Genome analysis of bacteria inhabiting the mucosal surface of intestine

• Project/Area Number: 18310132
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: 基礎ゲノム科学
• Research Institution: University of Miyazaki
• Principal Investigator: HAYASHI Tetsuya University of Miyazaki, FRONTIER SCIENCE RESEARCH CENTER, PROFESSOR (10173014)
• Co-Investigator(Kenkyū-buntansha): NAKAYAMA Keisuke UNIERSITY OF MIYAZAKI, FACULTY OF MEDICINE, ASSISTANT PROFESSOR (10347057) ; OGURA Yoshitoshi UNIERSITY OF MIYAZAKI, FRONTIER SCIENCE RESEARCHCENTER, ASSISTANT PROFESSOR (40363585) ; OOKA Tadasuke UNIERSITY OF MIYAZAKI, FACULTY OF MEDICINE, ASSISTANT PROFESSOR (50363594) ; KUWAHARA Tomomi UNIVERSITY OF TOKUSHIMA, INSTITUTE OF HEALTH BIOSCIENCES, Associate Professor (60263810) ; KUROKAWA Ken NARA INSTITUTE OF SCIENCE AND TECHNOLOGY, LABORATORY OF COMPARATIVE GENOMICS, ASSOCIATE PROFESSOR (20343246)
• Project Period (FY): 2006 – 2007
• Project Status: Completed (Fiscal Year 2007)
• Budget Amount: ¥17,490,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥1,890,000); Fiscal Year 2007: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000); Fiscal Year 2006: ¥9,300,000 (Direct Cost: ¥9,300,000)
• Keywords: Genetics / Gut microbiota / Genome / Metagenome / Unculturable bacteria / 難培養性

Research Abstract

The final goal of our research is to clarify the compositional and genomic features of gut microbiota and their positional differences. However, it is impossible to know the positional differences by metagenomic analysis of fecal samples. We need to analyze the samples that are obtained directly from intestine, but such sampling in human is accompanied by many technical and ethical problems. Therefore, the mouse intestine was used as a model system in our study. In the present research project, we focused on the microbiota residing on the mucosal surface, which are obviously playing most important roles in term of host-resident microbe interaction, particularly on genome sequence determination of segmented filamentous bacterium (SFB). SFB is an unculturable bacterium which appears on the mucosal surface as a dominant bacterial species during the period of weaning.
We first isolated about 5,000 SFB cells from the intestine of weanling mice by a micromanipulator, amplified their genomic DNA by rolling circle amplification, and tried to determine the sequence by the random shotgun sequencing method. However, we found that plasmid DNA was preferentially amplified, and thus, it is very hard to determine the whole genome sequence by this strategy. Therefore, we cultivated SFB cells in gnotobiotic mice, and prepare their DNA for genome sequencing. We then constructed a random shotgun library of SFB, and generated about 50,000 shotgun reads. Contamination of DNA derived from other bacterial species severely disturbed our analysis, but by PCR-based gap closing, we have obtained 50 super-contigs. For the final finishing process, we have re-isolated SFB cells and prepared a BAC library. Currently, we are determining the end-sequences of 1,200 BAC clones for the final finishing process. The approach we employed in this study is a new strategy for the genome analysis of unculturable bacteria in gut microbiota.

Research Products

• [Journal Article] Distribution,functional expression genetic organization of Cif,a phage-encoded type III-secreted effector from enteropathogenic and enterohaemorragic Escherichia coli (2008)
  • Author(s): Loukiadis E., et. al.
  • Journal Title: J.Bacteriol. 190(1) Pages: 275-285
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Enteropathogenic Escherichia coli(EPEC)O125:H6 triggers attaching and effacing lesions on human intestinal biopsies independently of Nck (2008)
  • Author(s): Bai L., et. al.
  • Journal Title: Infect.Immun. 76(1) Pages: 361-368
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Global regulation by horizontally transferred regulators establishes the pathogenicity of Escherichia coli (2008)
  • Author(s): Abe H., et. al.
  • Journal Title: DNA Res. 15(1) Pages: 25-38
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Genomic comparison of the O-antigen biosynthesis gene clusters of Escherichia coli O55 strains belonging to three distinct lineages (2008)
  • Author(s): Iguchi A., et. al.
  • Journal Title: Microbiology 154(2) Pages: 559-570
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] High-level fluoroquinolone resistance in ophthalmic clinical isolates belonging to the species Corynebacterium macginleyi (2008)
  • Author(s): Eguchi H., et. al.
  • Journal Title: J.Clin.Microbiol. 46(2) Pages: 527-532
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Comparative genomic analysis using microarray demonstrates strong correlation between presence of Vp-PAI and pathogenicity in Kanagawa phenomenon-positive Vibrio parahaemolyticus (2008)
  • Author(s): Izutsu, K., et. al.
  • Journal Title: Infect.Immun. 76(3) Pages: 1016-1023
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Complete DNA sequence and analysis of the transferable multiple drug resistance plasmids(R-plasmids)from Photobacterium damselae subsp.Piscicida isolated in Japan and USA (2008)
  • Author(s): Kim MJ, et. al.
  • Journal Title: Antimicrob.Agents Chemother 52 Pages: 606-611
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] メタゲノム解析-微生物集団のゲノムをまとめて解析するということ (2008)
  • Author(s): 林 哲也
  • Journal Title: 現代化学 444 Pages: 40-42
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Distribution, functional expression genetic organization of Cif, a phage-encoded type III-secreted effector from enteropathogenic and enterohaemorragic Escherichia coli (2008)
  • Author(s): Loukiadis, K., Nobe, R., Herold S., Tramuta, C., Ogura, Y., Ooka, T., Morabito, S., Kerouredan, M., Brugere, H., Schmidt, H., Hayashi, T., Oswald, E
  • Journal Title: J. Bacteriol 190(1) Pages: 275-285
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Enteropathogenic Escherichia coli(EPEC) O125 : H6 triggers attaching and effacing lesions on human intestinal biopsies independently of Nck (2008)
  • Author(s): Bai, L., Schukker, S., Whale, A., Mousnier, A., Marches, O., Wang, L., Ooka, X., Heuschkel, R., Kaper, JB., Gomes, TSK., Xu, J., Phillips, AD., Frankel, G
  • Journal Title: Infect. Immun 76(1) Pages: 361-368
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Global regulation by horizontally transferred regulators establishes the pathogenicity of Escherichia coli (2008)
  • Author(s): Abe, H., Miyahara, A., Oshima, T., Tashiro, K., Ogura, Y., Kuhara, S., Ogasawara, N., Hayashi, T., Tobe, T
  • Journal Title: DNA Res 15(1) Pages: 25-38
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Genomic comparison of the O-antigen biosynthesis gene clusters of Escherichia coli O55 strains belonging to three distinct lineages (2008)
  • Author(s): Iguchi, A., Ooka, T., Ogura, Y., Asadulghani, K., Nakayama, G., Frankel, G., Hayashi, T
  • Journal Title: Microbioloev 154(2) Pages: 559-570
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] High-level fluoroquinolone resistance in ophthalmic clinical isolates belonging to the species Corynebacterium macginleyi (2008)
  • Author(s): Eguchi, H., Kuwahara, X., Miyamoto, X., Nakayama-Imaohji, H., Ichimura, M., Hayashi, X., Shiota, H
  • Journal Title: J. Clin. Microbiol. 46(2) Pages: 527-532
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Comparative genomic analysis using microarray demonstrates strong correlation between presence of Vp-PAI and pathogenicity in Kanagawa phenomenon-positive Vibrio parahaemolyticus (2008)
  • Author(s): Izutsu, K., Kurokawa, K., Tashiro, K., Kuhara, S., Hayashi, T., Honda, T., Iida, T
  • Journal Title: Infect. Immun. 76(3) Pages: 1016-1023
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Complete DNA sequence and analysis of the transferable multiple drug resistance plasmids(R-plasmids) from Photobacterium damselae subsp. Piscicida isolated in Japan and USA (2008)
  • Author(s): Kim, MJ., Hirono, I., Kurokawa, K., Maki, T., Hawke, J., Kondo, H., Santos, M., Aoki, T
  • Journal Title: Antimicrob. Agents Chemother 52 Pages: 606-611
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Distribution, functional expression genetic organization of Cif, aphage-encoded type III-secreted effector from enteropathogenic and enterohaemorragic Escherichia coli. (2008)
  • Author(s): Loukiadis E., et. al.
