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Surface treatments of bone fixators consiting of titanium alloys to inhibit the formation of callus

Research Project

Project/Area Number 18300160
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionTokyo Medical and Dental University

Principal Investigator

HANAWA Takao  Tokyo Medical and Dental University, 生体材料工学研究所, 教授 (90142736)

Co-Investigator(Kenkyū-buntansha) NOMURA Naoyuki  東京医科歯科大学, 生体材料工学研究所, 准教授 (90332519)
DOI Hisashi  東京医科歯科大学, 生体材料工学研究所, 助教 (30251549)
TSUTSUMI Yusuke  東京医科歯科大学, 生体材料工学研究所, 助教 (60447498)
横山 敦郎  北海道大学, 大学院・歯学研究科, 教授 (20210627)
米山 隆之  東京医科歯科大学, 生体材料工学研究所, 助教授 (00220773)
小林 郁夫  東京医科歯科大学, 生体材料工学研究所, 助手 (40242268)
Project Period (FY) 2006 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥18,080,000 (Direct Cost: ¥15,200,000、Indirect Cost: ¥2,880,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2008: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2007: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2006: ¥5,600,000 (Direct Cost: ¥5,600,000)
Keywordsチタン / ジルコニウム / 骨形成 / リン酸カルシウム / カソード分極 / 表面分析 / マイクロアーク酸化 / チタン合金 / 骨折固定材 / 表面被覆 / 不動態皮膜
Research Abstract

Difference in the ability of calcium phosphate formation between Ti and Zr was caused by the difference in the stability of surface oxide films on both metals. Zr coating was effective to prevent calcium phosphate formation on Ti. On the other hand, cathodic polarization of Zr in a supporting electrolyte made it possible to add the ability of calcium phosphate formation to Zr and its mechanism was elucidated. Zr coating is effective to prevent the formation of callus on Ti alloys used for internal bone fixators.

Report

(6 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report   Self-evaluation Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (81 results)

All 2010 2009 2008 2007 2006 Other

All Journal Article (19 results) (of which Peer Reviewed: 13 results) Presentation (45 results) Book (9 results) Remarks (5 results) Patent(Industrial Property Rights) (3 results)

  • [Journal Article] Difference in surface reactions between titanium and zirconium in Hanks' solution to elucidate mechanism of calcium phosphate formation on titanium using XPS and cathodic polarization2009

    • Author(s)
      Tsutsumi Y, Nishimura D, Doi H, Nomura N, Hanawa T.
    • Journal Title

      Mat Sci Eng C C29

      Pages: 1702-1708

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] In vitro short term platelet adhesion on various metals2009

    • Author(s)
      Y.Tanaka, K.Kurashima, H.Saito, A.Nagai, Y.Tsutsumi, H.Doi, N.Nomura, T.Hanawa
    • Journal Title

      Journal of artificial Organs 12

      Pages: 182-186

    • NAID

      10025351403

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An overview of biofunctionalisation of metals in Japan2009

    • Author(s)
      T.Hanawa
    • Journal Title

      Journal of Royal Society Interface 6

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Difference in surface reactions between titanium and zirconium in Hanks' solution to elucidate mechanism of calcium phosphate formation on titanium using XPS and cathodic polarization2009

    • Author(s)
      Tsutsumi Y, Nishimura D, Doi H, Nomura N, Hanawa T
    • Journal Title

      Mater Sci Eng C doi : 10.1016/j.msec

      Pages: 16-16

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Difference in surface reactions between titanium and zirconium in Hanks' solution to elucidate mechanism of calcium phosphate formation on titanium using XPS and cathodic polarization2009

    • Author(s)
      Y. Tsutsumi, D. Nishimura, H. Doi, N. Nomura, T. Hanawa
    • Journal Title

      Materials Science and Engineering C doi : 10. 1016/j. msec. 2009. 016

      Pages: 1702-1708

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 機能分子による金属の生体機能化2008

    • Author(s)
      塙隆夫
    • Journal Title

      軽金属 58

      Pages: 583-587

    • NAID

      10024390066

    • Related Report
      2008 Annual Research Report 2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Inhibition effect of zirconium coating on calcium phosphate precipitation of titanium to avoid assimilation with bone2007

