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The wound healing mechanisms and regenerative therapy in dental pulp and periapical tissues

Research Project

Project/Area Number 18209057
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Conservative dentistry
Research InstitutionKyushu University

Principal Investigator

YOSHIMINE Yoshito  Kyushu University, 歯学研究院, 准教授 (80183705)

Co-Investigator(Kenkyū-buntansha) KITAMURA Chiaki  九州歯科大学, 歯学部, 准教授 (50265005)
SHIBA Hideki  広島大学, 歯学研究院, 准教授 (60260668)
KAWASHIMA Nobuyuki  東京医科歯科大学, 医歯(薬)総合研究科, COE特任教員 (60272605)
DOKUDA Masayuki  鹿児島大学, 医学部・歯学部附属病院, 講師 (20253891)
TAKASHIBA Syogo  岡山大学, 医歯(薬)総合研究科, 教授 (50226768)
MAEDA Katumasa  九州大学, 歯学研究院, 教授 (00117243)
YOKOSE Satoshi  奥羽大学, 歯学部, 教授 (90245803)
SYOJI Shigeru  東北大学, 大学病院, 講師 (10142986)
SAITO Takashi  北海道医療大学, 歯学部, 教授 (40265070)
KUNIMATSU Kazushi  岩手医科大学, 歯学部, 教授 (20170011)
Project Period (FY) 2006 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥45,110,000 (Direct Cost: ¥34,700,000、Indirect Cost: ¥10,410,000)
Fiscal Year 2008: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
Fiscal Year 2007: ¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2006: ¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Keywords歯髄 / 根尖部歯周組織 / 創傷治癒 / 再生療法
Research Abstract

歯の神経(歯髄)や根の先の周りの骨(根尖部歯周組織)に異常が生じる疾患において、これらの傷害が治癒するメカニズムを詳細に調べることで、従来とは異なる新しい治療法の確立に向けた包括的な研究を試みた。その結果、歯髄・象牙質・骨組織の再生への足がかりとなるデータを多く得ることができた。今後更に研究を発展させることで、臨床応用の可能な治療法の開発へと繋がるものと期待される。

Report

(4 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (97 results)

All 2009 2008 2007 2006

All Journal Article (41 results) (of which Peer Reviewed: 40 results) Presentation (52 results) Book (4 results)

  • [Journal Article] Neodymium-Doped Yttrium-Aluminium-Garnet Laser Irradiation Abolishes the Increase in Interleukin-6 Levels Caused by Peptidoglycan Through the p38 Mitogen-Activated Protein Kinase Pathway in Human Pulp Cells2009

    • Author(s)
      Hideki Shiba, 他7名
    • Journal Title

      Journal of Endodontics (in press)

    • NAID

      120001700424

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neodymium-Doped Yttrium-Aluminium-Garnet Laser Irradiation Abolishes the Increase in Interleukin-6 Levels Caused by Peptidoglycan Through the p38 Mitogen-Activated Protein Kinase Pathway in Human Pulp Cells.2009

    • Author(s)
      Hideki Shiba, Hidehiro Tsuda, 他6名
    • Journal Title

      Journal of Endodontics 35

      Pages: 373-376

    • NAID

      120001700424

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of Notch-Signalling-related Genes in Normal and Differentiating Rat Dental Pulp Gells2009

    • Author(s)
      Sun H, Kawashima N, Xu J, Takahashi S, Suda H
    • Journal Title

      AEJ in press

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Contemporary Meaning of Intracanal Medicaments2009

    • Author(s)
      Kawashima N, Wadachi R, Yeng T, Parashos P, Suda H
    • Journal Title

      IDJ in press

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Formation of Dentinal Bridge on Surface of Regenerated Dental Pulpin Dentin Defects by Controlled Release of Fibroblast Growth Factor-2 from Gelatin Hydrogels.2009

    • Author(s)
      Ishimatsu H
    • Journal Title

      Journal of Endodontics in press

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ozonated Water Improves Lipopolysaccharide -Induced Responses of Odontoblast-like Cell Line.2009

    • Author(s)
      Noguchi F
    • Journal Title

      Journal of Endodontics in press

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 歯科治療へのアロマテラピー応用が患者不安の改善に与える効果.2009

    • Author(s)
      吉田真理
    • Journal Title

      アロマテラピー学雑誌 9

      Pages: 47-54

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The role of water channel aquaporin 3 in the mechanism of TNF-a-mediated proinflammatory events : implication in periodontal inflammation2008

