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Studies on the transmission and pathobiology of New and Old World leishmaniases

Research Project

Project/Area Number 18256004
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Parasitology (including Sanitary zoology)
Research InstitutionKochi University

Principal Investigator

HASHIGUCHI Yoshihisa  Kochi University, 名誉教授 (10037385)

Co-Investigator(Kenkyū-buntansha) UEZATO Hiroshi  琉球大学, 医学部, 教授 (60160157)
KATAKURA Ken  北海道大学, 大学院・獣医医学研究科, 教授 (10130155)
MIMORI Tatsuyuki  熊本大学, 医学部, 教授 (00117384)
ITO Makoto  愛知医科大学, 医学部, 教授 (90137117)
KATO Hirotomo  山口大学, 農学部, 准教授 (00346579)
KORENAGA Massataka  高知大学, 医学部, 准教授 (00128274)
YMMAMOTO Yu-ichi  琉球大学, 医学部, 助教 (00363672)
MANUEL Calvopina  高知大学, 医学部, 助教 (20346711)
Project Period (FY) 2006 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥42,510,000 (Direct Cost: ¥32,700,000、Indirect Cost: ¥9,810,000)
Fiscal Year 2009: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
Fiscal Year 2008: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
Fiscal Year 2007: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Fiscal Year 2006: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
Keywords国際交流研究 / エクアドル:ペルー:アルゼンチン:パキスタン:バングラデシュ / リーシュマニア症 / 媒介サシチョウバエ / 伝播疫学 / 分子生物学 / 病態生理 / Leishmania原虫感染 / 国際研究者交流 / エクアドル:ペルー:パキスタン:バングラデシュ / サシチョウバエ / リーシュマニア原虫 / LAMP法 / エクアドル / ペルー / アルゼンチン / パキスタン / バングラデシュ / ウタ症 / バルトネラ症 / アマスチゴート抗原 / ONO-4007
Research Abstract

Leishmaniasis is one of the protozoan infectious diseases transmitted by blood-sucking insects, sandflies. The disease is widely distributed, affecting at least 12 million people in 88 countries of the world. In this study, three disease factors, patients, vector sandflies, and reservoir animals, were investigated by employing molecular biological, immunological and epidemiological methods. Main results obtained are as follows : (1) relation between Leishmania spp. and disease forms, (2) determination of vector species, (3) search for different mammals infected with Leishmania, (4) development of rapid diagnosis and treatment, (5) search for control measures at each endemic area.

Report

(6 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report   Self-evaluation Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (90 results)

All 2010 2009 2008 2007 2006 Other

All Journal Article (59 results) (of which Peer Reviewed: 48 results) Presentation (23 results) Book (8 results)

  • [Journal Article] Molecular epidemiology for vector research on leishmaniasis2010

    • Author(s)
      Hirotomo Kato, Eduardo A. Gomez, Abraham G. Caceres, Hiroshi Uezato, Tatsuyuki Mimori, Yoshihisa Hashiguchi
    • Journal Title

      International Journal of Environmental Research and Public Health 7

      Pages: 814-82

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A survey of cutaneous leishmaniasis at village Gaibi Dero, District Larkana, Sindh, Pakistan2010

    • Author(s)
      Farooq R. Soomro, Ghuram M. Pathan, Parvez Abbasi, Doulat Bajaj, Nuzhat S. Bhartti, Javed Hussain, Abdul M. Bhutto, Yoshihisa Hashiguchi
    • Journal Title

      Gomal Journal of Medical Science 7

      Pages: 137-139

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Natural infection of the sand fly Phlebotomus kazeruni by Trypanosom species in Pakistan2010

    • Author(s)
      Hirotomo Kato, Hiroshi Uezato, Hiroshi Sato, Abdul M. Bhutto, Farooq R. Soomro, Javed Hussain, Hiroyuki Iwata, Yoshihisa Hashiguchi
    • Journal Title

      Parasites and Vectors 9

      Pages: 10-16

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A repertoire of the dominant transcripts from the salivary glands of the blood-sucking bug, Triatoma dimidiata, a vector of Chagas Infection2010

    • Author(s)
      Hirotomo Kato, Ryan C. Jochim, Eduardo A. Gomez, Ryo Sakoda, Hiroyuki Iwata, Jesus G. Valenzuela, Yoshihisa Hashiguchi
    • Journal Title