    • Author(s)
      Kobayashi E, Ando M, Tsutsumi Y, Doi H, Yoneyama T, Kobayashi M, Hanawa T.
    • Journal Title

      Mater Trans 48

      Pages: 301-306

    • NAID

      10018734182

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition effect of zirconium coating on calcium phosphate precipitation of titanium to avoid assimilation with bone2007

    • Author(s)
      Kobayashi E, Ando M, Tsutsumi Y, Doi H, Yoneyama T, Kobayashi M, Hanawa T
    • Journal Title

      Mater Trans 48

      Pages: 301-306

    • NAID

      10018734182

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Calcium phosphate formation on titanium by low-voltage electrolytic treatments2007

    • Author(s)
      Tanaka Y, Kobayashi E, Hiromoto S, Asami K, Imai H, Hanawa T
    • Journal Title

      J Mater Sci Mater Med 18

      Pages: 797-806

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Corrosion behavior of zirconium based alloys in Simulated Body Fluids2007

    • Author(s)
      Tsutsumi Y, Takano Y, Doi H, Noda K, Hanawa T
    • Journal Title

      Mater Sci Forum 561-565

      Pages: 1489-1492

    • Related Report
      2008 Self-evaluation Report
  • [Journal Article] 表面改質による金属の生体適合化・機能化2007

    • Author(s)
      塙隆夫
    • Journal Title

      日本金属学会報まてりあ 46

      Pages: 203-206

    • NAID

      10018736038

    • Related Report
      2008 Self-evaluation Report
  • [Journal Article] Corrosion behavior of zirconium based alloys in simulated body fluids2007

    • Author(s)
      Y. Tsutsumi, Y. Takano, H. Doi, K. Noda, T. Hanawa
    • Journal Title

      Materials Science Forum 561-565

      Pages: 1489-1492

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Calcium phosphate formation on titanium by low-voltage electrolytic treatments2007

    • Author(s)
      Y. Tanaka, E.Kobayashi, S.Hiromoto, K. Asami, H. Imai, T. Hanawa
    • Journal Title

      Journal of Materials Science: Mater in Medicine 18

      Pages: 797-806

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition effect of zirconium coating on calcium phosphate precipitation of titanium to avoid assimilation with bone2007

    • Author(s)
      E. Kobayashi, M. Ando, Y. Tsutsumi, H. Doi, T. Yoneyama, M. Kobayashi, T. Hanawa
    • Journal Title

      Materials Transactions 48

      Pages: 301-306

    • NAID

      10018734182

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition effect of zirconium coating on calcium phosphate precipitation of titanium to avoid assimilation with bone2007

    • Author(s)
      Kobayashi E, Ando M, Tsutsumi Y, Doi H, Yoneyama T, Kobayashi M, Hanawa T
    • Journal Title

      Materials Transactions 48

      Pages: 301-306

    • NAID

      10018734182

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 表面改質による金属の生体適合化・機能化2007

    • Author(s)
      塙 隆夫
    • Journal Title

      日本金属学会会報まてりあ 46

      Pages: 203-206

    • NAID

      10018736038

    • Related Report
      2006 Annual Research Report
  • [Journal Article] バイオ金属材料2006

    • Author(s)
      塙隆夫
    • Journal Title

      材料の科学と工学 43

      Pages: 150-155

    • NAID

      10024352057

    • Related Report
      2008 Self-evaluation Report
  • [Journal Article] バイオ金属材料2006

    • Author(s)
      塙 隆夫
    • Journal Title

      材料の科学と工学 43

      Pages: 150-155

    • NAID

      10024352057

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Cathodic alkaline treatment of zirconium to give the ability to form calcium phosphate

    • Author(s)
      Tsutsumi Y, Nishimura D, Doi H, Nomura N, Hanawa T.
    • Journal Title

