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The neural bases of training of working memory in elderly

Research Project

Project/Area Number 18330156
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Experimental psychology
Research InstitutionOsaka University of Foreign Studies

Principal Investigator

OSAKA Mariko  Osaka University of Foreign Studies, 人間科学研究科, 教授 (70144300)

Co-Investigator(Kenkyū-buntansha) 苧阪 直行  京都大学, 大学院・文学研究科, 教授 (20113136)
Co-Investigator(Renkei-kenkyūsha) OSAKA Naoyuki  京都大学, 文学研究科, 教授 (20113136)
Project Period (FY) 2006 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥17,630,000 (Direct Cost: ¥15,200,000、Indirect Cost: ¥2,430,000)
Fiscal Year 2008: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2007: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2006: ¥7,100,000 (Direct Cost: ¥7,100,000)
Keywordsワーキングメモリ / 高齢者 / 訓練 / 脳イメージング / 中央実行系 / 注意制御 / 抑制制御 / 前頭葉 / 注意 / 前頭前野 / 前部帯状回
Research Abstract

本研究は,高齢者を対象として,ワーキングメモリの注意制御機能を訓練により促進することを目的とした。訓練前後にワーキングメモリ課題(リーディングスパンテスト)遂行中の脳機能画像を撮像して,訓練効果を確かめた。訓練の結果,訓練前の脳活動には認められなかった前部帯状回の活動増強が認められた。この研究結果は,本実験で用いたイメージ訓練が注意の制御機能を高め,ワーキングメモリ機能を促進することを示唆するものである。

Report

(4 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (41 results)

All 2009 2008 2007 2006

All Journal Article (18 results) (of which Peer Reviewed: 13 results) Presentation (21 results) Book (2 results)

  • [Journal Article] 高齢者のワーキングメモリとその脳内機構2009

    • Author(s)
      苧阪満里子
    • Journal Title

      心理評論 53

      Pages: 276-288

    • NAID

      130007627105

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Individual differences in the theory of mind and superior temporal sulcus2009

    • Author(s)
      Otsuka, Y., Osaka, N., Ikeda, T., Osaka, M
    • Journal Title

      Neuroscience Letters 463

      Pages: 150-153

    • NAID

      120001587282

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Gaze-related mimic word activates the frontal eye field and related network in the human brain : An fMRI study2009

    • Author(s)
      苧阪満里子・苧阪直行
    • Journal Title

      Neuroscience Letters 461

      Pages: 65-68

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Is the self special in DMPFC? An fMRI study2009

    • Author(s)
      Yaoi, K., Osaka, M., Osaka, N.
    • Journal Title

      Social Neuroscience 4

      Pages: 455-463

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Individual differences in the theory of mind and superior temporal sulcus2009

    • Author(s)
      Otsuka, Y., Osaka, N., Ikeda, T., Osaka, M.
    • Journal Title

      Neuroscience Letters 463

      Pages: 150-153

    • NAID

      120001587282

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 記憶と言葉の理解をつなぐワーキングメモリ2009

    • Author(s)
      苧阪満里子・苧阪直行
    • Journal Title

      言語 38

      Pages: 46-53

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 高齢者のワーキングメモリとその脳内機構2009

    • Author(s)
      苧阪満里子
    • Journal Title

      心理学評論 53

      Pages: 276-288

    • NAID

      130007627105

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional asymmetry of superior parietal lobule for working memory in the elderly2008

    • Author(s)
      Otsuka, Y., Osaka, N., Osaka, M
    • Journal Title

      NeuroReport 19

      Pages: 1355-1359

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Functional asymmetry of superior parietal lobule for working memory in the elderly2008

    • Author(s)
      Otsuka, Y., Osaka, N., Osaka, M.
    • Journal Title

      Neuro Report 19

      Pages: 1355-1359

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ワーキングメモリの脳内表現2008

    • Author(s)
      苧阪満里子
    • Journal Title

      ワーキングメモリにおける注意のフォーカスと抑制の脳内表現」(京都大学学術出版会)

      Pages: 77-102

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Neural bases of focusing attention in working memory: An fMRI study based on group differences2007

    • Author(s)
      Osaka, M., Komori, M., Morishita, M., Osaka, N
    • Journal Title

      Cognitive, Affective, Behavioral Neuroscience 7

      Pages: 130-139

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transcranial magnetic stimulation (TMS) applied to left dorsolateral prefrontal cortex disrupts verbal working memory performance in humans2007