    • Author(s)
      Tancharoen S., Tokuda M., 他8名
    • Journal Title

      Journal of Cellular Physiology 217巻

      Pages: 338-349

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Wound Healing Process of Injured Pulp Tissues with Emdogain Gel2008

    • Author(s)
      Hikaru Kaida, Katsumasa Maeda, 他2名
    • Journal Title

      Journal of Endodontics 34巻

      Pages: 26-30

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 培養歯髄細胞の結節形成現象とアポトーシスの関連性について2008

    • Author(s)
      八重柏隆、國松和司, 他3名
    • Journal Title

      日本歯科保存学会誌 51巻

      Pages: 99-104

    • NAID

      110007151212

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 炭酸ガスレーザーによる漂白後エナメル質表面へのハイドロキシアパタイト融着の試み2008

    • Author(s)
      菊井徹哉、横瀬敏志, 他2名
    • Journal Title

      日本レーザー歯学会誌 19巻

      Pages: 78-83

    • NAID

      130003757806

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 円錐型チップを装着したEr : YAGレーザーの根管内スミヤー層除去効果2008

    • Author(s)
      吉嶺嘉人, 他6名
    • Journal Title

      日本歯科保存学会誌 51巻

      Pages: 156-162

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] T Cell Response Mediated by Myeloid Cell-Derived IL-12 Is Responsible for Porphyromonas gingivalis-Induced Periodontitis in IL-10-Deficient Mice2008

    • Author(s)
      Sasaki H, Suzuki N, Kent R, Kawashima N, Takeda J, Stashenko P
    • Journal Title

      Journal of Immunology 180

      Pages: 6193-6198

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Amelogenin positive cells scattered in the interstitial component of odontogenic fibromas2008

    • Author(s)
      Kabasawa Y, Nagumo K, 他6名
    • Journal Title

      J. Clin. Pathol. 61

      Pages: 851-855

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 上顎第一大臼歯・近心第二根管について-超音波チップと実体顕微鏡で処置した症例-2008

    • Author(s)
      中野貴和子 川島伸之 須田英明
    • Journal Title

      日本歯科保存学会誌 51

      Pages: 456-470

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 臨床をシミュレートした環境下でのNi-Tiファイルによる根管形成に与える臨床経験の影響 第1報 湾曲の少ない根管における根管形成所要時間と根管壁の評価.2008

    • Author(s)
      永吉雅人
    • Journal Title

      日本歯内療法学会誌 29

      Pages: 113-118

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 難治性口腔顔面痛への直線偏光近赤外線の効果についての検討.2008

    • Author(s)
      坂本英治
    • Journal Title

      日本レーザー治療学会誌 6

      Pages: 22-25

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 培養歯髄細胞の結節形成現象とアポトーシスの関連性について2008

    • Author(s)
      八重柏隆, 藤木淳, 他3名
    • Journal Title

      日本歯科保存学会雑誌 51

      Pages: 99-104

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 円錐型チップを装着したEr : YAGレーザーの根管内スミヤー層除去効果2008

    • Author(s)
      古嶺嘉人, 松本妃可, 他5名
    • Journal Title

      日本歯科保存学会雑誌 51

      Pages: 156-162

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] クロルヘキシジン添加グラスアイオノマーセメント系シーラーの抗菌作用に関する研究2008

    • Author(s)
      西垣奏一郎, 古嶺嘉人, 他3名
    • Journal Title

      日本歯内療法学会雑誌 29

      Pages: 20-25

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 円錐型チップを用いたEr : YAGレーザーの根管内殺菌効果2008

    • Author(s)
      松本妃可, 古嶺嘉人, 他3名
    • Journal Title

      日本歯内療法学会雑誌 29

      Pages: 119-124

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 根管内破折ファイルの除去に内視鏡とEr : YAGレーザーを併用した2症例2008

    • Author(s)
      坂田篤信, 松本妃可, 他8名
    • Journal Title

      日本歯内療法学会雑誌 29

      Pages: 155-160

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gene profiles during root canal treatment in experimental rat periapical lesions2007

    • Author(s)
      Martinez ZR, Takashiba S., 他9名
    • Journal Title

      Journal of Endodontics 33巻

      Pages: 936-943

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Formation of dentin-like particles in dentin defects above exposed pulp by controlled release of fibroblast growth factor 2 from gelatin hydrogels2007

