1089-1118

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] KIF1Bbeta-and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD2008

    • Author(s)
      Niwa, S., Y. Tanaka and N. Hirokawa
    • Journal Title

      Nature Cell Biology 11

      Pages: 1270-1276

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Disruption of KIF17-Mintl interation by CamKII-dependent phosphorylation: a molecular model of kinesin-cargo release.2008

    • Author(s)
      Guillaud, L., R. Wong and N. Hirokawa
    • Journal Title

      Nature Cell Biology 10

      Pages: 19-29

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neuronal Polarity and the Kinesin Superfamily Proteins.2007

    • Author(s)
      Nakata, T, N.Hirokawa.
    • Journal Title

      Science STKE

      Pages: 6-6

    • Related Report
      2010 Final Research Report
  • [Journal Article] Neuronal Polarity and the Kinesin Superfamily Proteins.2007

    • Author(s)
      Nakata, T and N. Hirokawa
    • Journal Title

      Science STKE

      Pages: 63-63

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Three-dimensional structures of the flagellar dynein-microtubule complex by cryoelectron microscopy.2007

    • Author(s)
      Oda, T., N. Hirokawa., and M. Kikkawa
    • Journal Title

      Journal of Cell Biology 177

      Pages: 243-252

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations.2006

    • Author(s)
      Kikkawa, M., N.Hirokawa.
    • Journal Title

      EMBO J 25

      Pages: 4187-4194

    • Related Report
      2010 Final Research Report
  • [Journal Article] mRNA Transport in Dendrites : RNA Granules, Motors, and Tracks.2006

    • Author(s)
      Hirokawa, N.
    • Journal Title

      J Neurosci 26

      Pages: 7139-7142

    • Related Report
      2010 Final Research Report
  • [Journal Article] KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.2006

    • Author(s)
      Midorikawa R., Y.Takei, N.Hirokawa.
    • Journal Title

      Cell 125

      Pages: 371-383

    • Related Report
      2010 Final Research Report
  • [Journal Article] Nodal flow and the generation of left-right asymmetry.2006

    • Author(s)
      Hirokawa, N., Y.Tanaka, Y.Okada, S.Takeda.
    • Journal Title

      Cell 125(1)

      Pages: 33-45

    • Related Report
      2010 Final Research Report
  • [Journal Article] KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity2006

    • Author(s)
      Midorikawa R., Y. Takei, and N. Hirokawa
    • Journal Title

      Cell 125

      Pages: 371-383

    • Related Report
      2008 Self-evaluation Report 2006 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nodal flow and the generation of left-right asymmetry2006

    • Author(s)
      Hirokawa, N., Y. Tanaka, Y. Okada and S. Takeda
    • Journal Title

      Cell 125

      Pages: 33-45

    • Related Report
      2008 Self-evaluation Report 2006 Annual Research Report
    • Peer Reviewed
  • [Journal Article] mRNA Transport in Dendrites: RNA Granules, Motors,and Tracks2006

    • Author(s)
      Hirokawa, N
    • Journal Title

      Journal of Neuroscience 26

      Pages: 7139-7142

    • Related Report
      2006 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations2006

    • Author(s)
      Kikkawa, M. and N, Hirokawa
    • Journal Title

      EMBO Journal 25

      Pages: 4187-4194

    • Related Report
      2006 Annual Research Report
    • Peer Reviewed
  • [Presentation] KIF16B/Rab14複合体はFGFレセプターを輸送し初期発生に必須である2011

    • Author(s)
      田中庸介
    • Organizer
      第88回日本生理学会大会/第116回日本解剖学会総会・全国学術集会合同大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2011-03-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] Molecular Motor KIF17Is Fundamental for Memory and Learning via Differential Support of Synaptic NR2A/2B Levels.2011

    • Author(s)
      Yin xiling
    • Organizer
      第88回日本生理学会大会/第116回日本解剖学会総会・全国学術集会合同大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2011-03-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] Intracellular transport and kinesin superfamily molecular motors (KIFs) : Key regulators for neuronal function, development and tumorigenesis.2011

