Catalysis of Active Site Models of Metalloenzymes Containing Dinuclear Metal Chalcogenide

• Project/Area Number: 18065013
• Research Category: Grant-in-Aid for Scientific Research on Priority Areas
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Nagoya University
• Principal Investigator: MATSUMOTO Tsuyoshi Nagoya University, 大学院・理学研究科, 助教 (50311717)
• Project Period (FY): 2006 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥32,000,000 (Direct Cost: ¥32,000,000); Fiscal Year 2009: ¥8,000,000 (Direct Cost: ¥8,000,000); Fiscal Year 2008: ¥8,000,000 (Direct Cost: ¥8,000,000); Fiscal Year 2007: ¥8,000,000 (Direct Cost: ¥8,000,000); Fiscal Year 2006: ¥8,000,000 (Direct Cost: ¥8,000,000)
• Keywords: 二核錯体 / カルコゲニド / 金属酵素活性中心 / モデル反応 / 協奏機能触媒 / 複核金属錯体 / チオラート / アセチルCoA合成酵素 / ニッケル錯体 / アセチルチオエステル / 協奏機能 / 炭酸固定 / 酵素モデル / 協同作用 / カルコゲン / ヒドロゲナーゼ / 水素分子活性化 / 架橋スルフィド / 異核二核錯体 / ルテニウム / ゲルマニウム

Research Abstract

We have synthesized hetero-dinuclear complexes modeling of the active sites of [NiFe] hydrogenase and acetyl CoA synthase to elucidate the mechanisms of the enzyme functions. The dinuclear Ge/Ru complex bridged by S/OH activates dihydrogen molecule under mild conditions, and their reaction mechanism was investigated. The studies of dinuclear nickel complexes indicates a plausible mechanism of the catalytic pathway of acetyl CoA synthase.

Research Products

• [Journal Article] A Dinuclear Nickel Complex Modeling of the Ni_d(II)-Ni_p(I) State for the Active Site of Acetyl CoA Synthase (2010)
  • Author(s): Matsumoto, T.; Ito, M.; Kotera, M.; Tatsumi, K.
  • Journal Title: Dalton Trans. 39 Pages: 2995-2997
  • Peer Reviewed
• [Journal Article] Synthesis and Reactions of Mono- and Dinuclear Nickel(I) Thiolate Complexes (2010)
  • Author(s): Matsumoto, T.; Ito, M.; Kotera, M.; Tatsumi, K.
  • Journal Title: Dalton Trans. 39 Pages: 2995-2997
  • Peer Reviewed
• [Journal Article] Host plant genome overcomes the lack of bacterial gene for symbiotic nitrogen fixation (2009)
  • Author(s): Hakoyama, T.; Niimi, K.; Watanabe, H.; Tabata, R.; Matsubara, J.; Sato, S.; Nakamura, Y.; Tabata, S.; Li, J.; Matsumoto, T.; Tatsumi, K.; Nomura, M.; Tajima, S.; Ishizaka, M; Yano, K.; Imaizumi-Anraku, H.; Kawaguchi, M.; Kouchi, H.; Suganuma, N.
  • Journal Title: Nature 462 Pages: 514-517
  • NAID: 120002146280
  • Peer Reviewed
• [Journal Article] Acetyl CoA Synthase, a Key Player of Carbon Fixation in Nature (2009)
  • Author(s): Matsumoto, T.
  • Journal Title: Bull. Jpn. Soc. Coord. Chem. 54(Review) Pages: 38-51
  • NAID: 130000248073
  • Peer Reviewed
• [Journal Article] Evidence for a Rapid Degenerate Hetero-Cope-type Rearrangement in Cp*W(S)_2-CH_2-CH_2-CH=CH_2 (2009)
  • Author(s): Eweiner, F.; Senda, S.; Bergander, K.; Muck-Lichtenfeld, C.; Grimme, S.; Frohlich, R.; Aoyama, M.; Kawaguchi, H.; Ohki, Y.; Matsumoto, T.; Kehr, G.; Tatsumi, K.; Erker, G.
  • Journal Title: Chem. Asian J. 4 Pages: 1830-1833
  • Peer Reviewed
• [Journal Article] Dinuclear Nickel Complexes Modeling the Structure and Function of the Acetyl CoA Synthase Active-Site (2009)
  • Author(s): Ito, M.; Kotera, M.; Matsumoto, T.; Tatsumi, K.