    • Author(s)
      Kikuchi N, Kitamura C, 他6名
    • Journal Title

      Journal of Endodontics 33巻

      Pages: 1198-1202

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of lipopolysaccharide on newly established rat dental pulp derived cell line with odontoblastic properties2007

    • Author(s)
      Nomiyama K, Kitamura C, 他5名
    • Journal Title

      Journal of Endodontics 33巻

      Pages: 1187-1191

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Kinetics of RANKL, RANK and OPG expressions in experimentally-induced rat periapical lesions、Oral Surgery, Oral Medicine, Oral Pathology2007

    • Author(s)
      Kawashima N., 他6名
    • Journal Title

      Oral Radiology, and Endodontology 103巻

      Pages: 707-711

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Kinetic study of immunohistochemical colocalization of antigen presenting cells and nerve fibers in rat periapical lesions2007

    • Author(s)
      Yang G, Kawashima N, 他4名
    • Journal Title

      Journal of Endodontics 33巻

      Pages: 132-136

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 炭酸ガスレーザー照射によるマウス象牙芽細胞様細胞の石灰化誘導に関する研究2007

    • Author(s)
      安田善之ら
    • Journal Title

      日本レーザー歯学会誌 18巻

      Pages: 123-129

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] In vitro comparison of the biocompatibility of mineral trioxide aggregate,4META/MMA-TBB resin,and intermediate restive material as root-end-filling materials2007

    • Author(s)
      Yoshimine Y., et. al.
    • Journal Title

      Journal of Endodontics 33

      Pages: 1066-1069

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gene profiles during root canal treatment in experimental rat periapical lesions2007

    • Author(s)
      Arias-Martinez Z.R., et. al.
    • Journal Title

      Journal of Endodontics 33

      Pages: 936-943

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of lipopolysaccharide on newly established rat dental pulp derived cell line with odontoblastic properties2007

    • Author(s)
      Noriyama K., et. al.
    • Journal Title

      Journal of Endodontics 33

      Pages: 1187-1191

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Formation of dentin-like particles in dentin defects above exposed pulp by controlled release of fibroblast growth factor 2 from gelatin hydrogels2007

    • Author(s)
      Kikuchi N., et. al.
    • Journal Title

      Journal of Endodontics 33

      Pages: 1198-1202

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Kinetics of RANKL,RANK and OPG expressions in experimentally-induced rat periapical lesions2007

    • Author(s)
      Kawashima N., et. al.
    • Journal Title

      Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 103

      Pages: 707-711

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Kinetic study of immunohistochemical colocalization of antigen presenting cells and nerve fibers in rat periapical lesions2007

    • Author(s)
      Yang G., et. al.
    • Journal Title

      Journal of Endodontics 33

      Pages: 132-136

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differentiation of an ameloblast-lineage cell line(ALC)is induced by Sonic hedgehog signaling2007

    • Author(s)
      Takahashi S., et. al.
    • Journal Title

      BBRC 353

      Pages: 405-411

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Localization of bromodeoxyurdine-incorporating,p63-and p75(NGFR)-expressing cells in the human aingival epithelium2007

    • Author(s)
      Hatakeyama S, et. al.
    • Journal Title

      Journal of Oral Science 49

      Pages: 287-291

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 炭酸ガスレーザー照射によるマウス象牙芽細胞様細胞の石灰化誘導に関する研究2007

    • Author(s)
      安田 善之, 他
    • Journal Title

      日本レーザー歯学会誌 18

      Pages: 123-129

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Er:YAGレーザーの根管内照射による影響-象牙質感染モデルにおける殺菌効果について-2007

    • Author(s)
      松本 妃可, 他
    • Journal Title

      日本歯科保存学雑誌 50

      Pages: 1066-1069

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of sequential exposure to lipopolysaccharide and heat stress on dental pulp cells2006

    • Author(s)
      Kitamura C, 他7名
    • Journal Title

      Journal of Cellular Biochemistry 99巻

      Pages: 797-806

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Re-oxygenation improves hypoxia induced pulp cell arrest2006

    • Author(s)
      Ueno Y, Kitamura C, 他2名
    • Journal Title

      Journal of Dental Research 85巻

      Pages: 824-828

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Er : YAG レーザーの根管内照射による影響2006

