| Budget Amount *help |
¥49,140,000 (Direct Cost: ¥37,800,000、Indirect Cost: ¥11,340,000)
Fiscal Year 2009: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
Fiscal Year 2008: ¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
Fiscal Year 2007: ¥12,090,000 (Direct Cost: ¥9,300,000、Indirect Cost: ¥2,790,000)
Fiscal Year 2006: ¥14,430,000 (Direct Cost: ¥11,100,000、Indirect Cost: ¥3,330,000)
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| Research Abstract |
A new scientific research field "time-resolved thermodynamics" was created so that two important fields, the thermodynamics and the dynamics, are unified. This new technique was applied to researches of reaction mechanism of biological proteins and various thermodynamical properties, i.e., enthalpy, partial molar volume, heat capacity change and so on, have been measured in time domain for the first time. Many spectrally silent dynamics of protein reactions were elucidated and reaction mechanisms in molecular level have been established.
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