    • Author(s)
      N.Hirokawa.
    • Organizer
      40^<th> Annaul Meeting of the AADR/35^<th> Annual Meeting of the CADR.
    • Place of Presentation
      San Diego, California, USA.
    • Year and Date
      2011-03-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 生命の要、"分子モーター"と細胞内輸送:神経機能、発生、そして腫瘍の制御2011

    • Author(s)
      廣川信隆
    • Organizer
      第23回気道病態研究会
    • Place of Presentation
      東京ステーションコンファレンス6階(東京都)
    • Year and Date
      2011-03-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] Intracellular transport and kinesin superfamily molecular motors (KIFs) : Key regulators for neuronal function, development and tumorigenesis.2011

    • Author(s)
      N.Hirokawa.
    • Organizer
      (Plenary Lecture) 6^<th> International APOCB Congress for Cell Biology.
    • Place of Presentation
      Shangri-La, Manila, Philippines.
    • Year and Date
      2011-02-04
    • Related Report
      2010 Final Research Report
  • [Presentation] Intracellular transport and kinesin superfamily molecular motors (KIFs) : Key regulators for neuronal function, development and tumorigenesis.2011

    • Author(s)
      N.Hirokawa.
    • Organizer
      6^<th> International APOCB Congress for Cell Biology.
    • Place of Presentation
      EDSA Shangri-La, Manila, Philippines.
    • Year and Date
      2011-02-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] The intracellular transport & kinesin superfamily motors, KIFs : Regulation of brain function & development.2011

    • Author(s)
      N.Hirokawa.
    • Organizer
      IMB (Institute of Molecular Biology, Taipei) Symposium 2011
    • Place of Presentation
      IMB B1 Auditorium. Taipei.
    • Year and Date
      2011-01-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] Molecular motor KIF16B is essential for initial germ layer development of embryos.2010

    • Author(s)
      田中庸介
    • Organizer
      第50回米国細胞生物学会
    • Place of Presentation
      米国フィラデルフィア市
    • Year and Date
      2010-12-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] Molecular Motor KIF17 is Essential for Memory and Learning by Transporting NMDA Receptors.2010

    • Author(s)
      Yin xiling
    • Organizer
      The 50th Annual Meeting of the American Society for Cell Biology (ASCB)
    • Place of Presentation
      Pennsylvania Convention Center, Philadelphia, USA.
    • Year and Date
      2010-12-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 生命の運び屋"分子モーター"~脳の働き、体の発生、腫瘍の制御~2010

    • Author(s)
      廣川信隆
    • Organizer
      第906回科学ゼミナール
    • Place of Presentation
      電力館(東京都)
    • Year and Date
      2010-12-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] 分子モーターの新しい働きと作動機構2010

    • Author(s)
      廣川信隆
    • Organizer
      東京大学・日本電子産学連携室設立5周年記念シンポジウム
    • Place of Presentation
      東京大学武田ホール(東京都)
    • Year and Date
      2010-12-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] 分子モーターから観た生命:細胞内物質輸送から脳機能、神経回路形成、発生の制御そして作動機構まで2010

    • Author(s)
      廣川信隆
    • Organizer
      第33回日本分子生物学会フォーラム
    • Place of Presentation
      神戸ポートアイランド(神戸市)
    • Year and Date
      2010-10-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 生命の要、"分子モーター":細胞内物質輸送から脳機能、神経回路形成、発生の制御そして作動機構まで2010

    • Author(s)
      廣川信隆
    • Organizer
      第6回生命科学セミナー
    • Place of Presentation
      東京薬科大学(東京都)
    • Year and Date
      2010-09-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 生命の要、分子モーターと細胞内輸送:高次脳機能、神経発生、体の左右決定そして腫瘍の制御2010

    • Author(s)
      廣川信隆
    • Organizer
      第57回日本臨床検査医学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都)(特別講演)
    • Year and Date
      2010-09-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] KIF17によるNMDA受容体輸送と記憶・学習の制御2010

    • Author(s)
      廣川信隆
    • Organizer
      第33回日本神経科学大会・第53回日本神経科学会大会・第20回日本神経回路学会大会
    • Place of Presentation
      神戸国際展示場(神戸市)
    • Year and Date
      2010-09-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規キネシンスーパーファミリーモータータンパク群KIF26Aによる腸管神経節の発生制御2010