    • Author(s)
      松本妃可, 吉嶺嘉人, 赤峰昭文
    • Journal Title

      日本歯科保存学雑誌 49・6

      Pages: 749-754

    • Related Report
      2006 Annual Research Report
  • [Presentation] a3b1 integrin-mediated MC3T3-E1 osteoblasts adherence induced by interleukin-1a2008

    • Author(s)
      Takashi Tomiyama, Shogo Takashiba, 他3名
    • Organizer
      56^<th> Annual Meeting, Japanese Association for Dental Research
    • Place of Presentation
      名古屋市
    • Year and Date
      2008-11-30
    • Related Report
      2008 Final Research Report
  • [Presentation] a3b1 integrin-mediated MC3T3-E1 osteoblasts adherence induced by interleukin-1a2008

    • Author(s)
      Takashi Tomiyama, Koji Naruishi, 他3名
    • Organizer
      56^<th> Annual Meeting, 2008, Japanese Association for Dental Research
    • Place of Presentation
      名古屋市
    • Year and Date
      2008-11-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] Er : YAGレーザーのエンドへの応用-根管内殺菌効果に関する研究-2008

    • Author(s)
      松本妃可,吉嶺嘉人, 他4名
    • Organizer
      21回日本歯科医学会総会
    • Place of Presentation
      横浜市
    • Year and Date
      2008-11-15
    • Related Report
      2008 Final Research Report
  • [Presentation] Er : YAGレーザーのエンドへの応用-根管内殺菌効果に関する研究-2008

    • Author(s)
      藤原英明, 八重柏隆, 國松和司
    • Organizer
      第21回日本歯科医学会総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-11-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] 抗菌ペプチドLL37はヒト歯髄細胞のmigrationを促進する2008

    • Author(s)
      加治屋幹人,柴秀樹, 他6名
    • Organizer
      129回日本歯科保存学会秋季学術大会
    • Place of Presentation
      富山市
    • Year and Date
      2008-11-06
    • Related Report
      2008 Final Research Report
  • [Presentation] IL-1aおよびIL-1bによるマウス骨芽細胞様細胞MC3T3-E1の動態におけるMAPK系の関与2008

    • Author(s)
      冨山高史,高柴正悟, 他5名
    • Organizer
      129回日本歯科保存学会秋季学術大会
    • Place of Presentation
      富山市
    • Year and Date
      2008-11-06
    • Related Report
      2008 Final Research Report
  • [Presentation] IL-1aおよびIL-1bによるマウス骨芽細胞様細胞MC3T3-E1の動態におけるMAPK系の関与2008

    • Author(s)
      冨山高史, 成石浩司, 他5名
    • Organizer
      第129回日本歯科保存学会
    • Place of Presentation
      富山市
    • Year and Date
      2008-11-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] 抗菌ペプチドLL37はヒト歯髄細胞のmigrationを促進する2008

    • Author(s)
      加治屋幹人, 柴 秀樹, 他6名
    • Organizer
      第129回日本歯科保存学会
    • Place of Presentation
      富山市
    • Year and Date
      2008-11-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] Interleukin-6 decreases FGF-2 expression of human periodontal ligament cells2008

    • Author(s)
      藤原英明, 八重柏隆, 國松和司
    • Organizer
      86th IADR General session
    • Place of Presentation
      トロント(カナダ)
    • Year and Date
      2008-07-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] Efficient Removal of the Smear Layer Using Er : YAG laser s2008

    • Author(s)
      Yoshimine Y. Matsumoto H, Nishigaki S, Goto C, Akamine A.
    • Organizer
      IADR
    • Place of Presentation
      トロント(カナダ)
    • Year and Date
      2008-07-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] ラット根管治療モデルを用いた根尖周囲組織の遺伝子マイクロアレイ解析に基づいた根尖病巣治癒病態の考察2008

    • Author(s)
      冨山高史,高柴正悟, 他5名
    • Organizer
      128回日本歯科保存学会春季学術大会
    • Place of Presentation
      新潟市
    • Year and Date
      2008-06-06
    • Related Report
      2008 Final Research Report
  • [Presentation] ラット根管治療モデルを用いた根尖周囲組織の遺伝子マイクロアレイ解析に基づいた根尖病巣治癒病態の考察2008

    • Author(s)
      冨山高史, 成石浩司, 他5名
    • Organizer
      第128回日本歯科保存学会
    • Place of Presentation
      新潟市
    • Year and Date
      2008-06-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] 根管内視鏡観察下でのEr : YAGレーザーを用いた破折ファイルの除去2008

