| Budget Amount *help |
¥112,060,000 (Direct Cost: ¥86,200,000、Indirect Cost: ¥25,860,000)
Fiscal Year 2010: ¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2009: ¥22,100,000 (Direct Cost: ¥17,000,000、Indirect Cost: ¥5,100,000)
Fiscal Year 2008: ¥22,100,000 (Direct Cost: ¥17,000,000、Indirect Cost: ¥5,100,000)
Fiscal Year 2007: ¥22,100,000 (Direct Cost: ¥17,000,000、Indirect Cost: ¥5,100,000)
Fiscal Year 2006: ¥26,910,000 (Direct Cost: ¥20,700,000、Indirect Cost: ¥6,210,000)
|
|---|
| Research Abstract |
Koji mold(Aspergillus oryzae) has been used for sake, soy sauce, and miso and is one of the most important microorganisms in Japan. A. oryzae has an ability of secreting a large amount of useful protein like enzymes. Protein secretion process in A. oryzae cell was precisely elucidated by molecular and cellular biological methods using the whole genome sequence information that was recently completed. Based on the results obtained above, koji mold strains producing a large amount of useful protein were successfully bred by gene disruption and mutant isolation.
|