    • Author(s)
      丹羽伸介
    • Organizer
      第33回日本神経科学学会大会
    • Place of Presentation
      神戸コンベンションセンター(神戸市)
    • Year and Date
      2010-09-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] 分子モーターが誘う未知の世界~脳の働きから体の発生まで~2010

    • Author(s)
      廣川信隆
    • Organizer
      新潟大学医学部創立100周年記念講演会
    • Place of Presentation
      新潟県民会館大ホール(新潟市)
    • Year and Date
      2010-07-06
    • Related Report
      2010 Annual Research Report
  • [Presentation] Intracellular transport and kinesin superfamily proteins, KIFs : Functions, regulations and mechanism of motility.2010

    • Author(s)
      N.Hirokawa.
    • Organizer
      Traffic Symposium, "Future Directions in Cellular Traffcking."
    • Place of Presentation
      京都大学(京都市)
    • Year and Date
      2010-06-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規キネシンスーパーファミリーたんぱく質群KIF26Aは腸管神経系のGDNF-Retシグナル伝達を制御する2010

    • Author(s)
      丹羽伸介
    • Organizer
      第62回日本細胞生物学会大会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2010-05-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Intracellular transport in the axon and dendrites by KIF1A/1B beta and KIF17 and higher brain function.2010

    • Author(s)
      N.Hirokawa.
    • Organizer
      The 2010 Cold Spring Harbor Asia Symposium
    • Place of Presentation
      Conference Center, Cold Spring Harbor Asia, Suzhou, China
    • Year and Date
      2010-04-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] KIF26Aは腸管神経系の発生においてGDNF-Retシグナルを制御する2010

    • Author(s)
      丹羽伸介、周如贇、本間典子、武井陽介、廣川信隆
    • Organizer
      第115回日本解剖学会総会
    • Place of Presentation
      岩手県民会館(岩手県盛岡市)
    • Year and Date
      2010-03-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] Kinesin superfamily protein 26A(KIF26A): A key regulator of GDNF-Ret signaling in enteric neuronal development2010

    • Author(s)
      Zhou Ruyun, Niwa Shinsuke, Homma Noriko, Takei Yosuke, Nobutaka Hirokawa
    • Organizer
      東京大学グローバルCOE「生体シグナルを基盤とする統合生命学」国際シンポジウム2010および第3回リトリート
    • Place of Presentation
      東京大学・安田講堂(東京都文京区)
    • Year and Date
      2010-03-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] Functional analysis of KIF1A KO mouse2010

    • Author(s)
      Niwa Shinsuke, Tanaka Yosuke, Dong Ming, Nobutaka Hirokawa
    • Organizer
      東京大学グローバルCOE「生体シグナルを基盤とする統合生命学」国際シンポジウム2010および第3回リトリート
    • Place of Presentation
      東京大学・安田講堂(東京都文京区)
    • Year and Date
      2010-03-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] Molecular Motor KIF17 Is Essential for Memory and Learning by Transporting NMDA Receptors2010

    • Author(s)
      Xiling Yin, Yosuke Takei, Mizuho A.Kido, Nobutaka Hirokawa
    • Organizer
      東京大学グローバルCOE「生体シグナルを基盤とする統合生命学」国際シンポジウム2010および第3回リトリート
    • Place of Presentation
      東京大学・安田講堂(東京都文京区)
    • Year and Date
      2010-03-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] Functional analysis of a kinesin motor protein, KIF16B2010

    • Author(s)
      Hitoshi Ueno, Xiao Huang, Yosuke Tanaka, Nobutaka Hirokawa
    • Organizer
      東京大学グローバルCOE「生体シグナルを基盤とする統合生命学」国際シンポジウム2010および第3回リトリート
    • Place of Presentation
      東京大学・安田講堂(東京都文京区)
    • Year and Date
      2010-03-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] The mechanism of regulation of transport and motility : lessons from Kinesin superfamily proteins KIF1A/KIF1B beta and KIF172010

    • Author(s)
      廣川信隆
    • Organizer
      54th American Society for Biophysics Annual Meeting
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2010-02-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] Kinesin superfamily molecular motors, KIFs and intracellular transport : Mechanism of motility.2010

