Catalytic Construction of Carbon Skeletons Based on the Generation of Carbene Complexes from Hydrocarbons

• Project/Area Number: 18205006
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Organic chemistry
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: IWASAWA Nobuharu Tokyo Institute of Technology, 大学院・理工学研究科, 教授 (40168563)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥48,880,000 (Direct Cost: ¥37,600,000、Indirect Cost: ¥11,280,000); Fiscal Year 2008: ¥14,170,000 (Direct Cost: ¥10,900,000、Indirect Cost: ¥3,270,000); Fiscal Year 2007: ¥13,910,000 (Direct Cost: ¥10,700,000、Indirect Cost: ¥3,210,000); Fiscal Year 2006: ¥20,800,000 (Direct Cost: ¥16,000,000、Indirect Cost: ¥4,800,000)
• Keywords: カルベン錯体 / 炭素骨格構築 / 遷移金属触媒 / アルキンの求電子的活性化 / 1,3-双極子 / ビシクロ[5.3.0]デカン誘導体 / カチオン性白金錯体 / 白金含有カルボニルイリド / 鎖状γ,δ-イノン / アルキン類の求電子的活性化 / 8-オキサビシクロ[3.2.1]オクタン誘導体 / 三環性インドール誘導体 / 分子間[3+2]付加環化反応 / タングステンカルベン錯体 / ジエノールシリルエーテル / オキサビシクロ〔3.2.1〕オクタン / 白金カルベン錯体 / タングステン含有アンモニウムイリド / 多置換インドール / アレン / タングステンカルボニル / ビシクロ[5.3,0]オクタン骨格 / 塩化白金 / シクロペンタジエン / 炭素-水素結合挿入反応

Research Abstract

アルケン、アルキン等の炭化水素類と適切な遷移金属錯体から簡便かつ一般性良くカルベン錯体を生成させる新手法の開発、ならびに生成したカルベン錯体を利用し、その特徴を生かした触媒的炭素骨格構築反応の実現を目的に研究を行った。その結果、合成中間体として有用な各種の炭素環状化合物を比較的単純な化合物から効率よく合成するさまざまな手法を開発することに成功した。

Research Products

• [Journal Article] Gold-Catalyzed Tandem Cyclization of Dienol-Silyl Ethers for the Preparation of Bicyclo[4. 3. 0]nonane Derivatives (2010)
  • Author(s): H. Kusama, Y. Karibe, Y. Onizawa, N. Iwasawa
  • Journal Title: Angew. Chem. Int. Ed. 49(on line) Pages: 4269-4272
  • Peer Reviewed
• [Journal Article] Rhenium(I)-Catalyzed Cyclization of Silyl Enol Ethers Containing a Propargyl Carboxylate Moiety : A Versatile Access to Highly Substituted Phenols (2010)
  • Author(s): K. Saito, Y. Onizawa, H. Kusama, N. Iwasawa
  • Journal Title: Chem. Eur. J. 16 Pages: 4716-4720
  • Peer Reviewed
• [Journal Article] Rhenium(I)-Catalyzed Cyclization of Silyl Enol Ethers Containing a Propargyl Carboxylate Moiety : A Versatile Access to Highly Substituted Phenols (2010)
  • Author(s): K.Saito, Y.Onizawa, H.Kusama, N.Iwasawa
  • Journal Title: Chem.Eur.J. 16(In press)
  • Peer Reviewed
• [Journal Article] Gold-Catalyzed Tandem Cyclization of Dienol-Silyl Ethers for the Preparation of Bicyclo[4.3.0]nonane Derivatives (2010)
  • Author(s): H.Kusama, Y.Karibe, Y.Onizawa, N.Iwasawa
  • Journal Title: Angew.Chem.Int.Ed. 49(In press)
  • Peer Reviewed
• [Journal Article] Platinum(II)-Catalyzed Intermolecular [3+2]-Cycloaddition of Propadienyl Silyl Ethers and Alkenyl Ethers (2009)
  • Author(s): H. Kusama, M. Ebisawa, H. Funami, N. Iwasawa
  • Journal Title: J. Am. Chem. Soc. 131 Pages: 16352-16353
  • Peer Reviewed
