Identification of host factors involved in RNA replication of dianthovirus and its RNA silencing suppression
| Project/Area Number |
18208004
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Plant pathology
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| Research Institution | Kyoto University |
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Principal Investigator |
OKUNO Tetsuro Kyoto University, 大学院・農学研究科, 教授 (00221151)
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| Project Period (FY) |
2006 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
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| Budget Amount *help |
¥46,930,000 (Direct Cost: ¥36,100,000、Indirect Cost: ¥10,830,000)
Fiscal Year 2008: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Fiscal Year 2007: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Fiscal Year 2006: ¥22,490,000 (Direct Cost: ¥17,300,000、Indirect Cost: ¥5,190,000)
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| Keywords | ウイルス / RNA / 複製 / 翻訳 / 病原性 / 抵抗性 / RNAサイレンシング / 植物 / キャップ非依存性翻訳 / リボレギュレーター / RNA複製酵素 / サプレッサー / RNA複製 |
|---|
| Research Abstract |
農業上の重要病原体の1つである植物ウイルスの複製機構を明らかにするため、ウイルスゲノムRNA複製装置に含まれるタンパク質とRNAを解析した。その結果、RNA複製に重要なタンパク質-タンパク質、およびタンパク質-RNA相互作用の分子基盤を明らかにした。また、ウイルスがRNA複製あるいはタンパク質の翻訳に利用すると考えられる植物タンパク質を同定した。
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Report
(4 results)
Research Products
(69 results)
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[Journal Article] A Viral Non-coding RNA Generated by cis-Element-mediated Protection against 5'→3' RNA Decay Represses Both Cap-independent and Cap-dependent Translation2008
Author(s)
Iwakawa, H., Mizumoto, H., Nagano, H., Imoto, Y., Takigawa, K., Sarawaneeyaruk, S., H., Kaido, M., Mise, K. and Okuno, T
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Journal Title
J. Virol 82(20)
Pages: 10162-10174
Related Report
Peer Reviewed
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[Journal Article] cis-Preferential requirement of a-1 frameshift product p88 for the replication of Red clover necrotic mosaic virus RNA12008
Author(s)
Okamoto, K., Nagano, H., Iwakawa, H., Mizumoto, H., Takeda, A., Kaido, M., Mise, K., and Okuno, T
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Journal Title
Virology 375
Pages: 205-212
Related Report
Peer Reviewed
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[Journal Article] Downregulation of the NbNACa1 gene encoding a movement-protein-interacting protein reduces cell-to-cell movement of Brome mosaic virus in Nicotiana benthamiana2007
Author(s)
Kaido, M., Y. Inoue, Y. Takeda, K. Takeda, M. Mori, A. Tamai, T. Meshi, T. Okuno, K. Mise
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Journal Title
Mol. Plant-Microbe Interact 20, (6)
Pages: 671-681
Related Report
Peer Reviewed
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[Presentation] A viral non-coding RNA generated by cis-element-mediated protection against 5'→3' decay represses both cap-independent and dependent translation2008
Author(s)
Iwakawa, H., Mizumoto, H., Imoto, Y., Takigawa, K., Sarawaneeyaruk, S., Kaido, M., Mise, K., Okuno, T
Organizer
XIV. International Congress of Virology
Place of Presentation
Istanbul, Turkey
Year and Date
2008-08-13
Related Report
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[Presentation] Host-specific roles of the 5' untranslated region(UTR)of Red clover necrotic mosaic virus RNA1 in cap-independent translation XIV2008
Author(s)
Sarawaneeyaruk, S., Murakami, H., Iwakawa, H., Kaido, M., Mise, K., and Okuno T
Organizer
International Congress of Virology
Place of Presentation
stanbul, Turkey
Year and Date
2008-08-13
Related Report
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