  • Journal Title: Proc. Nat. Acad. Sci. USA. 106 Pages: 11862-11866
  • Peer Reviewed
• [Journal Article] Organometallic Chemistry in [NiFe] Hydrogenases: Synthesis of the Structural and Functional Models (2009)
  • Author(s): Matsumoto, T.; Ohki, Y.; Tatsumi, K.
  • Journal Title: J. Syn. Org. Chem. Jpn. 67 Pages: 540-553
  • NAID: 10024969046
  • Peer Reviewed
• [Journal Article] Synthesis and Reactions of Mono- and Dinuclear Nickel(I) Thiolate Complexes (2009)
  • Author(s): Ito, M.; Matsumoto, T.; Tatsumi, K.
  • Journal Title: Inorg. Chem. 48 Pages: 2215-2223
  • Peer Reviewed
• [Journal Article] Cationic and Anionic Dinuclear Nickel Complexes [Ni(N_2S_2)Ni(dtc)]^n (n =-1, +1) Modeling the Active Site of Acetyl-CoA Synthase (2009)
  • Author(s): Song, Y.; Ito, M.; Kotera, M.; Matsumoto, T.; Tatsumi, K.
  • Journal Title: Chem. Lett. 38 Pages: 184-185
  • NAID: 10025119498
  • Peer Reviewed
• [Journal Article] Structural Models for the Active Site of Acetyl-CoA Synthase: Synthesis of Dinuclear Nickel Complexes having Thiolate, Isocyanide, and Thiourea on the Ni_p Site (2009)
  • Author(s): Ito, M.; Kotera, M.; Song, Y.; Matsumoto, T.; Tatsumi, K.
  • Journal Title: Inorg. Chem. 48 Pages: 1250-1256
  • Peer Reviewed
• [Journal Article] Organometallic Chemistry in [NiFe] Hydrogenases : Synthesis of the Structural and Functional Models. (2009)
  • Author(s): Matsumoto, T.; Ohki, Y.; Tatsumi, K.
  • Journal Title: J.Syn.Org.Chem.Jpn. 67 Pages: 540-553
  • NAID: 10024969046
  • Peer Reviewed
• [Journal Article] Dinuclear Nickel Complexes Modeling the Structure and Function of the Acetyl CoA Synthase Active-Site. (2009)
  • Author(s): Ito, M.; Kotera, M.; Matsumoto, T.; Tatsumi, K.
  • Journal Title: Proc.Nat.Acad.Sci.USA. 106 Pages: 11862-11866
  • Peer Reviewed
• [Journal Article] Evidence for a Rapid Degenerate Hetero-Cope-type Rearrangement in Cp^*W(S)_2-CH_2-CH_2-CH=CH_2. (2009)
  • Author(s): Eweiner, F.; Matsumoto, T.; Kehr, G.; Tatsumi, K.; Erker, G., 他
  • Journal Title: Chem.Asian J. 4 Pages: 1830-1833
  • Peer Reviewed
• [Journal Article] Synthesis and Reactions of Mono- and Dinuclear Nickel(I) Thiolate Complexes (2009)
  • Author(s): Hakoyama, T.; Matsumoto, T.; Tatsumi, K.; Suaanuma, N., 他
  • Journal Title: Nature 462 Pages: 514-517
  • Peer Reviewed
• [Journal Article] Synthesis and Reactions of Mono- and Dinuclear Nickel(I) Thiolate Complexes (2009)
  • Author(s): Ito, M.; Matsumoto, T.; Tatsumi, K.
  • Journal Title: Inorg.Chem. 48 Pages: 2215-2223
  • Peer Reviewed
• [Journal Article] Cationic and Anionic Dinuclear Nickel Complexes [Ni(N_2S_2)Ni(dtc)]^n (n = -1, +1) Modeling the Active Site of Acetyl-CoA Synthase (2009)
  • Author(s): Song, Y.; Ito, M.; Kotera, M.; Matsumoto, T.; Tatsumi, K.
  • Journal Title: Chem.Lett. 38 Pages: 184-185
  • NAID: 10025119498
  • Peer Reviewed
• [Journal Article] Structural Models for the Active Site of Acetyl-CoA Synthase: Synthesis of Dinuclear Nickel Complexes having Thiolate, Isocyanide, and Thiourea on the Ni_p Site (2009)
  • Author(s): Ito, M.; Kotera, M.; Song, Y.; Matsumoto, T.; Tatsumi, K.
