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Application of nanoLC/MS/MS to legal medicine

Research Project

Project/Area Number 18209025
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Legal medicine
Research InstitutionNagoya University (2007-2009)
Fujita Health University (2006)

Principal Investigator

ISHII Akira  Nagoya University, 大学院・医学系研究科, 教授 (30252175)

Co-Investigator(Kenkyū-buntansha) KANEKO Rina  名古屋大学, 大学院・医学系研究科, 助教 (70367697)
HIRAOKA Kenzo  山梨大学, クリーンエネルギーセンター, 特任教授 (80107218)
HIRATA Yukari  藤田保健衛生大学, 医学部, 助教 (50156676)
HAMAJIMA Makoto  藤田保健衛生大学, 医学部, 助教 (20189608)
TAKAMIZAWA Jun  山梨大学, クリーンエネルギーセンター, 科学技術振興研究員 (80377605)
Project Period (FY) 2006 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥47,970,000 (Direct Cost: ¥36,900,000、Indirect Cost: ¥11,070,000)
Fiscal Year 2009: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2008: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2007: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
Fiscal Year 2006: ¥27,950,000 (Direct Cost: ¥21,500,000、Indirect Cost: ¥6,450,000)
Keywords高速液体クロマトグラフィー / 質量分析 / エレクトロスプレー / 大気圧化学イオン化 / ナノスケールLC / プローブエレクトロスプレー / マッシブクラスターイオン衝撃 / SIMS / UPLC / ナノスケールIC / レーザースプレー
Research Abstract

High performance-liquid chromatography/tandem mass spectrometers (LC/MS/MS) are widely used not only in biology, but also in forensic sciences. In this project, we have developed an ultrasensitive method for determining poisons and pharmaceuticals using a nanoscale LC (nanoLC)/MS/MS. Also, new ionization methods for LC/MS have been developed, and some methods were applied to legal medicine.

Report

(6 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report   Self-evaluation Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (98 results)

All 2010 2009 2008 2007 2006

All Journal Article (59 results) (of which Peer Reviewed: 51 results) Presentation (23 results) Book (5 results) Patent(Industrial Property Rights) (11 results) (of which Overseas: 3 results)

  • [Journal Article] High-throughput of theophyline and caffeine in human serum by conventional liquid chromatography-mass spectrometry.2009

    • Author(s)
      Arinobu T, Kaneko R (6番目), Ishii, A (7番目), 他8名
    • Journal Title

      Forensic Toxicol 27

      Pages: 1-7

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Simultaneous analysis of aconitine, mesaconitine, hypaconitine, and jesaconitine in whole blood by LC-MS-MS using a new polymer column.2009

    • Author(s)
      Hattori H, Hirata Y, Kaneko R (4番目), Ishii A (6番目), 他4名
    • Journal Title

      Forensic Toxicol 27

      Pages: 7-11

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Rapid detection of drugs in biofluids using atomospheric pressure chemi/chemical ionization mass spectrometry.2009

    • Author(s)
      Chen LC, Hiraoka K (6番目), 他4名
    • Journal Title

      Rapid Commun. Mass Spectrom 23

      Pages: 333-339

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Depth profiling of polystyrene using charged water drop impact2009

    • Author(s)
      Y Sakai, Y Iijima, et al.
    • Journal Title

      J.Surface Analysis 15

      Pages: 41-46

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rapid detection of drugs biofluids using atomospheric pressure chemi/chemical ionization mass spectrometry2009

    • Author(s)
      LC Chen, Y Hashimoto, et al.
    • Journal Title

      Rapid Commun.Mass Spectrom. 23

      Pages: 333-339

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mass spectrometric detection of gaseous hydrogen peroxide in the ambient air using dielectric barrier discharge as an excitation source2009

    • Author(s)
      LC Chen, A Suzuki, et al.
    • Journal Title

      Chemistry Letters 38

      Pages: 520-521

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct and real-time surface analysis and imaging of biological samples by probe electrospray2009

    • Author(s)
      平岡賢三, LC Chen, et al.
    • Journal Title

      J.Surface Analysis 15

      Pages: 279-282

    • NAID

      130007498541

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Surface characterization of polymethylmetacrylate bombarded by charged water droplets2009