• [Journal Article] Theoretical Study on the Cycloaddition Reaction of a Tungsten-Containing Carbonyl Ylide (2009)
  • Author(s): K. Ito, Y. Hara, S. Mori, H. Kusama, N. Iwasawa
  • Journal Title: Chem. Eur. J. 15 Pages: 12408-12416
  • NAID: 130004644996
  • Peer Reviewed
• [Journal Article] Theoretical Study on the Cycloaddition Reaction of a Tungsten-Containing Carbonyl Ylide (2009)
  • Author(s): K.Ito, Y.Hara, S.Mori, H.Kusama, N.Iwasawa
  • Journal Title: Chem.Eur.J. 15 Pages: 12408-12416
  • NAID: 130004644996
  • Peer Reviewed
• [Journal Article] Molybdenum(0)-Promoted Carbonylative Cyclization of o-Haloaryl-and β-Haloalkenylimine Derivatives via Oxidative Addition of sp^2 Carbon-Halogen Bond : Preparation of Two Types of γ-Lactam Derivatives (2009)
  • Author(s): J.Takaya, K.Sangu, N.Iwasawa
  • Journal Title: Angew.Chem.Int.Ed. 48 Pages: 7090-7093
  • Peer Reviewed
• [Journal Article] Rhodium(I)-Catalyzed [4+1] Cycloaddition Reactions of α, β-Unsaturated Imines with Terminal Alkynes for the Preparation of Substituted Pyrroles (2009)
  • Author(s): A.Mizuno, H.Kusama, N.Iwasawa
  • Journal Title: Angew.Chem.Int.Ed. 48 Pages: 8318-8320
  • Peer Reviewed
• [Journal Article] Platinum(II)-Catalyzed Intermolecular [3+2]-Cycloaddition of Propadienyl Silyl Ethers and Alkenyl Ethers (2009)
  • Author(s): H.Kusama, M.Ebisawa, H.Funami, N.Iwasawa
  • Journal Title: J.Am.Chem.Soc. 131 Pages: 16352-16353
  • Peer Reviewed
• [Journal Article] New Route to N-fused Tricyclic Indoles via Tandem [1, 2]-Stevens-type Rearrangement/1, 2-Alkyl Migration of Metal-Containing Ammonium Ylide (2008)
  • Author(s): J. Takaya, S. Udagawa, H. Kusama, N. Iwasawa
  • Journal Title: Angew. Chem. Int. Ed. 47 Pages: 4906-4909
  • Peer Reviewed
• [Journal Article] Platinum(II)-Catalyzed Reaction ofγ, δ-Ynones with Alkenes for the Construction of 8-Oxabicyclo[3. 2. 1]octane Skeletons: Generation of Platinum-Containing Carbonyl Ylides from Acyclic Precursors (2008)
  • Author(s): H. Kusama, K. Ishida, H. Funami, N. Iwasawa
  • Journal Title: Angew. Chem. Int. Ed. 47 Pages: 4903-4905
  • Peer Reviewed
• [Journal Article] Efficient Control ofπ-Alkyne and Vinylidene Complex Pathways for the W(CO)5(L)-Catalyzed Synthesis of Two Types of Nitrogen-Containing Bicyclic Compounds (2008)
  • Author(s): Y. Onizawa, H. Kusama, N. Iwasawa
  • Journal Title: J. Am. Chem. Soc. 130 Pages: 802-803
  • Peer Reviewed
• [Journal Article] Synthesis, Structure, and Reactivity of Naphthalyne-C_<o2>(CO)_6 Complexes (2008)
  • Author(s): N.Iwasawa, M.Otsuka, S.Yamashita, M.Aoki, J.Takaya
  • Journal Title: J.Am.Chem.Soc. 130 Pages: 6328-6329
  • Peer Reviewed
