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Brain energy-sensing mechanism controlling reproduction and food intake.

Research Project

Project/Area Number 18208025
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Basic veterinary science/Basic zootechnical science
Research InstitutionNagoya University

Principal Investigator

MAEDA Kei-ichiro  Nagoya University, 大学院・生命農学研究科, 教授 (30181580)

Co-Investigator(Kenkyū-buntansha) 上野山 賀久  名古屋大学, 大学院・生命農学研究科, 助教 (70324382)
Co-Investigator(Renkei-kenkyūsha) UENOYAMA Yoshihisa  名古屋大学, 大学院・生命農学研究科, 助教 (70324382)
Project Period (FY) 2006 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥45,500,000 (Direct Cost: ¥35,000,000、Indirect Cost: ¥10,500,000)
Fiscal Year 2009: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Fiscal Year 2008: ¥11,570,000 (Direct Cost: ¥8,900,000、Indirect Cost: ¥2,670,000)
Fiscal Year 2007: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Fiscal Year 2006: ¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000)
Keywords上位細胞 / ケトン体 / エネルギーセンサー / 摂食 / 血糖センサー / 神経ペプチド / ノルアドレナリン作動性神経 / 糖尿病 / LH分泌 / 乳酸 / 血糖値 / 脂肪酸 / エネルギー感知 / エネルギー / 脳 / 上衣細胞 / カルシウム / センサー
Research Abstract

The present research project aims to demonstrate the presence of 'energy sensor' in the brain, Hindbrain ependymocytes are the candidate for the sensor detecting the blood levels of glucose, fatty acids and ketone bodies and integrating the information to regulate feeding, reproduction and energy homeostatis via specific neural pathways.

Report

(6 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report   Self-evaluation Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (157 results)

All 2010 2009 2008 2007 2006 Other

All Journal Article (57 results) (of which Peer Reviewed: 33 results) Presentation (93 results) Book (5 results) Remarks (2 results)

  • [Journal Article] Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat.2010

    • Author(s)
      Wakabayashi, Y., Nakada, T., Murata, K., Ohkura, S., Mogi, K., Navarro, M., V., Clifton, K., D., Mori, Y., Tsukamura, H., Maeda, K.-I., Steiner, A., R., Okamura, H.
    • Journal Title

      Journal of Neuroscience 30(8)

      Pages: 3124-3132

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Kisspeptin/metastinと生殖機能制御 (株式会社中外医学社)2010

    • Author(s)
      冨川順子・上野山賀久・束村博子・前多敬一郎
    • Journal Title

      Annual Review糖尿病・代謝・内分泌2010

      Pages: 206-212

    • Related Report
      2009 Final Research Report
  • [Journal Article] Sexual Differentiation of Kisspeptin Neurons Responsible for Sex Difference in Gonadotropin Release in Rats2010

    • Author(s)
      Tsukamura, H., Homma, T., Tomikawa, J., Uenoyama Y., Maeda. K.-I.
    • Journal Title

      Annals of the New York Academy of Sciences (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular characterization and estrogen regulation of hypothalamic Kiss1 gene in the pig2010

    • Author(s)
      Tomikawa, J., Homma, T., Tajima, S., Shibata, T., Inamoto, Y., Takase, K., Inoue, N., Ohkura, S., Uenoyama, Y., Maeda. K.-I., Tsukamura, H.
    • Journal Title

      Biology of Reproduction (in press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat2010

    • Author(s)
      Wkabayashi, Y., Nakada, T., Murata, K., Ohkura, S., Mogi, K., Navarro, M., V., Clifton, K., D., Mori, Y., Tsukamura, H., Maeda. K.-I., Steiner, A., R., Okamura, H.
    • Journal Title

      Journal of Neuroscience 30(8)

      Pages: 3124-3132

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gonadotrophin-releasing hormone pulse generator activity in the hypothalamus of the goat.2009

    • Author(s)
      Ohkura, S., Takase, K., Matsuyama, S., Mogi, K., Ichimura, T,, Wakabayashi, Y., Uenoyama, Y., Mori, Y., Steiner, R.A., Tsukamura, H., Maeda, K.-I., Okamura, H.
    • Journal Title

      Journal of Neuroendocrinology 21

      Pages: 813-821

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Kisspeptin/metastin: A Key Molecule Controlling Two Modes of Gonadotrophin-releasing Hormone/Luteinising Hormone Release in Female Rats.2009

    • Author(s)
      Uenoyama Y, Tsukamura H, Maeda K.-I.
    • Journal Title

      Journal of Neuroendocrinology 21(4)

      Pages: 299-304

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Physiological role of metastin/kisspeptin in regulating gonadotropin-releasing hormone (GnRH) secretion in female rats2009

    • Author(s)
      Ohkura, S., Uenoyama, Y., Yamada, S., Homma, T., Takase, K., Inoue, N., Maeda, K.-I., Tsukamura, H.
    • Journal Title

      Peptides 30(1)

      Pages: 49-56

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Possible Role of Oestrogen in Pubertal Increase of Kissl/Kisspeptin Expression in Discrete Hypothalamic Areas of Female Rats.2009

    • Author(s)
      Takase, K., Uenoyama, Y., Inoue, N., Matsui, H., Yamada, S., Shimizu, M., Homma, T., Tomikawa, J., Kanda, S., Matsumoto, H., Oka, Y., Tsukamura, H., Maeda, K.-I.
    • Journal Title

      Journal of Neuroendocrinology. 21(6)

      Pages: 527-37

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Food deprivation induces monocarboxylate transporter 2 expression in the brainstem of female rat.2009

    • Author(s)
      Matsuyama, S., Ohkura, S., Iwata, K., Uenoyama, Y., Tsukamura, H., Maeda, K.-I., Kimura, K.
    • Journal Title

      Journal of Reproduction and Development 55

      Pages: 256-261

    • NAID

      10024942246

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Significance of neonatal testicular sex steroids to defeminize anteroventral periventricular kisspeptin neurons and the GnRH/LH surge system in male rats2009

    • Author(s)
      Homma, T., Sakakibara, M., Yamada, S., Kinoshita, M., Iwata, K., Tomikawa, J., Kanazawa, T., Matsui, H., Takatsu, Y., Ohtaki, T., Matsumoto, H., Uenoyama, Y., Maeda. K.-I., Tsukamura, H.
    • Journal Title

      Biology of Reproduction 81(6)

      Pages: 1216-1225

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gonadotrophin-releasing hormone pulse generator activity in the hypothalamus of the goat2009

    • Author(s)
      Ohkura, S., Takase, K., Matsuyama, S., Mogi, K., Ichimura, T., Wakabayashi, Y., Uenoyama, Y., Mori, Y., Steiner, R.A., Tsukamura, H., Maeda. K.-I., Okamura, H.
    • Journal Title

      Journal of Reproduction and Development 21

      Pages: 813-821

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Possible Role of Oestrogen in Pubertal Increase of Kiss1/Kisspeptin Expression in Discrete Hypothalamic Areas of Female Rats2009

    • Author(s)
      Takase, K., Uenoyama, Y., Inoue, N., Matsui, H., Yamada, S., Shimizu, M., Homma, T., Tomikawa, J., Kanda, S., Matsumoto, H., Oka, Y., Tsukamura. H., Maeda, K.-I.
    • Journal Title

      Journal of Neuroendocrinology 21(6)

      Pages: 527-537

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Potencies of centrally- or peripherally-injected full-length kisspeptin or its C-terminal decapeptide on LH release in intact male rats2009

    • Author(s)
      Pheng, V., Uenoyama, Y., Homma T., Inamoto Y., Takase K., Yoshizawa K., Isaka S., Watanabe T., Ohkura S., Tomikawa J., Maeda K.-I., Tsukamura, H.
    • Journal Title

