Representation of time in the brain

• Project/Area Number: 18200024
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Neuroscience in general
• Research Institution: Juntendo University
• Principal Investigator: KITAZAWA Shigeru Juntendo University, 医学部, 教授 (00251231)
• Co-Investigator(Kenkyū-buntansha): KANSAKU Kenji 国立身体障害者リハビリテーションセンター(研究所), 感覚機能系障害研究部, 室長 (60399318) ; TAKAHASHI Toshimitsu 順天堂大学, 医学部, 助教 (00250704) ; WADA Makoto 順天堂大学, 医学部, 助教 (20407331)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥47,190,000 (Direct Cost: ¥36,300,000、Indirect Cost: ¥10,890,000); Fiscal Year 2008: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000); Fiscal Year 2007: ¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000); Fiscal Year 2006: ¥28,600,000 (Direct Cost: ¥22,000,000、Indirect Cost: ¥6,600,000)
• Keywords: 認知神経科学 / fMRI / 経頭蓋磁気刺激(TMS) / 時間順序判断 / 脳波 / ベイズ推定 / ラグアダプテーション / 体性感覚 / サッケード / ヒト / TMS / 異種感覚信号 / MEG

Research Abstract

脳は信号の時間順序をどのようにして決定しているのだろうか。左右の手に刺激を加えて時間順序を回答させる課題で、手を交差すると時間順序判断が逆転するという現象を手がかりをしてこの問題に取り組んだ。非侵襲脳活動計測と経頭蓋磁気刺激法を組み合わせた研究を行った結果、脳は信号の空間位置の情報と「動き」の情報を統合して時間順序を再構成しているという仮説(動き投影仮説)を支持する結果を得た。

Research Products

• [Journal Article] The effect of marker size on the perception of an empty interval (2009)
  • Author(s): Ono, F., & Kitazawa, S
  • Journal Title: Psychonomic Bulletin & Review 16 Pages: 182-189
• [Journal Article] The effect of marker size on the perception of an empty interval. (2009)
  • Author(s): Ono, F., Kitazawa, S.
  • Journal Title: Psychonomic Bulletin & Review 16 Pages: 182-189
  • Peer Reviewed
• [Journal Article] Neuronal activity related toanticipated and elapsed time in macaque supplementary eye field (2008)
  • Author(s): Ohmae S, Lu X, Takahashi T, Uchida Y, and Kitazawa S
  • Journal Title: Exp Brain Res 184 Pages: 593-598
• [Journal Article] Neural correlates involved in processing happy affect on same race faces (2008)
  • Author(s): Iidaka, T., Nogawa, J., Kansaku, K., Sadato, N
  • Journal Title: Journal of Psychophysiology 2(2) Pages: 91-99
  • Peer Reviewed
• [Journal Article] Neuronal activity related to anticipated and elapsed time in macaquesupplementary eye field (2008)
  • Author(s): Ohmae S, Lu X, Uchida Y, Takahashi T, Kitazawa S.
  • Journal Title: Experimental Brain Research 184・4 Pages: 593-598
  • Peer Reviewed
• [Journal Article] Referral of tactile stimuli to action points invirtual reality with reaction force (2007)
  • Author(s): Moizumi S, Yamamoto S, and Kitazawa S
  • Journal Title: Neurosci Res 59 Pages: 60-67
• [Journal Article] Effects of visual stimuli on temporal order judgments of unimanual finger stimuli (2007)
  • Author(s): Shibuya S, Takahashi T, and Kitazawa S
  • Journal Title: Exp Brain Res 179 Pages: 709-721
• [Journal Article] Effects of visual stimuli on temporal order judgments of unimanual finger stimuli (2007)
  • Author(s): Shibuya, S., Takahashi, T., Kitazawa, S.
  • Journal Title: Experimental Brain Research 179・4 Pages: 709-721
  • Peer Reviewed
• [Journal Article] Referral of tactile stimuli to action points in virtual reality with reaction force (2007)
  • Author(s): Moizumi, S., Yamamoto, S., Kitazawa, S.
  • Journal Title: Neuroscience Research 59・1 Pages: 60-67
  • NAID: 10024416814
  • Peer Reviewed
• [Journal Article] The role of the human ventral premotor cortex in counting successive stimuli (2007)
  • Author(s): Kansaku, K., Carver, B., Johnson, A., Matsuda, K., Sadato, N., Hallett, M.