    • Author(s)
      平岡賢三, R Takahashi, et al.
    • Journal Title

      J.Vac.Sci.Technol. 27

      Pages: 748-753

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Study on the redox reactions for organic dyes and S-nitrosylated peptide in electrospray droplet impact2009

    • Author(s)
      浅川大樹, 平岡賢三
    • Journal Title

      J.Mass Spectrom. 44

      Pages: 461-465

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 脱離イオン化質量分析法による難溶性顔料の分析2009

    • Author(s)
      浅川大樹, 久高一郎, 平岡賢三
    • Journal Title

      質量分析 57

      Pages: 15-22

    • NAID

      10024837235

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The analysis of industrial synthetic polymers by electrospray dropletimpact/secondary ion mass spectrometry2009

    • Author(s)
      浅川大樹, LC Chen, et al.
    • Journal Title

      J.Mass Spectrom. 44

      Pages: 945-951

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Determination of dynamic ranges for quantitative analysis using electrospray droplet impact ionization matrix-assisted laser desorption Ionization2009

    • Author(s)
      浅川大樹, Y hashimoto, et al.
    • Journal Title

      J.Mass Spectrom.Soc.Japan 57

      Pages: 81-87

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Shallow surface etching of organic and inorganic compounds by electrospray droplet impact2009

    • Author(s)
      平岡賢三, Y Sakai, et al.
    • Journal Title

      Applied Surface Sci. 255

      Pages: 8947-8952

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of polysilanes by tunneling reactions of H atoms with solid Si_2H_6 at 10K2009

    • Author(s)
      N Sogoshi, S Sato, et al.
    • Journal Title

      Chemistry Letters 38

      Pages: 656-662

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] X-ray photoelectron spectroscopy analysis of organic materials etched by charged water droplet impact2009

    • Author(s)
      Y Sakai, Y Iijima, et al.
    • Journal Title

      J.Vac.Sci.Tecxhnol.A 27

      Pages: 743-747

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 質量分析装置のためのイオン化法 次世代を担う新たなイオン化法2009

    • Author(s)
      Y Sakai, Y Iijima, et al.
    • Journal Title

      ぶんせき

      Pages: 743-747

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Simultaneous analysis of aconitine, mesaconitine, hypaconitine, and jesaconitine in whole blood by LC-MS-MS using a new polymer column2009

    • Author(s)
      Hattori H, Hirata Y, et.al.
    • Journal Title

      Forensic Toxicol 27

      Pages: 7-11

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] レーザースプレー質量分析が可能にした生体高分子複合体の結合親和性の定量的な解析2009

    • Author(s)
      明石知子, 史向国, 他
    • Journal Title

      質量分析 56

      Pages: 185-161

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High-throughput determination of theophylline and caffeine in human serum by conventional liquid chromatographymass spectrometery.2009

    • Author(s)
      Arinobu T, Hattori H, et al.
    • Journal Title

      Forensic Toxicol. 27

      Pages: 1-6

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Simultaneous analysis of aconitine, mesaconitine, hypaconitine, and jesa conitine in whole blood by LC-MS-MS using a new polymer column.2009

    • Author(s)
      Hattori H, Hirata Y, et al.
    • Journal Title

      Forensic Toxicol. 27

      Pages: 7-11

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Au-assisted visible laser of mass spectrometry.2009

    • Author(s)
      Chen LC. Mori K, et al.
    • Journal Title

      Int. J. Mass Spectrom. 279

      Pages: 41-46

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Negative-mode MALDI mass spectrometry for the analysis of pigments using tetrathiafulvalene as a matrix.2008

    • Author(s)
      Asakawa D, Chen LC, Hiraoka K
    • Journal Title

      J. Mass Spectrom 43

      Pages: 1217-1222

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ambient imaging mass spectrometry by electrospray ionization using solid needle as sampling probe.2008

    • Author(s)
      Chen LC, Hiraoka K (11番目), 他9名
    • Journal Title

      J. Mass Spectrom 44

      Pages: 1479-1477

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 新しい質量分析技術の法医学領域への応用2008

    • Author(s)
      石井晃, 金子理奈, 平田ゆかり, 浜島誠
    • Journal Title

      質量分析 56

      Pages: 131-138

    • NAID

      10021086864

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Negative-mode MALDI mass spectrometry for the analysis of pigments using tetrathiafulvalene as a matrix2008