      Journal of Reproduction and Development 55

      Pages: 378-382

    • NAID

      10025194159

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Possible Role of Oestrogen in Pubertal Increase of Kissl/Kisspep tin Expression in Discrete Hypothalamic Areas of Female Rats.2009

    • Author(s)
      Takase K., Uenoyama Y., Inoue N., Matsui H., Yamada S., Shimizu M., Homma T., Tomikawa J., Kanda S., Matsumoto H., Oka Y., TsukamuraH., Maeda K. -I.
    • Journal Title

      Journal of Neuroendocrinology (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Potencies of Centrally- or Peripherally-Injected Full-Length Kissp eptin or Its C-Terminal Decapeptide on LH Release in Intact Male Rats.2009

    • Author(s)
      Pheng, V., Uenoyama, Y., Homma T., Inamoto Y., TakaseK., Yoshizawa K., Isaka S., Watanabe T., Ohkura S., Tomikawa J., Maeda K. -I., Tsukamura, H.
    • Journal Title

      Journal of Reproduction and Development (in press)

    • NAID

      10025194159

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Food Deprivation Induces Monocarboxylate Transporter 2 Expres sion in the Brainstem of Female Rat.2009

    • Author(s)
      Matsuyama S, Ohkura S, Iwata K, Uenoyama Y, Tsukamura H, Maeda K. -L, KimuraK.
    • Journal Title

      Journal of Reproduction and Development. (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oestrogen-dependent stimulation of luteinising hormone release by galanin-like peptide in female rats.2008

    • Author(s)
      Uenoyama, Y., Tsukamura, H., Kinoshita, M., Yamada, S., Iwata, K., Pheng, V., Sajapitak, S., Sakakibara, M., Ohtaki, T., Matsumoto, H., Maeda, K,-I
    • Journal Title

      Journal of Neuroendocrinology 20

      Pages: 626-631

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Central lipoprivation-induced suppression of LH pulses is mediated by paraventricular catecholaminergic inputs in female rats.2008

    • Author(s)
      Sajapitak, S., Iwata, K., Shahab, M., Uenoyama, Y., Yamada, S., Kinoshita, M., Bari, F.Y., I'Anson, H., Tsukamura, H., Maeda, K.-I.
    • Journal Title

      Endocrinology 149

      Pages: 3016-3024

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Paraventricularα1-andα2-adrenergic receptors mediate hindbrain lipoprivation-induced suppression of luteinizing hormone pulses in female rats.2008

    • Author(s)
      Sajapitak, S., Uenoyama, Y., Yamada, S., Kinoshita, M., Iwata, K., Bari, F.Y., I' Anson, H., Tsukamura, H., Maeda, K.-I.
    • Journal Title

      Journal of Reproduction and Development 54

      Pages: 198-202

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Oestrogen-dependent stimulation of luteinising hormone release by galanin-like peptide in female rats2008

    • Author(s)
      Uenoyama, Y., Tsukamura, H., Kinoshita, M., Yamada, S., Iwata, K., Pheng, V., Sajapitak, S., Sakakibara, M., Ohtaki, T., Matsumoto, H., Maeda and K.-I.
    • Journal Title

      Journal of Neuroendocrinology 20

      Pages: 626-631

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Central lipoprivation-induced suppression of LH pulses is mediated by paraventricular catecholaminergic inputs in female rats2008

    • Author(s)
      Sajapitak, S., Iwata, K., Shahab, M., Uenoyama, Y., Yamada, S., Kinoshita, M., Bari, F.Y., I'Anson, H., Tsukamura, H. and Maeda, K.-I
    • Journal Title

      Endocrinology 149

      Pages: 3016-3024

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Paraventricular α1- and α2-adrenergic receptors mediate hindbrain lipoprivation-induced suppression of luteinizing hormone pulses in female rats2008

    • Author(s)
      Sajapitak, S., Uenoyama, Y., Yamada, S., Kinoshita, M., Iwata, K., Bari, F.Y., I'Anson, H., Tsukamura, H and Maeda, K.-I.
    • Journal Title

      Journal of Reproduction and Development 54

      Pages: 198-202

    • NAID

      10021219381

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Identification of KiSS-1 product kisspeptin and steroid-sensitive sexually dimorphic kisspeptin neurons in medaka (oryzias latipes ).2008

    • Author(s)
      Kanda, S., Akazome, Y., Matsunaga, T., Yamamoto, N., Yamada, S., Tsukamura, H., Maeda, K. -I., Oka, Y.
    • Journal Title

      Endoerinology 149

      Pages: 2467-2477

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Paraventricular α 1- and α 2-adrenergic receptors mediate hindbr ain lipoprivation-induced suppression of luteinizing hormone pulses in female rats.2008

    • Author(s)
      Sajapitak, S., Uenoyama, Y., Yama da, S., Kinoshita, M., Iwata, K, Bari, F. Y., I'Anson, H., Tsukamura, H., Ma eda, K. -I.
    • Journal Title

      Journal of Reproduction and Development 54

      Pages: 198-202

    • NAID

      10021219381

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oestrogen-dependent stimulation of luteinising hormone release by galanin-like peptide in female rats.2008

    • Author(s)
      Uenoyama, Y., Tsukamura, H., Kinoshita, M., Yamada, S., Iwata, K., Pheng, V, Sajapitak, S., Sakakibara, M., Ohtaki, T., Matsumoto, H., Maeda, K. -I.
    • Journal Title

      Journal of Neuroendocrinology 20

      Pages: 626-631

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Central lipoprivation-induced suppression of LH pulses is mediated by paraventricular catecholaminergic inputs in female rats.2008

    • Author(s)
      Sajapitak, S.
    • Journal Title

      Endocrinology

      Pages: 3016-3024

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oestrogen-Dependent Stimulation of Luteinising Hormone. Release by Galanin-Like Peptide (GALP) in Female Rats.2008

    • Author(s)
      Uenoyama, Y.
    • Journal Title

      Journal of Neuroendocrinology (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Paraventricular a1-and a 2-adrenergic receptors mediate hindbrain lipoprivation-induced suppression of luteinizing Norm one pulses in female rats.2008

    • Author(s)
      Sajapitak, S.
    • Journal Title

      Journal of Reproduction and Development (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 繁殖機能を制御するエネルギーセンサーとその応用の可能性 -特集 家畜における栄養と繁殖機能についての最前線-2007

    • Author(s)
      岩田衣世、束村博子、前多敬一郎
    • Journal Title

      獣医畜産新報 60

      Pages: 455-460

    • NAID

      40015515543

    • Related Report
      2009 Final Research Report
  • [Journal Article] 繁殖機能を制御するエネルギーセンサーとその応用の可能性2007

    • Author(s)
      岩田衣世、束村博子、前多敬一郎
    • Journal Title

      特集家畜における栄養と繁殖機能についての最前線-獣医畜産新報 60

      Pages: 455-460

    • Related Report
      2008 Self-evaluation Report
  • [Journal Article] Metastin/kisspeptin and control of estrous cycle in rats.2007

    • Author(s)
      Maeda, K.
    • Journal Title

      Reviews in Endocrine and Metabolic Disorders 8

      Pages: 21-29

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 繁殖機能を制御するエネルギーセンサーとその応用の可能性2007

    • Author(s)
      岩田衣世
    • Journal Title

      Journal of Veterinary Medicine 60-6

      Pages: 455-460

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 繁殖メカニズムの中核ペプチド、メタスチン(キスペプチン)をめぐる新しい性腺刺激剤の可能性(その1)2007