  • Journal Title: Neuroscience Research 59・1 Pages: 60-67
  • Peer Reviewed
• [Journal Article] Effects of visual stimuli on temporal order judgments of unimanual finger stimuli (2007)
  • Author(s): Shibuya, S., Takahashi, T., Kitazawa, S.
  • Journal Title: Experimental Brain Research (in press)
• [Journal Article] The role of the human ventral premotor cortex in counting successive stimuli (2006)
  • Author(s): Kansaku, K., Carver, B., Johnson, A., Matsuda, K., Sadato, N., Hallett, M
  • Journal Title: Exp Brain Res 178 Pages: 339-350
• [Journal Article] Bayesian calibration of simultaneity in tactile temporal order judgment (2006)
  • Author(s): Miyazaki, M., Yamamoto, S., Uchida, S. & Kitazawa, S
  • Journal Title: Nat Neurosci 9 Pages: 875-7
• [Journal Article] Neuralcorrelates of counting of sequential sensory and motor events in the human brain (2006)
  • Author(s): Kansaku, K., Johnson, A., Grillon, M. L., Garraux, G., Sadato, N., Hallett, M.
  • Journal Title: Neuro Image 31 Pages: 649-660
• [Journal Article] Bayesian calibration of simultaneity in tactile temporal order judgment (2006)
  • Author(s): Miyazaki, M., Yamamoto, S., Uchida, S., Kitazawa, S.
  • Journal Title: Nature Neuroscience 9・7 Pages: 875-877
• [Journal Article] Statistical parametric mapping of immunopositive cell density (2006)
  • Author(s): Wada, M., Yoshimi, K., Higo, N., Rem, Y.R., Mochizuki, H., Mizuno, Y., Kitazawa, S.
  • Journal Title: Neuroscience Research 56 Pages: 96-102
  • NAID: 10018772110
• [Journal Article] Neural correlates of counting of sequential sensory and motor events in the human brain. (2006)
  • Author(s): Kansaku, K., Johnson, A., Grillon, M.L., Garraux, G., Sadato, N., Hallett, M.
  • Journal Title: Neurolmage 31(2) Pages: 649-660
• [Journal Article] The role of the human ventral premotor cortex in counting succesive stimuli.
  • Author(s): Kansaku, K., Carver, B., Johnson, A., Matsuda, K., Sadato, N., Hallett, M.
  • Journal Title: Experimental Brain Research (in press)
• [Presentation] Representation of exact abstract concepts in the human brain (2009)
  • Author(s): Kansaku. K
  • Organizer: The 3rd Japanese-French Frontiers of Science Symposium
  • Place of Presentation: Shonan, Japan
  • Year and Date: 2009-01-24
• [Presentation] Temporo-spatial gaze patterns in autisticchildren 38th Annual Meeting (2008)
  • Author(s): Kitazawa S, Endo Y, Yamane M, Takahashi M
  • Organizer: Society for Neuroscience
  • Place of Presentation: Washington
  • Year and Date: 2008-11-17
• [Presentation] Synchronization changes during action execution and observation : a whole-head MEG study (2008)
  • Author(s): Komatsu, T., Sakihara, K., Gjini, K., Nakajima, Y., Kansaku. K
  • Organizer: The 38th Annual Meeting of the Society for Neuroscience
  • Place of Presentation: Washington DC, USA
  • Year and Date: 2008-11-17
• [Presentation] 時間順序の知覚の脳内メカニズム (2008)
  • Author(s): 北澤茂.