  • Journal Title: Inorg.Chem. 48 Pages: 1250-1256
  • Peer Reviewed
• [Journal Article] Structural Models for the Active Site of Acetyl-CoA Synthase : Synthesis of Dinuclear Nickel Complexes Having Thiolate, Isocyanide, and Thiourea on the Ni_p Site (2009)
  • Author(s): Ito, M. ; Kotera, M. ; Song, Y. ; Matsumoto, T. ; Tatsumi, K.
  • Journal Title: Inorg. Chem. 48 Pages: 1250-1256
  • Peer Reviewed
• [Journal Article] Cationic and Anionic Dinuclear Nickel Complexes [Ni (N_2S_2) Ni (dtc)]^n (n=- 1, + 1) Modeling the Active Site of Acetyl-CoA Synthase (2009)
  • Author(s): Song, Y. ; Ito, M. ; Kotera, M. ; Matsumoto, T. ; Tatsumi, K.
  • Journal Title: Chem. Lett. 38 Pages: 184-185
  • NAID: 10025119498
  • Peer Reviewed
• [Journal Article] Synthesis and Reactions of Mono- and Dinuclear Nickel (I) Thiolate Complexes (2009)
  • Author(s): Ito, M. ; Matsumoto, T. ; Tatsumi, K.
  • Journal Title: Inorg. Chem. 48 Pages: 2215-2223
  • Peer Reviewed
• [Journal Article] Synthesis of Ge_2NiS_4 Clusters and the Thermal Transformation to a Ge_4Ni_6S_<12> Cluster (2008)
  • Author(s): Matsumoto, T.; Matsui, Y., Ito, M.; Tatsumi, K.
  • Journal Title: Inorg. Chem. 47 Pages: 1901-1903
  • Peer Reviewed
• [Journal Article] A Functional Hydrogenase Model: Reversible Interconversion of H_2 and H_2O by a Hydroxo/Sulfido-Bridged Dinuclear Ruthenium-Germanium Complex (2008)
  • Author(s): Matsumoto, T.; Nakaya, Y.; Itakura, N.; Tatsumi, K.
  • Journal Title: J. Am. Chem. Soc. 130 Pages: 2458-2459
  • Peer Reviewed
• [Journal Article] Heterolytic Dihydrogen Activation by a Sulfido- and Oxo-Bridged Dinuclear Germanium-Ruthenium Complex (2008)
  • Author(s): Matsumoto, T.; Nakaya, Y.; Tatsumi, K.
  • Journal Title: Angew. Chem. Int. Ed. 47 Pages: 1913-1915
  • Peer Reviewed
• [Journal Article] Synthesis of syn-2, 4-Dimercapto-1, 3, 2, 4- dithiadigermetane and Its Application for Ge_2PdS_4 Cluster Synthesis (2008)
  • Author(s): Matsumoto, T.; Matsui, Y.; Ito, M.; Tatsumi, K.
  • Journal Title: Chem. Asian J. 3 Pages: 607-613
  • Peer Reviewed
• [Journal Article] Synthesis of Ge_2NiS_4 Clusters and the Thermal Transformation to a Ge_4Ni_6S_<12> Cluster (2008)
  • Author(s): Matsumoto, T.; Matsui, Y., Ito, M.; Tatsumi, K.
  • Journal Title: Inorg.Chem. 47 Pages: 1901-1903
  • Peer Reviewed
• [Journal Article] A Functional Hydrogenase Model : Reversible Interconversion of H_2 and H_2O by a Hydroxo/Sulfido-Bridged Dinuclear Ruthenium-Germanium Complex (2008)
  • Author(s): Matsumoto, T.; Nakaya, Y.; Itakura, N.; Tatsumi, K.
  • Journal Title: J.Am.Chem.Soc. 130 Pages: 2458-2459
  • Peer Reviewed
• [Journal Article] Heterolytic Dihydrogen Activation by a Sulfido- and Oxo-Bridged Dinuclear Germanium-Ruthenium Complex (2008)
  • Author(s): Matsumoto, T.; Nakaya, Y.; Tatsumi, K.
  • Journal Title: Angew.Chem.Int.Ed. 47 Pages: 1913-1915
  • Peer Reviewed
• [Journal Article] Synthesis of syn-2,4-Dimercapto-1,3,2,4-dithiadigermetane and Its Application for Ge_2PdS_4 Cluster Synthesis (2008)
  • Author(s): Matsumoto, T.; Matsui, Y.; Ito, M.; Tatsumi, K.
