Development of Exhaustive Synthesis of Glycopeptides by using Multiphase Organic Reaction System

• Project/Area Number: 18380071
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Bioproduction chemistry/Bioorganic chemistry
• Research Institution: Tokyo University of Agriculture and Technology
• Principal Investigator: CHIBA Kazuhiro Tokyo University of Agriculture and Technology, 大学院・連合農学研究科, 教授 (20227325)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥16,750,000 (Direct Cost: ¥15,100,000、Indirect Cost: ¥1,650,000); Fiscal Year 2008: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000); Fiscal Year 2007: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2006: ¥9,600,000 (Direct Cost: ¥9,600,000)
• Keywords: 糖鎖 / 有機化学 / 化学合成 / 生体分子 / 生理活性 / シクロアルカン / ペプチド / 糖質 / アミノ酸 / 液相合成 / オリゴ糖 / コンビナトリアル合成 / 二相溶液 / コンビナトリアルケミストリー

Research Abstract

本研究では、近年見出したシクロアルカン系有機溶媒相溶二相化現象を応用し、多様なオリゴ糖-ペプチド複合体標品のワンポット逐次多段階化学合成法を確立する新たな方法について研究を実施し、目的とする糖ペプチド合成システムを構築した。また、このシステムを応用し、オリゴ糖、糖ペプチドなど十数段階から数十段階を要する物質の簡易操作による合成に成功した。