    • Author(s)
      Osaka, N., Otsuka, Y., Hirose, N., Ikeda, T., Mima, T., Fukuyama, H., Osaka, M
    • Journal Title

      Neuroscience Letters 418

      Pages: 232-235

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neural bases of focusing attention in working memory: An fMRI study based on group differences2007

    • Author(s)
      Osaka, M. Komori, M., Morishita, M., Osaka, N.
    • Journal Title

      Cognitive, Affective, & Behavioral Neuroscience 7

      Pages: 130-139

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2007

    • Author(s)
      M. Osaka & N. Osaka
    • Journal Title

      Neural bases of focusing attention in working memory: An fMRI study based on individual differences. In Osaka, N., Logie, R. H., & D'Esposito, M. (eds. ) The Cognitive Neuroscience of Working Meory(Oxford University Press)

      Pages: 99-117

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Neural bases of focusing attention in working memory:An fMRI study based on group differences.2007

    • Author(s)
      Mariko Osaka
    • Journal Title

      Cognitive Affective & Behavioral Neuroscience

      Pages: 130-139

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Decreased activation of anterior cingulate cortex in the working memory of the elderly2006

    • Author(s)
      Otsuka, Y., Osaka, N., Morishita, M., Kondo, H., Osaka, M
    • Journal Title

      NeuroReport No.17

      Pages: 1479-1482

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of strategy training on elderly working memory: an fMRI study.2006

    • Author(s)
      Mariko Osaka
    • Journal Title

      Society for Neuroscience Wendusday,77

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 高齢者のワーキングメモリの神経基盤-強化訓練の効果について2006

    • Author(s)
      苧阪満里子
    • Journal Title

      第4回日本ワーキングメモリ学会抄録集

      Pages: 10-10

    • NAID

      130007393219

    • Related Report
      2006 Annual Research Report
  • [Presentation] Inhibitory training produce: An fMRI based on group differences2009

    • Author(s)
      Osaka, M., Osaka, N
    • Organizer
      Proceeding of the SFN Neuroscience 2009 meeting
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-10-20
    • Related Report
      2008 Final Research Report
  • [Presentation] Incident encoding of goal-irrelevant information can be predicted by activation of the left middle frontal gyrus2009

    • Author(s)
      Minamoto, T., Osaka, M., Osaka, N
    • Organizer
      Society for Neuroscience 39th Annual Meeting
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-10-20
    • Related Report
      2008 Final Research Report
  • [Presentation] Incidental encoding of goal-irrelevant information can be predicted by activation of the left middleforntal gyrus : A preliminary fMRI study2009

    • Author(s)
      源健宏・苧阪満里子・苧阪直行
    • Organizer
      The 39th Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago, Illinois, USA
    • Year and Date
      2009-10-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] Training of inhibitory control of attention introduces effective control of executive function in elderly working memory : An fMRI study2009

    • Author(s)
      Osaka, M., Otsuka, Y., Kinoshita, Y., Yaoi, K., Osaka, N.
    • Organizer
      The 39th Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago, Illinois, USA
    • Year and Date
      2009-10-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] Functional a symmetry of the superior parietal lobule in working memory of the elderly2009

    • Author(s)
      Otsuka, Y., Osaka, N., Osaka, M
    • Organizer
      Working Memory Meeting 2009
    • Place of Presentation
      Shengen, Luxembourg
    • Year and Date
      2009-06-16
    • Related Report
      2008 Final Research Report
  • [Presentation] Functional asymmetry of the superior parietal lobule in working memory of the elderly2008

    • Author(s)
      大塚結喜・苧阪満里子・苧阪直行
    • Organizer
      International Seminar on "Neuroscience and Cognitive Control"
    • Place of Presentation
      Ghent, Belgium
    • Year and Date
      2008-12-10
    • Related Report
      2008 Annual Research Report
  • [Presentation] Functional asymmetry of the superior parietal lobule in working memory of the elderly2008

    • Author(s)
      Otsuka, Y., Osaka, N., Osaka, M
    • Organizer
      nternational Seminar on "Neuroscience and Cognitive control"
    • Place of Presentation
      Ghent, Belgium
    • Year and Date
      2008-12-05
    • Related Report
      2008 Final Research Report
  • [Presentation] Individual differences of working memory capacity related as the different pattern of functional connectivity during visual working memory task2008

    • Author(s)
      Minamoto, T., Osaka, M., Osaka, N
    • Organizer
      Society for Neuroscience 38th Annual Meeting
    • Place of Presentation
      Washington, D.C., USA
    • Year and Date
      2008-11-16
    • Related Report
      2008 Final Research Report
  • [Presentation] Individual differences of working memory capacity reflected as the different pattern of functional connectivity during visual working memory task2008