    • Author(s)
      前多敬一郎
    • Journal Title

      家畜人工授精 241

      Pages: 22-36

    • NAID

      40015587682

    • Related Report
      2007 Annual Research Report
  • [Journal Article] メタスチン-特集 中枢内分泌の最新知見とその異常-2007

    • Author(s)
      上野山賀久
    • Journal Title

      産科と婦人科 74-8

      Pages: 898-903

    • NAID

      40015569533

    • Related Report
      2007 Annual Research Report
  • [Journal Article] metastin(キスペプチンkisspeptin)とGnRH分泌-2007

    • Author(s)
      前多敬一郎
    • Journal Title

      日本比較内分泌学会ニュースJSCE 126

      Pages: 13-14

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 繁殖メカニズムの中核ペプチド、メタスチン(キスペプチン)をめぐる新しい性腺刺激剤の可能性(その2)2007

    • Author(s)
      前多敬一郎
    • Journal Title

      家畜人工授精 242

      Pages: 7-24

    • NAID

      40015666398

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 生理的GnRH放出因子,メタスチン(キスペプチン)の基礎と応用2007

    • Author(s)
      前多敬一郎
    • Journal Title

      家畜診療 54-10

      Pages: 589-594

    • NAID

      40015652235

    • Related Report
      2007 Annual Research Report
  • [Journal Article] メタスチン(キスペプチン):新しい繁殖制御の可能性を秘めた神経ペプチド2007

    • Author(s)
      前多敬一郎
    • Journal Title

      臨床獣医 25

      Pages: 62-65

    • Related Report
      2007 Annual Research Report
  • [Journal Article] メタスチン/キスペプチンー種を超えて生殖を司る神経ペプチドGnRHの上位にあって性腺刺激ホルモン分泌をコントロールする2007

    • Author(s)
      東村博子
    • Journal Title

      化学と生物 46-4

      Pages: 234-236

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Involvement of Anteroventral Periventricular Metastin/Kisspeptin Neurons in Estrogen Positive Feedback Action on Luteinizing Hormone Release in Female Rats.2007

    • Author(s)
      Adachi, S.,
    • Journal Title

      Journal of Reproduction and Development 53

      Pages: 367-378

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition of Metastin (Kisspeptin-54)-GPR 54 Signaling in the Arcuate Nucleus-Median Eminence Region during Lactation in Rats.2007

    • Author(s)
      Yamada S.
    • Journal Title

      Endocrinology 148(5)

      Pages: 2226-2232

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition of Metastin (Kisspeptin-54)-GPR 54 Signaling in the Arcuate Nucleus-Median Eminence Region during Lactation in Rats.2007

    • Author(s)
      Yamada, S.
    • Journal Title

      Endocrinology (published)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Involvement of Anteroventral Periventricular Metastin/Kisspeptin Neurons in Estrogen Positive Feedback Action on Luteinizing Hormone Release in Female Rats.2007

    • Author(s)
      Adachi, S.
    • Journal Title

      Journal of Reproduction and Development 53

      Pages: 367-378

    • Related Report
      2006 Annual Research Report
  • [Journal Article] メタスチン(キスペプチン) : 生殖機能を制御する神経ペプチド-新しいGPCRリガンド研究の現状と展望-2007

    • Author(s)
      前多敬一郎
    • Journal Title

      ホルモンと臨床 55

      Pages: 57-64

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Temporal expression of estrogen receptorαin the hypothalamus and medulla oblongata during fasting: a role of noradrenergic neurons.2006

    • Author(s)
      Reyes, B.A. S, Tsukamura, H., I' Anson, H., Estacio, M.A.C., Hirunagi, K., Maeda, K.-I.
    • Journal Title

      Journal of Endocrinology 190

      Pages: 593-600

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Temporal expression of estrogen receptor α in the hypothalamus and medulla oblongata during fasting : a role of noradrenergic neurons2006

    • Author(s)
      Reyes, B.A.S, Tsukamura, H., I'Anson, H., Estacio, M.A.C., Hirunagi, K. and Maeda, K.-I.
    • Journal Title

      Journal of Endocrinology 190

      Pages: 593-600

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Acute Lipoprivation Suppresses Pulsatile Luteinizing Hormone Secretion without Affecting Food Intake in Female Rats.2006

    • Author(s)
      Mohammad S.
    • Journal Title

      Journal of Reproduction and Development 52

      Pages: 763-772

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Temporal expression of estrogen receptor α in the hypothalamus and medulla oblongata during fasting : a role of noradrenergic neurons.2006

    • Author(s)
      B.A.S.Reyes
    • Journal Title

      Journal of Endocrinology 190

      Pages: 539-600

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Effects of exposure of rat dams to 1-bromopropane during pregnancy and lactation on growth and sexual maturation of their offspring.2006

    • Author(s)
      Furuhashi, K.
    • Journal Title

      Toxicology 224

      Pages: 219-228

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Anti-diabetic potentials of Momordica charantia and Andrographis paniculata and their effects on estrous cyclicity of alloxan-induced diabetic rats.2006

    • Author(s)
      B.A.S.Reyes
    • Journal Title

      Journal of Ethnopharmacology 105

      Pages: 196-200

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Role of Noradrenergic Receptors in the Bed Nucleus of the Stria Terminalis in Regulating Pulsatile Leteinizing Hormone Secretion in Female Rats.2006

    • Author(s)
      Yamada, S.
    • Journal Title

      Journal of Reproduction and Development 52

      Pages: 115-121

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Long-Day Suppressed Expression of Type 2 Deiodinase Gene in the Mediobasal Hypothalamus of the Saanen Goat, a Short-Day Breeder : Implication for Seasonal Window of Thyroid Hormone Action on Reproductive Neuroendocrine Axis.2006

    • Author(s)
      Yasuo, S.
    • Journal Title

      Endocrinology 147・1

      Pages: 432-440

    • Related Report
      2006 Annual Research Report
  • [Journal Article] メタスチン : 生殖機能を制御する中心的ペプチド 特集「GPCR研究の最前線」2006

    • Author(s)
      束村博子
    • Journal Title

      内分泌/糖尿病科 22・4

      Pages: 416-420

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The Impact of Stress on Reproduction : Are Glucocorticoids Inhibitory or Protective to Gonadotropin Secretion?2006

    • Author(s)
      Maeda, K. -I.
    • Journal Title

      Endocrinology 147・3

      Pages: 1085-1086

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Neuroendocrine mechanism mediating energetic regulation of gonadotropin release in female rats.2006

    • Author(s)
      Tsukamura, H.
    • Journal Title

      Animal Science Journal 77

      Pages: 259-265

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Identification of KISS-1. Product Kisspeptin and Steroid-Sensitive Sexually-Dimorphic Kisspeptin neurons in Medaka(Oryzias latipes).