    • Author(s)
      松本妃可, 吉嶺嘉人, 他8名
    • Organizer
      第29回日本歯内療法学会
    • Place of Presentation
      東京歯科大学千葉校舎
    • Year and Date
      2008-05-24
    • Related Report
      2008 Annual Research Report
  • [Presentation] Notch Signaling in the Dental Pulp2008

    • Author(s)
      N. Kawashima, 他
    • Organizer
      86^<th> General Session & Exhibition of the International Association for Dental Research
    • Place of Presentation
      Toronto
    • Related Report
      2008 Final Research Report
  • [Presentation] Interleukin-6 decreases FGF-2 expression of human periodontal ligament cells2008

    • Author(s)
      Fujiwara H, Kunimatsu K, 他5名
    • Organizer
      86^<th> General Session & Exhibition of the International Association for Dental Research
    • Place of Presentation
      Toronto
    • Related Report
      2008 Final Research Report
  • [Presentation] Efficient Removal of the Smear Layer Using Er : YAG laser2008

    • Author(s)
      Yoshimine Y, 他4名
    • Organizer
      86^<th> General Session & Exhibition of the International Association for Dental Research
    • Place of Presentation
      Toronto
    • Related Report
      2008 Final Research Report
  • [Presentation] Keratocystic Odontogenic Tumor : Case Report2008

    • Author(s)
      Kawashima N, Kabasawa Y, Suda H
    • Organizer
      KAE Spring Scientific Meeting 37th
    • Place of Presentation
      Chosun Univ, Korea
    • Related Report
      2008 Annual Research Report
  • [Presentation] Notch Signaling in the Dental. Pulp2008

    • Author(s)
      Kawashima N., Takahashi S., 他10名
    • Organizer
      IADR General Session & Exhibition
    • Place of Presentation
      トロント(カナダ)
    • Related Report
      2008 Annual Research Report
  • [Presentation] Processing of Matrix Extracellular Phosphoglycoprotein in Dental Pulp Cells2008

    • Author(s)
      Wang H., Kawashima N., 他5名
    • Organizer
      IADR General Session & Exhibition
    • Place of Presentation
      トロント(カナダ)
    • Related Report
      2008 Annual Research Report
  • [Presentation] Shh Signaling is Related to BMP Signaling in Ameloblast Differentiation2008

    • Author(s)
      Takahashi S., Kawashima N., 他5名
    • Organizer
      IADR General Session & Exhibition
    • Place of Presentation
      トロント(カナダ)
    • Related Report
      2008 Annual Research Report
  • [Presentation] Role of Mef2c signaling in osteoblast differentiation2008

    • Author(s)
      Kawashima N., Takahashi S., 他10名
    • Organizer
      2008 Autumn Scientific Meeting (130th)of Korean Academy of Conservative Dentistry
    • Place of Presentation
      COEX Seoul Korea
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒアルロン酸スポンジに対する歯髄組織の炎症応答.2008

    • Author(s)
      犬山喜夫
    • Organizer
      第129回日本歯科保存学会
    • Place of Presentation
      富山
    • Related Report
      2008 Annual Research Report
  • [Presentation] 象牙芽細胞様細胞の有する象牙質形成能への熱刺激の影響.2008

    • Author(s)
      諸冨孝彦
    • Organizer
      第129回日本歯科保存学会
    • Place of Presentation
      富山
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒアルロン酸によるPC12細胞の神経突起伸長抑制効果におけるRHAMMレセプターの関与.2008

    • Author(s)
      鷲尾絢子
    • Organizer
      第129回日本歯科保存学会
    • Place of Presentation
      富山
    • Related Report
      2008 Annual Research Report
  • [Presentation] FGF-2濃度の違いが象牙質欠損部における硬組織誘導に与える影響.2008

    • Author(s)
      石松宏隆
    • Organizer
      第129回日本歯科保存学会
    • Place of Presentation
      富山
    • Related Report
      2008 Annual Research Report
  • [Presentation] BMPによる骨芽細胞分化における半導体レーザー照射の効果.2008

    • Author(s)
      平田志津
    • Organizer
      第129回日本歯科保存学会
    • Place of Presentation
      富山
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒアルロン酸によるPC12細胞のNGF誘導性神経突起伸長抑制効果発現メカニズムの解析.2008

    • Author(s)
      鷲尾絢子
    • Organizer
      第50回日本歯科基礎医学会学術大会・総会
    • Place of Presentation
      東京
    • Related Report
      2008 Annual Research Report
  • [Presentation] LPSの象牙芽細胞に対する活性はオゾン水により失活する.2008