  • Journal Title: J. Bacteriol. 190(1) Pages: 275-285
  • Peer Reviewed
• [Journal Article] Enteropathogenic Escherichia coli (EPEC) O125: H6 triggers attaching and effacing lesions on human intestinal biopsies independently of Nck (2008)
  • Author(s): Bai L., et. al.
  • Journal Title: Infect. Immun. 76(1) Pages: 361-368
  • Peer Reviewed
• [Journal Article] High-level fluoroquinolone resistance in ophthalmic clinical isolates belonging to the species Corynebacterium macginleyi (2008)
  • Author(s): Eguchi H., et. al.
  • Journal Title: J. Clin. Microbiol. 46(2) Pages: 527-532
  • Peer Reviewed
• [Journal Article] Comparative genomic analysis using microarray demonstrates strong correlation between presence of Vp-PAI and pathogenicity in Kanagawa phenomenon-positive Vibrio parahaemolyticus. (2008)
  • Author(s): Izutsu, K., et. al.
  • Journal Title: Infect. Immum. 76(3) Pages: 1016-1023
  • Peer Reviewed
• [Journal Article] Complete DNA sequence and analysis of the transferable multiple drug resistance plasmids (R-plasmids) from Photobacterium damselae subsp. Piscicida isolated in Japan and USA. (2008)
  • Author(s): Kim MJ, et. al.
  • Journal Title: Antimicrob. Agents Chemother 52 Pages: 606-611
  • Peer Reviewed
• [Journal Article] RNA polymerase b-subunit gene(rpoB)sequence analysis for the identification of Bacteroides spp (2007)
  • Author(s): Ko K.S., et. al.
  • Journal Title: Clin.Microbiol.Infect. 13 Pages: 48-54
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] TccP2 of O157:H7 and non-0157 enterohemorrhagic Escherichia coli(EHEC):challenging the dogma of EHEC-induced actin polymerization (2007)
  • Author(s): Ogura Y., et. al.
  • Journal Title: Infect.Immun 75(2) Pages: 604-612
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Characterization of tccP2 carried by atypical ENTEROPATHOGENIC Escherichia colt (2007)
  • Author(s): Ooka T., et. al.
  • Journal Title: FEMS Microbiol.Lett 271 Pages: 126-135
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] TccP2-mediated subversion of actin dynamics by EPEC2 - a distinct evolutionary lineage of ENTEROPATHOGENIC Escherichia coli (2007)
  • Author(s): Whale A., et. al.
  • Journal Title: Microbiology 153 Pages: 1743-1755
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] An improved DNA isolation method for metagenomic analysis of the microbial flora of the human intestine (2007)
  • Author(s): Morita H., et. al.
  • Journal Title: Microbes Environ. 22(3) Pages: 214-222
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Extensive genomic diversity and selective conservation of virulence-determinants in enterohaemorrhagic Escherichia coli strains of O157 and non-O157 serotypes (2007)
  • Author(s): Ogura Y., et. al.
  • Journal Title: Genome Biol. 8(7)
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Distribution of stable DnaA-binding sites on the Bacillus Subtilis genome detected using a modified ChIP-chip method (2007)
  • Author(s): Ishikawa S., et. al.
  • Journal Title: DNA Res. 14 Pages: 155-168
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes (2007)
  • Author(s): Kurokawa K., et. al.
  • Journal Title: DNA Res. 14 Pages: 169-181
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Modifying effects of fermented brown rice on fecal microbiota in rats (2007)
  • Author(s): Kataoka, K., et. al.
  • Journal Title: Anaerobe 13 Pages: 220-227
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Vibrionaceae;versatile bacterial family with evolutionary conserved variability (2007)
  • Author(s): Dryselius, R., et. al.
  • Journal Title: Res.Microbiol. 158 Pages: 479-486
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] The entire organization of transcription unites on the Bacillus subtilis genome (2007)
  • Author(s): Kobayashi, H., et. al.
  • Journal Title: BMC Genomics 8 Pages: 197-201
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Analysis of invariant sequences in 266 complete genomes (2007)
  • Author(s): Goto, N., et. al.
  • Journal Title: Gene 401 Pages: 172-180
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] 微生物における比較ゲノム研究の進展 (2007)
  • Author(s): 林 哲也
  • Journal Title: 実験医学 25(2) Pages: 266-272
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] ヒト腸内細菌叢のゲノムシークエンス (2007)
  • Author(s): 服部 正平, 他
  • Journal Title: 腸内細菌学雑誌 21(3) Pages: 187-197
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] メタゲノミクスのバイオインフォマティクス (2007)
  • Author(s): 黒川 顕
  • Journal Title: 化学と生物 45 Pages: 495-501
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Comparative genomics : genome configuration and the driving forces in the evolution of vibrios (2007)
  • Author(s): Iida, T., Kurokawa, K
  • Journal Title: Clin. Microbiol. Infect 13 Pages: 48-54
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] RNA polymerase b-subunit gene(rpoB) sequence analysis for the identification of Bacteroides spp (2007)
  • Author(s): Ko, K.S., Kuwahara, T., Haehwa, L., Yoon, Y.J., Kim, B.J., Lee, H. K, Ohnishi, Y., Kook, Y.H
  • Journal Title: Infect. Immun 75(2) Pages: 604-612
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] TccP2 of O1 57 : H7 and non-O157 enterohemorrhagic Escherichia coli(EHEC) : challenging the dogma of EHEC-induced actin p ol ymeri zati on (2007)
  • Author(s): Ogura, Y., Ooka, T., Whale, A., Garmendia, J., Beutin, L., Tennant, S., Krause, G., Morabito, S., Chinen, I., Tobe, T., Abe, H., Tozzoli, R., Caprioli, A., Rivas, M., Browne, R. R., Hayashi, T., Frankel, G
  • Journal Title: FEMS Microbiol. Lett 271 Pages: 126-135
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Characterization of tccP2 carried by atypical enteropathogenic Escherichia coli (2007)
  • Author(s): Ooka, T., Vieira, MA., Ogura, Y., Beutin, L., Ragione, R. L., van Diemen, P. M., Stevens, M. P., I., Aktan, S., Cawthraw, Best, A., Hemandes, R. T., Krause, G., Gomes, T. A. T, Hayashi, T., Frankel, G
  • Journal Title: Microbiology 153 Pages: 1743-1755
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] TccP2-mediated subversion of actin dynamics by EPEC 2 - a distinct evolutionary lineage of enteropathogenic Escherichia coli. (2007)
  • Author(s): Whale, A., Hernandes, RT., Ooka, T., Krause, G., Schuller, S., Garmendia, J., Crowther, L., Vieira, MA., Ogura, Y., Phillips, AD., Beutin, L., Gomes, TA., Hayashi, T., Frankel, G
  • Journal Title: Microbes Environ 22(3) Pages: 214-222
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] An improved DNA isolation method for metagenomic analysis of the microbial flora of the human intestine (2007)
  • Author(s): Morita, H., Kuwahara, X., Okushima, K., Sasamoto, H., Itoh, K., Hattori, M., Hayashi, X., Takami, H
  • Journal Title: Genome Biol 8(7)
  • NAID: 110006379878
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Extensive genomic diversity and selective conservation of virulence-determinants in enterohaemorrhagic Escherichia coli strains of O157 and non-O157 serotypes (2007)
  • Author(s): Ogura, Y., Ooka Asadulghani., A., Terajima, J, Nougayrede, J-R., Kurokawa, K., Tashiro, K., Tobe, T., Nakayama, K., Kuhara, S., Oswald, E., Watanabe, H., Hayashi, T
  • Journal Title: DNARes 14 Pages: 155-168
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Distribution of stable DnaA-binding sites on the Bacillus Subtilis genome detected using a modified ChIP-chip method (2007)
  • Author(s): Ishikawa, S., Ogura, Y., Yoshimura, M., Okumura, H., Cho, E., Kawai, Y., Kurokawa, K., Oshima, T., Ogasawara, N
  • Journal Title: DNA Res 14 Pages: 169-181
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes (2007)
  • Author(s): Kurokawa, K., Itoh, T., Kuwahara, T., Oshima, K., Toh, H., Toyoda, A., Takami, H., Morita, H., Sharma, VK., Srivastava, TR, Taylor, TD., Noguchi, D., Mori, H., Ogura, Y., Ehrlich, DS., Itoh, K., Takagi, T., Sakaki, Y., Hayashi, T., Hattori, M
  • Journal Title: Anaerobe 13 Pages: 220-227
  • NAID: 120007121875
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Inhibitory effects of fermented brown rice on induction of acute colitis by dextran sulfate sodium in rats (2007)
  • Author(s): Kataoka, K., Ogasa, S., Kuwahara, T., Bando, Y., Hagiwara, M., Arimochi, H., Nakanishi, S., Iwasaki, T., Ohnishi, Y
  • Journal Title: Dig. Dis. Sci (in press)
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Vibrionaceae versatile bacterial family with evolutionary conserved variability (2007)
  • Author(s): Dryselius, R., Kurokawa, K., Iida, T.