    • Author(s)
      N.Hirokawa.
    • Organizer
      2010 Keystone Symposia Meeting, "Structural Genomics : Expanding the Horizons of Structural Biology."
    • Place of Presentation
      Beaver Run Resort, Breckenridge, Colorado, USA.
    • Year and Date
      2010-01-12
    • Related Report
      2010 Final Research Report
  • [Presentation] Kinesin superfamily molecular motors, KIFs and intracellular transport : Mechanism of motility2010

    • Author(s)
      廣川信隆
    • Organizer
      2010 Keystone Symposia Meeting, "Structural Genomics : Expanding the Horizons of Structural Biology"
    • Place of Presentation
      Breckenridge, Colorado, USA
    • Year and Date
      2010-01-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] Intracellular transport and kinesin superfamily proteins, KIFs : Structure, dynamics and functions2009

    • Author(s)
      廣川信隆
    • Organizer
      International Symposium, "Membranes and Modules"
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2009-12-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] Manipulation of Neuronal Vesicular Transport and the Mechanism of KIF5-Driven Polarized Axonal Transport2009

    • Author(s)
      T.Nakata, N.Hirokawa
    • Organizer
      49th AnnuAl Meeting of the American Society for Cell Biology
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2009-12-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] Novel Kinesin Superfamily Protein 26a(KIF26a): A Key Regulator of GDNF-Ret Signaling in Enteric Neuronal Development2009

    • Author(s)
      R.Zhou, S.Niwa, N.Homma, Y.Takei, N.Hirokawa
    • Organizer
      49th Annual Meeting of the American Society for Cell Biology
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2009-12-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] 神経細胞内の物質輸送とモーター分子群、KIFs:構造、動態、機能及び制御2009

    • Author(s)
      廣川信隆
    • Organizer
      第28回日本認知症学会
    • Place of Presentation
      東北大学百周年記念会館大ホール(宮城県仙台市)
    • Year and Date
      2009-11-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] Intracellular transport and kinesin superfamily molecular motors(KIFs): Structure, dynamics, and functions2009

    • Author(s)
      廣川信隆
    • Organizer
      XXII Annual Meeting of Society of Cell Biology of Chile
    • Place of Presentation
      Pucon, Chile
    • Year and Date
      2009-11-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] Molecular mechanism of change-over regulation between slow/fast axonal transport2009

    • Author(s)
      Sumio Terada, Masataka Kinjo, Makoto Aihara, Yosuke Takei, Nobutaka Hirokawa
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2009-09-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] 分子モーターキネシンのヌクレオチド交換機構の構造モデル2009

    • Author(s)
      仁田亮, 廣川信隆
    • Organizer
      日本顕微鏡学会
    • Place of Presentation
      仙台国際センター(官城県仙台市)
    • Year and Date
      2009-05-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] Regulation of intracellular transport of synaptic vesicle precursors abd glutamate receptors by kinesin superfamily protein, KIFs2009

    • Author(s)
      廣川信隆
    • Organizer
      29th Blankenese Conference, "proteins Processing Meets Synaptic Transmission"
    • Place of Presentation
      Hamburg-Blankenese, Germany
    • Year and Date
      2009-05-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] 神経細胞突起伸長における微小管脱重合化酵素KIF2Aとホスファチジルイノシトール4リン酸5キナーゼβとの相互作用2009

    • Author(s)
      野田泰子、本間典子、福田宏之、大海忍、廣川信隆
    • Organizer
      第114回日本解剖学会総会・全国学術集会
    • Place of Presentation
      岡山理科大学(岡山市)
    • Year and Date
      2009-03-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] 分子モーターキネシンのヌクレオチド交換過程の構造的基盤2009

    • Author(s)
      仁田亮
    • Organizer
      東京大学生命科学研究ネットワークシンポジウム2008
    • Place of Presentation
      東京大学安田講堂
    • Year and Date
      2009-03-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] 分子モーターから観た生命 : 細胞内物質輸送から脳機能、回路形成、発生の制御そして作動機構まで2009

    • Author(s)
      廣川信隆
    • Organizer
      第114回日本解剖学会総会・全国学術集会
    • Place of Presentation
      岡山理科大学(岡山市)(特別講演)
    • Year and Date
      2009-03-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] ミトコンドリァの輸送と細胞内トラフィックの分子機構2009