    • Author(s)
      Kanda, S.
    • Journal Title

      Endocrinology 149(in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] Kisspeptin: a missing link in the regulation of GnRH release?2010

    • Author(s)
      Maeda K.I.
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2010-03-29
    • Related Report
      2009 Final Research Report
  • [Presentation] Kisspeptin : a missing link in the regulation of GnRH release?2010

    • Author(s)
      前多敬一郎
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2010-03-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] Kisspeptin neurons responsible for animal reproduction : Surge vs. pulse modes of GnRH/LH secretion and its sex difference2010

    • Author(s)
      束村博子, 前多敬一郎
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2010-03-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] Gonadotropin-releasing hormone pulse generator activity from the arcuate nucleus kisspeptin neurons in the goat hypothalamus2010

    • Author(s)
      大蔵聡, 若林嘉浩, 上野山賀久, Steiner R.A., 束村博子, 前多敬一郎, 岡村裕昭
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      国立京都国際会館
    • Related Report
      2009 Annual Research Report
  • [Presentation] Induction of ovulation by kisspeptin and its agonists in the musk shrew (Suncus murinus), a reflex ovulator2010

    • Author(s)
      井上直子, 佐々木有希, Oishi S., Fujii N., 上野山賀久, 山本直之, 束村博子, 前多敬一郎
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      国立京都国際会館
    • Related Report
      2009 Annual Research Report
  • [Presentation] Effect of neonatal estrogen on brain kisspeptin expression in adult mice : possible role of estrogen receptor α2010

    • Author(s)
      吉田佳絵, 本間珠実, 稲本瑶子, 富川順子, 上野山賀久, 前多敬一郎 束村博子
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      国立京都国際会館
    • Related Report
      2009 Annual Research Report
  • [Presentation] Molecular characterization of Kiss1 gene in the pig2010

    • Author(s)
      冨川順子, 本間珠実, 田嶋茂行, 柴田貴子, 稲本瑶子, 大蔵聡, 上野山賀久, 束村博子, 前多敬一郎
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      国立京都国際会館
    • Related Report
      2009 Annual Research Report
  • [Presentation] Acute trapping of peripubertal kisspeptin or leptin with antibodies to determine factors triggering the onset of puberty in female rats2010

    • Author(s)
      上野山賀久, Takase K., Hirata J., Tanaka A., 束村博子, 前多敬一郎
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      国立京都国際会館
    • Related Report
      2009 Annual Research Report
  • [Presentation] Central metastin/kisspeptin in the regulation of luteinizing hormone secretion2009

    • Author(s)
      束村博子, 前多敬一郎
    • Organizer
      36th International Congress of Physiological Sciences
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-08-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] 性腺機能をコントロールする中枢におけるkey molecule, キスペプチン(メタスチン)2009

    • Author(s)
      前多敬一郎
    • Organizer
      日本産科婦人科学会第61回学術講演会
    • Place of Presentation
      国立京都国際会館 (基調講演)
    • Year and Date
      2009-04-04
    • Related Report
      2009 Final Research Report
  • [Presentation] 性腺機能をコントロールする中枢における key molecule, キスペプチン (メタスチン)2009

    • Author(s)
      前多敬一郎
    • Organizer
      日本産科婦人科学会第61回学術講演会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-04-04
    • Related Report
      2009 Annual Research Report
  • [Presentation] 生殖を制御する神経ペプチド, メタスチン/キスペプチン2009

    • Author(s)
      束村博子, 前多敬一郎
    • Organizer
      第147回日本獣医学会学術集会
    • Place of Presentation
      栃木県総合文化センター
    • Year and Date
      2009-04-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] Ketone body is an orexigenic signal associated with diabetic hyperphagia in rats.2009

    • Author(s)
      Iwata, K., Kinoshita, M., Yamada, S., Uenoyama, Y., Tsukamura, H., Maeda, K. -I.
    • Organizer
      The 39th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago, USA
    • Related Report
      2009 Final Research Report
  • [Presentation] Identification and characterization of Kissl gene in pigs.2009

    • Author(s)
      Tomikawa, J., Homma, T., Tajima, S., Shibata, T., Yamamoto, N., Uenoyama, Y., Ohkura, S., Tsukamura, H., Maeda, K. -I.
    • Organizer
      The 39th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago, USA.
    • Related Report
      2009 Final Research Report
  • [Presentation] NPYはNPY-Y1受容体を介して弓状核キスペプチンニューロン神経活動を抑制する2009

    • Author(s)
      若林嘉浩、中田友明、村田健、大蔵聡、森裕司、前多敬一郎、岡村裕昭
    • Organizer
      日本畜産学会第111回大会
    • Place of Presentation
      琉球大学(沖縄)
    • Related Report
      2009 Final Research Report
  • [Presentation] Neurokinin B as a Cotransmitter in Kisspeptin Neurons in the Regulation of Pulsatile GnRH Secretion2009

    • Author(s)
      若林嘉浩, 中田友明, 村田健, 大蔵聡, Navarro, V.M., 森裕司, 束村博子, 前多敬一郎, Steiner, R.A., 岡村裕昭
    • Organizer
      The 39th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] Functional Significance of Dynorphin as a Cotransmitter in Kisspeptin Neurons in the Regulation of Pulsatile GnRH Secretion2009

    • Author(s)
      大蔵聡, 若林嘉浩, 中田友明, 村田健, Navarro, V.M., 森裕司, 束村博子, 前多敬一郎, Steiner R.A., 岡村裕昭
    • Organizer
      The 39th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] Identification and characterization of Kiss1 gene in pigs2009

    • Author(s)
      冨川順子, 本間珠実, 田嶋茂行, 柴田貴子, 山本直之, 上野山賀久, 大蔵聡, 束村博子, 前多敬一郎
    • Organizer
      The 39th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] Ketone body is an orexigenic signal associated with diabetic hyperphagia in rats2009

    • Author(s)
      岩田衣世, Kinoshita, M., Yamada, S., 上野山賀久, 束村博子, 前多敬一郎
    • Organizer
      The 39th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] Absence of neonatal sex steroids rescues anteroventral periventricular kisspeptin neurons and GnRH/LH surge system in male rats2009

    • Author(s)
      本間珠実, Sakakibar, M., Yamada, S., Kinoshita, M., 岩田衣世, 冨川順子, 金沢哲広, 上野山賀久, 前多敬一郎, 束村博子
    • Organizer
      The 39th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] Potencies of full-length kisspeptin or its C-terminal decapeptide on luteinizing hormone release in intact male rats2009

    • Author(s)
      上野山賀久, Pheng, V., 本間珠実, 稲本瑶子, Yoshizawa-Kumagaye, K., Isaka, S., Watanabe, T.X., 前多敬一郎, 束村博子
    • Organizer
      The 39th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] ブタ卵巣におけるキスペプチン発現の解析2009

    • Author(s)
      井上直子, 平野隆之, 岡村裕昭, 上野山賀久, 束村博子, 前多敬一郎
    • Organizer
      日本畜産学会第111回大会
    • Place of Presentation
      琉球大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] スンクスの脳におけるGnRH神経細胞の分布とLHおよびFSH遺伝子のクローニング2009

    • Author(s)
      佐々木有希, 山本直之, 上野山賀久, 束村博子, 前多敬一郎, 井上直子
    • Organizer
      第102回日本繁殖生物学会大会
    • Place of Presentation
      近畿大学農学部キャンパス
    • Related Report
      2009 Annual Research Report
  • [Presentation] ブタ卵胞顆粒層細胞における Kiss1ならびにGpr54 mRNA発現の解析2009

    • Author(s)
      井上直子, 平野隆之, 岡村裕昭, 上野山賀久, 束村博子, 前多敬一郎
    • Organizer
      第102回日本繁殖生物学会大会
    • Place of Presentation
      近畿大学農学部キャンパス
    • Related Report
      2009 Annual Research Report
  • [Presentation] 性腺ステロイドホルモンによる視床下部弓状核キスペプチンニューロンの制御2009

    • Author(s)
      坂本光平, 若林嘉浩, 村田健, 大蔵聡, 前多敬一郎, 森裕司, 岡村裕昭
    • Organizer
      第102回日本繁殖生物学会大会
    • Place of Presentation
      近畿大学農学部キャンパス
    • Related Report
      2009 Annual Research Report
  • [Presentation] シバヤギ弓状核キスペプチンニューロン神経活動に対する Neurokinin Bの作用2009