      Acta Biomater (In press)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Presentation] カソード分極処理によるZrの硬組織適合性の改善2010

    • Author(s)
      堤祐介, 森山義久, 大家渓, 土居壽, 野村直之, 野田和彦, 塙隆夫
    • Organizer
      日本金属学会2010年春期大会
    • Place of Presentation
      つくば
    • Year and Date
      2010-03-30
    • Related Report
      2009 Final Research Report
  • [Presentation] 電気化学的表面処理による金属材料の生体適合性付与2010

    • Author(s)
      堤祐介, 大家渓, 土居壽, 野村直之, 塙隆夫
    • Organizer
      第4回バイオ・ナノテクフォーラムシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-03-03
    • Related Report
      2009 Final Research Report
  • [Presentation] Difference in surface property between titanium and zirconium and cathodic alkaline treatment2009

    • Author(s)
      Tsutsumi Y, Hanawa T.
    • Organizer
      9th Asian BioCeramics Symposium (ABC2009)
    • Place of Presentation
      Nagoya Congress Center, Nagoya, Japan
    • Year and Date
      2009-12-11
    • Related Report
      2009 Final Research Report
  • [Presentation] 骨芽細胞様細胞の遺伝子発現の金属の種類による相違2009

    • Author(s)
      大家渓, 竹村太郎, 堤祐介, 土居壽, 野村直之, 花方信孝, 塙隆夫
    • Organizer
      第31回日本バイオマテリアル学会大会
    • Place of Presentation
      京都
    • Year and Date
      2009-11-17
    • Related Report
      2009 Final Research Report
  • [Presentation] Zrの硬組織適合性へ及ぼすカソード分極処理の影響2009

    • Author(s)
      森山義久, 大家渓, 堤祐介, 土居壽, 野村直之, 野田和彦, 塙隆夫
    • Organizer
      第31回日本バイオマテリアル学会大会
    • Place of Presentation
      京都
    • Year and Date
      2009-11-17
    • Related Report
      2009 Final Research Report
  • [Presentation] 電気化学的手法による生体用金属材料の生体機能化2009

    • Author(s)
      堤祐介, 大家渓, 土居壽, 野村直之, 塙隆夫
    • Organizer
      第31回日本バイオマテリアル学会大会
    • Place of Presentation
      京都
    • Year and Date
      2009-11-16
    • Related Report
      2009 Final Research Report
  • [Presentation] Calcium phosphate formation on titanium and zirconium and its application to medical devices2009

    • Author(s)
      Hanawa T.
    • Organizer
      22nd International Symposium on Ceramics in Medicine
    • Place of Presentation
      Hotel Inter-Burgo, Daegu, Korea
    • Year and Date
      2009-10-27
    • Related Report
      2009 Final Research Report
  • [Presentation] Calcium phosphate formation on titanium and zirconium and its application to medical devices, Invited Talk2009

    • Author(s)
      T.Hanawa
    • Organizer
      22nd International Symposium on Ceramics in Medicine
    • Place of Presentation
      Hotel Inter-Burgo, Daegu, Korea
    • Year and Date
      2009-10-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] Titanium alloys and their surfaces2009

    • Author(s)
      Hanawa T.
    • Organizer
      11th Dental Implantology, Hotel Continental
    • Place of Presentation
      Burno, Czech
    • Year and Date
      2009-10-02
    • Related Report
      2009 Final Research Report
  • [Presentation] MC3T3-E1細胞の骨分化における金属の種類による遺伝子発現の差異2009

    • Author(s)
      大家渓, 堤祐介, 土居壽, 野村直之, 塙隆夫
    • Organizer
      第54回日本歯科理工学会学術講演会
    • Place of Presentation
      鹿児島
    • Year and Date
      2009-10-01
    • Related Report
      2009 Final Research Report
  • [Presentation] マイクロアーク酸化処理によるジルコニウムの硬組織適合性の改善2009