    • Author(s)
      田中庸介、廣川信隆
    • Organizer
      第114回日本解剖学会総会・全国学術集会(シンポジウム)
    • Place of Presentation
      岡山理科大学(岡山市)
    • Year and Date
      2009-03-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] 分子モーターキネシンのヌクレオチド交換過程の構造的基盤2009

    • Author(s)
      仁田亮、岡田康志、廣川信隆
    • Organizer
      第114回日本解剖学会総会・全国学術集会
    • Place of Presentation
      岡山理科大学(岡山市)
    • Year and Date
      2009-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin2008

    • Author(s)
      R. Nitta, Y. Okada, and N. Hirokawa
    • Organizer
      ASCB(The American Society fro Cell Biology) 49th Annual Meeting
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2008-12-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] Plasma Membrane-Microtubule Coupling by PIP5KB and KIF2A is Essential for Proper Neurite Elongation2008

    • Author(s)
      Noda Y, Homma N, Fukuda H, Imajo-Ohmi S and Hirokawa N
    • Organizer
      ASCB(The American Society fro Cell Biology) 49th Annual Meeting
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2008-12-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] 脊椎動物左右軸決定の物質的基盤、ノード小胞的発見2008

    • Author(s)
      田中庸介、岡田康志、廣川信隆
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(シンポジウム)
    • Place of Presentation
      神戸ポートアイランド(神戸市)
    • Year and Date
      2008-12-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] Intracellular transport and kinesin superfamily molecular motors, KIFs : from control of brain function and development to left/right determination and suppression of tumorigenasis2008

    • Author(s)
      Nobutaka Hirokawa
    • Organizer
      Samuel Lunenfeld Research Institute Lecture
    • Place of Presentation
      University of Toronto, Canada(invited lecture)
    • Year and Date
      2008-11-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] The molecular motors, key for life : Syructure, Dynamics and Functions2008

    • Author(s)
      Nobutaka Hirokawa
    • Organizer
      APMC9(The 9th Asia-Pacific Microscopy Conference)
    • Place of Presentation
      Jeju, Korea(Plenary Lecture)
    • Year and Date
      2008-11-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 生命の要、ミクロの運び屋、分子モーター二脳の形成、高次機能(記憶・学習)の制御から、体の左右の決定、腫瘍・癌の抑制まで2008

    • Author(s)
      廣川信隆
    • Organizer
      サイエンスカフェ(日本学術会議主催)
    • Place of Presentation
      文部科学省情報ひろばラウンジ(東京)
    • Year and Date
      2008-10-24
    • Related Report
      2008 Annual Research Report
  • [Presentation] Intracelluar transport and molecular motors, Kinesin Superfamily Proteins(KIFs) : Structure, dynamics and functions2008

    • Author(s)
      Nobutaka Hirokawa
    • Organizer
      The 9th International Congress on Cell Biology & The 20th Annual Conference of the Korean Society for Molecular and Cellular Biology
    • Place of Presentation
      COEX, Seoul, Korea(Plenary lecture)
    • Year and Date
      2008-10-08
    • Related Report
      2008 Annual Research Report
  • [Presentation] The cutting edge of life science research in health and diseases : molecular motors, key molecules in life2008

    • Author(s)
      Nobutaka Hirokawa
    • Organizer
      ドイツチューリンゲン州光学・医療フォーラム2008
    • Place of Presentation
      ウェスティンホテル東京(東京)
    • Year and Date
      2008-10-01
    • Related Report
      2008 Annual Research Report
  • [Presentation] The basic medical science in the 21th century, an example of multidisciplinary life science research in Japan2008

    • Author(s)
      Nobutaka Hirokawa
    • Organizer
      The Japan Academy-The National Academy of Scieneces, Republic of Korea Science Forum
    • Place of Presentation
      日本学士院
    • Year and Date
      2008-09-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] Human Frontier Science Program Lecture.2008

    • Author(s)
      N.Hirokawa.
    • Organizer
      6^<th> FENS (Forum of European Neuroscience).
    • Place of Presentation
      Geneva, Switzerland.
    • Year and Date
      2008-07-13
    • Related Report
      2010 Final Research Report
  • [Presentation] The intraneuronal transport and kinesin superfamily proteins, KIFs : from brain wiring and development to higher brain function2008