• [Journal Article] Platinum(II)-Catalyzed Reaction of γ, δ-Ynones with Alkenes for the Construction of 8-Oxabicyclo[3.2.1]octane Skeletons : Generation of Platinum-Containing Carbonyl Ylides from Acyclic Precursors (2008)
  • Author(s): H.Kusama, K.Ishida, H.Funami, N.Iwasawa
  • Journal Title: Angew.Chem.Int.Ed. 47 Pages: 4903-4905
  • Peer Reviewed
• [Journal Article] New Route to N-fused Tricyclic Indoles via Tandem[1, 2]-Stevens-type Rearrangement/1, 2 -Alkyl Migration of Metal-Containing Ammonium Ylide (2008)
  • Author(s): J.Takaya, S.Udagawa, H.Kusama, N.Iwasawa
  • Journal Title: Angew.Chem.Int.Ed. 47 Pages: 4906-4909
  • Peer Reviewed
• [Journal Article] Platinum(II)-Catalyzed Reaction of γ,δ-Ynones with Alkenes for the Construction of 8-Oxabicyclo[3.2.1]octane Skeletons:Generation of Platinum-Containing Carbonyl Ylides from Acyclic Precursors (2008)
  • Author(s): H.Kusama, K. Ishida, H. Funami, N. Iwasawa
  • Journal Title: Angewandte Chemie International Edition 47(In press)
  • Peer Reviewed
• [Journal Article] New Route to N-fused Tricyclic Indoles via Tandem[1,2]-Stevens-type Rearrangement/1,2-Alkyl Migration of Metal-Containing Ammonium Ylide (2008)
  • Author(s): J. Takaya, S. Udagawa, H. Kusama, N. Iwasawa
  • Journal Title: Angewandte Chemie International Edition 47(In press)
  • Peer Reviewed
• [Journal Article] Synthesis, Structure, and Reactivity of Naphthalyne-Co_2(CO)_6 Complexes (2008)
  • Author(s): N. Iwasawa, M. Otsuka, S. Yamashita, M. Aoki, J. Takaya
  • Journal Title: Journal of the American Chemical Society 130(In press)
  • Peer Reviewed
• [Journal Article] Efficient Control of π-Alkyne and Vinylidene Complex Pathways for the W(CO)_5(L)-Catalyzed Synthesis of Two Types of Nitrogen-Containing Bicyclic Compounds (2008)
  • Author(s): Y. Onizawa, H. Kusama, N. Iwasawa
  • Journal Title: Journal of the American Chemical Society 130 Pages: 802-803
  • Peer Reviewed
• [Journal Article] Preparation of Substituted Cyclopentadienes through Platinum(II)-Catalyzed Cyclization of 1, 2, 4-Trienes: the Presence of Platinum-Carbene Complex Intermediate (2007)
  • Author(s): H. Funami, H. Kusama N. Iwasawa
  • Journal Title: Angew. Chem. Int. Ed. 46 Pages: 909-911
  • Peer Reviewed
• [Journal Article] Synthesis of Naphthalene Derivatives through Platinum(II)-Catalyzed Reaction of 2-Alkynylbenzoates with Vinyl Ethers (2007)
  • Author(s): H. Kusama, H. Funami, N. Iwasawa
  • Journal Title: Synthesis Pages: 2014-2024
  • Peer Reviewed
• [Journal Article] Intermolecular Addition Reaction to Alkenes of Acylmolybdenum Complexes Generated by Oxidative Addition of Aryl or Alkenyl Halides with Molybdenum(0) Carbonyl Complexes (2007)
  • Author(s): K. Sangu, T. Watanabe, J. Takaya, N. Iwasawa
  • Journal Title: Synlett Pages: 929-933
  • Peer Reviewed