    • Author(s)
      堤祐介, 河晶充, 土居壽, 野村直之, 金教漢, 塙隆夫
    • Organizer
      日本金属学会2009年秋期(第145回)大会
    • Place of Presentation
      京都
    • Year and Date
      2009-09-17
    • Related Report
      2009 Final Research Report
  • [Presentation] チタン, ジルコニウム, 金における骨芽細胞様細胞骨分化特性の網羅的遺伝子発現解析2009

    • Author(s)
      大家渓, 竹村太郎, 花方信孝, 森山義久, 野田和彦, 堤祐介, 土居壽, 野村直之, 塙隆夫
    • Organizer
      日本金属学会2009年秋期(第145回)大会
    • Place of Presentation
      京都
    • Year and Date
      2009-09-17
    • Related Report
      2009 Final Research Report
  • [Presentation] ジルコニウム上での骨形成を促進するカソード分極処理法2009

    • Author(s)
      堤祐介
    • Organizer
      次世代医療システム産業化フォーラム
    • Place of Presentation
      大阪
    • Year and Date
      2009-09-15
    • Related Report
      2009 Final Research Report
  • [Presentation] 陽極酸化処理によるジルコニウムの硬組織適合性の向上2009

    • Author(s)
      堤祐介, ハジュンユン, 土居壽, 野村直之, キムキョウハン, 塙隆夫
    • Organizer
      日本機械学会2009年度年次大会
    • Place of Presentation
      盛岡
    • Year and Date
      2009-09-15
    • Related Report
      2009 Final Research Report
  • [Presentation] カソード分極処理を施したZrの擬似体液中におけるリン酸カルシウム形成能評価2009

    • Author(s)
      森山義久, 今井八郎, 塙隆夫, 野村直之, 土居壽, 堤祐介
    • Organizer
      日本金属学会2009年春期(第143回)大会
    • Place of Presentation
      東京
    • Year and Date
      2009-03-30
    • Related Report
      2009 Final Research Report
  • [Presentation] Calcium phosphate formation mechanism on titanium2008

    • Author(s)
      Hanawa T.
    • Organizer
      The Seventh International Symposium on Biomaterials, Kyngpook National University
    • Place of Presentation
      Deague, Korea
    • Year and Date
      2008-12-01
    • Related Report
      2009 Final Research Report
  • [Presentation] Difference in surface reactions between titanium and zirconium in Hanks' solution to elucidate mechanism of calcium phosphate formation on titanium2008

    • Author(s)
      Hanawa T
    • Organizer
      The 7th International Symposium on Biomaterials
    • Place of Presentation
      Kyungpook National University, Deagu, Korea
    • Year and Date
      2008-12-01
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] Difference in surface reactions between titanium and zirconium in Hanks' solution to elucidate mechanism of calcium phosphate formation on titanium2008

    • Author(s)
      T. Hanawa
    • Organizer
      The 7th International Symposium on Biomaterials
    • Place of Presentation
      Kyungpook National Univ, Deagu, Korea
    • Year and Date
      2008-12-01
    • Related Report
      2008 Annual Research Report
  • [Presentation] Zirconium coating on titanium for inhibition of assimilation with bone2008

    • Author(s)
      Hanawa T, Nishimura D, Tsutsumi Y, Doi H, Nomura N.
    • Organizer
      8th World Biomaterials Congress
    • Place of Presentation
      Amsterdam, Netherlands
    • Year and Date
      2008-05-30
    • Related Report
      2009 Final Research Report
  • [Presentation] Bone differentiation property of osteoblast-like cells on metals2008

    • Author(s)
      Oya K, Sakamoto H, Tanaka Y, Kimura T, Tsutsumi Y, Doi H, Hanawa T.
    • Organizer
      8th World Biomaterials Congress
    • Place of Presentation
      Amsterdam, Netherlands
    • Year and Date
      2008-05-30
    • Related Report
      2009 Final Research Report
  • [Presentation] 整形外科における金属材料2008