    • Author(s)
      野口扶美子
    • Organizer
      第50回日本歯科基礎医学会学術大会・総会
    • Place of Presentation
      東京
    • Related Report
      2008 Annual Research Report
  • [Presentation] アロマセラピーが歯科診療環境に与える影響.2008

    • Author(s)
      吉田真理
    • Organizer
      第24回日本歯科人間工学会
    • Place of Presentation
      北九州
    • Related Report
      2008 Annual Research Report
  • [Presentation] 象牙芽細胞様細胞株(KN-3)ヘヒートストレスが与える影響.2008

    • Author(s)
      諸冨孝彦
    • Organizer
      第128回日本歯科保存学会
    • Place of Presentation
      新潟
    • Related Report
      2008 Annual Research Report
  • [Presentation] オゾン水による象牙芽細胞様細胞へのリポ多糖の効果の抑制.2008

    • Author(s)
      野口扶美子
    • Organizer
      第128回日本歯科保存学会
    • Place of Presentation
      新潟
    • Related Report
      2008 Annual Research Report
  • [Presentation] ゼラチン粒子から徐放されるFGF-2濃度が象牙質/歯髄複合体再生に与える影響.2008

    • Author(s)
      石松宏隆
    • Organizer
      第128回日本歯科保存学会
    • Place of Presentation
      新潟
    • Related Report
      2008 Annual Research Report
  • [Presentation] 象牙質/歯髄複合体再生にスキャホールドとして用いたヒアルロン酸の効果.2008

    • Author(s)
      犬山喜夫
    • Organizer
      第128回日本歯科保存学会
    • Place of Presentation
      新潟
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒアルロン酸はPC12細胞の神経突起誘導を抑制する.2008

    • Author(s)
      鷲尾絢子
    • Organizer
      第128回日本歯科保存学会
    • Place of Presentation
      新潟
    • Related Report
      2008 Annual Research Report
  • [Presentation] 臨床をシミュレートした環境下で行なった根管形成に与える臨床経験の影響.2008

    • Author(s)
      永吉雅人
    • Organizer
      第29回日本歯内療法学会
    • Place of Presentation
      千葉
    • Related Report
      2008 Annual Research Report
  • [Presentation] Er:YAGレーザーとRチップによる根管内スミヤー層除去効果2007

    • Author(s)
      吉嶺 嘉人, 他
    • Organizer
      第19回日本レーザー歯学会
    • Place of Presentation
      鶴見
    • Year and Date
      2007-11-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] 石灰化能を有するラット歯髄細胞におよぼすリポ多糖の影響2007

    • Author(s)
      野口 扶美子, 他
    • Organizer
      第127回日本歯科保存学会
    • Place of Presentation
      岡山
    • Year and Date
      2007-11-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] Pulp Apoptosis and Regeneration Induced by External Factors.In: Resin restoratives and dentin regeneration-Partnership or hostility?2007

    • Author(s)
      Kitamura C.
    • Organizer
      第55回国際歯科研究学会日本部会(JADR)総会・学術大会シンポジウム
    • Place of Presentation
      鶴見
    • Year and Date
      2007-11-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] IL-6のヒト歯髄細胞の増殖因子に与える影響について2007

    • Author(s)
      藤原 英明, 他
    • Organizer
      第127回日本歯科保存学会
    • Place of Presentation
      岡山
    • Year and Date
      2007-11-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] IL-6のヒト歯髄細胞の増殖因子に与える影響について2007

    • Author(s)
      藤原英明、八重柏隆、國松和司
    • Organizer
      127回日本歯科保存学会秋季学術大会
    • Place of Presentation
      岡山市
    • Year and Date
      2007-11-08
    • Related Report
      2008 Final Research Report
  • [Presentation] Bactericidal effects of Er:YAG laser irradiation within root canal dentinin vitro2007

    • Author(s)
      Matsumoto H., et. al.
    • Organizer
      7^<th> World Endodontic Congress of IFEA
    • Place of Presentation
      Vancouver
    • Year and Date
      2007-08-23
    • Related Report
      2007 Annual Research Report
  • [Presentation] Response of MC3T3-E1 osteoblast-like cells to mineral trioxide aggregate2007