    • Author(s)
      源健宏・苧阪満里子・苧阪直行
    • Organizer
      The 38th Annual Meeting of the Society for Neurocience
    • Place of Presentation
      Washington, D.C., USA
    • Year and Date
      2008-11-16
    • Related Report
      2008 Annual Research Report
  • [Presentation] 高齢者において感情情報がワーキングメモリに及ぼす影響、言語性ワーキングメモリを用いた検討2008

    • Author(s)
      勝原摩耶, 大塚結喜, 苧阪満里子, 苧阪直行
    • Organizer
      日本心理学会
    • Year and Date
      2008-09-20
    • Related Report
      2008 Final Research Report
  • [Presentation] fMRIによる視覚性ワーキングメモリにおける情報保持に関わる神経基盤の検討ワーキングメモリ容量の個人差からのアプローチ2008

    • Author(s)
      源健宏・苧阪満里子・苧阪直行
    • Organizer
      日本心理学会
    • Place of Presentation
      札幌
    • Year and Date
      2008-09-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] 高齢者において感情情報がワーキングメモリに及ぼす影響―言語性ワーキングメモリ課題を用いた検討―2008

    • Author(s)
      勝原摩耶・大塚結喜・苧阪満里子・苧阪直行
    • Organizer
      日本心理学会
    • Place of Presentation
      札幌
    • Year and Date
      2008-09-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] 自己を含む人物表象へのメタ的評価とその脳内神経基盤2008

    • Author(s)
      矢追健・苧阪直行・苧阪満里子
    • Organizer
      日本心理学会
    • Place of Presentation
      札幌
    • Year and Date
      2008-09-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] 視覚性ワーキングメモリの情報保持に関わる神経基盤の検討-ワーキングメモリの個人差からのアプローチ2008

    • Author(s)
      源健宏, 苧阪満里子, 苧阪直行
    • Organizer
      日本ワーキングメモリ学会第5回大会
    • Place of Presentation
      京都(抄録)
    • Year and Date
      2008-03-08
    • Related Report
      2008 Final Research Report
  • [Presentation] 言語性ワーキングメモリの訓練効果:抑制機能の観点から2008

    • Author(s)
      木下侑里子、苧阪満里子
    • Organizer
      日本ワーキングメモリ学会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] リーディングスパンテストにおける注意制御と眼球運動2008

    • Author(s)
      十河宏行、佐藤貴之、大塚結喜、苧阪満里子、苧阪直行
    • Organizer
      日本ワーキングメモリ学会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] Proceeding of the Society for Neuroscience 37th Annual Meeting2007

    • Author(s)
      Osaka, M., Osaka, N
    • Organizer
      Society for Neuroscience 37th Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2007-11-06
    • Related Report
      2008 Final Research Report
  • [Presentation] Focusing of attention: An fMRI based on group differences2007

    • Author(s)
      N. Osaka & M. Osaka
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      San Diego(USA)
    • Year and Date
      2007-11-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] 言語性ワーキングメモリを支える脳内ネットワークに対する加齢の影響2007

    • Author(s)
      大塚結喜, 苧阪直行, 苧阪満里子
    • Organizer
      日本心理学会第71回発表論文集
    • Year and Date
      2007-09-20
    • Related Report
      2008 Final Research Report
  • [Presentation] ワーキングメモリにおける注意2007

    • Author(s)
      苧阪満里子
    • Organizer
      日本心理学会
    • Place of Presentation
      東京
    • Year and Date
      2007-08-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] Effect of training on elderly working memory: An fMRI study2006

    • Author(s)
      Osaka, M., Otsuka, Y., Osaka, N
    • Organizer
      Proceeding of the Society for Neuroscience 36th Annual Meeting
    • Place of Presentation
      Atlanta, USA
    • Year and Date
      2006-10-17
    • Related Report
      2008 Final Research Report
  • [Book] ワーキングメモリにおける注意のフォーカスと抑制の脳内表現2008

    • Author(s)
      苧阪満里子
    • Publisher
      京都大学学術出版会
    • Related Report
      2008 Final Research Report
  • [Book] Neural basis of focusing attention in working memory2007

    • Author(s)
      Osaka, M., Osaka, N
    • Publisher
      Oxford University Press
    • Related Report
      2008 Final Research Report

URL: 

Published: 2006-04-01   Modified: 2016-04-21  

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