    • Author(s)
      若林嘉浩, 中田友明, 村田健, 大蔵聡, Navarro VM, 森裕司, 束村博子, 前多敬一郎, Steiner RA, 岡村裕昭
    • Organizer
      第102回日本繁殖生物学会大会
    • Place of Presentation
      近畿大学農学部キャンパス
    • Related Report
      2009 Annual Research Report
  • [Presentation] シバヤギ弓状核キスペプチンニューロン神経活動の制御における Dynorphin Aの役割2009

    • Author(s)
      大蔵聡, 若林嘉浩, 中田友明, 村田健, Navarro VM, 森裕司, 束村博子, 前多敬一郎
    • Organizer
      第102回日本繁殖生物学会大会
    • Place of Presentation
      近畿大学農学部キャンパス
    • Related Report
      2009 Annual Research Report
  • [Presentation] ホルスタイン種経産牛へのキスペプチン末梢投与による黄体形成ホルモン分泌刺激効果2009

    • Author(s)
      勝野伸吾, 大蔵聡, 佐藤精, 大橋秀一, 小林一雄, 難波陽介, 上野山賀久, 束村博子, 前多敬一郎
    • Organizer
      第102回日本繁殖生物学会大会
    • Place of Presentation
      近畿大学農学部キャンパス
    • Related Report
      2009 Annual Research Report
  • [Presentation] 黄体期の黒毛和種雌ウシにおけるウシ型キスペプチン-10の性腺刺激ホルモン分泌刺激効果の検討2009

    • Author(s)
      難波陽介, 金沢哲広, 上野山賀久, 束村博子, 前多敬一郎, 大蔵聡
    • Organizer
      第102回日本繁殖生物学会大会
    • Place of Presentation
      近畿大学農学部キャンパス
    • Related Report
      2009 Annual Research Report
  • [Presentation] 視床下部弓状核キスペプチンニューロンの破壊がLHパルスに及ぼす影響2009

    • Author(s)
      岩田衣世, 大蔵聡, 上野山賀久, 束村博子, 前多敬一郎
    • Organizer
      第102回日本繁殖生物学会大会
    • Place of Presentation
      近畿大学農学部キャンパス
    • Related Report
      2009 Annual Research Report
  • [Presentation] ラットにおいて新生仔期の精巣由来の性ステロイドは前腹側室周囲核 (AVPV) のキスペプチン発現を特異的に脱雌化させる2009

    • Author(s)
      本間玲実, 岩田衣世, 冨川順子, 上野山賀久, 前多敬一郎, 束村博子
    • Organizer
      第102回日本繁殖生物学会大会
    • Place of Presentation
      近畿大学農学部キャンパス
    • Related Report
      2009 Annual Research Report
  • [Presentation] ブタ Kiss cDNAのクローニングと発現解析2009

    • Author(s)
      冨川順子, 本間珠実, 田嶋茂行, 柴田貴子, 稲本瑶子, 上野山賀久, 大蔵聡, 束村博子, 前多敬一郎
    • Organizer
      第102回日本繁殖生物学会大会
    • Place of Presentation
      近畿大学農学部キャンパス
    • Related Report
      2009 Annual Research Report
  • [Presentation] マウス前腹側室周囲核 (AVPV) キスペプチンニューロンにおける Bax を介したアポトーシス2009

    • Author(s)
      金沢哲広, 本間玲実, 冨川順子, 上野山賀久, 前多敬一郎, 束村博子
    • Organizer
      第102回日本繁殖生物学会大会
    • Place of Presentation
      近畿大学農学部キャンパス
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新生仔期エストロジェン投与が成熟マウス脳内キスペプチン発現に及ぼす影響 : エストロジェン受容体αの関与の可能性2009

    • Author(s)
      吉田佳絵, 本間玲実, 稲本瑶子, 冨川順子, 上野山賀久, 前多敬一郎, 束村博子
    • Organizer
      第102回日本繁殖生物学会大会
    • Place of Presentation
      近畿大学農学部キャンパス
    • Related Report
      2009 Annual Research Report
  • [Presentation] 脳領域得意的な Kiss1コンディショナルKOマウス作製二向けた Kiss-floxed マウスの作出2009

    • Author(s)
      平嶋昂, 富川順子, 今村拓也, 三寳誠, 冨田江一, 平林真澄, 上野山賀久, 束村博子, 前多敬一郎
    • Organizer
      第24回日本下垂体研究会
    • Place of Presentation
      古牧温泉青森屋
    • Related Report
      2009 Annual Research Report
  • [Presentation] マウス初期胚の発生における Kiss1発現とその機能2009

    • Author(s)
      深沼達也, 後藤哲平, 冨川順子, 上野山賀久, 束村博子, 前多敬一郎
    • Organizer
      第24回日本下垂体研究会
    • Place of Presentation
      古牧温泉青森屋
    • Related Report
      2009 Annual Research Report
  • [Presentation] ブタ Kiss1 cDNAのクローニングと視床下部での発現分布の解析2009

    • Author(s)
      冨川順子, 本間玲実, 田嶋茂行, 柴田貴子, 稲本瑶子, 上野山賀久, 大蔵聡, 束村博子, 前多敬一郎
    • Organizer
      第24回日本下垂体研究会
    • Place of Presentation
      古牧温泉青森屋
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヤギ視床下部におけるキスペプチン/Neurokinin B (NKB)/Dynorphin A (Dyn) 免疫陽性神経細胞の分布2009

    • Author(s)
      若林嘉浩, 坂本光平, 村田健, 大蔵聡, 森裕司, 前多敬一郎, 岡村裕昭
    • Organizer
      第24回日本下垂体研究会
    • Place of Presentation
      古牧温泉青森屋
    • Related Report
      2009 Annual Research Report
  • [Presentation] Localization of kisspeptin and gonadotropin-releasing hormone (GnRH) in developing ovarian follicles of pigs and goats2009

    • Author(s)
      井上直子, 平野隆之, 上野山賀久, 束村博子, 岡村裕昭, 前多敬一郎
    • Organizer
      Society for the Study of Reproduction 42st Annual Meeting
    • Place of Presentation
      David L.Lawrence Convention Center Pittsburgh
    • Related Report
      2009 Annual Research Report
  • [Presentation] 低栄養による繁殖機能低下の神経内分泌メカニズム:エネルギーシグナルとセンシングの観点から2008

    • Author(s)
      前多敬一郎
    • Organizer
      第101回日本繁殖生物学会シンポジウム「生殖のリスクファクター」
    • Place of Presentation
      九州大学
    • Year and Date
      2008-09-19
    • Related Report
      2009 Final Research Report
  • [Presentation] 低栄養による繁殖機能低下の神経内分泌メカニズム : エネルギーシグナルとセンシングの観点から2008

    • Author(s)
      前多敬一郎
    • Organizer
      第101回日本繁殖生物学会シンポジウム「生殖のリスクファクター」
    • Place of Presentation
      九州大学
    • Year and Date
      2008-09-19
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] 家畜の生体エネルギーバランスと繁殖機能:基礎からトランスレーショナルリサーチヘ2008

    • Author(s)
      前多敬一郎
    • Organizer
      (独)農業生物資源研究所問題別研究会
    • Place of Presentation
      (独)農業生物資源研究所、つくば
    • Related Report
      2009 Final Research Report
  • [Presentation] Role of kisspeptin (metastin)-GPR54 System in Regulating Surge- and Pulse-Modes of GnRH/onadotropin release in rats.2008