    • Author(s)
      Asakawa D, Chen LC, Hiraoka K
    • Journal Title

      J. Mass Spectrom 43

      Pages: 1217-1222

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] 新しい質量分析技術の法医学領域への応用2008

    • Author(s)
      石井晃, 金子理奈, 他
    • Journal Title

      質量分析 56

      Pages: 131-138

    • NAID

      10021086864

    • Related Report
      2008 Annual Research Report 2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] 薬毒物分析2008

    • Author(s)
      石井晃
    • Journal Title

      現代医学 56

      Pages: 169-173

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Application of probe electrospray to direct ambient analysis of biological Samples.2008

    • Author(s)
      Chen LC, Nishidate K, et al.
    • Journal Title

      Rapid Commun. Mass Spectrom. 22

      Pages: 2366-2374

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characteristics of probe electrospray generated from a solid needle. .2008

    • Author(s)
      Chen LC, Nishidate K, et al.
    • Journal Title

      J. Phys. Chem. 112

      Pages: 11164-11170

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Negative-mode MALDI mass spectrometry for the analysis of pigments using tetrathiafulvalene as a matrix.2008

    • Author(s)
      Asakawa D, Chen LC, HiraokaK
    • Journal Title

      J. Mass Spectrom. 43

      Pages: 1217-2222

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Energy dependence of projectiles on ion formation in electrospray droplet impact SIMS. .2008

    • Author(s)
      Asakawa D, Mori K, Hiraoka K
    • Journal Title

      Appl. Surf. Sci. 255

      Pages: 1217-1222

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Extremely smooth surface etching by giant clusterion impact.2008

    • Author(s)
      Sakai Y, Iijima Y, et al.
    • Journal Title

      J. Surf. Anal. 14

      Pages: 466-468

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Auger crater edge profiling by water droplet impact.2008

    • Author(s)
      Sakai Y, Iijima Y, Hiraoka K
    • Journal Title

      J. Surf. Anal. . 15

      Pages: 172-176

    • NAID

      130007498913

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular-level etching by electrospray droplet impact.2008

    • Author(s)
      Sakai Y, Iijima Y, et al.
    • Journal Title

      Surf. Interface Anal. 40

      Pages: 1716-1718

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Thermal unfolding of proteins probed by laser spray mass spectrometry2008

    • Author(s)
      Shi X, Takamizawa A, et al.
    • Journal Title

      Rapid Commun. Mass Spectrom. 22

      Pages: 1430-1436

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A comparison EDI with solvent-free MALDI and LDI for the analysis of organic pigments2008

    • Author(s)
      Kudaka I, Asakawa D, et al.
    • Journal Title

      J. Mass Spectrom. 43

      Pages: 436-446

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cluster ion formation of alkali halides by electrospray droplet impact2008

    • Author(s)
      Mori K, Hiraoka K
    • Journal Title

      Int. J. Mass Spectrom. 269

      Pages: 95-100

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gas-phase ion/molecule reactions in C_2F_42008

    • Author(s)
      HIraoka K, Michizuki N, et al.
    • Journal Title

      Int. J. Mass Spectrom. 272

      Pages: 22-28

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Measurement of sugars using the laser spray technique with a gold capillary2008

    • Author(s)
      Takamizawa A, Maeda H, et al.
    • Journal Title

      Rapid Commun. Mass Spectrom. 22

      Pages: 2453-2456

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rapid Analysis of sertraline, fluvoxamine, and paroxetine in serum specimens by LC-MS-MS using a new polymer column.2007

    • Author(s)
      Hattori H, Ishii A (7番目), 他7名
    • Journal Title

      Forensic Toxicol 25

      Pages: 100-103

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of probe electrospray using a solid needle. Rapid Commun.2007

    • Author(s)
      Hiraoka K, 他4名
    • Journal Title

      Mass Spectrom 21

      Pages: 3139-3144

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of probe electrospray using a solid needle2007

