Mechanisms of Sensory Processing in C.elegans Neuronal Circuits.
Project/Area Number |
18370004
|
Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Genetics/Genome dynamics
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Research Institution | Kyushu University |
Principal Investigator |
ISHIHARA Takeshi Kyushu University, 大学院・理学研究院, 教授 (10249948)
|
Co-Investigator(Kenkyū-buntansha) |
KOGA Makoto 九州大学, 大学院・理学研究院, 准教授 (60243888)
FUJIWARA Manabi 九州大学, 大学院・理学研究院, 助教 (70359933)
HIROTSU Takaaki 九州大学, 大学院・理学研究院, 助教 (70404035)
|
Project Period (FY) |
2006 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥17,510,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥2,610,000)
Fiscal Year 2009: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2008: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2007: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2006: ¥6,200,000 (Direct Cost: ¥6,200,000)
|
Keywords | 行動遺伝学 / 学習 / 神経回路 / 情報処理 / 線虫 / 脳 / 情報伝達 / 行動 / 遺伝学 |
Research Abstract |
Animals sense variety of environmental stimuli in sensory neurons, simultaneously. This sensory information is processed in central nervous systems to regulate their behavior. In this study, we investigated mechanisms of the sensory processing by using C.elegans as a model organism. We identified signaling pathways to regulate the sensory integration and neuronal circuits where those pathways function. To elucidate the regulation of the memory retention, we isolated mutants showing longer memory retention and thereby identified a signaling pathway that regulates the memory retention. We found that the germline signals regulate the olfactory response. By using this phenomenon, we isolated a mutant defective in the regulation. In addition, we elucidated the function of signaling pathways for the olfactory sensation and behavioral plasticity.
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Report
(6 results)
Research Products
(77 results)
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[Journal Article] Left-right olfactory asymmetry results from antagonistic functions of voltage-activated calcium channels and the Raw repeat protein OLRN-1 in C. elegans.2007
Author(s)
Bauer Huang, SL., Saheki, Y., Vanhoven, MK., Torayama, I., Ishihara, T., Katsura, I, van der Linden, A., Sengupta, P., Bargmann, CI
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Journal Title
Neural Development 2
Pages: 24-24
Related Report
Peer Reviewed
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[Journal Article] Left-right olfactory asymmetry results from antagonistic functions of voltage-activated calcium channels and the Raw repeat protein OLRN-1 in C. elegans2007
Author(s)
Bauer Huang,SL., Saheki, Y., Vanhoven, MK., Torayama, I., Ishihara, T., Katsura, I, van der Linden, A., Sengupta, P. and Bargmann, CI.
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Journal Title
Neural Development 2
Pages: 24-24
Related Report
Peer Reviewed
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