      Genetics and Evolution 10

      Pages: 184-191

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A repertoire of the dominant transcripts from the salivary glands of the blood-sucking bug, Triatoma dimidiata, a vector of Chagas disease2010

    • Author(s)
      Hirotomo Kato, et al
    • Journal Title

      Infection, Genetics and Evolution 10

      Pages: 184-191

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Natural infection of the sand fly Phlebotomus kazeruni by Trypanosoma species in Pakistan2010

    • Author(s)
      Hirotomo Kato, et al
    • Journal Title

      Parasites and Vectors 3

      Pages: 10-16

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A survey of cutaneous leishmaniasis at village Gaibi Dero, District Larkana, Sindh, Pakistan2010

    • Author(s)
      Rhaman Soomro, et al
    • Journal Title

      Gomal Journal of Medical Science 7

      Pages: 137-139

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular epidemiology for vector research on leishmaniasis2010

    • Author(s)
      Hirotomo Kato, et al
    • Journal Title

      Int.J.of Environm.Res.and Public Health 7

      Pages: 814-824

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cutaneous leishman-iasis caused by Leishmania (L. ) major infection in Sindh province, Pakistan2009

    • Author(s)
      Abdul Manan Bhutto, Farooq R. Soomro, Javed hussain, Jun Matsumoto, Hiroshi Uezato, Yoshihisa Hashiguchi, Ken Katakura
    • Journal Title

      Acta Tropica 111

      Pages: 295-298

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sensitive, specific and rapid detection of Leishmania donovani DNA by loop-mediated isothermal amplifica-tion2009

    • Author(s)
      Hidekazu Takagi, Makoto Itoh, Mohammad Zahidul Islam, Abdur Razzaque, A.R.M. Saifuddin Ekram, Yoshihisa Hashiguchi, Eisei Noiri, Eisaku Kimura
    • Journal Title

      American Journal of Tropical Medicine and Hygiene 81

      Pages: 578-582

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Genetic diversity of ribosomal RNA internal transcribed spacer sequences in Lutzomyia species from areas endemic for New World cutaneous leishmaniasis2009

    • Author(s)
      Kei Kuwahara, Hirotomo Kato, Eduardo A. Gomez, Hiroshi Uezato, Tatsuyuki Mimori, Yuichi Yamamoto, Manuel Calvopina, Abraham G. Caceres, Hiroyuki Iwata, Yoshihisa Hashiguchi
    • Journal Title

      Acta Tropica 112

      Pages: 131-136

    • Related Report
      2009 Final Research Report
  • [Journal Article] Phylogenic analysis of the genus Leishmania by cytochrome b gene sequencing2009

    • Author(s)
      Yutaka Asato, Minoru Oshiro, Chomar Kaung Myint, Yu-ichi Yamamoto, Hirotomo Kato, Jorge Diego Marco, Tatsuyuki Mimori, Eduardo A.L. Gomez, Yoshihisa Hashiguchi, Hiroshi Uezato
    • Journal Title

      Experimental Parasitology 121

      Pages: 352-361

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Population structure and geographical subdivision of the Leishmania major vector Phelebotomus papatasi as revealed by microsatellite variation2009

    • Author(s)
      Omar Hamarsheh, W. Presber, M.R. Yaghoobi-Ershadi, A. Amro, A. AL-Jawabreh, S. Sawalha, A. AL-Lahem, M.L. Das, S. Guernaoui, N. Seridi, R.C. Dhiman, Yoshihisa Hashiguchi, J. Ghrab, M. Hassan, G. Schonian
    • Journal Title

      Medical and Veterinary Entomology 23

      Pages: 69-77

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cutaneous leishmaniasis caused by Leishmania(L.)major infection in Sindh province, Pakistan2009

    • Author(s)
      Abdul Manan Bhutto, et al.
    • Journal Title

      Acta Tropica 111

      Pages: 295-298

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic diversity of ribosomal RNA internal transcribed spacer sequences in Lutzomyia species from areas endemic for New World cutaneous leishmaniasis2009

    • Author(s)
      Kei Kuwahara, et al.
    • Journal Title

      Acta Tropica 112

      Pages: 131-136

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sensitive, specific and rapid detection of Leishmania donovani DNA by loop-mediated isothermal amplification2009