    • Author(s)
      Hiraoka K, NIshidate K, et.al
    • Journal Title

      Rapid Commun. Mass Spectrom 21

      Pages: 3139-3144

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Rapid analysis of seretraline, fluvoxamine, and paroxetine in serum specimen by LC-MS-MS using a new polymer column2007

    • Author(s)
      Hattori H, Ito K, et al.
    • Journal Title

      Foresic Toxicol. 25

      Pages: 100-103

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visible-laser desorption/ionization on gold nanostructures2007

    • Author(s)
      Chen LC, Yoneyama J, et al.
    • Journal Title

      J. Mass Spectrom. 42

      Pages: 346-353

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Study on ion formation in electrospray droplet impact secondary ion mass spectrometry2007

    • Author(s)
      Asakawa D, Fujimaki S, et al.
    • Journal Title

      Rapid Commun. Mass Spectrom. 21

      Pages: 1579-1586

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Denaturation of α-lactoalbumin and ubiquitin studied by electrospray and laser spray2007

    • Author(s)
      Nakamura M, Takamizawa A, et al.
    • Journal Title

      Rapid Commun. Mass Spectrom. 21

      Pages: 1635-1643

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visible laser desorption/ionization mass spectrometry using gold nanorods2007

    • Author(s)
      Chen LC, Ueda T, et al.
    • Journal Title

      J. Phys. Chem. C 111

      Pages: 2409-2415

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Thermochemical stabilities of the gas-phase cluster ions with rare gas atoms2007

    • Author(s)
      Wada A, Kikkawa A, et al.
    • Journal Title

      Int. J. Mass Spectrom. 267

      Pages: 284-287

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of probe electrospray using a solid needle2007

    • Author(s)
      Hiraoka K, Nishidate K, et al.
    • Journal Title

      Rapid Commun. Mass Spectrom. 21

      Pages: 3139-3144

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Matrix-assissted laser desorption/ionization mass spectrometry using a visible laser2007

    • Author(s)
      Chen LC, Asakawa D, et al.
    • Journal Title

      Rapid Commun. Mass Spectrom. 21

      Pages: 4129-4134

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sensitive analysis of aconitine, hypaconitine, mesaconitine, and jesaconitine in human body fluids and Aconitum tubers by LC/ESI-TOF-MS.2006

    • Author(s)
      Kaneko R, Hamajima M (4番目), Hirata Y (5番目), Ishii A (8番目), 他4名
    • Journal Title

      J. Mass Spectrom 41

      Pages: 810-814

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Pipette tip solid-phase extraction and gas chromatography-mass spectrometry for the determination of mequitazine in human plasma.2006

    • Author(s)
      Kumazawa T, Ishii A (6番目), 他6名
    • Journal Title

      Talanta 70

      Pages: 474-478

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sensitive analysis of aconitine, hypaconitine, mesaconitine, and jesaconitine in human body fluids and Aconitum tubers by LC/ESI-TOF-MS2006

    • Author(s)
      Kaneko R, Ishii A, et.al
    • Journal Title

      J. Mass Spectrom. 41

      Pages: 810-814

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Sensitive analysis of aconitine, Hypaconitine, mesaconitine, and jesaconitine in human body fluids and Aconitum tubers by LC/EST-TOF-MS2006

    • Author(s)
      Kaneko R, Ishii A., et al.
    • Journal Title

      J. Mass spectrom. 41

      Pages: 810-814

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Pipette tip solid-phase extraction and gas chromatography-mass for the determination of mequitazine in human plasma2006

    • Author(s)
      Kumazawa T, Ishii A., et al.
    • Journal Title

      Talanta 70

      Pages: 474-478

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Electrosprayed droplet impact/secondary ion mass spectrometry2006

    • Author(s)
      Hiraoka K., et al.
    • Journal Title

      Eur. Phys. j. D 38

      Pages: 225-229

    • NAID

      10019487326

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Solid-phase reactions of D with CN to form DNC and DCN at cryogenic temperatures2006

    • Author(s)
      Hiraoka K., et al.
    • Journal Title

      Astrophys. J. 643

      Pages: 917-922

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Fundamental aspects of electrospray droplet impact/SIMS2006

