| Budget Amount *help |
¥12,480,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥2,280,000)
Fiscal Year 2009: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2008: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2007: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2006: ¥2,600,000 (Direct Cost: ¥2,600,000)
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| Research Abstract |
We have investigated bystander chromosomal damage in primary normal human bronchial epithelial cells irradiated with low-energy He-ion beams. When the unirradiated cells were kept with He-ion irradiated cells on the dishes, bystander chromosomal effect was observed in the unirradiated bystander cells. Chromatid-type fragments, such as chromatid break, acentric fragment, isochromatid deletion and interchromatin exchange, were observed in the direct hit cells. On the other hand, only chromatid breaks and acentric fragments were observed in the bystander cells. There is evidence that simple chromosomal damage occur in bystander chromosomal effect.
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