    • Author(s)
      Ono M., et. al.
    • Organizer
      7^<th> World Endodontic Congress of IFEA
    • Place of Presentation
      Vancouver
    • Year and Date
      2007-08-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] Antibacterial property of an experimental glass-ionomer sealer combined with chlorhexidine2007

    • Author(s)
      Nishigaki S., et. al.
    • Organizer
      7^<th> World Endodontic Congress of IFEA
    • Place of Presentation
      Vancouver
    • Year and Date
      2007-08-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] ヒト抜去歯を用いた根管内殺菌作用に関する研究2007

    • Author(s)
      松本 妃可, 他
    • Organizer
      第10回Er:YAGレーザー臨床研究会記念大会
    • Place of Presentation
      京都
    • Year and Date
      2007-07-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] ラット根管治療モデルを用いた根尖性歯周炎の治癒過程における網羅的な遺伝子解析2007

    • Author(s)
      Arias Zulema,高柴正悟, 他6名
    • Organizer
      126回日本歯科保存学会春季学術大会
    • Place of Presentation
      大宮市
    • Year and Date
      2007-06-08
    • Related Report
      2008 Final Research Report
  • [Presentation] 各種サイトカインが石灰化能を有する歯髄細胞(KN-3)に与える影響2007

    • Author(s)
      永吉 雅人, 他
    • Organizer
      第126回日本歯科保存学会
    • Place of Presentation
      埼玉
    • Year and Date
      2007-06-07
    • Related Report
      2007 Annual Research Report
  • [Presentation] Er:YAGレーザーの根管内殺菌効果に関するin vitroでの研究2007

    • Author(s)
      松本 妃可, 他
    • Organizer
      第126回日本歯科保存学会
    • Place of Presentation
      大宮
    • Year and Date
      2007-06-07
    • Related Report
      2007 Annual Research Report
  • [Presentation] Bactericidal effects of Er;YAG laser irradiation within root canal dentin in vitro2007

    • Author(s)
      Matsumoto H., et. al.
    • Organizer
      第28回日本歯内療法学会
    • Place of Presentation
      広島
    • Year and Date
      2007-05-26
    • Related Report
      2007 Annual Research Report
  • [Presentation] クロルヘキシジン添加グラスアイオノマー系シーラーの抗菌性2007

    • Author(s)
      西垣 奏一郎, 他
    • Organizer
      第28回日本歯内療法学会
    • Place of Presentation
      広島
    • Year and Date
      2007-05-26
    • Related Report
      2007 Annual Research Report
  • [Presentation] グリコサミノグリカンを応用した歯髄及び歯周組織の再生医療に関する研究2007

    • Author(s)
      寺下 正道, 他
    • Organizer
      第67回九州歯科学会
    • Place of Presentation
      北九州
    • Year and Date
      2007-05-19
    • Related Report
      2007 Annual Research Report
  • [Presentation] DNA Microarray Analysis on Genes Expressed in Periapical Lesion2007

    • Author(s)
      A. Zulema, S. Takashiba, 他8名
    • Organizer
      85^<th> General Session & Exhibition of the International Association for Dental Research
    • Place of Presentation
      New Orleans
    • Year and Date
      2007-03-24
    • Related Report
      2008 Final Research Report
  • [Presentation] 炭酸ガスレーザー照射による象牙芽細胞の石灰化誘導2007

    • Author(s)
      安田 善之, 他
    • Organizer
      第87回北海道医学大会レーザー医学分科会
    • Place of Presentation
      札幌
    • Related Report
      2007 Annual Research Report
  • [Book] 保存修復専門用語集2009

    • Author(s)
      寺下正道
    • Total Pages
      160
    • Publisher
      医歯薬出版株式会社
    • Related Report
      2008 Annual Research Report
  • [Book] 歯内治療学第3版2007

    • Author(s)
      吉嶺 嘉人、北村 知昭, 他
    • Total Pages
      315
    • Publisher
      医歯薬出版
    • Related Report
      2007 Annual Research Report
  • [Book] 保存修復学第5版2007

    • Author(s)
      北村 知昭, 他
    • Total Pages
      412
    • Publisher
      医歯薬出版
    • Related Report
      2007 Annual Research Report
  • [Book] 実践歯内療法学2007

    • Author(s)
      吉嶺 嘉人, 他翻訳
    • Total Pages
      375
    • Publisher
      クインテッセンス出版
    • Related Report
      2007 Annual Research Report

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Published: 2006-04-01   Modified: 2020-04-22  

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