    • Author(s)
      Hidekazu Takagi, et al
    • Journal Title

      American Journal of.Tropical Medicine and Hygiene 81

      Pages: 578-582

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phylogenic analysis of the genus Leishmania by cytochrome bgene sequencing2009

    • Author(s)
      Yutaka Asato, et al.
    • Journal Title

      Experimental Parasitology 121

      Pages: 352-361

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Population structure and geographical subdivision of the Leishmania major vector Phelebotomus papatasi as revealed by microsatellite variation2009

    • Author(s)
      0. Hamarsheh, et al.
    • Journal Title

      Medical and Veterinary Entomology 23

      Pages: 69-77

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Polymorphisms of cytochrome b gene in Leishmania parasites and their relation to types of cutaneous leishmaniasis lesions in Pakistan2008

    • Author(s)
      Chomar Kaung Myint, Yutaka Asato, Yu-ichi Yamato, Hirotomo Kato, Abdul M. Bhutto, Farooq R. Soomro, Muhamad Z. Momen, Jun Mataumoto, Jorge D. Marco, Minoru Oshiro, Ken Katakura, Yoshihisa Hashiguchi, Hiroshi Uezato
    • Journal Title

      Journal of Dermatology 35

      Pages: 76-85

    • NAID

      10024296570

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Deformity and disability index in patients of leprosy in Larkana region2008

    • Author(s)
      Farooq Rahman Soomro, Ghulam Murtaza Pathan, Parvez Abbasi, Nuzhat Seema Bhatti, Javeed Hussain, Yoshihisa Hashiguchi
    • Journal Title

      Journal of Pakistan Association of Dermatologists 18

      Pages: 29-32

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Natural infection of Lutzomyia tortura with Leishmania(Viannia) naiffi in an Amazonian area of Ecuador2008

    • Author(s)
      Hirotomo Kato, Eduardo A. Gomez, Yu-ichi Yamamoto, Manuel Calvopina, Angel G. Guevara, Jorge D. Marco, Paola A. Barroso, Hiroyuki Iwata, Yoshihisa Hashiguchi
    • Journal Title

      American Journal of Tropical Medicine and Hygiene 79

      Pages: 438-440

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Enzyme-linked immunosorbent assay to detecd urinary antibody against recombinant rKRP42 antigen made from Leishmania donovani for the diagnosis of visceral leishmaniasis2008

    • Author(s)
      Mohammad Zahidul Islam, Makoto Itoh, Hidekazu Takagi, Anwar UI Islam, A. R. M. Saifuddin Ekram, Ajijur Rahman, Atsuhide Takesue, Yoshihida Hashiguchi, Eisaku Kimura
    • Journal Title

      American Journal of Tropical Medicine and Hygiene 79

      Pages: 599-604

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Molecular mass screening to incriminate sand fly vectors of Andean-type cutaneous Leishmaniasis in Ecuador and Peru2008

    • Author(s)
      Hirotomo Kato, Abraham G. Caceres, Eduardo A. Gomez, Tatsuyuki Mimori, Hiroshi Uezato, Jorge D. Marco, Paola A. Barroso, Hiroyuki Iwata, Yoshihisa Hashiguchi
    • Journal Title

      American Journal of Tropical Medicine and Hygiene 79

      Pages: 719-72

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Enzyme-linked immunosorbent assay to detect urinary antibody against recombinant rKRP42 antigen made from Leishmania donovani for the diagnosis of visceral leishmaniasis2008

    • Author(s)
      Islam, M.Z., Itoh, M., Takagi, H., Islam, A.U., Ekram, A.R.M.S., Rahman, A., Takesue, A., Hashiguchi, Y.& Kimura, E.
    • Journal Title

      American Journal of Tropical Medicine and Hygiene 79

      Pages: 599-604

    • NAID

      120001671573

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Polymorphisms of cytochrome b gene in Leishmania parasites and their relation to types of cutaneous leishmaniasis lesions in Pakistan2008

    • Author(s)
      Chomar Kaung MYINT, et al.
    • Journal Title

      Journal of Dermatology 35

      Pages: 76-85

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Deformity and disability index in patients of leprosy in Larkana region2008

    • Author(s)
      Farooq Rahman Soomro, et al.
    • Journal Title

      Journal of Pakistan Association of Dermatologists 18

      Pages: 29-32

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular typing of sand fly species(Diptera, Psychodidae, Phlebotominae)from areas endemic for leishmaniasis in Ecuador by PCR-RFLP of 18S ribosomal RNA gene2008