• [Journal Article] Stereoselective Synthesis of Medium-sized Cyclic Compounds through the Intramolecular Michael-type Reaction Utilizing Alkyne-Hexacarbonyldicobalt Complex Formation (2007)
  • Author(s): K. Inaba, J. Takaya, N. Iwasawa
  • Journal Title: Chemistry Letters 36 Pages: 474-475
  • NAID: 10018830295
  • Peer Reviewed
• [Journal Article] Preparation of Substituted Cyclopentadienes through Platinum(II)-Catalyzed Cyclization of 1,2,4-Trienes (2007)
  • Author(s): H. Funami, H. Kusama, N. Iwasawa
  • Journal Title: Angewandte Chemie International Edition 46 Pages: 909-911
  • Peer Reviewed
• [Journal Article] W(CO)_5(L)-Catalyzed Cyclization of ω-Acetylenic Silyl Enol Ethers for the Preparation of Nitrogen-Containing Cyclic Compounds (2007)
  • Author(s): A. Grandmarre, H. Kusama, N. Iwasawa
  • Journal Title: Chemistry Letters 36 Pages: 66-67
  • NAID: 10018662932
  • Peer Reviewed
• [Journal Article] W(CO)_5(L)-catalyzed 6-Endo-selective Cyclization and Formal Cope Rearrangement of Allenyl Silyl Enol Ethers (2007)
  • Author(s): T. Miura, K. Kiyota, H. Kusama, N. Iwasawa
  • Journal Title: Journal of Organometallic Chemistry 692 Pages: 562-568
  • Peer Reviewed
• [Journal Article] Preparation of Substituled Cyclopentadienes through Platinum(II)-Catalyzed Cyclization of 1,2,4-Triens; the Presence of Platinum-Crbene Complex Intermediate (2007)
  • Author(s): H.Funami, H.Kusama, N.Iwasawa
  • Journal Title: Angew.Chem.Int.Ed. 46 Pages: 909-911
• [Journal Article] W(CO)_5(L)-Catalyzed Cycilization of ω-Acetylenic Silyl Enol Ethers for the Preparation of Nitrogen-Containing Cyclic Compounds (2007)
  • Author(s): A.Grandmarre, H.Kusawa, N.Iwasawa
  • Journal Title: Chem.Lett. 36 Pages: 66-67
• [Journal Article] W(CO)_5(L)-catalyzed 6-endo-selective cyclization and formal Coperearrangement of allenyl silyl enol ethers (2007)
  • Author(s): T.Miura, K.Kiyota, H.Kusam, N.Iwasawa
  • Journal Title: J.Organoment.Chem. 692 Pages: 562-568
• [Journal Article] W(CO)5(L)-Catalyzed Tandem Intramolecular Cyclopropanation / Cope Rearrangement for the Stereoselective Construction of Bicyclo[5. 3. 0]decane Framework (2006)
  • Author(s): H. Kusama, Y. Onizawa, N. Iwasawa
  • Journal Title: J. Am. Chem. Soc. 128 Pages: 6500-16501
  • Peer Reviewed
• [Journal Article] Synthesis of Isochromene Esters Utilizing 1, 6-Addition of Nucleophiles to Benzopyranylidenetungsten(0) Complexes (2006)
  • Author(s): H. Kusama, T. Sawada, A. Okita, F. Shiozawa, N. Iwasawa
  • Journal Title: Org. Lett. 8 Pages: 1077-1079
  • Peer Reviewed
• [Journal Article] Intermolecular 1, 5-Dipolar Cycloaddition Reaction of Tungsten-Containing Vinyl-azomethine Ylides Leading to Seven-Membered Heterocycles (2006)
  • Author(s): H. Kusama, Y. Suzuki, J. Takaya, N. Iwasawa