  • Journal Title: Res. Microbiol 158 Pages: 479-486
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] The entire organization of transcription unites on the Bacillus subtilis genome (2007)
  • Author(s): Kobayashi, H., Akitomi, J., Fujii, N., Kobayashi, K, Amin, M.A., Kurokawa, K., Ogasawara, N., Kanaya, S
  • Journal Title: BMC Genomics 8 Pages: 197-201
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Analysis of invariant sequences in 266 complete genomes (2007)
  • Author(s): Goto, N., Kurokawa, K., Yasunaga, T
  • Journal Title: Gene 401 Pages: 172-180
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Genomic vievv on the evolution of enterohemorrhagic Escherichia coli (2007)
  • Author(s): Hayashi, T., Ooka, T., Ogura, Y., Asadulghani
  • Journal Title: Evolutionary Biology of Bacterialand Fungal Pathogens Pages: 407-419
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] TccP2 of O157: H7 and non-O157 enterohemorrhagic Escherichia coli (EHEC): challenging the dogma of EHEC-induced actin olymerization (2007)
  • Author(s): Ogura Y., et. al.
  • Journal Title: Infect. Immun 75(2) Pages: 604-612
  • Peer Reviewed
• [Journal Article] Characterization of tccP2 carried by atypical enteropathogenic Escherichia coli. (2007)
  • Author(s): Ooka T., et. al.
  • Journal Title: FEMS Microbiol. Lett 271 Pages: 126-135
  • Peer Reviewed
• [Journal Article] TbcP2-mediated subversion of actin dynamics by EPEC 2-a distinct evolutionary lineage of enteropathogenic Escherichia coli (2007)
  • Author(s): Whale A., et. al.
  • Journal Title: Microbiology 153 Pages: 1743-1755
  • Peer Reviewed
• [Journal Article] Distribution of stable DnaA-bindingd sites on the Bacillus Subtilis genome detected using a modified ChIP-chip method. (2007)
  • Author(s): Ishikawa S., et. al.
  • Journal Title: DNA Res. 14 Pages: 155-168
  • Peer Reviewed
• [Journal Article] Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes. (2007)
  • Author(s): Kurokawa K., et. al.
  • Journal Title: DNA Res. 14 Pages: 169-181
  • Peer Reviewed
• [Journal Article] Modifying effects of fermented brown rice on fecal microbiota in rats (2007)
  • Author(s): Kataoka K., et. al.
  • Journal Title: Anaerobe 13 Pages: 220-227
  • Peer Reviewed
• [Journal Article] Vibrionaceae; versatile bacterial family with evolutionary conserved variability. (2007)
  • Author(s): Dryselius, R., et. al.
  • Journal Title: Res. Microbiol. 158 Pages: 479-486
  • Peer Reviewed
• [Journal Article] The entire organization of transcription unites on the Bacillus subtilisgenome. (2007)
  • Author(s): Kobayashi, H., et. al.
  • Journal Title: BMC Genomics 8 Pages: 197-201
  • Peer Reviewed
• [Journal Article] Analysis of invariant sequences in 266 complete genomes. (2007)
  • Author(s): Goto, N., et. al.
  • Journal Title: Gene, 401 Pages: 172-180
  • Peer Reviewed
• [Journal Article] 微生物における比較ゲノム研究の進展 (2007)
  • Author(s): 林哲也
  • Journal Title: 実験医学 25(2) Pages: 266-272
• [Journal Article] ヒト腸内細菌叢のゲノムシークエンス (2007)
  • Author(s): 服部正平、他
  • Journal Title: 腸内細菌学雑誌 21(3) Pages: 187-197
• [Journal Article] メタゲノミクスのバイオインフォマティクス (2007)
  • Author(s): 黒川顕
  • Journal Title: 化学と生物 45 Pages: 495-501
• [Journal Article] RNA polymerase b-subunit gene (rpoB) sequence analysis for the identification of Bacteroides spp (2007)
  • Author(s): K.S.Ko, et al.
  • Journal Title: Clin. Microbiol. Infect. 13 Pages: 48-54
• [Journal Article] TccP2 of O157 : H7 and non-O157 enterohemorrhagic Escherichia coli (EHEC) : challenging the dogma of EHEC-induced actin polymerization. (2007)
  • Author(s): Y.Ogura, et al.
  • Journal Title: Infect. Immun. 75(2) Pages: 604-612
• [Journal Article] Breaking the barrier between commensalism and pathogenicity (2006)
  • Author(s): Hayashi T.
  • Journal Title: Science 313 Pages: 772-773
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] An extensive repertoire of type III secretion effectors in Escherichia coli o157 and the role of lambdoid phages in their dissemination (2006)
  • Author(s): Tobe T., et. al.
  • Journal Title: Proc.Natl.Acad.Sci.USA. 103 Pages: 14941-14946
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] ppGpp with DksA controls gene expression in the LEE pathogenicity island of enterohaemorrhagic Escherichia coli through activation of two virulence regulatory genes (2006)
  • Author(s): Nakanishi N., et. al.
  • Journal Title: Mol.Microbiol. 61(1) Pages: 194-205
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Complexity of the genomic diversity of enterohaemorrhagic Escherichia coli o157 revealed by the combinational use of the o157 Sakai oligo DNA microarray and the Whole Genome PCR Scanning (2006)
  • Author(s): Ogura Y., et. al.
  • Journal Title: DNA Res. 13 Pages: 3-14
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Suppressive effect of Clostridium perfringens-produced heat-stable substance(s)on proliferation of human colon adenocarcinoma HT29 cells in culture (2006)
  • Author(s): Arimochi H., et. al.
  • Journal Title: Cancer Letter 75(2) Pages: 228-234
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Prediction of protein functions based on protein-protein interaction networks: A min-cut approach (2006)
  • Author(s): Altaf-Ul-Amin, et. al.
  • Journal Title: BMC Bioinfo. 7 Pages: 207-220
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Sperical SOM and arrangement of neurons using herix on sphere (2006)
  • Author(s): Nishio H., et. al.
  • Journal Title: IPSJ Transactions on Mathematical Modeling and Its Applications 47 Pages: 56-60
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in Mycobacteria (2006)
  • Author(s): Morita Y., et. al.
  • Journal Title: J.Biol.Chem. 281 Pages: 25143-25155
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Bioinformatics tool for genomic era; A step towards the in silico experiments-focused on molecular cloning (2006)
  • Author(s): Ohyama A., et. al.
