| Project/Area Number |
18300140
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Laboratory animal science
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| Research Institution | Shiga University of Medical Science |
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Principal Investigator |
TORII Ryuzo Shiga University of Medical Science, 動物生命科学研究センター, 教授 (50106647)
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| Co-Investigator(Kenkyū-buntansha) |
OKAHARA Junko 滋賀医科大学, 動物生命科学研究センター, 助教 (20464175)
TSUCHIYA Hideaki 滋賀医科大学, 動物生命科学研究センター, 技術専門職員 (10378440)
TAKADA Tatsuyuki 立命館大学, 薬学部, 教授 (90206756)
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| Research Collaborator |
IWATANI Chizuru 滋賀医科大学, 動物生命科学研究センター, 教務補佐員
YAMASAKI Jyuri 滋賀医科大学, 動物生命科学研究センター, 教務補佐員
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| Project Period (FY) |
2006 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥18,430,000 (Direct Cost: ¥15,100,000、Indirect Cost: ¥3,330,000)
Fiscal Year 2009: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2008: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2007: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2006: ¥4,000,000 (Direct Cost: ¥4,000,000)
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| Keywords | カニクイザル / 体細胞核移植 / テーラーメードES細胞 / ライブセルイメージング / 電気融合 / 細胞質内注入 / 初期化 |
|---|
| Research Abstract |
For the tailor-made ES cell establishment method using the somatic cell nuclear transfer method in the cynomlgus monkey, in addition to problem of embryo loss, the efficiency for creating blastocyst-stage embryos was extremely poor, and we reached the determination that regrettably ES cell establishment was extremely difficult. On the other hand, it was relatively easy to establish cynomolgus monkey iPS cells, and it goes without saying that iPS cells are expected to be useful in clinical application research.
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