    • Author(s)
      Nobutaka Hirokawa
    • Organizer
      Human Frontier Science Program Lecture(Special lecture)/6th FENS(Forum of European Neuroscience)
    • Place of Presentation
      Geneva, Switzerland
    • Year and Date
      2008-07-13
    • Related Report
      2008 Annual Research Report
  • [Presentation] Intraneuronal transport and molecular motors, KIFs : from Brain wiring and development to higher brain function2008

    • Author(s)
      Nobutaka Hirokawa
    • Organizer
      8th Biennial meeting of Asia-Pasific Society for Neurochemistry(APSN)
    • Place of Presentation
      Shanghai, China(Plenary lecture)
    • Year and Date
      2008-06-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] 分子モーターから観た"生命科学" : 体の左右非対称性の決定機構を中心に2008

    • Author(s)
      廣川信隆
    • Organizer
      フォーラム「新・地球学の世紀」
    • Place of Presentation
      元町館4階「スペースU」(東京都)
    • Year and Date
      2008-06-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] 発生の要、モーター分子群Kinesin superfamily protehls, KIFs2008

    • Author(s)
      廣川信隆
    • Organizer
      第45回小児外科学会学術集会
    • Place of Presentation
      つくば国際会議場(つくば市)(特別講演)
    • Year and Date
      2008-05-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] 分子モーターから観た生命科学2008

    • Author(s)
      廣川信隆
    • Organizer
      日本顕微鏡学会第64回学術講演会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2008-05-21
    • Related Report
      2008 Annual Research Report
  • [Presentation] Intracellular transport and molecular motors, Kinesin superfamily proteins (KIFs) : Structure, dynamics, and functions2008

    • Author(s)
      Nobutaka Hirokawa
    • Organizer
      Ibdai-Tsinghua 2008, Todai Week at Tsinghua
    • Place of Presentation
      Tsinghua University, Beijing, CHINA(Plenary lecture)
    • Year and Date
      2008-05-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] Intracellular transport and molecular motors, Kinesin Superfamily Proteins(KIFs) : Structure, dynamics, and functions2008

    • Author(s)
      Nobutaka Hirokawa
    • Organizer
      5th Asian-Pacific International Congress of Anatomists
    • Place of Presentation
      Tehran, IRAN(Plenary lecture)
    • Year and Date
      2008-05-16
    • Related Report
      2008 Annual Research Report
  • [Presentation] 細胞内物質輸送と分子モーター2008

    • Author(s)
      廣川信隆
    • Organizer
      第109回日本耳鼻咽喉学会総会・学術講演会
    • Place of Presentation
      大阪国際会議場(大阪)(特別講演)
    • Year and Date
      2008-05-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] 原始結節の線毛とKIF3モーター、そして左右非対称性2008

    • Author(s)
      廣川信隆
    • Organizer
      第113回日本解剖学会総会・全国学術集会
    • Place of Presentation
      大分大学医学部
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] Intracellular transport and Kinesin Superfamily proteins, KIFs: Structure, dynamics, and function2008

    • Author(s)
      N. Hirokawa
    • Organizer
      4th International Conference on structural Analysis of Supramolecular Assemblies by Hybrid Methods
    • Place of Presentation
      California, USA
    • Year and Date
      2008-03-12
    • Related Report
      2007 Annual Research Report
  • [Presentation] Kinesin superfamily proteins: structure, dynamics, and function2008

    • Author(s)
      N. Hirokawa
    • Organizer
      lst International Meeting, Conformational Transitions in Macromolecular Interactions
    • Place of Presentation
      Wittenberg, Germany
    • Year and Date
      2008-02-29
    • Related Report
      2007 Annual Research Report
  • [Presentation] モーター分子群、KIFsが拓いた生命科学の新たな地平2007

    • Author(s)
      廣川信隆
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-13
    • Related Report
      2007 Annual Research Report
  • [Presentation] 生命の要、キネシンスーパーファミリーモーター分子群、KIFs-構造、機能、動態-2007

    • Author(s)
      廣川信隆
    • Organizer
      第34回日本臨床バイオメカニクス学会(特別講演)
    • Place of Presentation
      早稲田大学国際会議場
    • Year and Date
      2007-12-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] Proposed Mechanism of Regulation of Nucleotide Exchange in the Kinesin/Microtubule System2007