  • Journal Title: J.Comp.Aid.Chem. 102-115 Pages: 102-115
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Elucidating conservation of genes in multiple genomes based on graphs configured by bidirectional best-hit relationships (2006)
  • Author(s): Maeno H., et. al.
  • Journal Title: Trans.Bioinformat. 47 Pages: 1-11
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Comparison of protein complexes predicted from PPI networks by DPClus and Newman clustering algorithms (2006)
  • Author(s): Tuji H., et. al.
  • Journal Title: Trans.Bioinformat. 47 Pages: 31-41
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Escherichia coli histone-like protein H-NS preferentially binds to horizontally acquired DNA in association with RNA polymerase (2006)
  • Author(s): Oshima T., et. al.
  • Journal Title: DNA Res. 13 Pages: 141-153
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] DPCIus:A density-periphery based graph clustering software mainly focused on detection of protein complexes in interaction networks.Polymerization (2006)
  • Author(s): Altaf-Ul-Amin, et. al.
  • Journal Title: J.Comp.Aid.Chem. 7 Pages: 150-156
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] ヒト常在菌を含む環境細菌叢のメタゲノム解析 (2006)
  • Author(s): 林哲也, 服部正平
  • Journal Title: 細胞工学 25(7) Pages: 812-816
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Complexity of the genomic diversity of enterohaemorrhagic Escherichia coli O157 revealed by the combinational use of the O157 Sakai oligo DNA microarray and the Whole Genome PCR Scanning (2006)
  • Author(s): Ogura, Y., Kurokawa, K., Ooka, T., Tashiro, K., Tobe, T., Ohnishi, M., Nakayama, K., Morimoto, T., Terajima, J., Watanabe, H., Kuhara, S., Hayashi, T
  • Journal Title: DNA Res 13 Pages: 3-14
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] ppGpp with DksA controls gene expression in the LEE pathogenicity island of enterohaemorrhagic Escherichia coli through activation of two virulence regulatory genes (2006)
  • Author(s): Nakanishi, N., Abe, H., Ogura, Y., Hayashi, T., Tashiro, K., Kuhara, S., Sugimoto, N., Tobe, T
  • Journal Title: Mol. Microbiol 61(1) Pages: 194-205
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] An extensive repertoire of type III secretion effectors in Escherichia coli 0157 and the role of lambdoid phages in their dissemination (2006)
  • Author(s): Tobe, T., Beatson, S. A., Taniguchi, H., Abe, H., Bailey, C. M, Fivian, A., Younis, R., Matthews, S., Marches, O., Frankel, G., Hayashi, T., Pallen, M. J
  • Journal Title: Proc. Natl. Acad. Sci. USA 103 Pages: 14941-14946
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Breaking the barrier between commensalism and pathogeni city (2006)
  • Author(s): Hayashi, T
  • Journal Title: Science 313 Pages: 772-773
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Suppressive effect of Clostridium perfringens-produced heat-stable substance(s) on proliferation of human colon adenocarcinoma HT29 cells in culture (2006)
  • Author(s): Arimochi, H., Morita, K., Kataoka, K., Nakanishi, S., Kuwahara, T., Ohnishi, Y
  • Journal Title: Cancer Letter 241 Pages: 228-34
  • NAID: 10019924742
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Prediction of protein functions based on protein-protein interaction networks : A min-cut approach (2006)
  • Author(s): Altaf-Ul-Amin, M., Koma, T., Kurokawa, K., Kanaya, S
  • Journal Title: BMC Bioinfo 7 Pages: 207-220
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Sperical SOM and arrangement of neurons using herix on sphere (2006)
  • Author(s): Nishio, H., Altaf-Ul-Amin, M., Kurokawa, K., Kanaya, S
  • Journal Title: IPSJ Transactions on Mathematical Modeling and Its Applications 47, 14 Pages: 56-60
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in Mycobacteria (2006)
  • Author(s): Morita, Y., Sena, C., Waller, R., Kurokawa, K., Semee, M., Nakatani, F., Haites, R., Billman-Jacobe, H., McConville, M., Maeda, Y., Kinoshita, T
  • Journal Title: J. Biol. Chem. 281 Pages: 25143-25155
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Bioinformatics tool for genomic era ; A step towards the in silico experiments - focused on molecular cloning (2006)
  • Author(s): Ohyama, A., Kurokawa, K., Enai, K., Saitoh, H., Kanaya, S., Altaf-Ul-Amin, M., Ogasawara, N
  • Journal Title: J. Comp. Aid. Chem 7 Pages: 102-115
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Elucidating conservation of genes in multiple genomes based on graphs con figured by bidirectional best-hit relationships (2006)
  • Author(s): Maeno, H., Altaf-Ul-Amin, M., Shinbo, Y., Kurokawa, K., Ogasawara, N., Kanaya, S
  • Journal Title: Trans. Bioinformat 47 Pages: 1-11
  • NAID: 110004862622
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Comparison of protein complexes predicted from PPI networks by DPClus and Newman clustering algorithms (2006)
  • Author(s): Tuji, H., Altaf-Ul-Amin, M., Arita, M., Nishio, H., Shinbo, Y., Kurokawa, K., Kanaya, S
  • Journal Title: Trans. Bioinformat 47 Pages: 31-41
  • NAID: 110004862625
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Escherichia coli histone-like protein H-NS preferentially binds to horizontally acquired DNA in association with RNA polymerase (2006)
  • Author(s): Oshima, T., Ishikawa, S., Kurokawa, K., Aiba, H., Ogasawara, N
  • Journal Title: J. Comp. Aid. Chem 7 Pages: 150-156
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] DPClus : A density-periphery based graph clustering software mainly focused on detection of protein complexes in interaction networks (2006)
  • Author(s): Altaf-Ul-Amin, M., Tuji, H., Kurokawa, K., Asahi, H., Shnbo, Y., Kanaya, S
  • Journal Title: The Biology of Vibrios (ASM press)
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Modifying effects of fermented brown rice on fecal microbiota in rats (2006)
  • Author(s): Kataoka, K., Kibe, R., Kuwahara, T., Hagiwara, M., Arimochi, H., Iwasaki, T., Benno, Y., Ohnishi, Y
  • Journal Title: DNARes 13 Pages: 141-153
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Breaking the barrier between commensalism and pathogenicity. (2006)
  • Author(s): T.Hayashi.
  • Journal Title: Science 313 Pages: 772-773
• [Journal Article] An extensive repertoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their dessemination. (2006)
  • Author(s): T.Tobe, et al.
  • Journal Title: Proc. Natl. Acad. Sci. USA. 103 Pages: 14941-14946
• [Journal Article] ppGpp with DksA controls gene expression in the LEE pathogenicity island of enterohaemorrhagic Escherichia coli through activation of two virulence regulatory genes. (2006)
  • Author(s): N.Nakanishi, et al.
  • Journal Title: Mol. Microbiol. 61(1) Pages: 194-205
• [Journal Article] Complexity of the genomic diversity of enterohaemorrhagic Escherichia coli O157 revealed by the combinational use of the O157 Sakai oligo DNA microarray and the Whole Genome PCR Scanning. (2006)
  • Author(s): Y.Ogura, et al.
  • Journal Title: DNA Res. 13 Pages: 3-14
• [Journal Article] Suppressive effect of Clostridium perfringens-produced heat-stable substance(s) on proliferation of colon adenocarcinoma HT29 cells in culture. (2006)
  • Author(s): H.Arimochi, et al.
  • Journal Title: Cancer Letter 75(2) Pages: 228-234
• [Journal Article] Prediction of protein functions based on protein-protein interaction networks : A min-cut approach. (2006)
  • Author(s): Altaf-Ul-Amin, et al.
  • Journal Title: BMC Bioinfo. 7 Pages: 207-220
• [Journal Article] Sperical SOM and arrangement of neurons using herix on sphere.. (2006)
  • Author(s): H.Nishio, st al.
