Surface treatments of bone fixators consiting of titanium alloys to inhibit the formation of callus
| Project/Area Number |
18300160
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
HANAWA Takao Tokyo Medical and Dental University, 生体材料工学研究所, 教授 (90142736)
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| Co-Investigator(Kenkyū-buntansha) |
NOMURA Naoyuki 東京医科歯科大学, 生体材料工学研究所, 准教授 (90332519)
DOI Hisashi 東京医科歯科大学, 生体材料工学研究所, 助教 (30251549)
TSUTSUMI Yusuke 東京医科歯科大学, 生体材料工学研究所, 助教 (60447498)
横山 敦郎 北海道大学, 大学院・歯学研究科, 教授 (20210627)
米山 隆之 東京医科歯科大学, 生体材料工学研究所, 助教授 (00220773)
小林 郁夫 東京医科歯科大学, 生体材料工学研究所, 助手 (40242268)
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| Project Period (FY) |
2006 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥18,080,000 (Direct Cost: ¥15,200,000、Indirect Cost: ¥2,880,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2008: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2007: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2006: ¥5,600,000 (Direct Cost: ¥5,600,000)
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| Keywords | チタン / ジルコニウム / 骨形成 / リン酸カルシウム / カソード分極 / 表面分析 / マイクロアーク酸化 / チタン合金 / 骨折固定材 / 表面被覆 / 不動態皮膜 |
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| Research Abstract |
Difference in the ability of calcium phosphate formation between Ti and Zr was caused by the difference in the stability of surface oxide films on both metals. Zr coating was effective to prevent calcium phosphate formation on Ti. On the other hand, cathodic polarization of Zr in a supporting electrolyte made it possible to add the ability of calcium phosphate formation to Zr and its mechanism was elucidated. Zr coating is effective to prevent the formation of callus on Ti alloys used for internal bone fixators.
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Report
(6 results)
Research Products
(80 results)
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[Presentation] チタン, ジルコニウム, 金における骨芽細胞様細胞骨分化特性の網羅的遺伝子発現解析2009
Author(s)
大家渓, 竹村太郎, 花方信孝, 森山義久, 野田和彦, 堤祐介, 土居壽, 野村直之, 塙隆夫
Organizer
日本金属学会2009年秋期(第145回)大会
Place of Presentation
京都
Year and Date
2009-09-17
Related Report
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[Presentation] 金属とリン酸カルシウム2007
Author(s)
塙隆夫
Organizer
第17回無機リン化学討論会依頼講演
Place of Presentation
JSTイノベーションプラザ北海道, 札幌
Year and Date
2007-10-02
Related Report
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