  • Journal Title: Chem.Asian J. 3(Highlighted in the Cover picture) Pages: 607-613
  • Peer Reviewed
• [Journal Article] Modulation of Third-Order Nonlinear Optical Properties by Backbone Modification of Polymeric Pillared-Layer Heterometallic Clusters (2008)
  • Author(s): Zhang, C. ; Matsumoto, T. ; Tatsumi, K. 他
  • Journal Title: Adv. Mater. 20 Pages: 1870-1875
  • Peer Reviewed
• [Journal Article] Synthesis of Ge_2NiS_4 Clusters and the Thermal Transformation to a Ge_4 Ni_6S_12 Cluster (2008)
  • Author(s): Matsumoto, T.; Matsui, Y., Ito, M.; Tatsumi, K.
  • Journal Title: Inorg. Chem. 47 Pages: 1901-1903
  • Peer Reviewed
• [Journal Article] Synthesis of syn-2,4-Dimercapto-1,3,2,4-dithiadigermetane and Its Application for Ge_2PdS_4 Cluster Synthesis (2008)
  • Author(s): Matsumoto, T.; Matsui, Y., Ito, M.; Tatsumi, K.
  • Journal Title: Chem. Asian J. 3 Pages: 607-613
  • Peer Reviewed
• [Journal Article] Heterolytic Dihydrogen Activation by a Sulfido-and Oxo-Bridged Dinuclear Germanium-Ruthenium Complex (2008)
  • Author(s): Matsumoto, T.; Nakaya, Y.; Tatsumi, K.
  • Journal Title: Angew. Chem. Int. Ed. 47 Pages: 1913-1915
  • Peer Reviewed
• [Journal Article] Dinuclear Nickel Complexes Modeling Acetyl-CoA Synthase (2007)
  • Author(s): Matsumoto, T.; Ito, M.; Tatsumi, K.
  • Journal Title: J. Biol. Inorg. Chem. 12 Pages: 121-122
• [Journal Article] Nickel(II) Thiolate Complexes with a flexible cyclo-{Ni_<10>S_<20>} Framework. (2006)
  • Author(s): Zhang, C.; Takada, S.; Kolzer, M.; Matsumoto, T.; Tatsumi, K.
  • Journal Title: Angew. Chem. Int. Ed. 45 Pages: 3768-3772
  • Peer Reviewed
• [Journal Article] Synthesis of Oxo- and Sulfido-Bridged Germanium-Ruthenium Complexes and Reactions on the Chalcogenido Bridges. (2006)
  • Author(s): Matsumoto, T.; Nakaya, Y.; Tatsumi, K.
  • Journal Title: Organometallics 25 Pages: 4835-4845
  • Peer Reviewed
• [Journal Article] Mono{Hydrotris(mercaptoimidazolyl) borato} Complexes of Manganese(II), Iron(II), Cobalt(II), and Nickel(II) Halides (2006)
  • Author(s): Senda, S.; Ohki, Y.; Hirayama, T.; Toda, D.; Chen, J. -T.; Matsumoto, T.; Kawaguchi, H.; Tatsumi, K.
  • Journal Title: Inorg. Chem. 45 Pages: 9914-9925
  • Peer Reviewed
• [Journal Article] Nickel(II) Thiolate Complexes with a flexible cyclo-{Ni_<10>S_<20>} Framework. (2006)
  • Author(s): Zhang, C.; Takada, S.; Kolzer, M.; Matsumoto, T.; Tatsumi, K.
  • Journal Title: Angew.Chem.Int.Ed. 45(Highlighted in the Frontispiece) Pages: 3768-3772
  • Peer Reviewed
• [Journal Article] New nickel(II) thiolates with a flexible cyclo-Ni_10S_20 framework (2006)
  • Author(s): Zhang, C., Takada, S., Kolzer, M., Matsumoto, T., Tatsumi, K.
  • Journal Title: Angew. Chem., Int. Ed. 45 Pages: 3768-3772
• [Journal Article] Synthesis of Oxo- and Sulfido-Bridged Germanium-Ruthenium Complexes and Reactions on the Chalcogenido Bridges (2006)
  • Author(s): Matsumoto, T., Nakaya, Y., Tatsumi, K.
  • Journal Title: Organometallics 25 Pages: 4835-4845
• [Journal Article] Mono{Hydrotris(mercaptoimidazolyl)borato} Complexes of Manganese(II), Iron(II), Cobalt(II), and Nickel(II) Halides (2006)
  • Author(s): Senda, S., Ohki, Y., Hirayama, T., Toda, D., Chen, J.-T., Matsumoto, T., Kawaguchi, H., Tatsumi, K.