  • Journal Title: IPSJ Transactions on Mathematical Modeling and Ist Applications. 47 Pages: 56-60
• [Journal Article] PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in Mycobacteria. (2006)
  • Author(s): Y.Morita, et al.
  • Journal Title: J. Biol. Chem. 281 Pages: 25143-25155
• [Journal Article] Bioinfomatics tool for genomic era; A step towards the in silico experiments - focused on molecular cloning. (2006)
  • Author(s): A.Ohyama, et al.
  • Journal Title: J. Comp. Aid. Che. 7 Pages: 102-115
• [Journal Article] Elucidating conservation of genes in multiple genomes based on graphs configured by bidirectional best-hit relationships. (2006)
  • Author(s): H.Maeno, et al.
  • Journal Title: Trans. Bioinformat. 47 Pages: 1-11
• [Journal Article] Comparison of protein complexes predicted from PPI networks by DPClus and Newman clustering algorithms. (2006)
  • Author(s): H.Tuji, et al.
  • Journal Title: Trans. Bioinformat. 47 Pages: 31-41
• [Journal Article] Escherichia coli histone-like protein H-NS preferentially binds to horizontally acquired DNA in association with RNA polymerase. (2006)
  • Author(s): T.Oshima, et al.
  • Journal Title: DNA Res. 13 Pages: 141-153
• [Journal Article] DPClus : A density-periphery based graph clustering software mainly focused on detection of protein complexes in interaction networks. (2006)
  • Author(s): Altaf-Ul-Amin, et al.
  • Journal Title: J. Comp. Aid. Chem. 7 Pages: 150-156
• [Journal Article] ヒト常在菌を含む環境細菌叢のメタゲノム解析. (2006)
  • Author(s): 林哲也, 服部正平
  • Journal Title: 細胞工学 25(7) Pages: 812-816
• [Journal Article] Inhibitory effects of fermented brown rice on induction of acute colitis by dextran sulfate sodium in rats
  • Author(s): Kataoka, K., et. al.
  • Journal Title: Dig.Dis.Sci.
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Inhibitory effects of fermented brown rice on induction of acute colitis by dextran sulfate sodium in rats.
  • Author(s): Kataoka K., et. al.
  • Journal Title: Dig. Dis. Sci. (in press)
  • Peer Reviewed
• [Journal Article] Characterization of tccP2 carried by atypical enteropathogenic Escherichia coli.
  • Author(s): T.Ooka, et al.
  • Journal Title: FEMS Microbiol. Lett. (in press)
• [Journal Article] TccP2-mediated subversion of actin dynamics by EPEC2-a distinct evolutionary lineage of enteropathogenic Escherichia coli.
  • Author(s): A.Whale, et al.
  • Journal Title: Microbiology (in press)
• [Journal Article] An improved DNA isolation method for metagenomic analysis of the microbial flora of the human intestine.
  • Author(s): M.Hidetoshi, et al.
  • Journal Title: Microbes and Environments (in press)
• [Presentation] Comparative genomics of O157 and non-O157 enterohemorrhagic Escherichia coli (2008)
  • Author(s): Hayashi T.
  • Organizer: Invited Seminar(The Wellcome Trust Sanger Institute)
  • Place of Presentation: Cambridge,UK
  • Year and Date: 2008-03-17
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Comparative genomics of O157 and non-O157 enterohemorrhagic Escherichia coli. (2008)
  • Author(s): Hayashi T.
  • Organizer: Invited Seminar (The Wellcome Trust Sanger Institute)
  • Place of Presentation: Cambridge, UK
  • Year and Date: 2008-03-17
• [Presentation] Comparative genomics of O157 and non-O157 enterohemorrhagic Escherichia coli (2008)
  • Author(s): Hayashi T.(Invited Speaker)
  • Organizer: The 24th RIB International Symposium on The Frontier of Microbiology -Resouces, Environment, and Genome
  • Place of Presentation: Okayama
  • Year and Date: 2008-01-25
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Comparative genomics of O157 and non-O157 enterohemorrhagic Escherichia coli (2008)
  • Author(s): Hayashi T. (Invited Speaker)
  • Organizer: The 24th RIB International Symposium on The Frontier of Microbiology-Resouces, Environment, and Genome-
  • Place of Presentation: Okayama
  • Year and Date: 2008-01-25
• [Presentation] 腸管出血性大腸菌(O26,O111,O103)の全ゲノム解析 (2008)
  • Author(s): 小椋 義俊, その他
  • Organizer: 第2回日本ゲノム微生物学会年会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] オリエンチア・ツツガムシ株間における比較ゲノム解析 (2008)
  • Author(s): 中山 恵介, その他
  • Organizer: 第2回日本ゲノム微生物学会年会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 大腸菌における0抗原をコードする領域の組換え過程の解析 (2008)
  • Author(s): 井口 純, その他
  • Organizer: 第2回日本ゲノム微生物学会年会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 腸営団血性大腸菌Ol57の小規模ゲノム構造多型の形成機i構に関する詳細な解析 (2008)
  • Author(s): 大岡 唯祐, その他
  • Organizer: 第2回日本ゲノム微生物学会年会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] A genome-wide survey on phage induction and propagation revealed defective prophages spread virulence determinants from Sakai prophage pool (2008)
  • Author(s): Asadulghani, et. al.
  • Organizer: 第2回日本ゲノム微生物学会年会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 腸管出血性大腸菌の病原性制御因子による遺伝子発現制御機構 (2008)
  • Author(s): 戸辺 亨, その他
  • Organizer: 第2回日本ゲノム微生物学会年会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Porphyromonas gingivalis のtransposable elementsの解析 (2008)
  • Author(s): 内藤 真理子, その他
  • Organizer: 第2回日本ゲノム微生物学会年会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ヒト腸内常在大腸菌のゲノム解析 (2008)
  • Author(s): 藤 英博, その他
  • Organizer: 第2回日本ゲノム微生物学会年会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ヒト腸内細菌叢のメタゲノム解析 (2008)
  • Author(s): 林 哲也(シンポジスト)
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 腸管出血性大腸菌の進化におけるファージの役割 (2008)
  • Author(s): 小椋 義俊(シンポジスト)
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] オリエンチア・ツツガムシ株間における比較ゲノム解析 (2008)
  • Author(s): 中山 恵介, その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ウシの趾乳頭腫症病変組織から分離されたTreponema phagedenis近縁種の分子系統解析 (2008)
  • Author(s): 山崎 和子, その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] EPEC O55:H7株の溶血活性 (2008)
  • Author(s): 村瀬 一典, その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 大腸菌における0抗原をコードする領域の組換え過程 (2008)
  • Author(s): 井口 純, その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 腸管出血性大腸菌O157の小規模ゲノム構造多型に関する詳細な解析 (2008)
  • Author(s): 大岡 唯祐, その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Lateral transfer of virulence or related genes by defective prophages of Sakai prophage pool (2008)
  • Author(s): Asadulghani, et. al.