  • Journal Title: Org. Lett. 8 Pages: 895-897
  • Peer Reviewed
• [Journal Article] Intermolecular 1,5-Dipolar Cycloaddition Reaction of Tungsten-Containing Vinyl-azomethine Ylides Leading to Seven-Membered Heterocycles (2006)
  • Author(s): H.Kusama, Y.Suzuki.J.Takaya, N.iwasawa
  • Journal Title: Org. Lett. 8 Pages: 895-897
• [Journal Article] Useful Reactions of Silylated Propargyltungsten or Progargylmolybdenum Species (2006)
  • Author(s): T.Asakura, T.Kojima,, T.Miura,, N.Iwasawa
  • Journal Title: Angew.Chem.Int.Ed. 45 Pages: 6874-6877
• [Journal Article] W(CO)_5(L)-Catalyzed Tandem Intramolecular Cyclopropanation / CopeRearrangement for the Stereoslective Constrction of Bicyclo〔5.3.0〕decane Framework (2006)
  • Author(s): H.KUsama, Y.Onizawa, N.Iwasawa
  • Journal Title: J.Am.Chem.Soc. 128 Pages: 16500-16501
• [Journal Article] Synthetic Studies and Mechanistic Insight on W(CO)5(L)-Catalyzed Stereoselective Construction of Functionalized Bicyclo[5. 3. 0]decane Framework
  • Author(s): Y. Onizawa, M. Hara, T. Hashimoto, H. Kusama, N. Iwasawa
  • Journal Title: Chem. Eur. J., accepted
  • Peer Reviewed
• [Presentation] [3+2]-Cycloaddition Reaction of Platinum-Containing Carbonyl Ylides for the Preparation of Fused Carbocycles (2009)
  • Author(s): 渡辺英一, 石田健人, 草間博之, 岩澤伸治
  • Organizer: The 11th International Kyoto Conference on New Aspects of Organic Chemistry
  • Place of Presentation: Kyoto
  • Year and Date: 2009-11-11
• [Presentation] レニウム触媒を用いるシリルエノールエーテル部位を有するプロパルギルエステル誘導体からの多置換フェノール合成 (2009)
  • Author(s): 齊藤巧泰、鬼澤裕二、草間博之、岩澤伸治
  • Organizer: 第96回有機合成シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2009-11-06
• [Presentation] 白金触媒を用いたアレニルシリルエーテルとビニルエーテルとの分子間3+2付加環化反応 (2009)
  • Author(s): 海老澤雅、舟見英哲、草間博之、岩澤伸治
  • Organizer: 第56回有機金属化学討論会
  • Place of Presentation: 京都
  • Year and Date: 2009-09-10
• [Presentation] レニウム(I)触媒によるジエンーイン類の環化反応:含窒素環状化合物の選択的合成 (2009)
  • Author(s): 苅部雄輔、今井理恵、鬼澤裕二、草間博之、岩澤伸治
  • Organizer: 第56回有機金属化学討論会
  • Place of Presentation: 京都
  • Year and Date: 2009-09-10
• [Presentation] [3+2]-Cycloaddition of Platinum-Containing Carbonyl Ylides Derived from Linear γ, δ-Ynones (2009)
  • Author(s): 石田健人, 草間博之, 岩澤伸治
  • Organizer: 15th IUPAC Symposium on Organometallic Chemistry Directed Towards Organic Synthesis
  • Place of Presentation: Glasgows
  • Year and Date: 2009-07-27
• [Presentation] 白金含有カルボニルイリドを活性種とする多環性骨格構築法 (2009)
  • Author(s): 渡辺英一、石田健人、草間博之、岩澤伸治
  • Organizer: 第95回有機合成シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2009-06-10
• [Presentation] ロジウム触媒を用いる末端アルキンとα, β-不飽和イミン類との分子間[4+1]型付加環化反応 (2009)
  • Author(s): 水野明夫、草間博之、岩澤伸治
  • Organizer: 第57回有機合成化学協会関東支部シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2009-05-09