  • Journal Title: Inorg. Chem. 45 Pages: 9914-9925
• [Presentation] Acetylthioester Formation on Dinuclear Nickel Thiolates : The Acetyl CoA Synthase Model. (2010)
  • Author(s): T.Matsumoto, S.Arae, M.Ito, K.Tatsumi
  • Organizer: Global COE-RCMS International Symposium on Organic Chemistry
  • Place of Presentation: 名古屋
  • Year and Date: 2010-01-12
• [Presentation] Acetylthioester Formation on Dinuclear Nickel Thiolates : The Acetyl CoA Synthase Model. (2010)
  • Author(s): T.Matsumoto, S.Arae, M.Ito, K.Tatsumi
  • Organizer: The 3rd International Conference on Joint Project of Chemical Synthesis Core Research Institutions
  • Place of Presentation: 名古屋
• [Presentation] Reactions of Tetraazamacrocyclic Nickel(I) Complexes Modeling Methyl Coenzyme M Reductase. (2010)
  • Author(s): J.Nishigaki, T.Matsumoto, K.Tatsumi
  • Organizer: The 3rd International Conference on Joint Project of Chemical Synthesis Core Research Institutions
  • Place of Presentation: 名古屋
• [Presentation] Dinuclear Nickel Complexes Carrying a Sulfur and a Carbon Ligands as Active Site Models of Acetyl CoA Synthase. (2010)
  • Author(s): S.Arae, T.Matsumoto, K.Tatsumi
  • Organizer: The 3rd International Conference on Joint Project of Chemical Synthesis Core Research Institutions
  • Place of Presentation: 名古屋
• [Presentation] メチル補酵素M還元酵素の活性中心モデルとなる分子内チオエーテルを持つニッケル(I)サイクラム錯体の合成と反応 (2010)
  • Author(s): 西垣潤一・松本剛・巽和行
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 東大阪
• [Presentation] アセチルCoA合成酵素のモデルとなるイソシアニド/チオラート配位Ni二核錯体の合成と反応 (2010)
  • Author(s): 荒江祥永・松本剛・巽和行
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 東大阪
• [Presentation] Dinuclear Nickel Complexes Modeling the Sructure and Function of Acetyl CoA Synthase (2009)
  • Author(s): Matsumoto, T.
  • Organizer: The 14th International Conference on Bioinorganic Chemistry (ICBIC 14)
  • Place of Presentation: 名古屋
• [Presentation] カルコゲン架橋複核錯体を利用した小分子活性化 (2009)
  • Author(s): 松本剛
  • Organizer: 日本化学会第89春季年会特別企画"若手研究者が語る次世代生物無機化学"
  • Place of Presentation: 千葉
• [Presentation] Reversible H_2 Activation by Hetero-dinuclear Ru/Ge Complexes: A Functional Hydrogenase Model (2009)
  • Author(s): Matsumoto, T.
  • Organizer: The 1^<st> G-COE International Symposium on Elucidation and Design of Materials and Molecular Functions
  • Place of Presentation: 名古屋
• [Presentation] Dinuclear Nickel Complexes Modeling the Sructure and Function of Acetyl CoA Synthase. (2009)
  • Author(s): T.Matsumoto, M.Ito, K.Tatsumi
  • Organizer: 14th International Conference on Biological Inorganic Chemistry (ICBIC14)
  • Place of Presentation: 名古屋
• [Presentation] Me-S Bond Activation by Ni(I) Cyclams Relevant to the Methyl Coenzyme M Reductase Function. (2009)
  • Author(s): J.Nishigaki, T.Matsumoto, K.Tatsumi
  • Organizer: 14th International Conference on Biological Inorganic Chemistry (ICBIC14)
  • Place of Presentation: 名古屋
• [Presentation] A Model Reaction of Methyl Coenzyme M Reductase : Intramolecular CH_3-S bond Activation by Ni(I) Cyclam Complexes Having Methylthio-Substituted Pendant Chains. (2009)