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] OspEファミリータンパク質による感染宿主細胞のRhoAシグナル伝達系の制御 (2008)
  • Author(s): 三浦 雅史, その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] C型とD型ボツリヌスC2毒素遺伝子をコードするプラスミドの解析 (2008)
  • Author(s): 阪口 義彦, その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 腸管出血性大腸菌の病原性発現調節における核様体構造の役割 (2008)
  • Author(s): 戸辺 亨, その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ウシ趾乳頭腫症病変部より分離されたトレポネーマ分離株の性状および遺伝子型について (2008)
  • Author(s): 矢野 貴久, その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Bacteroides fragilisのSusC/D shuMonにおける多重逆位を制御する部位特異的組換え酵素の同定 (2008)
  • Author(s): 今大路 治之, その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 発酵玄米の摂取が腸内菌叢及び腸内環境におよぼす影響 (2008)
  • Author(s): 井形 和枝, その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 腸管病原性ウェルシュ菌の遺伝学的特徴 (2008)
  • Author(s): 出口 安芸, その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Comparative genomics of O157 and non-O157 enterohemorrhagic Escherichia coli. (2008)
  • Author(s): Hayashi, T
  • Organizer: The 24th RIB International Symposium on The Frontier of Microbiology -Resouces, Environment, and Genome-
  • Place of Presentation: Okayama(Invited Speaker)
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Comparative genomics of O157 and non-O157 enterohemorrhagic Escherichia coli (2008)
  • Author(s): Hayashi, T
  • Organizer: Invited Seminar(The Wellcome Trust Sanger Institute)
  • Place of Presentation: Cambridge, UK
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 大腸菌におけるO抗原をコードする領域の組換え過程の解析 (2008)
  • Author(s): 井口純、その他
  • Organizer: 第2回日本ゲノム微生物学会年会
  • Place of Presentation: 大阪
• [Presentation] 腸管出血性大腸菌O157の小規模ゲノム構造多型の形成機構に関する詳細な解析 (2008)
  • Author(s): 大岡唯祐, その他
  • Organizer: 第2回日本ゲノム微生物学会年会
  • Place of Presentation: 大阪
• [Presentation] A genome-wide survey on phage induction and propagation revealed defective prophages spread virulence determinants from Sakaiprophage pool. (2008)
  • Author(s): Asadulghani, et. al.
  • Organizer: 第2回日本ゲノム微生物学会年会
  • Place of Presentation: 大阪
• [Presentation] 大腸菌におけるO抗原をコードする領域の組換え過程 (2008)
  • Author(s): 井口純, その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
• [Presentation] Bacteroides fragilisのsus C/D shufflonにおける多重逆位を制御する部位特異的組換え酵素の同定 (2008)
  • Author(s): 今大路治之、その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
• [Presentation] 発酵玄米の摂取が腸内菌叢及び腸内環境におよぼす影響. (2008)
  • Author(s): 井形和枝、その他
  • Organizer: 第81回日本細菌学会総会
  • Place of Presentation: 京都
• [Presentation] メタゲノムインフォマティクス (2007)
  • Author(s): 黒川 顕
  • Organizer: 第2回放射線防御研究センターシンポジウム
  • Place of Presentation: 千葉
  • Year and Date: 2007-12-18
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes (2007)
  • Author(s): Kuwahara, T., et. al.
  • Organizer: The 7th International Workshop on Advanced Genomics
  • Place of Presentation: Tokyo
  • Year and Date: 2007-11-27
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ヒト腸内フローラのメタゲノム解析 (2007)
  • Author(s): 黒川 顕
  • Organizer: 新化学発展協会
  • Place of Presentation: 東京
  • Year and Date: 2007-10-23
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 病原性大腸菌O157-ゲノム解析から見た病原細菌の多様性と適応戦略 (2007)
  • Author(s): 林 哲也(シンポジスト)
  • Organizer: 日本生物科学研究所創立60周年記念シンポジウム「新興・再興するヒトと動物の共通感染症-その現状と対策を探る」
  • Place of Presentation: 東京
  • Year and Date: 2007-10-02
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 病原性大腸菌Ol57-ゲノム解析から見た病原細菌の多様性と適応戦略 (2007)
  • Author(s): 林哲也(シンポジスト)
  • Organizer: 日本生物科学研究所 創立60周年記念シンポジウム「新興・再興するヒトと動物の共通感染症-その現状と対策を探る」
  • Place of Presentation: 東京
  • Year and Date: 2007-10-02
• [Presentation] ヒト腸内フローラのメタゲノム解析 (2007)
  • Author(s): 黒川 顕
  • Organizer: 日本乳酸菌学会
  • Place of Presentation: 相模原
  • Year and Date: 2007-07-05
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Metagenomics of microbial community in human intestine (2007)
  • Author(s): Kurokawa, K., et. al.
  • Organizer: The Biology of Genomes
  • Place of Presentation: Cold Spring Harbor Laboratory,NY,U.S.A
  • Year and Date: 2007-05-07
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Metagenomics of microbial community in human intestine (2007)
  • Author(s): Kurokawa, K., et. al.
  • Organizer: The Biology of Genomes
  • Place of Presentation: Cold Spring Harbor Laboratory, NY, U.S.A
  • Year and Date: 2007-05-07
• [Presentation] ゲノム解析からメタゲノム解析へ (2007)
  • Author(s): 黒川 顕
  • Organizer: 第3回アグリバイオインフォマティクスシンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2007-03-19
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Phage induction and inter-prophage interaction in the prophage pool of an enterohemorrhagic Escherichia coli O157:H7 genome (2007)
  • Author(s): Asadulghani, et. al.
  • Organizer: 第1回日本ゲノム微生物学会年会
  • Place of Presentation: 木更津
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 腸管出血性大腸菌ゲノムの比較解析 (2007)
  • Author(s): 小椋 義俊, その他
  • Organizer: 第1回日本ゲノム微生物学会年会
  • Place of Presentation: 木更津
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 多系統大腸菌に分布する055抗原合成オペロンの解析 (2007)
  • Author(s): 井口 純、その他
  • Organizer: 第1回日本ゲノム微生物学会年会
  • Place of Presentation: 木更津
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ウシの趾乳頭腫症(PDD)起因菌の解析 (2007)
  • Author(s): 山崎 和子, その他
  • Organizer: 第1回日本ゲノム微生物学会年会
  • Place of Presentation: 木更津
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 病原性大腸菌におけるRTX様蛋白質の比較解析 (2007)
  • Author(s): 村瀬 一典, その他
  • Organizer: 第1回日本ゲノム微生物学会年会
  • Place of Presentation: 木更津
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 病原性大腸菌における外来性因子による遺伝子発現制御 (2007)
  • Author(s): 戸辺 亨, その他
  • Organizer: 第1回日本ゲノム微生物学会年会
  • Place of Presentation: 木更津
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ヒト腸内細菌叢のメタゲノム解析 (2007)
  • Author(s): 服部 正平, その他
  • Organizer: 第1回日本ゲノム微生物学会年会
  • Place of Presentation: 木更津
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 草菌ゲノム上でのDnaA結合部位の分布 (2007)
  • Author(s): 石川 周, その他
  • Organizer: 第1回日本ゲノム微生物学会年会
  • Place of Presentation: 木更津
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ヒト腸内常在大腸菌のゲノム解析 (2007)
  • Author(s): 大島 健志朗, その他
  • Organizer: 第1回日本ゲノム微生物学会年会
  • Place of Presentation: 木更津
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Porphyromonas gingivalis ATCC33277株の全ゲノム塩基配列決定 (2007)
  • Author(s): 内藤 真理子, その他
  • Organizer: 第1回日本ゲノム微生物学会年会
  • Place of Presentation: 木更津
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ゲノム解析データから見た大腸菌の多様性と菌種内進化 (2007)
  • Author(s): 林 哲也(ワークショップ)
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 腸管出血性大腸菌O157:H7のHI型分泌蛋白質NIeHによる免疫応答制御 (2007)
  • Author(s): 安倍 裕順, その他(ワークショップ)
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 腸管出血性大腸菌の病原性転写調節因子LerおよびPchによる発現制御ネットワークの構築 (2007)
  • Author(s): 戸辺 亨, その他(ワークショップ)
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Porphyromonas gingivalis ATCC33277株の全ゲノム塩基配列決定 (2007)
  • Author(s): 内藤 真理子, その他
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 感染宿主細胞の形態維持に関与する病原性因子の機能解析 (2007)
  • Author(s): 三浦 雅史, その他
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 大腸菌O55抗原合成オペロンの水平伝播について (2007)
  • Author(s): 井口 純, その他
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] non-O157EHECゲノムにおけるIS分布の解析 (2007)
  • Author(s): 大岡 唯祐, その他
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Phage induction and prophage-prophage interaction in the prophage-po of of O157 Sakai genome (2007)
  • Author(s): Asadulghani, et. al.