    • Author(s)
      Ryo Nitta, 他2名
    • Organizer
      American Society for Cell Biology 47th Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2007-12-02
    • Related Report
      2007 Annual Research Report
  • [Presentation] Disruption of KIF17-Mint1 interaction by CaMKII-dependent phosphorylation.2007

    • Author(s)
      Laurent Guillaud and N. Hirokawa
    • Organizer
      47th ASCB Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2007-12-02
    • Related Report
      2007 Annual Research Report
  • [Presentation] Intracellular transport of mRNA and kinesin superfamily proteins, KIFs2007

    • Author(s)
      N. Hirokawa
    • Organizer
      HHMI (Howard Hughus Medical Institute) Janelia Farm Conference
    • Place of Presentation
      Washington D.C, USA
    • Year and Date
      2007-10-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] 分子モーターキネシンの動作機構の構造的基盤2007

    • Author(s)
      仁田 亮, 他2名
    • Organizer
      東京大学生命科学研究ネットワークシンポジウム2007
    • Place of Presentation
      東京大学
    • Year and Date
      2007-09-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] 脊椎動物左右軸決定の物質的基盤・ノード小胞の発見2007

    • Author(s)
      田中庸介, 他2名
    • Organizer
      平成19年度東京大学生命科学ネットワークシンポジウム
    • Place of Presentation
      東京大学
    • Year and Date
      2007-09-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] 分子モーターKIF1A低発現マウスの作成2007

    • Author(s)
      田中庸介, 他4名
    • Organizer
      平成19年度東京大学生命科学ネットワークシンポジウム
    • Place of Presentation
      東京大学
    • Year and Date
      2007-09-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] ミクロの運び屋"分子モーター"が開く未知の世界;細胞から生命を観る2007

    • Author(s)
      廣川信隆
    • Organizer
      日本学術会議分科会合同シンポジウム
    • Place of Presentation
      東京大学小柴ホール
    • Year and Date
      2007-09-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] Proposed Mechanism of Regulation of Nucleotide Exchange in the Kinesin/Microtubule System.2007

    • Author(s)
      Ryo Nitta, 他2名
    • Organizer
      56th Fujihara Seminar: The Molecular Motor Conference 2007
    • Place of Presentation
      Tomakomai, Japan
    • Year and Date
      2007-08-24
    • Related Report
      2007 Annual Research Report
  • [Presentation] Establishment of New Hypomorphic Mouse Model for KIF1A Molec ular Motor2007

    • Author(s)
      Tanaka Y., 他4名
    • Organizer
      47th ASCB Annual Meeting
    • Place of Presentation
      Tomakomai, Japan
    • Year and Date
      2007-08-24
    • Related Report
      2007 Annual Research Report
  • [Presentation] Molecular notors, KIFs, intracellulartransport and neuronal function: higher brain function, brain wiring and activity dependent neuronal survival2007

    • Author(s)
      N. Hirokawa
    • Organizer
      7th IBRO World Congress of Neuroscience.
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2007-07-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] Intracellular trasnport of mRNA and kinesin superfamily proteins, KIFs2007

    • Author(s)
      N. Hirokawa
    • Organizer
      7th IBRO World Congress of Neuroscience.
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2007-07-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] Integrative biology of Kinesin superfami;y molecular motors, KIFs: Structure, dynamics and fiunctions2007

    • Author(s)
      N. Hirokawa
    • Organizer
      International Symposium on Advanced and Integrative Life Sciences
    • Place of Presentation
      University of Tokyo
    • Year and Date
      2007-07-10
    • Related Report
      2007 Annual Research Report
  • [Presentation] Intracellular transport and kinesin superfamily proteins: Structure, dynamics, and function2007

    • Author(s)
      N. Hirokawa
    • Organizer
      Albany 2007, the 15th Conversation
    • Place of Presentation
      NewYork, USA
    • Year and Date
      2007-06-21
    • Related Report
      2007 Annual Research Report
  • [Presentation] 細胞内物質輸送とキネシンスーパーファミリーモーター分子群、KIFS:構造、機能、動態2007