  • Author(s): J.Nishigaki, T.Matsumoto, K.Tatsumi
  • Organizer: The 8th joint seminar University of Munster-Nagoya University
  • Place of Presentation: 名古屋
• [Presentation] Activation of Dihydrogen and Carbon monoxide by the OH-bridged Ru-Ge Dinuclear Complexes (2009)
  • Author(s): T.Matsumoto, K.Tatsumi
  • Organizer: The 14^<th> Japan-Korea Joint Symposium on Organometallic and Coordination Chemistry
  • Place of Presentation: 名古屋
• [Presentation] メチル補酵素M還元酵素の反応モデル:ニッケル(I)錯体によるCH_3-S結合の活性化とメタン生成反応 (2009)
  • Author(s): 西垣潤一・松本剛・巽和行
  • Organizer: 第59回錯体化学討論会
  • Place of Presentation: 長崎
• [Presentation] メチル補酵素M還元酵素反応モデル:ニッケル(I)サイクラム錯体による分子内CH_3-S結合切断 (2009)
  • Author(s): 西垣潤一・松本剛・巽和行
  • Organizer: 第56回有機金属化学討論会
  • Place of Presentation: 京都
• [Presentation] S/0架橋Ru-Ge複核錯体によるシランおよびCO活性化 (2009)
  • Author(s): 松本剛・巽和行
  • Organizer: 第104回触媒討論会
  • Place of Presentation: 宮崎
• [Presentation] メチルCoM還元酵素モデルとなるNi(I)サイクラム錯体によるMe-S結合切断反応 (2009)
  • Author(s): 西垣潤一・松本剛・巽和行
  • Organizer: 第5回物質合成シンポジウム
  • Place of Presentation: 宇治
• [Presentation] S/0架橋二核Ge-Ru錯体によるシランおよびCO活性化 (2009)
  • Author(s): 松本剛・中谷祐希子・巽和行
  • Organizer: 第36回有機典型元素化学討論会
  • Place of Presentation: 鳥取
• [Presentation] Reversible H_2 Activation by Hetero-dinuclear Ru/Ge Complexes : A Functional Hydrogenase Model (2009)
  • Author(s): Matsumoto, T.
  • Organizer: The 1^<st> G-COE International Symposium on Elucidation and Design of Materials and Molecular Functions
  • Place of Presentation: 名古屋
• [Presentation] A Functional Models of Hydrogenase and CO Dehydrogenase : H_2 and CO Activation by Hetero-Dinuclear Ru/Ge Complexes (2009)
  • Author(s): 松本剛・巽和行
  • Organizer: 第4回物質合成シンポジウム
  • Place of Presentation: 名古屋
• [Presentation] Dinuclear Nickel Complexes modeling Acetyl-CoA Synthase (2009)
  • Author(s): 小寺林衣・伊藤幹直・宋宝梅・松本剛・巽和行
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 船橋
• [Presentation] メチル補酵素M還元酵素の反応モデル : ニッケル(I)錯体を用いたMe-S結合の活性化によるメタン生成反応 (2009)
  • Author(s): 西垣潤一・松本剛・巽和行
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 船橋
• [Presentation] Me-S Bond Activation by Ni (I) Model Complexgs : Insight into the Function of Methyl CoM Reductase (2009)
  • Author(s): J. Nishigaki, T. Matsumoto, K. Tatsumi
  • Organizer: International Symposium on Chemistry of Reductase II
  • Place of Presentation: 名古屋
• [Presentation] A Functional Models of Hydrogenase and CO Dehydrogenase : H_2 and CO Activation by Hetero-Dinuclear Ru/Ge Complexes (2009)
  • Author(s): T. Matsumoto, K. Tatsumi
  • Organizer: International Symposium on Chemistry of Reductase II
  • Place of Presentation: 名古屋
• [Presentation] Reaction of Ni^<11>-Ni^0 Dinuclear Complex and Methylcobaloxime Modeling the Function of Acetyl-CoA Synthase (2009)
  • Author(s): M. Kotera, M. Ito, Y. Song, T. Matsumoto, K. Tatsumi
  • Organizer: International Symposium on Chemistry of Reductase II
  • Place of Presentation: 名古屋
• [Presentation] Dihydrogen Activation by Dinuclear Ge-Ru Complexes Modeling [NiFe] Hydrogenase (2008)
  • Author(s): Matsumoto, T.