• [Presentation] 白金含有カルボニルイリドとビニルエーテルとの[3+2]型付加環化反応-カチオン性白金ホスフィン錯体による反応経路の制御- (2009)
  • Author(s): 石田健人、草間博之、岩澤伸治
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 日本大学理工学部船橋キャンパス(千葉)
  • Year and Date: 2009-03-29
• [Presentation] 白金含有アゾメチンイリドの[3+2]付加環化反応を利用した Yuremamine の合成研究 (2009)
  • Author(s): 内田雅子、宮下佑一、草間博之、岩澤伸治
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 日本大学理工学部船橋キャンパス(千葉)
  • Year and Date: 2009-03-29
• [Presentation] タングステン(0)触媒を用いるトリエンイン類の連続環化反応に基づくビシクロ[5.3.0]デカン誘導体の立体選択的合成 (2009)
  • Author(s): 鬼澤裕二、草間博之、岩澤伸治
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 日本大学理工学部船橋キャンパス(千葉)
  • Year and Date: 2009-03-27
• [Presentation] レニウム触媒を用いるシリルエノールエーテル部位を有するプロパルギルエステル誘導体からの多置換フェノールの合成 (2009)
  • Author(s): 齊藤巧泰、鬼澤裕二、草間博之、岩澤伸治
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 日本大学理工学部船橋キャンパス(千葉)
  • Year and Date: 2009-03-27
• [Presentation] A New Alkyne Activation Strategy for the Construction of Polycyclic Carbon Skeletons (2008)
  • Author(s): 岩澤伸治
  • Organizer: 1^<st> PKU-Eli Lilly Symposium of Organic Chemistry
  • Place of Presentation: Beijing、China
  • Year and Date: 2008-12-20
• [Presentation] 白金触媒を用いたアレニルシリルエーテルとビニルエーテル類の分子間付加環化反応 (2008)
  • Author(s): 海老澤雅、舟見英哲、草間博之、岩澤伸治
  • Organizer: 第56回有機合成化学協会関東支部シンポジウム
  • Place of Presentation: 新潟大学工学部
  • Year and Date: 2008-11-30
• [Presentation] 白金含有カルボニルイリドを活性種とする分子内[3+2]付加環化反応 (2008)
  • Author(s): 渡辺英一、石田健人、草間博之、岩澤伸治
  • Organizer: 第25回有機合成化学セミナー
  • Place of Presentation: 阿蘇プラザホテル
  • Year and Date: 2008-09-08
• [Presentation] 鎖状γ, δ-イノ・ンからの白金含有カルボニルイリドの生成とその反応 (2008)
  • Author(s): 石田健人、渡辺英一、草間博之、岩澤伸治
  • Organizer: 第93回有機合成シンポジウム
  • Place of Presentation: 東京工業大学大岡山キャンパス(東京)
  • Year and Date: 2008-09-08
• [Presentation] Efficient Control of π-Alkyne and Vinylidene Complex Pathways for the W(CO)_5(L)-Catalyzed Synthesis of Two Types of Nitrogen-Containing Bicyclic Compounds (2008)
  • Author(s): 鬼澤裕二, 草間博之, 岩澤伸治
  • Organizer: Third International Conference on Advanced Organic Synthesis Directed toward the Ultimate Efficiency and Practicability
  • Place of Presentation: 大津プリンスホテル(滋賀)
  • Year and Date: 2008-05-26
• [Presentation] A New Alkyne Activation Strategy for the Construction of Polycyclic Carbon Skeletons (2008)
  • Author(s): 岩澤伸治
  • Organizer: The Second International Symposium on Concerto Catalysis
  • Place of Presentation: Tokyo
  • Year and Date: 2008-04-18
• [Presentation] タングステン触媒を用いた連続環化反応に基づく多官能性ビシクロ[5.3.0]デカン誘導体の合成 (2008)
  • Author(s): 原 雅寛、鬼澤裕二、草間博之、岩澤伸治
  • Organizer: 日本化学会第88春季年会
  • Place of Presentation: 立教大学池袋キャンパス(東京)
  • Year and Date: 2008-03-29
• [Presentation] ナフタライン-ヘキサカルボニルジコバルト錯体の合成と反応 (2008)
  • Author(s): 大塚麻依子、山下聡美、鷹谷 絢、岩澤伸治
  • Organizer: 日本化学会第88春季年会