    • Author(s)
      Yoshimi Terayama, et al.
    • Journal Title

      J. Vet. Med. Sci. 70

      Pages: 907-913

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enzyme-linked immunosorbent assay to detecd urinary antibody against recombinant rKRP42 antigen made from Leishmania donovani for the diagnosis of visceral Leishmaniasis2008

    • Author(s)
      Mohammad Zahidul Islam, et al.
    • Journal Title

      Am. J. Trop. Med. Hyg. 79

      Pages: 599-604

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Natural infection of Lutzomyia tortura with Leishmania (Viannia) naiffi in an Amazonian area of Ecuador.2008

    • Author(s)
      Hirotomo Kato, et al.
    • Journal Title

      Am. J. Trop. Med. Hyg. 79

      Pages: 438-440

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular mass screening to incriminate sand fly vectors of Andean-type cutaneous leishmaniasis in Ecuador and Peru.2008

    • Author(s)
      Hirotomo Kato, et al.
    • Journal Title

      Am. J. Trop. Med. Hyg. 79

      Pages: 719-723

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The identification of sandfly species, from an area of Argentina with endemic leishmaniasis, by the PCR-based analysis of the gene coding for 18S ribosomal RNA2007

    • Author(s)
      Paola Andrea Barroso, Jorge D. Marco, Hirotomo Kato, R. Tarama, P. Rueda, S.P. Cajal, Miguel A. Basombrio, Masataka Korenaga, N.J. Taranto, Yoshihisa Hashiguchi
    • Journal Title

      Annals of Tropical Medicine and Parasitology 101

      Pages: 247-253

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Production of recombinant kinesin-related protein of Leishmania donovani and its application in the serodiagnosis of visceral leishmaniasis2007

    • Author(s)
      Hidekazu Takagi, Mohammad Zahidul Islam, Makoto Itoh, Anwar UL Islam, A.R.M. Saifuddin Ekaram, Sultanamonira Hussain, Yoshihisa Hashiguchi, Eisaku Kimura
    • Journal Title

      American Journal of Tropical Medicine and Hygiene 76

      Pages: 902-905

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ocular disabilities in leprosy, Larkana District, Sindh, Pakistan2007

    • Author(s)
      Farooq Rahman Soomro, Ghulam Murtaza Pthan, Parvez Abbasi, Nuzhat Seema Bhatti, Javeed Hussain, Yoshihisa Hashiguchi
    • Journal Title

      Journal of Pakistan Association of Dermatologists 17

      Pages: 11-13

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A trial of immuno-therapy against Leishmania amazonensis infection in vitro and in vivo with Z-100, a polysaccharide obtained from Mycobacterium tuberculosis, alone or combined with meglumine antimoniate2007

    • Author(s)
      Paola Andrea Barroso, Jorge Diego Marco, Manuel Calvopina, Hirotomo Kato, Masataka Korenaga, Yoshihisa Hashiguchi
    • Journal Title

      Journal of Antimicrobial Chemotherapy 59

      Pages: 1123-1129

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Establishment of a mass screening method of sand fly vectors for Leishmania infection by molecular biological methods2007

    • Author(s)
      Hirotomo Kato, Hiroshi Uezato, Eduardo A. Gomez, Yoshimi Terayama, Manuel Calvopina, Hiroyuki Iwata, Yoshihisa Hashiguchi
    • Journal Title

      American Journal of Tropical Medicine and Hygiene 77

      Pages: 324-329

    • NAID

      120001671575

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Establishment of mass screening method of sandfly vector for Leishmania infection by molecular biological methods2007

    • Author(s)
      Kato, H., Uezato, H., Gomez, E.A.L., Terama, Y., Calvopina, M., Iwata, H. & Hashiguchi, Y.
    • Journal Title

      American Journal of Tropical Medicine and Hygiene 77

      Pages: 324-329

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] The identification of sandfly species,from an area of Argentina with endemic leishmaniasis,by the PCR-based analysis of the gene coding for 18S ribosomal RNA2007

    • Author(s)
      P.A.BARROSO, et. al.
    • Journal Title

      Annals of Tropical Medicine and Parasitology 101

      Pages: 247-253

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Production of recombinant kinesin-related protein of Leishmania donovani and its application in the serodiagnosis of visceral Leishmaniasis2007