  • Organizer: The 2^<nd> International Symposium on Concerto Catalysis
  • Place of Presentation: 東京
• [Presentation] アセチルCoA合成酵素の活性中心モデルとなるニッケル二核錯体とコバルトメチル錯体の反応 (2008)
  • Author(s): 小寺麻衣・伊藤幹直・宋宝梅・松本剛・巽和行
  • Organizer: 第58回錯体化学討論会
  • Place of Presentation: 金沢
• [Presentation] メチル補酵素M還元酵素のモデル反応 : ニッケル(I)錯体によるC-S結合切断 (2008)
  • Author(s): 西垣潤一・松本剛・巽和行
  • Organizer: 第58回錯体化学討論会
  • Place of Presentation: 金沢
• [Presentation] コバロキシムからニッケルへのメチル移動を利用したアセチルCoA合成酵素モデル反応 (2008)
  • Author(s): 松本剛・小寺麻衣・伊藤幹直・巽和行
  • Organizer: 第102回触媒討論会
  • Place of Presentation: 名古屋
• [Presentation] ヒドロゲナーゼに学ぶゲルマニウムールテニウム複核錯体の可逆な水素活性化 (2008)
  • Author(s): 松本剛・小寺林衣・伊藤幹直・巽和行
  • Organizer: 第55回杉金属化学討論会
  • Place of Presentation: 大阪
• [Presentation] アセチルCoA合成酵素を模倣したニッケル二核錯体の酵素モデル反応 (2008)
  • Author(s): 松本剛・伊藤幹直・小寺麻衣・巽和行
  • Organizer: 第35回有機典型元素化学討論会
  • Place of Presentation: 東京
• [Presentation] Chalcogenide-Bridged Ru-Ge Dinuclear Complexes : Protonation Effects upon Structure and Reactions (2008)
  • Author(s): T. Matsumoto
  • Organizer: The 6^<th> Joint Seminar University of Munster-Nagoya University
  • Place of Presentation: 名古屋
• [Presentation] Reversible Interconversion Between H_2O and H_2 on Hetero-Bimetallic Ge-Ru Complexes : a Functional Hydrogenase Model (2008)
  • Author(s): T. Matsumoto, K. Tatsumi
  • Organizer: XXIII International Conference on Organometallic Chemistry (ICOMC 2008)
  • Place of Presentation: レンヌ(フランス)
• [Presentation] Dinuclear Ni(II)-Ni(I) Complex Modeling the Active Site of Acetyl-CoA Synthases (2008)
  • Author(s): M. Ito, M. Kotera, Y. Song, T. Matsumoto, K. Tatsumi
  • Organizer: International Symposium on Chemistry of Reductases
  • Place of Presentation: 名古屋
• [Presentation] Dicarboxyamido-dithiolato Bridged Dinuclear Nickel Complexes: Modeling the Active Site of Acetyl Coenzyme A Synthase (2008)
  • Author(s): Y. Song, M. Ito, T. Matsumoto, Kazuyuki Tatsumi
  • Organizer: International Symposium on Chemistry of Reductases
  • Place of Presentation: 名古屋
• [Presentation] アセチルCoA合成酵素の活性中心モデルとなるニッケル複核錯体とコバルトメチル錯体を用いたチオアセテート生成反応 (2008)
  • Author(s): 伊藤幹直・小寺麻衣・松本剛・巽和行
  • Organizer: 日本化学会第88春季年会
  • Place of Presentation: 東京
• [Presentation] Dinuclear Nickel Complexes Having the Diamidodithiolate Iigand: Model Complexes of the Active Site in Acetyl Coenzyme A Synthase (2008)
  • Author(s): 宋玉梅・松本剛・巽和行
  • Organizer: 日本化学会第88春季年会
  • Place of Presentation: 東京
• [Presentation] オキソ-およびスルフィド-架橋ゲルマニウム-ルテニウム錯体によるH-H σ結合活性化に関する理論的研究 (2008)
  • Author(s): 越智紀章・中尾嘉秀・佐藤啓文・松本剛・巽和行・榊茂好
  • Organizer: 日本化学会第88春季年会
  • Place of Presentation: 東京
• [Presentation] アセチルCoA合成酵素の活性中心モデル:メチル基とチオラートを持つニッケル二核錯体の合成と反応 (2008)
  • Author(s): 小寺麻衣・伊藤幹直・松本剛・巽和行
  • Organizer: 日本化学会第88春季年会
  • Place of Presentation: 東京
• [Presentation] Dinuclear Nickel Complexes Having the Diamidodithiolate ligand: Model Complexes of the Active Site in Acetyl Coenzyme A Synthase (2008)
  • Author(s): 宋玉梅・松本剛・巽和行
  • Organizer: 日本化学会第88春季年会
  • Place of Presentation: 東京
• [Presentation] オキソ-およびスルフィド-架橋ゲルマニウムールテニウム錯体によるH-Hσ結合活性化に関する理論的研究 (2008)
  • Author(s): 越智紀章・中尾嘉秀・佐藤啓文・松本剛・巽和行・榊茂好
  • Organizer: 日本化学会第88春季年会
  • Place of Presentation: 東京
• [Presentation] Dihydrogen Activation by Chalcogenide-bridged Bimetallic Ru-Ge Complexes (2007)
  • Author(s): Matsumoto, T.