    • Author(s)
      Tsukamura, H., Homma, T., Yamada, S., Inamoto, Y., Inoue, N., Ohkura, S., Uenoyama, Y., Maeda, K.I.
    • Organizer
      1st world conference on kisspeptin signaling in the brain
    • Place of Presentation
      Cordoba, Spain.
    • Related Report
      2009 Final Research Report
  • [Presentation] 家畜の生体エネルギーバランスと繁殖機能:基礎からトランスレーショナルリサーチへ2008

    • Author(s)
      前多敬一郎
    • Organizer
      (独)農業生物資源研究所問題別研究会
    • Place of Presentation
      (独)農業生物資源研究所、つくば
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] Role of kisspeptin (metastin)-GPR54 System in Regulating Surge- and Pulse-Modes of GnRH/onadotropin release in rats2008

    • Author(s)
      Tsukamura, H., Homma, T., Yamada, S., Inamoto, Y., Inoue, N., Ohkura, S., Uenoyama, Y. and Maeda, K.I.
    • Organizer
      1st world conference on kisspeptin signaling in the brain
    • Place of Presentation
      Cordoba, Spain.
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] 家畜の生体エネルギーバランスと繁殖機能 : 基礎からトランスレーショナルリサーチヘ2008

    • Author(s)
      前多敬一郎
    • Organizer
      (独)農業生物資源研究所問題別研究会
    • Place of Presentation
      農業生物資源研究所、つくば
    • Related Report
      2008 Annual Research Report
  • [Presentation] DECREASED GONADAL ACTIVITIES BY ACTIVE IMMUNIZATION AGAINST KISSPEPTIN IN RATS.2008

    • Author(s)
      Uenoyama, Y., Inoue, N., Hasegawa, K., Tomikawa, J., Tsukamura, H., Maeda., K. I.
    • Organizer
      1^<st> world conference on kisspeptin signaling in the brain
    • Place of Presentation
      CORDOBA SPAIN
    • Related Report
      2008 Annual Research Report
  • [Presentation] MOLECUKLAR AND PHYSIOLOGIC CHARACTERIZATION OF THE PORCINE KISSl GENE AND PEPTIDE2008

    • Author(s)
      Tomikawa, J., Tajima, S., Shibata, T., Ohkura, S., Uenoyama, Y., Tsukamura, H., Maeda, K. I.
    • Organizer
      1^<st> world conference on kisspeptin signaling in the brain
    • Place of Presentation
      CORDOBA SPAIN
    • Related Report
      2008 Annual Research Report
  • [Presentation] GONADORTOPIN-RELEASING HORMONE PULSE GENERATOR ACTIVITY IN CLOSE PROXIMITY TO THE ARCUATE KISSPEPTIN NEURONS IN THE GOAT.2008

    • Author(s)
      Ohkura, S., Takase, K., Uenoyama, Y., Tsukamura, H., Maeda, K. I., Okamura, H.
    • Organizer
      1^<st> world conference on kisspeptin signaling in the brain
    • Place of Presentation
      CORDOBA SPAIN
    • Related Report
      2008 Annual Research Report
  • [Presentation] KISSPEPTIN FIBERS DIRECTLY CONTACT WITH GONADOT ROPIN-RELEASING HORMONE FIBERS IN THE MEDIAN EM INENCE OF FEMALE RATS.2008

    • Author(s)
      Inoue, N., Pheng, V., Inamoto, Y., Uenoyama, Y., Tsukamura, H., Ichikawa, M., Maeda, K. I.
    • Organizer
      1^<st> world conference on kisspeptin signaling in the brain
    • Place of Presentation
      CORDOBA SPAIN
    • Related Report
      2008 Annual Research Report
  • [Presentation] DISTRIBUTION OF KISSPEPTIN NEURONS IN THE SHIBA GOAT BRAIN : AN IMMUNOHISTOCHMICAL STUDY USING TWO POLYCLONAL ANTIBODIES AGAINST DEIFFERENT EPITOPES OF GOAT KISSPEPTIN.2008

    • Author(s)
      Nakada, T., Wakabayashi, Y., Ohkura, S., Maeda. K. I., Okamura, H.
    • Organizer
      1^<st> world conference on kisspept in signaling in the brain
    • Place of Presentation
      CORDOBA SPAIN
    • Related Report
      2008 Annual Research Report
  • [Presentation] KISSPEPTIN NEURONS IN GHE ARCUATE NUCLEUS OF GOATS RECEIVE NEURAL PROJECTIONS FROM THE MEDIAL NUCLEUS OF AMYGDALA, A KEY NUCLEUS FOR THE PHEROMONE SIGNALING PATHWAY.2008

    • Author(s)
      Wakabayashi, Y., Mogi, K., Nakada, T., Murata, K, Ohkura, S., Mori, Y., Maeda, K. I., Okamura, H.
    • Organizer
      1^<st> world conference on kisspeptin signaling in the brain
    • Place of Presentation
      CORDOBA SPAIN
    • Related Report
      2008 Annual Research Report
  • [Presentation] KISSPEPTIN AND ATEROID-SENSITIVE SEXUALLY DIMORPHIC KISSPEPTIN NEURONS IN MEDAKA(ORYZIAS LATIPES)2008

    • Author(s)
      Kanda, S., Akazome, Y., Matsunaga, T., Yamamoto, N., Yamada, S., Tsukamura, H., Maeda, K. I., Oka, Y.
    • Organizer
      1^<st> world conference on kisspeptin signaling in the brain
    • Place of Presentation
      CORDOBA SPAIN
    • Related Report
      2008 Annual Research Report
  • [Presentation] Role of KISSPEPTIN(METASTIN)-GPR54 System in Regulating Surge- and Pulse-Modes of GnRH/GONADOTORPIN RELEASE IN RATS.2008

    • Author(s)
      Tsukamura, H., Homma, T., Yamada, S., Inamoto, Y., Inoue, N., Ohkura, S., Uenoyama, Y., Maeda, K. I.
    • Organizer
      1^<st> world conference on kisspeptin signaling in the brain
    • Place of Presentation
      CORDOBA SPAIN
    • Related Report
      2008 Annual Research Report
  • [Presentation] 雌ラットにおける新生仔期のエストロジェン長期投与はパルス状LH分泌の抑制と弓_状メタスチンニューロン核のの減少を引き起こす2008

    • Author(s)
      稲本瑶子, 本間玲実, 上野山賀久, 前田麻希, 山田俊児, 井上直子, 大蔵聡, 前多敬一郎, 束村博子
    • Organizer
      第101回日本繁殖生物学会大会
    • Place of Presentation
      九州大学医学部百年講堂
    • Related Report
      2008 Annual Research Report
  • [Presentation] 交尾排卵動物スンクスにおけるメタスチンの排卵誘起効果2008

    • Author(s)
      井上直子, 上野山賀久, 大蔵聡, 束村博子, 前多敬一郎
    • Organizer
      第101回日本繁殖生物学会大会
    • Place of Presentation
      九州大学医学部百年講堂
    • Related Report
      2008 Annual Research Report
  • [Presentation] 雌ブタヘのkisspeptin-10静脈内投与による黄体形成ホルモン分泌刺激効果2008

    • Author(s)
      田島茂行, 柴田貴子, 河野建夫, 難波陽介, 大蔵聡, 上野山賀久, 束村博子, 前多敬一郎
    • Organizer
      第101回日本繁殖生物学会大会
    • Place of Presentation
      九州大学医学部百年講堂
    • Related Report
      2008 Annual Research Report
  • [Presentation] ウシKiss-1遺伝子の同定および視床下部におけるメタスチンニューロンの局在2008

    • Author(s)
      若林嘉浩, 大蔵聡, 上野山賀久, 高瀬健志, 東村博子, 前多敬一郎, 岡村裕昭
    • Organizer
      第101回日本繁殖生物学会大会
    • Place of Presentation
      九州大学医学部百年講堂
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヤギおよびブタ卵巣におけるメタスチンの局在2008