    • Author(s)
      Hiraoka K., et al.
    • Journal Title

      J. Mass Spectrom. 41

      Pages: 894-902

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Atmospheric pressure Penning ionization of aliphatic hydrocarbons2006

    • Author(s)
      Hiraoka K., et al.
    • Journal Title

      Rapid Commun. Mass Spectrom. 20

      Pages: 3213-3222

    • Related Report
      2006 Annual Research Report
  • [Presentation] 高度の脂肪肝と急性尿細管壊死を伴う、劇症I型糖尿病の可能性が考えられた症例2009

    • Author(s)
      石井晃, 吉本高士, 水谷達志, 金子理奈
    • Organizer
      第31回 日本法医学会学術中部地方集会
    • Place of Presentation
      ホテルコンコルド浜松, 浜松
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Shallow depth profiling by electrospray droplet impact2009

    • Author(s)
      K Hiraoka
    • Organizer
      SIMS XVII Conference
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2009-09-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] Ambient imaging and profiling mass spectrometry by electrospray imaging using a solid needle as sampling probe2009

    • Author(s)
      K Hiraoka
    • Organizer
      University of Alberta
    • Place of Presentation
      Alberta, Canada
    • Year and Date
      2009-09-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] UPLC/MS (/MS) を用いたヒト体液中向精神薬の一斉分析2009

    • Author(s)
      石井晃, 金子理奈, 他
    • Organizer
      第34回 日本医用マススペクトル学会
    • Place of Presentation
      近畿大学, 大阪
    • Year and Date
      2009-09-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] モノリスカラムを用いたバックフラッシュカラムスイッチングLC/MSによる血中ネオフィリンの超迅速分析2009

    • Author(s)
      有信哲哉, 他
    • Organizer
      第34回 日本医用マススペクトル学会
    • Place of Presentation
      近畿大学, 大阪
    • Year and Date
      2009-09-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] Shallow depth profiling by electrospray droplet/SIMS2009

    • Author(s)
      Hiraoka K
    • Organizer
      SIMS XVII Conference
    • Place of Presentation
      Bremen, Germany
    • Year and Date
      2009-09-03
    • Related Report
      2009 Final Research Report
  • [Presentation] Fundamentals and application of electrospray droplet/SIMS2009

    • Author(s)
      K Hiraoka, et al.
    • Organizer
      18th International Mass Spectrometry Conference
    • Place of Presentation
      Bremen, Germany
    • Year and Date
      2009-09-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] A rapid and simultaneous analysis of psycho- pharmaceuticals in human body fluids with ultraperformance liquid chromatography tandem mass spectrometry.2009

    • Author(s)
      Kaneko R, Ishii A (7番目), 他6名
    • Organizer
      he 47 th Annual Meeting of the International Association of Forensic Toxiocologists Conference
    • Place of Presentation
      Geneva, Switzerland
    • Year and Date
      2009-08-26
    • Related Report
      2009 Final Research Report
  • [Presentation] A rapid and simultaneous analysis of psychopharmaceuticals in human body fluids with ultra-performance liquid chromatography-tandem mass spectrometry2009

    • Author(s)
      金子理奈, et al.
    • Organizer
      47th Annual Meeting of the Intrenational Association of Forensic Toxicologists Conference
    • Place of Presentation
      Geneva, Switzerland
    • Year and Date
      2009-08-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] HTLV-I感染を背景とした免疫不全が想定された多発性膿瘍の一例2009

    • Author(s)
      石井晃, 他
    • Organizer
      第93次 日本法医学会学術全国集会
    • Place of Presentation
      千里ライフサイエンスセンター, 大阪
    • Year and Date
      2009-05-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] Simultaneous analyses of 17 volatile organic compounds by cryogenic-oven-trapping gas chromatography- mass spectrometry.2008

    • Author(s)
      Kaneko R, Hirata Y, et. al
    • Organizer
      The 7 th International Symposium of Advances in Legal Medicine
    • Place of Presentation
      大阪
    • Year and Date
      2008-09-04
    • Related Report
      2009 Final Research Report
  • [Presentation] Simultaneous analyses of 17 volatile organic compounds by cryogenic-oven-trapping gas chromatography- mass spectrometry2008