    • Author(s)
      廣川信隆
    • Organizer
      第80回日本内分泌学会学術総会(マイスター賞受賞講演)
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2007-06-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] KIF3 motor, cilia and determination of left/right asymmetry2007

    • Author(s)
      N. Hirokawa
    • Organizer
      The 22nd Sgrid Juselius International Symposium
    • Place of Presentation
      Espoo, Finland
    • Year and Date
      2007-06-04
    • Related Report
      2007 Annual Research Report
  • [Presentation] Intracellular transport and kinesin superfamily proteins, KIFs: structure, dynamics, and function2007

    • Author(s)
      N. Hirokawa
    • Organizer
      Days of Molecular Medicine 2007, Emerging Technologies and Cancer Biology
    • Place of Presentation
      Massachusetts, USA
    • Year and Date
      2007-05-24
    • Related Report
      2007 Annual Research Report
  • [Presentation] 左右決定イベントの物質的基盤、ノード小胞の同定2007

    • Author(s)
      田中庸介, 他2名
    • Organizer
      日本顕微鏡学会第63回学術講演会(招待講演)
    • Place of Presentation
      新潟
    • Year and Date
      2007-05-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] 神経細胞物質輸送の分子細胞生物学:メカニズムとその障害2007

    • Author(s)
      廣川信隆
    • Organizer
      第48回日本神経学会総会(招待講演)
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2007-05-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] Intracellular transport and kinesin superfamily proteins, KIFs: Strusture, dynamics, functions, and diseases.2007

    • Author(s)
      N. Hirokawa
    • Organizer
      102th Annual Meeting of the Anatomische Gesellschaft. EFEM
    • Place of Presentation
      Giessen, Germany
    • Year and Date
      2007-04-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] Nobel Mini Symposium 38- Frontiers in Medicine Series.2006

    • Author(s)
      N.Hirokawa.
    • Organizer
      Active Dendrites.
    • Place of Presentation
      Stockholm, Sweden.
    • Year and Date
      2006-05-18
    • Related Report
      2010 Final Research Report
  • [Book] Cold Spring Harber Perspectives in Biology.(Left-Right determination : Involvement of molecular motor KIF3, cilia, and nodal flow.)2009

    • Author(s)
      Hirokawa, N., Y.Tanaka, Y.Okada.
    • Related Report
      2010 Final Research Report
  • [Book] Methods in Cell Biology(Observation of Nodal Cilia Movement and Measurement of Nodal Flow)2009

    • Author(s)
      Okada, Y., N.Hirokawa
    • Total Pages
      332
    • Related Report
      2009 Annual Research Report
  • [Book] Controlled Nanoscale Motion, Lecture Notes in Physics, Nobel Symposium 131(Intracellular transport and kinesinsuperfamily proteins : structure, function and dynamics.)(edt by H.Linke, A.Mansson)2007

    • Author(s)
      Hirokawa, N., R.Takemura.
    • Total Pages
      711
    • Publisher
      Springer-Verlag
    • Related Report
      2010 Final Research Report
  • [Book] Controlled Nanoscale Motion, Lecture Notes in Physics, Nobel Symposium 1312007

    • Author(s)
      Hirokawa, N. and R. Takemura
    • Publisher
      Springer-Verlag
    • Related Report
      2007 Annual Research Report
  • [Book] 学問の扉 東京大学は挑戦する2007

    • Author(s)
      廣川信隆ほか
    • Publisher
      講談社
    • Related Report
      2007 Annual Research Report
  • [Remarks] ホームページ

    • URL

      http://cb.m.u-tokyo.ac.jp/

    • Related Report
      2010 Final Research Report
  • [Remarks] 毎日新聞2006年4月21日

    • Related Report
      2008 Self-evaluation Report
  • [Remarks] 朝日新聞2006年10月29日

    • Related Report
      2008 Self-evaluation Report
  • [Remarks] 読売新聞2007年9月9日

    • Related Report
      2008 Self-evaluation Report
  • [Remarks] 毎日新聞2008年1月13日

    • Related Report
      2008 Self-evaluation Report
  • [Remarks] 朝日新聞2008年1月18日

    • Related Report
      2008 Self-evaluation Report

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Published: 2006-04-01   Modified: 2018-03-28  

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