    • Author(s)
      Hidekazu Takagi, et. al.
    • Journal Title

      Am.J.Trop.Med.Hyg 76

      Pages: 902-905

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ocular disabilities in leprosy,Larkana District,Sindh,Pakistan2007

    • Author(s)
      Farooq Rahman Soomro, et. al.
    • Journal Title

      Journal of Pakistan Association of Dermatologists 17

      Pages: 11-13

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A trial of immunotherapy against Leishmania amazonensis infection in vitro and in vivo with Z-100,a polysaccharide obtained from Mycobacter ium tuberculosis,alone or combined with meglumine antimoniate2007

    • Author(s)
      P.A.BARROSO, et. al.
    • Journal Title

      Journal of Antimicrobial Chemotherapy 59

      Pages: 1123-1129

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Establishment of a Mass Screening Method of Sand Fly Vectors for Leishmania Infection by Molecular Biological Method2007

    • Author(s)
      Hirotomo Kato, et. al.
    • Journal Title

      Am.J.Trop.Med.Hyg 77

      Pages: 324-329

    • NAID

      120001671575

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The identification of sandfly species, from an area of Argentina with endemic leishmaniasis, by the PCR-based analysis of the gene coding for 18S ribosomal RNA.2007

    • Author(s)
      Paola Andrea Barroso
    • Journal Title

      Annals of Tropical Medicine and Parasitology 101・3

      Pages: 247-253

    • Related Report
      2006 Annual Research Report
  • [Journal Article] A trial of immunotherapy against Leishmania amazonensis infection in vitro and in vivo with Z-100, a polysaccharide obtained from Mycobacterium tuberculosis, alone or combined with meglumine antimoniate2007

    • Author(s)
      Paola Andrea Barroso
    • Journal Title

      Journal of Antimicrobial Chemotherapy (印刷中)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Production of recombinant kinesin-related proteins of Leishmania donovani and its application in the Serodiagnosis of visceral leishmaniasis2007

    • Author(s)
      Hidekazu Takagi
    • Journal Title

      American J. Tropical Medicine and Hygiene 76・5(印刷中)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Mass screening of sand fly vectors from endemic areas of leishmaniasis in Ecuador by molecular biological method2007

    • Author(s)
      Hirotomo Kato
    • Journal Title

      American J. Tropical Medicine and Hygiene 76・6(印刷中)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Molecular typing of sand fly species from areas endemic for leishmaniasis in Ecuador by PCR-RFLP of 18S ribosomal RNA gene2007

    • Author(s)
      Yoshimi Terayama
    • Journal Title

      Medical and Veterinary Entomology 21.2(印刷中)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Leishmaniasis recidiva cutis due to Leishmania (Viannia) panamensis in subtropical Ecuador: isoenzymatic characterization2006

    • Author(s)
      Manuel Calvopina, Hiroshi Uezato, Eduardo A. Gomez, Masataka Korenaga, Shigeo Nonaka, Yoshihisa Hashiguchi
    • Journal Title

      International Journal of Dermatology 45

      Pages: 116-120

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Are cytochrome βgene sequencing and polymorphism-specific polymerase chain reaction as reliable as multilocus enzyme electrophoresis for identifying Leishmania spp. from Argentina?2006

    • Author(s)
      Jorge D. Marco, Hiroshi Uezato, Tatsuyuki Mimori, Paola A. Barroso, Masataka Korenaga, Shigeo Nonaka, Miguel A. Basombrio, Nestor J. Taranto, Yoshihisa Hashiguchi
    • Journal Title

      American Journal of Tropical Medicine and Hygiene 75

      Pages: 256-260

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Multilocus enzyme electrophoresis and cytochrome b gene sequencing-based identification of Leishmania isolates from different foci of cutaneous leishmaniasis in Pakistan2006

    • Author(s)
      Marco, J.D., Bhutto, A.M., Soomro, F.R., Baloch, J.H., Barroso, P.A., Hirotomo Kato, Hiroshi Uezato, Ken Katakura, Masataka Korenaga, Sigeo Nonaka, Yoshihisa Hashiguchi
    • Journal Title

      American Journal of Tropical Medicine and Hygiene 75

      Pages: 261-266

    • NAID

      120001671578

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of vaccination with a combination of Leishmania amastigote antigens and the lipid A-analogue ONO-4007 for immunoprophylaxis and immunotherapy against Leishmania amazonensis infection in a murine model of New World cutaneous leishmaniasis2006