    • Author(s)
      Kaneko R, Hirata Y, et.al
    • Organizer
      The 7^<th> International Symposium of Advances in Legal Medicine
    • Place of Presentation
      大阪
    • Year and Date
      2008-09-04
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] Simultaneous analyses of 17 volatile organic compounds by cryogenic-Oven-trapping gas chromatographymass spectrometry2008

    • Author(s)
      Kaneko R, Hirata Y, et al.
    • Organizer
      The 7^<th> International Symposium of Advances in Legal Medicine
    • Place of Presentation
      大阪
    • Year and Date
      2008-09-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 血清中SNRI, DNRI及びNRIのLC/MS/MSによる迅速分析2008

    • Author(s)
      服部秀樹, 金子理奈(3番目), 石井晃(7番目), 他6名
    • Organizer
      日本法中毒学会第27年会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-14
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 血清中SNRI2008

    • Author(s)
      服部秀樹, 伊藤健次郎, 他
    • Organizer
      DNRI及びNRIのLC/MS/MSによる迅速分析日本法中毒学会第27年会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-14
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] Sensitive analysis of volatile compounds by cryogenic-oven- trapping gas chromatography-mass spectrometry.2008

    • Author(s)
      Kaneko R, Hirata Y, Hamajima M, Ishii A (6番目), 他3名
    • Organizer
      The 46th TIAFT
    • Place of Presentation
      La Martinique. French
    • Year and Date
      2008-06-04
    • Related Report
      2009 Final Research Report
  • [Presentation] Sensitive analysis of volatile compounds by cryogenic-oven- trapping gas chromatography-mass spectrometry2008

    • Author(s)
      Kaneko R, Hirata Y, et.al.
    • Organizer
      The 46^<th> TIAFT
    • Place of Presentation
      La Martinique
    • Year and Date
      2008-06-04
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] Sensitive analysis of volatile compounds by cryogenic-oven-trapping gas Chromatographymass spectrometry2008

    • Author(s)
      Kaneko R, Hirata Y, et al.
    • Organizer
      The 46^<th> TIAFT
    • Place of Presentation
      La Martinique
    • Year and Date
      2008-06-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 低温オーブントラッピングGC/MSによる揮発性有機化合物の一斉分析2008

    • Author(s)
      金子理奈, 平田ゆかり, 他
    • Organizer
      第92次日本法医学会総会
    • Place of Presentation
      長崎
    • Year and Date
      2008-04-24
    • Related Report
      2008 Annual Research Report
  • [Presentation] 低温オーブントラッピングGC/MSを用いた揮発性有機化合物の一斉分析2007

    • Author(s)
      金子理奈、平田ゆかり, 他
    • Organizer
      第32回日本医用マススペクトル学会
    • Place of Presentation
      京都
    • Year and Date
      2007-09-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] 新しい質量分析技術の法医学領域への応用2007

    • Author(s)
      石井晃
    • Organizer
      第34回BMSカンファレンス
    • Place of Presentation
      鳥羽
    • Year and Date
      2007-07-10
    • Related Report
      2009 Final Research Report 2008 Self-evaluation Report 2007 Annual Research Report
  • [Presentation] レーザースプレーイオン化法によるヒト体液中向精神薬の高感度分析2007

    • Author(s)
      石井晃, 金子理奈平田ゆかり, 浜島誠, 他3名
    • Organizer
      第91次日本法医学会総会
    • Place of Presentation
      秋田
    • Year and Date
      2007-05-18
    • Related Report
      2009 Final Research Report 2008 Self-evaluation Report 2007 Annual Research Report
  • [Presentation] 第二世代抗アレルギー剤のLC/MS/MSによる血中からの検出2007

    • Author(s)
      服部秀樹、岩井雅枝, 他
    • Organizer
      第91次日本法医学会総会
    • Place of Presentation
      秋田
    • Year and Date
      2007-05-18
    • Related Report
      2007 Annual Research Report
  • [Book] 光近接場と質量分析. 「光科学研究の最前線2」(強光子場科学研究懇談会編)2009

    • Author(s)
      平岡賢三
    • Total Pages
      139
    • Related Report
      2009 Final Research Report
  • [Book] 光近接場と質量分析「光科学研究の最前線2」2009