    • Author(s)
      平野隆之, 岡村裕昭, 上野山賀久, 束村博子, 前多敬一郎, 井上直子
    • Organizer
      第101回日本繁殖生物学会大会
    • Place of Presentation
      九州大学医学部百年講堂
    • Related Report
      2008 Annual Research Report
  • [Presentation] ラットにおけるメタスチン/キスペプチンに対する能動免疫による性腺機能の低下2008

    • Author(s)
      上野山賀久, 井上直子, 長谷川浩一, 冨川順子, 束村博子, 前多敬一郎
    • Organizer
      第101回日本繁殖生物学会大会
    • Place of Presentation
      九州大学医学部百年講堂
    • Related Report
      2008 Annual Research Report
  • [Presentation] 黄体形成ホルモン(LH)サージを制御するメタスチンニューロンの性差をもたらす新生仔期の性ステロイド2008

    • Author(s)
      本間玲実, 榊原基嗣, 岩田良香, 前田麻希, 山田俊児, 稲本瑶子, 上野山賀久, 前多敬一郎, 束村博子
    • Organizer
      第101回日本繁殖生物学会大会
    • Place of Presentation
      九州大学医学部百年講堂
    • Related Report
      2008 Annual Research Report
  • [Presentation] 生殖と摂食の制御に関わる脳内のエネルギーシグナル物質, ケトン体2008

    • Author(s)
      岩田衣世, 木下美香, 須崎直樹, 佐藤弘明, 上野山賀久, 束村博子, 前多敬一郎
    • Organizer
      第101回日本繁殖生物学会大会
    • Place of Presentation
      九州大学医学部百年講堂
    • Related Report
      2008 Annual Research Report
  • [Presentation] 未成熟雌ラツトにおける脳内メクスチン発現と黄体形成ホルモン(LH)分泌にたいするエストロジェンの抑制作用2008

    • Author(s)
      上野山賀久, 高瀬健志, 清水基道, 束村博子, 前多敬一郎
    • Organizer
      第101回日本繁殖生物学会大会
    • Place of Presentation
      九州大学医学部百年講堂
    • Related Report
      2008 Annual Research Report
  • [Presentation] シバヤギ視床下部弓状核のメタスチンニューロンはGnRHパルス発生機構に関与する2008

    • Author(s)
      大蔵聡, 高瀬健志, 松山秀一, 茂木一孝, 市丸徹, 上野山賀久, 森裕司, 束村博子, 前多敬一郎, 岡村裕昭
    • Organizer
      第35回日本神経内分泌学会第23回日本下垂体研究会合同学術集会
    • Place of Presentation
      政策研究大学院大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] Metastin/kisspeptin-GPR54 system regulating reproductive functions in mammals.2008

    • Author(s)
      束村博子, 山田俊児, 本間玲実, 稲本瑶子, 上野山賀久, 大蔵聡, 井上直子, 前多敬二郎
    • Organizer
      世界合同繁殖生物学会議
    • Place of Presentation
      コナ、ハワイ
    • Related Report
      2008 Annual Research Report
  • [Presentation] The absence in the neonatal androgen is essential for the presence of anteroventral periventricular metastin neurons and GnRH/LH surge system in the adult2008

    • Author(s)
      Homma, T., Uenoyama, Y., Maeda, M., Yamada, S., Iwata, K., Maeda. K. -I., Tsukamura, H.
    • Organizer
      世界合同繁殖生物学会議
    • Place of Presentation
      コナ、ハワイ
    • Related Report
      2008 Annual Research Report
  • [Presentation] Prolonged neonatal exposure to estrogen inhibits pulsatile LH release andestrous cyclicity in female rats probably via disruption of the. arcuate metastin/kisspeptin neurons.2008

    • Author(s)
      Inamoto, Y., Homma, T., Uenoyama, Y., Maeda, M., Yamada, S., Inoue. N., Ohkura, S., Maeda. K. -I, Tsukamura. H.
    • Organizer
      世界合同繁殖生物学会議
    • Place of Presentation
      コナ、ハワイ
    • Related Report
      2008 Annual Research Report
  • [Presentation] Brain ketone body sensing involved in the suppression of pulsatile luteinizing hormone release in female rats2008

    • Author(s)
      Iwata, K., Kinoshita, M., Susaki, N., Homma, T., Tsukamura, H., Maeda, K. -I.
    • Organizer
      世界合同繁殖生物学会議
    • Place of Presentation
      コナ、ハワイ
    • Related Report
      2008 Annual Research Report
  • [Presentation] 黄体形成ホルモン(LH)サージを誘起するエストロジェンの正のフィードバックを仲介するメタスチンニューロンの役割2008

    • Author(s)
      束村博子
    • Organizer
      日本畜産学会
    • Place of Presentation
      常磐大学
    • Related Report
      2007 Annual Research Report
  • [Presentation] 性成熟のタイミングを制御するメタスチンの発現調節機構2008

    • Author(s)
      上野山賀久
    • Organizer
      日本畜産学会
    • Place of Presentation
      常磐大学
    • Related Report
      2007 Annual Research Report
  • [Presentation] 性成熟のタイミングを制御するメタスチン/キスペプチン2007

    • Author(s)
      上野山賀久
    • Organizer
      第80回日本内分泌学会学術総会
    • Place of Presentation
      東京国際ファーラム
    • Related Report
      2007 Annual Research Report
  • [Presentation] 黄体形成ホルモン(LH)分泌の性差をもたらすメタスチン/キスペプチンニューロンの役割2007

    • Author(s)
      東村博子
    • Organizer
      第80回日本内分泌学会学術総会
    • Place of Presentation
      東京国際ファーラム
    • Related Report
      2007 Annual Research Report
  • [Presentation] 糖尿病による過食における脳内ケトン体センサーの役割2007

    • Author(s)
      岩田衣世
    • Organizer
      第34回日本神経内分泌学会
    • Place of Presentation
      ウェルシティ前橋
    • Related Report
      2007 Annual Research Report
  • [Presentation] ヒトメタスチン活性ペプチド(キスペプチンン10)は去勢雄ウシのLH分泌を促進する2007

    • Author(s)
      大蔵聡
    • Organizer
      日本下垂体研究会第22回学術集会
    • Place of Presentation
      湘南国際村センター国際会議場
    • Related Report
      2007 Annual Research Report
  • [Presentation] 上位細胞によるグルコース感知におけるAMPKの役割2007

    • Author(s)
      松本華代
    • Organizer
      日本下垂体研究会第22回学術集会
    • Place of Presentation
      湘南国際村センター国際会議場
    • Related Report
      2007 Annual Research Report
  • [Presentation] ラット後脳に存在する脂肪酸受容体GPR40のエネルギー感知機構における役割について2007

    • Author(s)
      坪井知恵
    • Organizer
      日本下垂体研究会第22回学術集会
    • Place of Presentation
      湘南国際村センター国際会議場
    • Related Report
      2007 Annual Research Report
  • [Presentation] Morphological basis for the regulation of GnRH release by metastin/kisspeptin neurons in the female rat brain2007

    • Author(s)
      Vutha Pheng
    • Organizer
      日本下垂体研究会第22回学術集会
    • Place of Presentation
      湘南国際村センター国際会議場
    • Related Report
      2007 Annual Research Report
  • [Presentation] 黄体形成ホルモン(LH)分泌の性差をもたらすメタスチンニューロンの役割2007