  • Organizer: 第1回アジア国際シンポジウム
  • Place of Presentation: 大阪
  • Year and Date: 2007-03-27
• [Presentation] ヒドロゲナーゼに学ぶゲルマニウムールテニウム複核錯体の可逆な水素活性化 (2007)
  • Author(s): 松本剛
  • Organizer: 東京工業大学理学研究流動機構シンポジウム"元素の個性-どう見るか、どうつくるか、どう使うか-
  • Place of Presentation: 東京
• [Presentation] Dinuclear Nickel Complexes modeling Acetyl-CoA Synthase (2007)
  • Author(s): Matsumoto, T.
  • Organizer: The 13th International Conference on Bioinorganic Chemistry (ICBIC 13)
  • Place of Presentation: ウイーン、オーストリア
• [Presentation] ヒドロゲナーゼに学ぶゲルマニウムールテニウム複核錯体の可逆な水素活性化 (2007)
  • Author(s): Y. Song, M. Ito, T. Matsumoto, Kazuyuki Tatsumi
  • Organizer: 東工大理学研究流動機構シンポジウム"元素の個性-どう見るか、どうつくるか、どう使うか-
  • Place of Presentation: 東京
• [Presentation] Dinuclear Nickel Complexes Modeling the Active Site of Acetyl-CoA Synthases (2007)
  • Author(s): M. Ito, M. Kotera, Y. Song, T. Matsumoto, K. Tatsumi
  • Organizer: Workshop on Bioinorganic and Organometallic Perspectives in Activation of Small Molecules
  • Place of Presentation: 岡崎
• [Presentation] Dihydrogen Activation by Hetero-dinuclear Ru/Ge Complexes: A Hydrogenase Model (2007)
  • Author(s): T. Matsumoto, K. Tatsumi
  • Organizer: Workshop on Bioinorganic and Organometallic Perspectives in Activation of Small Molecules
  • Place of Presentation: 岡崎
• [Presentation] Dinuclear Nickel Complexes modeling Acetyl-CoA Synthase (2007)
  • Author(s): T. Matsumoto, M. Ito, K. Tatsumi
  • Organizer: The 13th International Conference on Bioinorganic Chemistry (ICBIC 13)
  • Place of Presentation: オーストリア、ウイーン
• [Presentation] かさ高いゲルマンチオラートを配位子とするニッケル錯体 (2007)
  • Author(s): 松本剛・巽和行
  • Organizer: 第57回錯体化学討論会
  • Place of Presentation: 名古屋
• [Presentation] アセチルCoA合成酵素活性中心のモデルとなるNi(II)-Ni(0)およびNi(II)-Ni(I)複核錯体 (2007)
  • Author(s): 伊藤幹直・小寺麻衣・宋玉梅・松本剛・巽和行
  • Organizer: 第57回錯体化学討論会
  • Place of Presentation: 名古屋
• [Presentation] 古くて新しい還元系金属酵素-生物無機化学の新展開 (2007)
  • Author(s): 巽和行・大木靖弘・松本剛
  • Organizer: 第57回錯体化学討論会
  • Place of Presentation: 名古屋
• [Presentation] H_2の活性化 (2006)
  • Author(s): 松本剛
  • Organizer: 第56回錯体化学討論会シンポジウム"小分子の活性化新展開"
  • Place of Presentation: 広島
• [Presentation] Enzymatic Reaction Models of [NiFe] Hydrogenase and Acetyl-CoA Synthase (2006)
  • Author(s): Matsumoto, T.
  • Organizer: International COE Symposium for Young Scientists on Frontiers of Molecular Science
  • Place of Presentation: 東京
• [Remarks] Dalton Trans 2010, 12号の中表紙
• [Remarks] Angew. Chem. Int. Ed. 2006, 23号の口絵(Frontispiece)
• [Remarks]
  • URL: http://inorg.chem.nagoya-u.ac.jp
• [Remarks]
  • URL: http://inorg.chem.nagoya-u.ac.jp