    • Author(s)
      塙隆夫
    • Organizer
      第81回日本整形外科学会総会教育研修講演
    • Place of Presentation
      札幌
    • Year and Date
      2008-05-25
    • Related Report
      2009 Final Research Report
  • [Presentation] 整形外科における金属材料2008

    • Author(s)
      塙隆夫
    • Organizer
      第81 回日本整形外科学会総会教育研修講演
    • Place of Presentation
      札幌教育分化会館, 札幌
    • Year and Date
      2008-05-25
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] チタン, ジルコニウム, 金のMC3T3-E1細胞骨分化特性の差異2008

    • Author(s)
      大家渓, 坂本晴美, 堤祐介, 土居壽, 塙隆夫
    • Organizer
      第51回日本歯科理工学会学術講演会
    • Place of Presentation
      鶴見
    • Year and Date
      2008-04-26
    • Related Report
      2009 Final Research Report
  • [Presentation] チタンおよびジルコニウム表面におけるリン塩生成機構の解明2008

    • Author(s)
      西村大地, 堤祐介, 土居壽, 塙隆夫
    • Organizer
      日本金属学会2008年春期(第142回)大会
    • Place of Presentation
      東京
    • Year and Date
      2008-03-28
    • Related Report
      2009 Final Research Report
  • [Presentation] ジルコニウム表面でのリン酸カルシウム形成促進2008

    • Author(s)
      西村大地, 堤祐介, 土居壽, 塙隆夫
    • Organizer
      日本金属学会2008年春期(第142回)大会公募シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-03-27
    • Related Report
      2009 Final Research Report
  • [Presentation] 金属の種類による骨芽細胞様細胞の骨分化特性の差異2008

    • Author(s)
      大家渓, 坂本晴美, 能城一矢, 竹村太郎, 花方信孝, 木村剛, 堤祐介, 土居壽, 塙隆夫
    • Organizer
      日本金属学会2008年春期(第142回)大会
    • Place of Presentation
      東京
    • Year and Date
      2008-03-27
    • Related Report
      2009 Final Research Report
  • [Presentation] 電気化学的手法によるチタンとジルコニウムのリン酸カルシウム形成促進処理2008

    • Author(s)
      堤祐介, 西村大地, 土居壽, 小林郁夫, 塙隆夫
    • Organizer
      第21回歯科チタン学会学術講演会
    • Place of Presentation
      徳島
    • Year and Date
      2008-02-16
    • Related Report
      2009 Final Research Report
  • [Presentation] 金属の種類による骨芽細胞様細胞の骨分化特性の差異2008

    • Author(s)
      大家渓, 坂本晴美, 能城一矢, 竹村太郎, 花方信孝, 木村剛, 堤祐介, 土居壽, 塙隆夫
    • Organizer
      日本金属学会2008 年春期(第142回)大会
    • Place of Presentation
      東京
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] 金のMC3T3-E1 細胞骨分化特性の差異2008

    • Author(s)
      大家渓, 坂本晴美, 堤祐介, 土居壽, 塙隆夫., チタン ジルコニウム
    • Organizer
      第51 回日本歯科理工学会学術講演会
    • Place of Presentation
      鶴見
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] 骨芽細胞様細胞骨分化特性の金属における相違2007

    • Author(s)
      大家渓, 田中裕生子, 坂本晴美, 木村剛, 堤祐介, 土居壽, 岸田晶夫, 塙隆夫
    • Organizer
      第29回日本バイオマテリアル学会大会
    • Place of Presentation
      大阪
    • Year and Date
      2007-11-26
    • Related Report
      2009 Final Research Report
  • [Presentation] Ti表面での骨形成を防止するZr被覆2007

    • Author(s)
      西村大地, 堤祐介, 小林郁夫, 土居壽, 塙隆夫
    • Organizer
      第29回日本バイオマテリアル学会大会
    • Place of Presentation
      大阪
    • Year and Date
      2007-11-26
    • Related Report
      2009 Final Research Report
  • [Presentation] 機能分子固定化によるチタンの生体機能化2007