    • Author(s)
      Manuel Calvopina, Paola A. Barroso, Jorge D. Marco, Masataka Korenaga, Philip J. Cooper, Shigeo Nonaka, Yoshihisa Hashiguchi
    • Journal Title

      Vaccine 24

      Pages: 5645-5652

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Leishmania isoenzyme polymorphisms in Ecuador: Relationships with geographic distribution and clinical presentation2006

    • Author(s)
      Manuel Calvopina, Rodrigo X Armijos, Jorge D. Marco, Hiroshi Uezato, Hirotomo Kato, Eduardo A Gomez, Masataka Korenaga, Paola A Barroso, Tatsuyuki Mimori, Philip J Cooper, Shigeo Nonaka, Yoshihisa Hashiguchi
    • Journal Title

      BMC Infectious Diseases 6

      Pages: 1-9

    • NAID

      120001687067

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relapse of New World diffuse cutaneous leishmaniasis caused by Leishmania (Leishmania) mexicana after miltefosine treatment2006

    • Author(s)
      Manuel Calvopina, Eduardo A. Gomez, Herbert Sindermann, Philip J. Cooper, Yoshihisa Hashiguchi
    • Journal Title

      American Journal of Tropical Medicine and Hygiene 75

      Pages: 1074-1077

    • NAID

      120001671577

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of vaccination with a combination of Leishmania amastigote antigens and the lipid A-analogue ONO-4007 for immunoprophylaxis and immunotherapy against Leishmania amazonensis infection in a murine model for New World cutaneous leishmaniasis2006

    • Author(s)
      Calvopina, M., Barroso, P.A., Marco, J.D., Korenaga, M., Cooper, P.J., Nonaka, S. & Hashiguchi, Y.
    • Journal Title

      Vaccine 24

      Pages: 5645-5652

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Are cytochrome b gene sequencing and polymorphism-specific polymerase chain reaction as reliable as multilocus enzyme electrophoresis for identifying Leishmania spp. from Argentina?2006

    • Author(s)
      Jorge D. Marco
    • Journal Title

      American J. Tropical Medicine and Hygiene 75・2

      Pages: 256-260

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Multilocus enzyme electrophoresis and cytochrome b gene sequencing-based identification of Leishmania isolates from different foci of cutaneous leishmaniasis in Pakistan.2006

    • Author(s)
      Jorge D. Marco
    • Journal Title

      American J. Tropical Medicine and Hygiene 75・2

      Pages: 261-266

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Efficacy of vaccination with a combination of Leishmania amastigote antigens and the lipid A-analogue ONO-4007 for immunoprophylaxis and immunotherapy against Leishmania amazonensis infection in a murine model of New World cutaneous leishmaniasis.2006

    • Author(s)
      Manuel Calvopina
    • Journal Title

      VACCINE 24・27-28

      Pages: 5645-5652

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Leishmania isoenzyme polymorphisms in Ecuador : Relationships with geographic distribution and clinical presentation.2006

    • Author(s)
      Manuel Calvopina
    • Journal Title

      BMC Infectious Diseases 6:139

      Pages: 1-9

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Relapse of new world diffuse cutaneous leishmaniasis caused by Leishmania (Leishmania) mexicana after miltefosine treatment.2006

    • Author(s)
      Manuel Calvopina
    • Journal Title

      American J. Tropical Medicine and Hygiene 75・6

      Pages: 1074-1077

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Molecular typing of sand fly species(Diptera, Psychodidae, Phlebotominae) from areas endemic for leishmaniasis in Ecuador by PCR-RFLP of 18S ribosomal RNA gene

    • Author(s)
      Yoshimi Terayama, Hirotomo Kato, Eduardo A. Gomez, Hiroshi Uezato, Manuel Calvopina, Hiroyuki Iwata, Yoshihisa Hashiguchi
    • Journal Title

      Journal of Veterinary Medical Science 70

      Pages: 907-913

    • NAID

      110006946005

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Presentation] Establishment of a mass screening method of sand fly vectors for Leishmania infection by molecular biological methods(研究奨励賞受賞講演)2009