  • Place of Presentation: 立教大学池袋キャンパス(東京)
  • Year and Date: 2008-03-29
• [Presentation] ロジウム触媒を用いる末端アルキンとα,β-不飽和イミン類との分子間[4+1]型付加環化反応 (2008)
  • Author(s): 水野明夫、草間博之、岩澤伸治
  • Organizer: 日本化学会第88春季年会
  • Place of Presentation: 立教大学池袋キャンパス(東京)
  • Year and Date: 2008-03-28
• [Presentation] レニウム(I)触媒を用いるジエン-イン類の環化反応に基づく含窒素環状化合物の合成 (2008)
  • Author(s): 今井理恵、苅部雄輔、鬼澤裕二、草間博之、岩澤伸治
  • Organizer: 日本化学会第88春季年会
  • Place of Presentation: 立教大学池袋キャンパス(東京)
  • Year and Date: 2008-03-28
• [Presentation] 白金触媒を用いたアレニルシリルエーテルとビニルエーテル類の分子間付加環化反応 (2008)
  • Author(s): 海老澤雅、舟見英哲、草間博之、岩澤伸治
  • Organizer: 日本化学会第88春季年会
  • Place of Presentation: 立教大学池袋キャンパス(東京)
  • Year and Date: 2008-03-26
• [Presentation] A New Alkyne Activation Strategy for the Construction of Polycyclic Carbon Skeletons (2008)
  • Author(s): N. Iwasawa
  • Organizer: 1st PKU-Eli Lilly Symposium of Organic Chemistry
  • Place of Presentation: Beijing、China
• [Presentation] Construction of Polycyclic Carbon Skeleton Based on Geminal Carbo-functionalization of Alkynes (2008)
  • Author(s): N. Iwasawa
  • Organizer: 5th Asian-European Symposium on Metal Mediated Efficient Organic Synthesis
  • Place of Presentation: Obernai, France
• [Presentation] Novel Method for Construction of Polycyclic of Polycyclic Compounds Utilizing Transition Metal-Containing Ylides (2007)
  • Author(s): Hiroyuki Kusama, Yuichi Miyashita, Yasuo Suzuki, Jun Takaya, Nobuharu Iwasawa
  • Organizer: The 2nd International Conference on Cutting-edge Organic Chemistry
  • Place of Presentation: 釜山(韓国)
  • Year and Date: 2007-09-04
• [Presentation] Molybdenum(0)-Promoted Carbonylative Cyclization of ο-Halobenzaldimine and its Related Derivatives (2007)
  • Author(s): Jun Takaya, Kenichiro Sangu, Nobuharu Iwasawa
  • Organizer: Internaational Conference on Asymmetric Organocatalysis″ First International Conference on Advanced Organic Synthesis Directed toward the Ultimate Efficiency and Practicability
  • Place of Presentation: 滋賀県大津プリンスホテル
  • Year and Date: 2007-05-29
• [Presentation] Construction of Polycyclic Carbon Skeleton Based on Geminal Carbo-functionalization of Alkynes (2007)
  • Author(s): N. Iwasawa
  • Organizer: International Symposium on Catalysis and Fine Chemicals
  • Place of Presentation: Nanyang Technological University、Singapore
• [Presentation] Construction of Polycyclic Carbon Skeleton Based on Geminal Carbo-functionalization of Alkynes (2007)
  • Author(s): N. Iwasawa
  • Organizer: The 13th Korea-Japan Seminar on Organic Chemistry
  • Place of Presentation: Daejeon、韓国
• [Presentation] アルキン類の求電子的活性化に基づく触媒的炭素骨格構築ー0価6族金属カルボニル錯体の活用ー (2007)
  • Author(s): 岩澤伸治
  • Organizer: 日本化学会第87春季年会
• [Presentation] Gold-Catalyzed Tandem Cyclization of Dienynes for the Preparation of Bicyclo[4.3.0]nonane Derivatives (2007)