    • Author(s)
      塙隆夫
    • Organizer
      軽金属学会第113 回秋期大会基調講演
    • Place of Presentation
      千葉大学, 千葉
    • Year and Date
      2007-11-11
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] Bio-functionalization of metals with surface modification2007

    • Author(s)
      Hanawa T, Sakamoto H, Yuta T
    • Organizer
      The Sixth Pacific Rim International Conference on Advanced Materials and Processing (PRICM6)
    • Place of Presentation
      ICC Jeju, Jeju Island, Korea
    • Year and Date
      2007-11-08
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] Bio-functionalization of metals with surface modification2007

    • Author(s)
      T. Hanawa, H. Sakamoto, . Tanaka
    • Organizer
      The Sixth Pacific Rim International Conferenceon Advanced Materials and Processing (PRICM6)
    • Place of Presentation
      ICC Jeju, Jeju Island, Korea
    • Year and Date
      2007-11-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] 金属とリン酸カルシウム2007

    • Author(s)
      塙隆夫
    • Organizer
      第17回無機リン化学討論会
    • Place of Presentation
      札幌
    • Year and Date
      2007-10-02
    • Related Report
      2009 Final Research Report
  • [Presentation] 金属とリン酸カルシウム2007

    • Author(s)
      塙隆夫
    • Organizer
      第17回無機リン化学討論会依頼講演
    • Place of Presentation
      JSTイノベーションプラザ北海道, 札幌
    • Year and Date
      2007-10-02
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] 電気化学処理によるジルコニウム表面でのリン酸カルシウム形成2007

    • Author(s)
      堤祐介, 西村大地, 土居壽, 小林郁夫, 塙隆夫
    • Organizer
      日本金属学会2007年秋期 (第141回) 大会
    • Place of Presentation
      岐阜
    • Year and Date
      2007-09-20
    • Related Report
      2009 Final Research Report
  • [Presentation] Effect of homogenization treatment on corrosion resistance of Zr based alloys2007

    • Author(s)
      Tsutsumi Y, Takano Y, Doi H, Noda K, Hanawa T.
    • Organizer
      6th International Symposium on Titanium in Dentistry
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2007-06-05
    • Related Report
      2009 Final Research Report
  • [Presentation] Elucidation of phosphate precipitation mechanism on Ti and Zr by cathodic polarization in Hanks' solution2007

    • Author(s)
      Nishimura D, Doi H, Tsutsumi Y, Hanawa T, Kobayashi E.
    • Organizer
      6th International Symposium on Titanium in Dentistry
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2007-06-05
    • Related Report
      2009 Final Research Report
  • [Presentation] TiおよびZrの擬似体液中におけるカソード分極によるリン酸塩析出機構の検討2007

    • Author(s)
      西村大地, 堤祐介, 小林郁夫, 土居壽, 塙隆夫
    • Organizer
      日本金属学会2007年春季 (第140回) 大会
    • Place of Presentation
      習志野
    • Year and Date
      2007-03-29
    • Related Report
      2009 Final Research Report
  • [Presentation] 金属の生体機能化と生体適合化2007

    • Author(s)
      塙隆夫
    • Organizer
      日本金属学会第140回大会シンポジウムS1「スマート&ハーモニックバイオマテリアル」基調講演
    • Place of Presentation
      千葉工大, 習志野
    • Year and Date
      2007-03-28
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] Ti合金製内固定材表面の仮骨形成を防止する表面処理2007

    • Author(s)
      西村大地, 小林郁夫, 堤祐介, 土居壽, 塙隆夫
    • Organizer
      第1回バイオ・ナノテクフォーラム
    • Place of Presentation
      東京
    • Year and Date
      2007-03-20
    • Related Report
      2009 Final Research Report
  • [Presentation] 再生医療のための金属の生体機能化2007

    • Author(s)
      塙隆夫
    • Organizer
      第6回日本再生医療学会総会シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2007-03-14
    • Related Report
      2009 Final Research Report
  • [Presentation] 生体環境での金属の信頼性を向上させる表面技術2007