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] EHEC O157とnon-O157 EHEC(O26,O111,O103)の比較ゲノム解析 (2007)
  • Author(s): 小椋 義俊, その他
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 病原性大腸菌におけるRTX様蛋白質の解析 (2007)
  • Author(s): 村瀬 一典, その他
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 宿主細胞の違いによるオリエンチア・ツツガムシの遺伝子発現パターンの変化 (2007)
  • Author(s): 中山 恵介, その他
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] C型とD型ボツリヌスC2毒素遺伝子をコードするプラスミドの解析 (2007)
  • Author(s): 阪口 義彦, その他
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ウシの趾乳頭腫症(PDD)起因菌の解析 (2007)
  • Author(s): 山崎 和子, その他
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大坂
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 免疫磁気ビーズ法による牛趾乳頭腫症病変部からのTrePOIIemama菌の検出 (2007)
  • Author(s): Kyaw Kyaw Moe、その他
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Baclerofdes fragilisのDNA逆位による外膜vesicle形成の制御 (2007)
  • Author(s): 今大路 治之, その他
  • Organizer: 第80回日本細菌学会総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Genomics of different enterohaemorrhagic E.coli serotypes (2007)
  • Author(s): Hayashi, T.(Invited Speaker)
  • Organizer: Genomics for Animal Health(E. coli and Salmonella workshop)
  • Place of Presentation: Utrecht
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 大腸菌におけるO抗原合成遺伝子群を含む水平伝播領域の解析-O5からO157への入れ替わりと055の伝播について (2007)
  • Author(s): 井口 純, 他
  • Organizer: 第11回腸管出血性大腸院感染症シンポジウム
  • Place of Presentation: 安曇野
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 病原性大腸菌におけるRTXの保有状況および溶血毒素としての可能性 (2007)
  • Author(s): 村瀬 一典, 他
  • Organizer: 第60回日本細菌学会九州支部総会
  • Place of Presentation: 長崎
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 眼結膜由来のコリネバクテリウムにおけるフルオロキノロン耐性 (2007)
  • Author(s): 桑原 知巳, 他
  • Organizer: 第60回日本細菌学会中国・四国支部総会
  • Place of Presentation: 岡山
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Bacteroides fragilisのsusC/D shufflonを制御するsite-specificrecombinaseの同定 (2007)
  • Author(s): 今大路 治之, 他
  • Organizer: 第60回日本細菌学会中国・四国支部総会
  • Place of Presentation: 岡山
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ゲノム解読による生物学の変貌〜病原細菌の場合 (2007)
  • Author(s): 林 哲也(招待講演)
  • Organizer: 第1回ぜん虫研究会
  • Place of Presentation: 宮崎
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Bacteroides fragilisにおける包括的作動性部位特異的組換え酵素による菌体表層構造の可変性 (2007)
  • Author(s): 今大路 治之, 他
  • Organizer: 第30回日本分子生物学会年会第80回日本生化学会大会合同大会
  • Place of Presentation: 横浜
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Metagenomics of microbial community in human intestine (2007)
  • Author(s): Kurokawa, K., Oshima, K., Toh, H., Toyoda, A., Itoh, T., Noguchi, H., Yamakura, K., Itoh, T., Kuwahara, H., Morita, H., Takami, T., Hayashi, G., Hattori, M
  • Organizer: The Biology of Genomes
  • Place of Presentation: Cold Spring Harbor Laboratory, NY, U.S.
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Genomics of different enterohaemorrhagic E.coli serotyp es (2007)
  • Author(s): Hayashi, T
  • Organizer: Genomics for Animal Health(E. coli and Salmonella workshop)
  • Place of Presentation: Utrecht(Invited Speaker)
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes (2007)
  • Author(s): Kuwahara, T., Kurokawa, K., Itoh, T., Oshima, K., Toh, H., Toyoda, A., Takami, H., Morita, H., Sharma, V. K., Srivastava, T.P., Taylor, T. D., Noguchi, H., Mori, H., Ogura, Y., Ehrlich, D. S., Itoh, K., Takagi, T., Sakaki, Y., Hayashi, T., Hattori, M
  • Organizer: The 7th International Workshop on Advanced Genomics
  • Place of Presentation: Tpkyo
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Genomics of different enterohaemorrhagic E. coli serotypes (2007)
  • Author(s): Hayashi, T. (Invited Speaker)
  • Organizer: Genomics for Animal Health (E. coli and Salmonella workshop)
  • Place of Presentation: Utrecht
• [Presentation] 大腸菌におけるO抗原合成遺伝子群を含む水平伝播領域の解析-O55からO157への入れ替わりとO55の伝播について. (2007)
  • Author(s): 井口純、他
  • Organizer: 第11回腸管出血性大腸院感染症シンポジウム
  • Place of Presentation: 安曇野
• [Presentation] Bacteroides fragilisのsus C/D shufflonを制御するsite-specific recombinaseの同定. (2007)
  • Author(s): 今大路治之、他
  • Organizer: 第60回日本細菌学会中国・四国支部総会
  • Place of Presentation: 岡山
• [Presentation] Bacteroides fragilisにおける包括的作動性部位特異的組換え酵素による菌体表層構造の可変性 (2007)
  • Author(s): 今大路治之、他
  • Organizer: 第30回日本分子生物学会年会第80回日本生化学会大会合同大会.
  • Place of Presentation: 横浜
• [Presentation] Genome analysis of O157 EHEC and non-O157 EHEC (2006)
  • Author(s): Hayashi T.
  • Organizer: A meeting of the working group on E.Coli in the frame of WP07(Functional Genome Analyses)of EADGENE.(Invited Speaker)
  • Place of Presentation: Paris
  • Year and Date: 2006-09-29
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Metagenomics of microbial community in human intestine (2006)
  • Author(s): Kurokawa K., et. al.
  • Organizer: The Biology of Genomes
  • Place of Presentation: Cold Spring Harbor Laboratory,NY,U.S
  • Year and Date: 2006-05-11
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Comparative genome analysis of O157 and non-O157 enterohemorrhagic Escherichia coli strains using the whole genome PCR scanning and the O157 oligoDNA microarray (2006)
  • Author(s): Ogura, Y., et. al.
  • Organizer: VTEC 2006 Melbourne(6th International Symposium on Shiga Toxin(Verocytotoxin)-Producing Escherichia coli Infections)
  • Place of Presentation: Melbourne
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] The mechanism of genomic diver E.coli O157:H7 (2006)
  • Author(s): Ooka T., et. al.
  • Organizer: VTEC 2006 Melbourne(6th International Symposium on Shiga Toxin(Verocytotoxin)-Producing Escherichia coli Infections)
  • Place of Presentation: Melbourne
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Comparative genome analysis of non-O157 enterohemorrhagic Escherichia coli strains (2006)
  • Author(s): Ogura, Y., et. al.
  • Organizer: The 41<st>Joint Conference US-Japan Cooperative Medical Science Program Cholera Panel
  • Place of Presentation: Gifu
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] EHECゲノムの比較解析と全ゲノム解読の進捗状況 (2006)
  • Author(s): 小椋 義俊(シンポジスト)
  • Organizer: 第10回腸管出血性大腸菌感染症シンポジウム
  • Place of Presentation: 東京
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 腸管出血性大腸菌0157のゲノム多様性獲得メカニズムの解析 (2006)
  • Author(s): 大岡 唯祐, 他
  • Organizer: 第10回腸管出血性大腸菌感染症シンポジウム
  • Place of Presentation: 東京
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] A genome-wide survey of prophage induction and evaluation of the potentially active nature of Sakai prophage genomes (2006)
  • Author(s): Asadulghani, et. al.