  • Author(s): Yusuke Karibe, Yuji Onizawa, Hiroyuki Kusama, Nobuharu Iwasawa
  • Organizer: The 14th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis
  • Place of Presentation: なら100年会館(奈良)
• [Presentation] [3+2]-Cycloaddition of Platinum-Containing Carbonyl Ylides Derived from Linear γδ-Ynones (2007)
  • Author(s): Kento Ishida, Hideaki Funami, Hiroyuki Kusama, Nobuharu Iwasawa
  • Organizer: The 14th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis
  • Place of Presentation: なら100年会館(奈良)
• [Presentation] Synthesis of Naphthalyne-cobalt Complexes (2007)
  • Author(s): Maiko Otsuka, Satomi Yamashita, Masao Aoki, Jun Takaya, Nobuharu Iwasawa
  • Organizer: The 14th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis
  • Place of Presentation: なら100年会館(奈良)
• [Presentation] W(CO)5(L)-Catalyzed Formation of Aza-azomethine Ylides and Subsequent[3+2]-Cycloaddition Reactions with Olefins (2007)
  • Author(s): Antoine Grandmarre, Hiroyuki Kusama, Nobuharu Iwasawa
  • Organizer: The 14th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis
  • Place of Presentation: なら100年会館(奈良)
• [Presentation] 金属含有アゾメチンイリドを活性種とする多官能性三環性インドールの合成 (2007)
  • Author(s): 内田雅子・原雅寛・宮下佑一・草間博之・岩澤伸治
  • Organizer: 第24回有機合成化学セミナー
  • Place of Presentation: 淡路夢舞台国際会議場(淡路)
• [Presentation] 環状アルキン-コバルトカルボニル錯体の[4+2]付加環化反応 (2007)
  • Author(s): 大井 勲・稲葉 健一・鷹谷 絢・岩澤 伸治
  • Organizer: 第24回有機合成化学セミナー
  • Place of Presentation: 淡路夢舞台国際会議場(淡路)
• [Presentation] W(CO)_5(L)-Catalyzed Synthesis of Two Types of Nitrogen-Containing Bicyclic Compounds by Controlling p-Alkyne and Vinylidene Complex Pathways (2007)
  • Author(s): Yuji Onizawa, Hiroyuki Kusama, Nobuharu Iwasawa
  • Organizer: 第54回有機金属化学討論会
  • Place of Presentation: 広島大学東広島キャンパス
• [Presentation] Generation and Reaction of Tungsten(0)-Containing Ammonium Ylide (2007)
  • Author(s): Shuji Udagawa, Jun Takaya, Hiroyuki Kusama, and Nobuharu Iwasawa
  • Organizer: 第54回有機金属化学討論会
  • Place of Presentation: 広島大学東広島キャンパス(広島)
• [Presentation] Construction of Polycyclic Carbon Skeleton Based on Geminal Carbo-functionalization of Alkynes (2007)
  • Author(s): Nobuharu Iwasawa
  • Organizer: The 13th Korea-Japan Seminar on Organic Chemistry
  • Place of Presentation: KAIST(Daejeon,韓国)
• [Presentation] Construction of Polycyclic Carbon Skeleton Based on Geminal Carbofunctionalization of Alkynes (2007)
  • Author(s): Nobuharu Iwasawa
  • Organizer: International Symposium on Catalysis and Fine Chemicals
  • Place of Presentation: Nanyang Technological University(Singapore)
• [Book] “Group 6 Metal Vinylidenes in Catalysis"in“Metal Vinylidenes and Allenylidenes in Catalysis" (2008)
  • Author(s): N. Iwasawa
  • Publisher: Wiley-VCH