  • Organizer: 第6回知と行動研究シンポジウム「知と行動研究のストラテジーVI」
  • Place of Presentation: 大阪箕面
  • Year and Date: 2008-11-06
• [Presentation] 時間順序の知覚の脳内メカニズム (2008)
  • Author(s): 北澤 茂
  • Organizer: 第6回知と行動研究シンポジウム「知と行動研究のストラテジーVI」
  • Place of Presentation: 箕面, 大阪
  • Year and Date: 2008-11-06
• [Presentation] 触知覚メカニズムを考える (2008)
  • Author(s): 北澤茂
  • Organizer: 日本心理学会第72回大会ワークショップ身体と感覚の結びつき-ラバーハンドイリュージョンと幻肢-
  • Place of Presentation: 北海道大学、札幌
  • Year and Date: 2008-09-20
• [Presentation] 時間知覚の様々な例外 (2008)
  • Author(s): 北澤 茂
  • Organizer: 日本心理学会第72回大会シンポジウム 心と脳のなかの時間〜感覚・知覚における時間の問題
  • Place of Presentation: 北海道大学, 札幌
  • Year and Date: 2008-09-20
• [Presentation] 触知覚メカニズムを考える (2008)
  • Author(s): 北澤 茂
  • Organizer: 日本心理学会第72回大会ワークショップ身体と感覚の結びつき-ラバーハンドイリュージョンと幻肢-
  • Place of Presentation: 北海道大学, 札幌
  • Year and Date: 2008-09-20
• [Presentation] 時間知覚の様々な例外 (2008)
  • Author(s): 北澤茂
  • Organizer: 日本心理学会第72回大会シンポジウム心と脳のなかの時間~感覚・知覚における時間の問題
  • Place of Presentation: 北海道大学、札幌
  • Year and Date: 2008-09-19
• [Presentation] Effects of visual cues on acquisition of multiple prior distributions in tactile tem poral order judgments. (2008)
  • Author(s): Nagai, Y. Suzuki, M., Miyazaki, M. & Kitazawa S.
  • Organizer: International Mutisensory Research Forum
  • Place of Presentation: Hamburg, Germany
  • Year and Date: 2008-07-19
• [Presentation] Bayesian calibration of simultaneity in audiovisual temporal order judgment. (2008)
  • Author(s): Yamamoto, S., Miyazaki, M., Iwano, T., Masuda, T. & Kitazawa, S.
  • Organizer: International Mutisensory Research Forum
  • Place of Presentation: Hamburg, Germany
  • Year and Date: 2008-07-19
• [Presentation] Adaptive anomalies in conscious time perception. (2008)
  • Author(s): Kitazawa s. & Nishida s.
  • Organizer: Tutorial workshop in the 12th Annual Meeting of the Association for the Scientific Study of Consciousness.
  • Place of Presentation: Taipei, Taiwan
  • Year and Date: 2008-06-20
• [Presentation] Limits and possibilities of neuroimaging approach to behavior in society : the case of sex differences in language function in the human brain (2008)
  • Author(s): Kansaku, K
  • Organizer: Todai-Yale Initiative Symposuim on Mind, Brain, and Society : Neurocognitive Approaches to the Social Scien ces
  • Place of Presentation: New Haven, CT, USA
  • Year and Date: 2008-04-25
• [Presentation] 脳の中の時間:腕の交差や目の動きで逆転する時間 (2008)
  • Author(s): 北澤 茂
  • Organizer: 日本生理学会若手の会サイエンスカフェ
  • Place of Presentation: 青山、東京
  • Year and Date: 2008-03-26
• [Presentation] 脳の中の時間 : 腕の交差や目の動きで逆転する時間 (2008)
  • Author(s): 北澤茂
  • Organizer: 第5回自然科学研究機構シンポジウム
  • Place of Presentation: 東京国際フォーラム、東京
  • Year and Date: 2008-03-20
• [Presentation] 脳の中の時間 (2008)
  • Author(s): 北澤 茂
  • Organizer: 第5回自然科学研究機構シンポジウム
  • Place of Presentation: 東京国際フォーラムホール、日本
  • Year and Date: 2008-03-20
• [Presentation] 脳の中の時間~分散した情報からの再構成~ (2008)
  • Author(s): 北澤茂
  • Organizer: 第20回自律分散システムシンポジウム
  • Place of Presentation: 上諏訪
  • Year and Date: 2008-01-24
• [Presentation] 脳の中の時間〜分散した情報からの再構成 (2008)
  • Author(s): 北澤 茂
  • Organizer: 第20回自律分散システムシンポジウム
  • Place of Presentation: 諏訪、日本
  • Year and Date: 2008-01-24
• [Presentation] Adaptive anomalies in conscious time perception (2008)
  • Author(s): Kitazawa S. & Nishida S
  • Organizer: Tutorial workshop in the 12th Annual Meeting of the Association for the Scientific Study of Consciousness
  • Place of Presentation: Taipei, Taiwan
• [Presentation] Reversal of subjective temporal order due to eye and handmovements (2007)
  • Author(s): Kitazawa, S
  • Organizer: ESF-EMBO symposia on "Three-Dimensional Sensory and Motor Space"
  • Place of Presentation: Sant Feliu de Guixols, Spain
  • Year and Date: 2007-10-10
• [Presentation] Reversal of subjective temporal order due to eye and hand movements (2007)
  • Author(s): Kitazawa, S.