    • Author(s)
      加藤大智
    • Organizer
      第50回日本熱帯医学会大会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県那覇市)
    • Year and Date
      2009-10-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] シャーガス病媒介サシガメ Triatoma dimidiata の唾液腺遺伝子転写産物の網羅的解析2009

    • Author(s)
      加藤大智
    • Organizer
      第50日本熱帯医学会大会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県那覇市)
    • Year and Date
      2009-10-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] Triatoma(T.)dimidiate の唾液腺トランスクリプトーム解析2009

    • Author(s)
      加藤大智
    • Organizer
      第148回日本獣医学会
    • Place of Presentation
      鳥取県立図書館(鳥取県鳥取市)
    • Year and Date
      2009-09-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Lutozomyia 属サシチョウバエrRNA遺伝子ITS領域の遺伝子多様性2009

    • Author(s)
      桑原慶
    • Organizer
      第148回日本獣医学会
    • Place of Presentation
      鳥取県立図書館(鳥取県鳥取市)
    • Year and Date
      2009-09-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] サシガメの唾液腺トランスクリプトーム解析2009

    • Author(s)
      加藤大智
    • Organizer
      第61回日本衛生動物学会大会
    • Place of Presentation
      サンポートホール高松(香川県高松市)
    • Year and Date
      2009-04-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] サシチョウバエの遺伝子タイピング法の確立と応用2008

    • Author(s)
      加藤大智, 他
    • Organizer
      第63回日本衛生動物学会西日本支部大会
    • Place of Presentation
      兵庫神戸大学
    • Year and Date
      2008-11-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] FTAカードを用いたリーシュマニア症の遺伝子診断の検討2008

    • Author(s)
      三森龍之, 他
    • Organizer
      第61回日本寄生虫学会南日本支部大会。第58回日本衛生動物学会南日本支部大会合同大会
    • Place of Presentation
      沖縄 沖縄産業支援センター
    • Year and Date
      2008-11-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] エクアドル共和国アマゾン地域におけるリーシュマニア症の疫学調査2008

    • Author(s)
      加藤大智, 他
    • Organizer
      第49回日本熱帯医学会大会・第23回日本国際保健医療学会学術大会
    • Place of Presentation
      東京 国立国際医療センター
    • Year and Date
      2008-10-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] リーシュマニア原虫感染サシチョウバエのマススクリーニング法の開発と南米アンデスの疾患流行地での疫学調査への応用2008

    • Author(s)
      加藤大智, 他
    • Organizer
      第60回日本衛生動物学会大会
    • Place of Presentation
      栃木 自治医科大学
    • Year and Date
      2008-04-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] The IgG3 are sensitive markers for the follow-up of Pentaval-ent antimonialstreatment of American cutaneous leishmaniasis2008

    • Author(s)
      Marco Jorge D., et al.
    • Organizer
      第77回日本寄生虫学会大会
    • Place of Presentation
      長崎 長崎ブリックホール
    • Year and Date
      2008-04-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 南米ペルーアンデス地域のおけるリーシュマニア症とその原虫種について2008

    • Author(s)
      三森龍之, 他
    • Organizer
      第77回日本寄生虫学会大会
    • Place of Presentation
      長崎 長崎ブリックホール
    • Year and Date
      2008-04-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] Typing of sandflies by restriction fragment length polymorphism of 18S ribosomal RNA gene from an endemic area of leishmanisis in Argentina2008

    • Author(s)
      Barroso Paola A., et al.
    • Organizer
      第77回日本寄生虫学会大会
    • Place of Presentation
      長崎 長崎ブリックホール
    • Year and Date
      2008-04-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] リーシュマニア症の研究と対策を中心とした国際医学・医療協力活動(シンポジウム)2007

    • Author(s)
      橋口義久
    • Organizer
      日本熱帯医学会・日本国際保健医療学会合同大会総会
    • Place of Presentation
      大阪大学コンベンションセンター
    • Year and Date
      2007-10-08
    • Related Report
      2009 Final Research Report
  • [Presentation] リーシュマニア症の研究と対策を中心とした国際医学・医療協力活動2007

    • Author(s)
      橋口義久
    • Organizer
      日本国際保健医療学会総会
    • Place of Presentation
      大阪大学コンベンションセンター
    • Year and Date
      2007-10-08
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] リーシュマニア症の研究と対策を中心とした国際医学・医療協力活動2007

    • Author(s)
      橋口 義久
    • Organizer
      第22回日本国際保健医療学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-10-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] リーシュマニア原虫感染サシチョウバエの大量スクリーニング系の確立2007

