Reductive Construction of Carbon Skeleton with Newly Designed Asymmetric Catalysts
| Project/Area Number |
18350049
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Nagoya University |
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Principal Investigator |
NISHIYAMA Hisao Nagoya University, 工学研究科, 教授 (40135421)
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| Project Period (FY) |
2006 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥17,400,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥1,800,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2007: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2006: ¥9,600,000 (Direct Cost: ¥9,600,000)
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| Keywords | 不斉合成 / 反応 / ロジウム / 有機金属 / 配位子 / 炭素結合形成 / 炭素炭素結合生成 / 不斉触媒 / オキサゾリン |
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| Research Abstract |
New synthetic method of carbon skeletons and functional transformation has been examined with designed transition metal species, which has chiral oxazoline ligands. Via intermediates activated by silane or hydrogen, coupling reaction of esters or enones with aldehydes was promoted to form optically active compounds with diastereo- and enantio-selectivities.
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Report
(6 results)
Research Products
(32 results)