  • Organizer: ESF-EMBO symposia on"Three-Dimensional Sensory and Motor Space"
  • Place of Presentation: スペイン・Sant Fehu deGuixols
  • Year and Date: 2007-10-10
• [Presentation] Eye-position dependent acquisition of multiple prior distributions in tactile temporal order judgments (2007)
  • Author(s): Y Nagai, M Suzuki, M Miyazaki, S Kitazawa
  • Organizer: ESF-EMBO symposia on"Three-Dimensional Sensory and Motor Space"
  • Place of Presentation: スペイン・Sant Fehu deGuixols
  • Year and Date: 2007-10-10
• [Presentation] 脳内の時間順序認識と脳内座標 (2007)
  • Author(s): 北澤茂
  • Organizer: 認識と運動における主体性の数理脳科学2007年度第1回研究会
  • Place of Presentation: 国際高等研究所、京都
  • Year and Date: 2007-09-22
• [Presentation] 脳内の時間順序認識と脳内座標 (2007)
  • Author(s): 北澤 茂
  • Organizer: 認識と運動における主体性の数理脳科学2007年度第1回研究会
  • Place of Presentation: 国際高等研究所、京都、日本
  • Year and Date: 2007-09-22
• [Presentation] 触覚はいつどこで生まれるのか (2007)
  • Author(s): 北澤茂
  • Organizer: 「第4回人間総合科学会学術集会」特別講演
  • Place of Presentation: 東京
  • Year and Date: 2007-02-17
• [Presentation] 脳の中の時間 (2007)
  • Author(s): 北澤茂
  • Organizer: 情報処理学会第122回ヒューマンインターフェース研究会特別講演
  • Place of Presentation: 伊豆長岡
  • Year and Date: 2007-02-09
• [Presentation] 触覚の生じる場所~時間順序判断からの示唆~ (2006)
  • Author(s): 北澤茂
  • Organizer: The Trans-disciplinary symposium on the frontier of mind-brain science and its practical applications (III) -Toward the science of KANSEI
  • Place of Presentation: 日立基礎研究所、東京
  • Year and Date: 2006-11-24
• [Presentation] 時間順序判断における異種感覚の統合 (2006)
  • Author(s): 北澤茂
  • Organizer: 日本心理学会第70回大会ワークショップ
  • Place of Presentation: 福岡
  • Year and Date: 2006-11-03
• [Presentation] Where tactile signals are ordered intime (2006)
  • Author(s): 北澤茂
  • Organizer: 第29回日本神経科学大会シンポジウム
  • Place of Presentation: 京都
  • Year and Date: 2006-07-20
• [Presentation] Reversal of subjective temporal order due to sensory and motor integrations (2006)
  • Author(s): Kitazawa, S
  • Organizer: Attention and Performance XXII. Sensorimotor foundations of higher cognition
  • Place of Presentation: Chateau de Pizay, France
• [Book] Biomagnetism : Interdisciplinary Research and Exploration (2008)
  • Author(s): Gjini, K., Sakihara, K., Ueno, S., Ando, J., Kansaku. K
  • Publisher: Hokkaido University Press
• [Book] In : Sensorimotor Foundations of Higher Cognition (Attention and Performance XXII), edited by Haggard P, Kawato M, and Rossetti Y, Oxford Univ Press (2007)
  • Author(s): Kitazawa S, Moizumi S, Okuzumi A, Saito F, Shibuya S, Takahashi T, Wada M, and Yamamoto S.
  • Publisher: Reversal of subjective temporal order due to sensory and motor integrations
• [Book] Reversal of subj ective temporal order due to sensory and motor integrations.In:Attention&Performance XXIII edited by Haggard P, Kawato M, and Rossetti Y. (2007)
  • Author(s): Kitazawa S, Moizumi S, Okuzumi A, Saito F, Shibuya S, Takahashi T, Wada M, Yamamoto S.
  • Publisher: Oxford University Press
• [Remarks] 「脳が順序を錯覚」日経新聞2006年5月29日朝刊
• [Remarks] 「脳の時間順序判断の仕組み」科学新聞2006年9月29日