    • Author(s)
      加藤 大智, 他
    • Organizer
      第143回獣医学会
    • Place of Presentation
      つくば市
    • Related Report
      2007 Annual Research Report
  • [Presentation] エクアドルにおけるサシチョウバエの遺伝子タイピング法の確立2007

    • Author(s)
      寺山 好美, 他
    • Organizer
      第143回獣医学会
    • Place of Presentation
      つくば市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Immunoglobulin isotypes and IgG subclasses as molecular markers of efficacy of Pentavalent antimonials treatment of American tegumentary leishmaniasis2007

    • Author(s)
      Marco JD, et. al.
    • Organizer
      第63回日本寄生虫学会西日本支部大会
    • Place of Presentation
      高知市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Sandfly species identification by DNA polymorphism of 18S ribosomal RNA gene from an endemic area of leishmaniasis in Argentina2007

    • Author(s)
      Barroso PA, et. al.
    • Organizer
      第63回日本寄生虫学会西日本支部大会
    • Place of Presentation
      高知市
    • Related Report
      2007 Annual Research Report
  • [Presentation] リーシュマニア原虫感染サシチョウバエのマススクリーニング法の開発と南米アンデスの疾患流行地での疫学調査への応用2007

    • Author(s)
      加藤 大智, 他
    • Organizer
      第48回日本熱帯医学会大会
    • Place of Presentation
      別府市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Prediction of clinical viscera1 leishmaniasis cases in its early stages by rKRP42 urine-based ELISA2007

    • Author(s)
      Islam Mohammad Zahidul, et. al.
    • Organizer
      第48回日本熱帯医学会大会
    • Place of Presentation
      別府市
    • Related Report
      2007 Annual Research Report
  • [Presentation] パキスタンにおける皮膚型リーシュマニア症のチトクロームb遺伝子多型と皮膚症状の関係2007

    • Author(s)
      MYINT CH0MAR K, et. al.
    • Organizer
      第48回日本熱帯医学会大会
    • Place of Presentation
      別府市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Investigation of Loop-Mediated Amplification(LAMP)method for identification of cutaneous leishmanisis in Latin America2007

    • Author(s)
      Matsumoto T., et. al.
    • Organizer
      Forum Che ju-13
    • Place of Presentation
      Che ju(Korea)
    • Related Report
      2007 Annual Research Report
  • [Book] 人獣共通感染症(改訂版)2010

    • Author(s)
      橋口義久(木村哲・喜田宏編)
    • Publisher
      医薬ジャーナル社(印刷中)
    • Related Report
      2009 Annual Research Report
  • [Book] 医学大辞典第2版(伊藤正男, 他編)2008

    • Author(s)
      橋口義久
    • Publisher
      医学書院
    • Related Report
      2009 Final Research Report
  • [Book] バイオセイフテイーの事典(バイオメデイカルサイエンス研究会編)2008

    • Author(s)
      橋口義久
    • Publisher
      医学評論社
    • Related Report
      2009 Final Research Report
  • [Book] バイオセーフティの事典2008

    • Author(s)
      橋口義久(バイオメディカルサイエンス研究会[編])
    • Publisher
      みみずく舎
    • Related Report
      2008 Annual Research Report
  • [Book] 医学大辞典 2版2008

    • Author(s)
      橋口義久(伊藤正男, 他 編)
    • Publisher
      医学書院
    • Related Report
      2008 Annual Research Report
  • [Book] Studies on New and Old World leishmaniases and their transmission, with particular reference to Ecuador, Peru, Argentina and Pakistan2007

    • Author(s)
      Hashiguchi, Y. (ed.)
    • Publisher
      Kyowa Printing
    • Related Report
      2009 Final Research Report
  • [Book] Studies on New and Old World leishmaniases and their transmission, with particular reference to Ecuador, Peru, Argentina and Pakistan2007

    • Author(s)
      Hashiguchi, Y.
    • Publisher
      Kyowa Printing
    • Related Report
      2008 Self-evaluation Report
  • [Book] リーシュマニア症-戦乱が拡げる黒熱病流行-。別冊医学のあゆみ2006

    • Author(s)
      橋口 義久
    • Total Pages
      5
    • Publisher
      医歯薬出版
    • Related Report
      2006 Annual Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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