  • Organizer: 第59回日本細菌学会九州支部総会
  • Place of Presentation: 久留米
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ゲノム解析から見えてきたこと (2006)
  • Author(s): 林 哲也(シンポジスト)
  • Organizer: 第27回日本食品微生物学会学術総会
  • Place of Presentation: 大阪
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Bacteroides fragilisのDNA逆位による線毛様構造物の発現制御 (2006)
  • Author(s): 今大路 治之, 他
  • Organizer: 第59回日本細菌学会中国・四国支部総会
  • Place of Presentation: 宇部市
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] マイクロマニピュレーターを用いた難培養性細菌 (2006)
  • Author(s): 桑原 知巳, 他
  • Organizer: 第59回日本細菌学会中国・四国支部総会
  • Place of Presentation: 宇部市
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Bacteroides fragilisの外膜vesicle形成におけるDNA逆位の関与 (2006)
  • Author(s): 今大路 治之, 他
  • Organizer: 日本分子生物学会2006フォーラム「分子生物学の未来」
  • Place of Presentation: 名古屋
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] IS分布を利用したマルチプレックスPCRによる0157簡易迅速菌株識別システムの開発 (2006)
  • Author(s): 大岡 唯祐
  • Organizer: 平成18年度九州微生物研究会総会
  • Place of Presentation: 福岡
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Metagenomics of microbial community in human intestine (2006)
  • Author(s): Kurokawa, K., Oshima, K., Toh, H., Toyoda, A., Itoh, T., Noguchi, H., Yamakura, K., Itoh, K., Kuwahara, T., Morita, H., Takami, H.,Hayashi', T., Hattori., T
  • Organizer: The Biology of Genomes
  • Place of Presentation: Cold Spring Harbor Laboratory, NY,U.S.
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Genome analysis of O157 EHEC and non-O157 EHEC (2006)
  • Author(s): Hayashi., T
  • Organizer: A meeting of the working group on E. Coli in the frame of WP07(Functional Genome Analyses) of EADGENE
  • Place of Presentation: Paris(Invited Speaker)
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Comparative genome analysis of O157 and non-O157 enterohemorrhagic Escherichia coli strains using the whole genome PCR scanning and the O157 oligoDNA microarray (2006)
  • Author(s): Ogura, Y., Ooka, K., Kurokawa, K., Terajima, J., Nakayama, K., Watanabe, H., Tobe, T., Hayashi., T
  • Organizer: VTEC 2006 Melbourne(6th International Symposium on Shiga Toxin(Verocyt otoxin)-Producing Escherichia coli Infections)
  • Place of Presentation: Melbourne
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] The mechanism of genomic diversification in Enterohemorrhagic E. coli O157 : H7 (2006)
  • Author(s): Ooka, T, Ogura, Y., Nakayama, K., Kurokawa, K., Ohnishi, M., Terajima, J., Watanabe, H., Hayashi., T
  • Organizer: VTEC 2006 Melbourne(6th International Symposium on Shiga Toxin(Verocyt otoxin) -Producing Escherichia coli Infections)
  • Place of Presentation: October, Melbourne.
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Comparative genome analysis of non-O157 enterohemorrhagic Escherichia coli strains (2006)
  • Author(s): Ogura, Y., Ooka., T Asadulghani, Iguchi, A., Nakayama, K., Hayashi., T
  • Organizer: The 41st Joint Conference US-Japan C oop erative Medical Science Program Cholera Panel
  • Place of Presentation: Gifu.
  • Description: 「研究成果報告書概要(欧文)」より
• [Book] 実験医学4月増刊号「バイオインフォマティクスツールの開発と生命研究への応用の最前線」 (2008)
  • Author(s): 黒川顕、服部正平
  • Total Pages: 226
  • Publisher: 羊土社,東京
• [Book] Evolutionary Biology of Bacterial and Fungal Pathogens (2007)
  • Author(s): Hayashi T., et. al.
  • Total Pages: 622
  • Publisher: ASM Press.Washington,D.C.
  • Description: 「研究成果報告書概要(和文)」より
• [Book] 細胞工学別冊「比較ゲノム学から読み解く生命システム」 (2007)
  • Author(s): 内山 郁夫, 林 哲也
  • Publisher: 秀潤社,東京
  • Description: 「研究成果報告書概要(和文)」より
• [Book] 細胞工学別冊「比較ゲノム学から読み解く生命システム」 (2007)
  • Author(s): 黒川 顕, 服部 正平
  • Publisher: 秀潤社,東京
  • Description: 「研究成果報告書概要(和文)」より
• [Book] 薬学領域の病原微生物学・感染症学・化学療法学 (2007)
  • Author(s): 林 哲也
  • Total Pages: 575
  • Publisher: 広川書店
  • Description: 「研究成果報告書概要(和文)」より
• [Book] バイオデータベースとウェブツールの手とり足とり活用法(改訂第2版) (2007)
  • Author(s): 黒川 顕
  • Publisher: 羊土社
  • Description: 「研究成果報告書概要(和文)」より
• [Book] 実験医学4月増刊号「バイオインフォマティクスツールの開発と生命研究への応用の最前線」 (2007)
  • Author(s): 黒川 顕, 服部 正平
  • Publisher: 羊土社,東京
  • Description: 「研究成果報告書概要(和文)」より
• [Book] Evolutionary Biology of Bacterial and Fungal Pathogens (2007)
  • Author(s): Hayashi T., et. al.
  • Total Pages: 622
  • Publisher: ASM Press. Washington, D.C.
• [Book] 細胞工学 別冊「比較ゲノム学から読み解く生命システム」 (2007)
  • Author(s): 内山郁夫、林哲也
  • Total Pages: 196
  • Publisher: 秀潤社,東京
• [Book] 細胞工学 別冊「比較ゲノム学から読み解く生命システム」 (2007)
  • Author(s): 黒川顕、服部正平
  • Total Pages: 196
  • Publisher: 秀潤社,東京
• [Book] 薬学領域の病原微生物学・感染症学・化学療法学 (2007)
  • Author(s): 林哲也
  • Total Pages: 575
  • Publisher: 廣川書店
• [Book] バイオデータベースとウェブツールの手とり足とり活用法(改訂第2版) (2007)
  • Author(s): 黒川顕
  • Total Pages: 254
  • Publisher: 羊土社
• [Book] The Biology of Vibrios (2006)
  • Author(s): T. Iida, K. Kurokawa
  • Publisher: ASM Press.Washington,D.C.
  • Description: 「研究成果報告書概要(和文)」より
• [Book] The Biology of Vibrios. (ASM Press) (2006)
  • Author(s): T.Iida, K.Kurokawa
  • Publisher: Comparative genomics : the genome configuration and the driving forces in the evolution of vibrios.
• [Patent(Industrial Property Rights)] 微生物の識別方法、及び該方法に使用するプライマー並びに識別キット (2006)
  • Inventor(s): 大岡 唯祐, 林 哲也, 小椋 義俊, 中山 恵介, 黒川 顕, 寺嶋 淳, 渡辺 治雄
  • Industrial Property Rights Holder: 大岡 唯祐, 林 哲也
  • Industrial Property Number: 2006-155279
  • Filing Date: 2006-06-02
  • Description: 「研究成果報告書概要(和文)」より
• [Patent(Industrial Property Rights)] 微生物の識別方法、及び該方法に使用するプライマー並びに識別キット (2006)
  • Inventor(s): 大岡 唯祐, 林 哲也, 小椋 義俊, 中山 恵介, 黒川 顕, 寺嶋 淳, 渡辺 治雄
  • Industrial Property Rights Holder: 大岡 唯祐, 林 哲也
  • Industrial Property Number: 2006-155279
  • Acquisition Date: 2006-06-13
  • Description: 「研究成果報告書概要(和文)」より
• [Patent(Industrial Property Rights)] 微生物の識別方法、及び該方法に使用するプライマー並びに識別キット (2006)
  • Inventor(s): 大岡唯祐, 林哲也, 小椋義俊, 中山恵介, 黒川顕, 寺嶋淳, 渡邊治雄
  • Industrial Property Rights Holder: 大岡唯祐, 林哲也
  • Industrial Property Number: 2006-155279
  • Filing Date: 2006-06-02
  • Acquisition Date: 2006-06-13