|Budget Amount *help
¥49,140,000 (Direct Cost: ¥37,800,000、Indirect Cost: ¥11,340,000)
Fiscal Year 2009: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Fiscal Year 2008: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
Fiscal Year 2007: ¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
Fiscal Year 2006: ¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
We identified a transcription factor p63 as the potent inducer of SOX6, a member of SOX family essential for chondrocyte generation and differentiation. In this study, we revealed that p63 was extensively expressed in chondrocytes, that p63 was indispensable for development of limb cartilage, and that p63 played important roles in every differentiation stages of chondrocytes.