    • Author(s)
      塙隆夫
    • Organizer
      表面技術協会第115回講演大会
    • Place of Presentation
      東京
    • Year and Date
      2007-03-08
    • Related Report
      2009 Final Research Report
  • [Presentation] 金属の生体機能化と生体適合化2007

    • Author(s)
      塙隆夫
    • Organizer
      日本金属学会2007年春季 (第140回) 大会
    • Place of Presentation
      習志野
    • Related Report
      2009 Final Research Report
  • [Book] 医療用金属材料概論2010

    • Author(s)
      塙隆夫編
    • Total Pages
      278
    • Publisher
      日本金属学会
    • Related Report
      2009 Annual Research Report
  • [Book] 第2章 金属系バイオマテリアル 材料学シリーズ 生体材料2008

    • Author(s)
      塙隆夫
    • Publisher
      内田老鶴圃
    • Related Report
      2009 Final Research Report
  • [Book] 総論3.2 金属材料, 生体材料, 環境調和型新材料シリーズ(日本セラミックス協会編)2008

    • Author(s)
      塙隆夫
    • Publisher
      日刊工業新聞社
    • Related Report
      2009 Final Research Report
  • [Book] 第2章 金属系バイオマテリアル, 材料学シリーズ, よくわかる生体材料(田中, 順三, 角田, 方衛, 立石, 哲也)2008

    • Author(s)
      塙隆夫
    • Publisher
      内田老鶴圃
    • Related Report
      2008 Self-evaluation Report
  • [Book] 材料学シリーズ, バイオマテリアル2008

    • Author(s)
      塙隆夫
    • Total Pages
      56
    • Publisher
      内田老鶴圃
    • Related Report
      2008 Annual Research Report
  • [Book] 金属バイオマテリアル2007

    • Author(s)
      塙隆夫, 米山隆之
    • Publisher
      コロナ社
    • Related Report
      2009 Final Research Report 2008 Self-evaluation Report
  • [Book] 金属バイオマテリアル2007

    • Author(s)
      塙 隆夫、米山隆之
    • Total Pages
      158
    • Publisher
      コロナ社
    • Related Report
      2007 Annual Research Report
  • [Book] 2.3.4チタン, 3.12インプラントと微量元素, 生命元素事典(桜井 弘編)2006

    • Author(s)
      塙隆夫
    • Publisher
      オーム社
    • Related Report
      2009 Final Research Report
  • [Book] バイオマテリアルとしての金属材料, 再生医療のためのバイオマテリアル, 再生医療の基礎シリーズ2006

    • Author(s)
      塙隆夫
    • Publisher
      コロナ社
    • Related Report
      2009 Final Research Report
  • [Remarks] ホームページ等

    • URL

      http://www.tmd.ac.jp/i-mde/www/index.html

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.tmd.ac.jp/i-mde/www/index.html

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.tmd.ac.jp/i-mde/www/index.Html

    • Related Report
      2008 Self-evaluation Report
  • [Remarks]

    • URL

      http://www.tmd.ac.jp/i-mde/www/index.html

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://www.tmd.ac.jp/i-mde/www/index.html

    • Related Report
      2007 Annual Research Report
  • [Patent(Industrial Property Rights)] 硬組織接触具用材の製造方法、及び硬組織接触具2010

    • Inventor(s)
      堤祐介, 塙隆夫
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Filing Date
      2010-04-23
    • Related Report
      2009 Final Research Report
  • [Patent(Industrial Property Rights)] 硬組織接触具用材の製造方法、及び硬組織接触具2008

    • Inventor(s)
      堤祐介, 塙隆夫
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Filing Date
      2008-09-05
    • Related Report
      2009 Final Research Report
  • [Patent(Industrial Property Rights)] 硬組織接触具用材の製造方法、及び硬組織接触具2007

    • Inventor(s)
      堤祐介, 塙隆夫
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Industrial Property Number
      2007-241100
    • Filing Date
      2007-09-18
    • Related Report
      2009 Final Research Report

URL: 

Published: 2006-04-01   Modified: 2016-04-21  

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