    • Author(s)
      東村博子
    • Organizer
      第100回日本繁殖生物学会大会・第12回日本生殖内分泌学会学術集会
    • Place of Presentation
      東京大学農学部キャンパス・弥生講堂
    • Related Report
      2007 Annual Research Report
  • [Presentation] Metastin/Kisspeptin Neuronal Projection in the Brain of Female Rats2007

    • Author(s)
      Vutha Pheng
    • Organizer
      第100回日本繁殖生物学会大会・第12回日本生殖内分泌学会学術集会
    • Place of Presentation
      東京大学農学部キャンパス・弥生講堂
    • Related Report
      2007 Annual Research Report
  • [Presentation] 視床下部弓状核メタスチンニューロンの黄体形成ホルモンサージの成立における役割について2007

    • Author(s)
      前多敬一郎
    • Organizer
      第100回日本繁殖生物学会大会・第12回日本生殖内分泌学会学術集会
    • Place of Presentation
      東京大学農学部キャンパス・弥生講堂
    • Related Report
      2007 Annual Research Report
  • [Presentation] 雌ラットの黄体形成ホルモン分泌におよぼすGalanin-like Peptideの影響2007

    • Author(s)
      上野山賀久
    • Organizer
      第100回日本繁殖生物学会大会・第12回日本生殖内分泌学会学術集会
    • Place of Presentation
      東京大学農学部キャンパス・弥生講堂
    • Related Report
      2007 Annual Research Report
  • [Presentation] ラット脳のエネルギー感知機構における脂肪酸受容体GPR40の役割について2007

    • Author(s)
      坪井知恵
    • Organizer
      第100回日本繁殖生物学会大会・第12回日本生殖内分泌学会学術集会
    • Place of Presentation
      東京大学農学部キャンパス・弥生講堂
    • Related Report
      2007 Annual Research Report
  • [Presentation] 生殖を制御する脳内グルコース感知におけるAMPKの役割2007

    • Author(s)
      松本華代
    • Organizer
      第100回日本繁殖生物学会大会・第12回日本生殖内分泌学会学術集会
    • Place of Presentation
      東京大学農学部キャンパス・弥生講堂
    • Related Report
      2007 Annual Research Report
  • [Presentation] シバヤギメタスチンニューロンに対するエストロジェン作用の形態学的解析2007

    • Author(s)
      岡村裕昭
    • Organizer
      第100回日本繁殖生物学会大会・第12回日本生殖内分泌学会学術集会
    • Place of Presentation
      東京大学農学部キャンパス・弥生講堂
    • Related Report
      2007 Annual Research Report
  • [Presentation] シバヤギ視床下部弓状核のメタスチンニューロンにおける多ニューロン発火活動の一過性上昇は黄体形成ホルモンのパルス状分泌に同期する2007

    • Author(s)
      茂木一孝
    • Organizer
      第100回日本繁殖生物学会大会・第12回日本生殖内分泌学会学術集会
    • Place of Presentation
      東京大学農学部キャンパス・弥生講堂
    • Related Report
      2007 Annual Research Report
  • [Presentation] パルス状GnRH/LH分泌成立機構におけるメタスチンニューロンの役割2007

    • Author(s)
      稲本瑶子
    • Organizer
      第100回日本繁殖生物学会大会・第12回日本生殖内分泌学会学術集会
    • Place of Presentation
      東京大学農学部キャンパス・弥生講堂
    • Related Report
      2007 Annual Research Report
  • [Presentation] 性成熟期のラット脳内におけるKiSS-1 mRNA発現の増加はエストロジェンにより制御される2007

    • Author(s)
      清水基道
    • Organizer
      第100回日本繁殖生物学会大会・第12回日本生殖内分泌学会学術集会
    • Place of Presentation
      東京大学農学部キャンパス・弥生講堂
    • Related Report
      2007 Annual Research Report
  • [Presentation] Stimulatory effect of galanin-like peptide (GALP) on luteinizing hormone release in female rats2007

    • Author(s)
      Y. UENOYAMA
    • Organizer
      Neuroscience 2007, the Socciety's 37th annual meeting
    • Place of Presentation
      San Diego Convention Center
    • Related Report
      2007 Annual Research Report
  • [Presentation] The role of arcuate metastin/kisspeptin neurons in regulation of pulsatile GnRH/LH secretion in the female rat2007

    • Author(s)
      Y. INAMOTO
    • Organizer
      Neuroscience 2007, the Socciety's 37th annual meeting
    • Place of Presentation
      San Diego Convention Center
    • Related Report
      2007 Annual Research Report
  • [Presentation] Expression of metastin/kisspeptin, a product of Kiss-1 gene, in the goat hypothalamus2007

    • Author(s)
      K. TAKASE
    • Organizer
      Neuroscience 2007, the Socciety's 37th annual meeting
    • Place of Presentation
      San Diego Convention Center
    • Related Report
      2007 Annual Research Report
  • [Presentation] Possible neuronal projections of the two populations of metastin/kisspeptin neurons in female rats2007

    • Author(s)
      V. PHENG
    • Organizer
      Neuroscience 2007, the Socciety's 37th annual meeting
    • Place of Presentation
      San Diego Convention Center
    • Related Report
      2007 Annual Research Report
  • [Presentation] 摂食と生殖をコントロールする生体のエネルギーセンサー2006

    • Author(s)
      前多敬一郎、束村博子
    • Organizer
      第141回日本獣医学会学術集会(平成18年春)(日本獣医師会・目本獣医学会連携大会)
    • Place of Presentation
      つくば国際会議場「エポカルつくば」
    • Related Report
      2009 Final Research Report
  • [Presentation] 摂食と生殖をコントロールする生体のエネルギーセンサー2006

    • Author(s)
      前多敬一郎、束村博子
    • Organizer
      第141回日本獣医学会学術集会(平成18年春)(日本獣医師会・日本獣医学会連携大会)
    • Place of Presentation
      つくば国際会議場「エポカルつくば」
    • Related Report
      2008 Self-evaluation Report
  • [Book] ヒトと動物の関係学 第2巻「家畜の文化」(秋篠宮文仁・林良博編)(バイオテクノロジーと家畜)2009

    • Author(s)
      前多敬一郎・束村博子
    • Total Pages
      280
    • Publisher
      岩波書店
    • Related Report
      2009 Final Research Report
  • [Book] ヒトと動物の関係学」第2巻「家畜の文化」(秋篠宮文仁, 林良博)(バイオテクノロジーと家畜)2009

    • Author(s)
      前多敬一郎・束村博子
    • Publisher
      岩波書店、東京
    • Related Report
      2008 Self-evaluation Report
  • [Book] バイオテクノロジーと家畜"「ヒトと動物の関係学」第2巻「家畜の文化」2009

    • Author(s)
      前多敬一郎, 束村博子
    • Total Pages
      20
    • Publisher
      岩波書店
    • Related Report
      2008 Annual Research Report
  • [Book] 生殖機能の神経内分泌メカニズムー内分泌と生命現象~シリーズ21世紀の動物科学~(、長濱嘉孝, 井口泰泉)2007

    • Author(s)
      大蔵聡、木下美香、上野山賀久、束村博子、前多敬一郎
    • Publisher
      培風館
    • Related Report
      2008 Self-evaluation Report
  • [Book] 生殖機能の神経内分泌メカニズム-内分泌と生命現象〜シリーズ21世紀の動物科学〜2007

    • Author(s)
      前多敬一郎
    • Total Pages
      36
    • Publisher
      培風館
    • Related Report
      2007 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://www.agr.nagoya-u.ac.jp/~hanshoku/

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.agr.nagoya-u.ac.jp/~hanshoku/

    • Related Report
      2008 Self-evaluation Report

URL: 

Published: 2006-04-01   Modified: 2016-04-21  

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