    • Author(s)
      平岡賢三
    • Total Pages
      258
    • Publisher
      強光子場科学研究懇談会
    • Related Report
      2009 Annual Research Report
  • [Book] Surface ionization and its application to GC-MS.(In: Encyclopedia of Mass Spectrometry)2006

    • Author(s)
      Ishii A, Suzuki O, Katsumata Y
    • Related Report
      2009 Final Research Report
  • [Book] Section 8-2-04. Surface ionization and its application to GC-MS (Vol.8 (ed. Wilfred Niessen))2006

    • Author(s)
      Ishii A, Suzuki O, Katsumata Y
    • Publisher
      In : Encyclopedia of Mass Spectrometry
    • Related Report
      2008 Self-evaluation Report
  • [Book] Encyclopedia of Mass Spectrometry, Vol. 8 (ed. Wilfred Niessen)2006

    • Author(s)
      Ishii A., et al.
    • Total Pages
      1068
    • Publisher
      Elsevier Science Ltd.
    • Related Report
      2006 Annual Research Report
  • [Patent(Industrial Property Rights)] イオン化装置およびイオン化分析装置2010

    • Inventor(s)
      平岡賢三
    • Industrial Property Rights Holder
      山梨大学
    • Industrial Property Number
      2010-029157
    • Filing Date
      2010-02-12
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Patent(Industrial Property Rights)] 過酸化水素の検出方法および装置2010

    • Inventor(s)
      平岡賢三
    • Industrial Property Rights Holder
      山梨大学
    • Filing Date
      2010-02-10
    • Related Report
      2009 Final Research Report
  • [Patent(Industrial Property Rights)] 帯電液滴エッチングを用いた試料表面汚染除去方法及び装置2010

    • Inventor(s)
      平岡賢三
    • Industrial Property Rights Holder
      山梨大学
    • Industrial Property Number
      2010-001947
    • Filing Date
      2010-01-07
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Patent(Industrial Property Rights)] 過酸化水素の検出方法および装置2010

    • Inventor(s)
      平岡賢三
    • Industrial Property Rights Holder
      山梨大学
    • Filing Date
      2010-02-10
    • Related Report
      2009 Annual Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] エレクトロスプレーによるイオン化法および装置、ならびに分析方法および装置2009

    • Inventor(s)
      平岡賢三
    • Industrial Property Rights Holder
      山梨大学
    • Industrial Property Number
      2009-278458
    • Filing Date
      2009-12-08
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Patent(Industrial Property Rights)] 探針を用いたイオン化方法及び装置、ならびに分析方法および装置2009

    • Inventor(s)
      平岡賢三
    • Industrial Property Rights Holder
      山梨大学
    • Filing Date
      2009-10-19
    • Related Report
      2009 Final Research Report
  • [Patent(Industrial Property Rights)] イオン化分析方法及び装置2009

    • Inventor(s)
      平岡賢三
    • Industrial Property Rights Holder
      山梨大学
    • Filing Date
      2009-06-04
    • Related Report
      2009 Final Research Report
  • [Patent(Industrial Property Rights)] イオン化分析方法及び装置2009

    • Inventor(s)
      平岡賢三, 他
    • Industrial Property Rights Holder
      山梨大学
    • Filing Date
      2009-06-04
    • Related Report
      2009 Annual Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] 探針を用いたイオン化方法及び装置、ならびに分析方法および装置2009

    • Inventor(s)
      平岡賢三
    • Industrial Property Rights Holder
      山梨大学
    • Filing Date
      2009-10-19
    • Related Report
      2009 Annual Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] イオン化法及び装置2008

    • Inventor(s)
      平岡賢三
    • Industrial Property Rights Holder
      山梨大学
    • Industrial Property Number
      2008-008247
    • Filing Date
      2008-01-17
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Patent(Industrial Property Rights)] イオン化法および装置2008

    • Inventor(s)
      平岡賢三
    • Industrial Property Rights Holder
      山梨大学
    • Filing Date
      2008-01-17
    • Related Report
      2008 Self-evaluation Report

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Published: 2006-04-01   Modified: 2016-04-21  

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