Research Products

• [Journal Article] Anodic Carbon Carbon Bond Formation in Lithium Perchlorate/Nitromethane Electrolyte Solution (2009)
  • Author(s): Kazuhiro Chiba, Shokaku Kim
  • Journal Title: Electrochemistry Vol.77, No.1 Pages: 21-29
  • NAID: 130002150707
  • Peer Reviewed
• [Journal Article] Electrocatalytic Formal[2+2]Cycloaddition Reactions between Anodically Activated Aliphatic Enol Ethers and Unactivated Olefins Possessing an Alkoxyphenyl Group (2009)
  • Author(s): Yohei Okada, Ryoichi Akaba, Kazuhiro Chiba
  • Journal Title: Org. Lett. 11(4) Pages: 1033-1035
  • Peer Reviewed
• [Journal Article] Construction of Cold triggered/Heat destroyed Emulsions for Use as a Practical Cold Storage Thermal History Indicator (2009)
  • Author(s): Tatsuya Mizoguch, Kohdai Nagata, Makoto Kitsunai, Kumi Hirose, Akira Hirasawa, Kazuhiro Chiba
  • Journal Title: J.Sci.Food Agric. (in press)
  • Peer Reviewed
• [Journal Article] Anodic Carbon-Carbon Bond Formation in Lithium Perchlorate/Nitromethane Electrolyte Solution (2009)
  • Author(s): Kazuhiro Chiba, Shokaku Kim, Anodic Carbon-Carbon Bond Formation in Lithium Perchlorate/Nitromethane Electrolyte Solution
  • Journal Title: Electrochemistry 77(1) Pages: 21-29
  • NAID: 130002150707
  • Peer Reviewed
• [Journal Article] Electrocatalytic Formal [2+2] Cycloaddition Reactions between Anodically Activated Aliphatic Enol Ethers and Unactivated Olefins Possessing an Alkoxyphenyl Group (2009)
  • Author(s): Yohei Okada, Ryoichi Akaba, Kazuhiro Chiba
  • Journal Title: Org. Lett. 11(4) Pages: 1033-1035
  • Peer Reviewed
• [Journal Article] Construction of Cold-triggered/Heat-destroyed Emulsions for Use as a Practical Cold-storage Thermal History Indicator (2009)
  • Author(s): Tatsuya Mizoguch, Kohdai Nagata, Makoto Kitsunai, Kumi Hirose, Akira Hirasawa, Kazuhiro Chiba
  • Journal Title: J. Sci. Food Agric. 89(印刷中)
  • Peer Reviewed
• [Journal Article] Cold-triggered/Heat destroyed Emulsions Composed of Phospholipids and Triacylglycerols as Thermal History Indicators for Cold Chain Distribution Systems (2008)
  • Author(s): Kohdai Nagata, Tatsuya Mizoguchi, Makoto Kitsunai, Kumi Hirose, Akira Hirasawa, Kazuhiro Chiba
  • Journal Title: J. Sci. Food Agric. 88 Pages: 1019-1024
  • Peer Reviewed
• [Journal Article] A cycloalkane based thermomorphic system for palladium catalyzed cross coupling reactions (2008)
  • Author(s): Shokaku Kim, Keisuke Yamamoto, Kanako Hayashi, Kazuhiro Chiba
  • Journal Title: Tetrahedron 64(12) Pages: 2855-2863
  • Peer Reviewed
• [Journal Article] Solution Phase Oligosaccharide Synthesis in a Cycloalkane Based Thermomorphic System (2008)
  • Author(s): Shokaku Kim, Ai Tsuruyama, Akihiro Ohmori, Kazuhiro Chiba
  • Journal Title: Chem.Comm. Pages: 1816-1818
  • Peer Reviewed
• [Journal Article] An Oxidative Carbon-Carbon Bond Formation System in Cycloalkane Based Thermomorphic Multi Phase Solution (2008)
  • Author(s): Shokaku Kim, Satoko Noda, Kanako Hayashi, Kazuhiro Chiba
  • Journal Title: Org. Lett. 10(9) Pages: 1827-1829
  • Peer Reviewed
• [Journal Article] Phase separable Aqueous Amide Solutions as a Thermal History Indicator (2008)
  • Author(s): Makoto KITSUNAI, Kentaro MIYAJIMA, Yuzuru MIKAMI, Shokaku KIM, Akira HIRASAWA, Kazuhiro CHIBA
  • Journal Title: Biosci. Biotech.Biochem Vol.76, No.12 Pages: 871-873
  • NAID: 10027535598
  • Peer Reviewed
• [Journal Article] Construction of Cycloalkane based Thermomorphic(CBT)Electrolyte Solution Systems and Application for Anodic Conversion of a Furan Derivative (2008)
  • Author(s): Tomio NAGANO, Yuzuru MIKAMI, Shokaku KIM, Kazuhiro CHIBA
  • Journal Title: Electrochemistry Vol.76, No.12 Pages: 874-879
  • NAID: 130002150778
  • Peer Reviewed
• [Journal Article] Cyclic Voltammetric Studies on Anodic Cycloaddition Reactions between Electrogenerated Phenoxonium Cations and Alkenes (2008)
  • Author(s): Kumi HIROSE, Shokaku KIM, Kazuhiro CHIBA
  • Journal Title: Electrochemistry Vol.76, No.12 Pages: 871-873
  • NAID: 130002150777
  • Peer Reviewed
• [Journal Article] Cold-triggered/Heat-destroyed Emulsions Composed of Phospholipids and Triacylglycerols as Thermal History Indicators for Cold-Chain Distribution Systems (2008)
  • Author(s): Kohdai Nagata, Tatsuya Mizoguchi, Makoto Kitsunai, Kumi Hirose, Akira Hirasawa, Kazuhiro Chiba
  • Journal Title: J. Sci. Food Agric. 88 Pages: 1019-1024
  • Peer Reviewed
• [Journal Article] A cycloalkane-based thermomorphic system for palladium-catalyzed cross-coupling reactions (2008)
  • Author(s): Shokaku Kim, Keisuke Yamamoto, Kanako Hayashi, Kazuhiro Chiba
  • Journal Title: Tetrahedron 64(12) Pages: 2855-2863
  • Peer Reviewed
• [Journal Article] Solution-Phase Oligosaccharide Synthesis in a Cycloalkane-Based Thermomorphic System (2008)
  • Author(s): Shokaku Kim, Ai Tsuruyama, Akihiro Ohmori, Kazuhiro Chiba
  • Journal Title: Chem. Comm. 73 Pages: 1816-1818
  • Peer Reviewed
• [Journal Article] An Oxidative Carbon-Carbon Bond Formation System in Cycloalkane-Based Thermomorphic Multi-Phase Solution (2008)
  • Author(s): Shokaku Kim, Satoko Noda, Kanako Hayashi, Kazuhiro Chiba
  • Journal Title: Org. Lett. 10(9) Pages: 1827-1829
  • Peer Reviewed
• [Journal Article] Phase-separable Aqueous Amide Solutions as a Thermal History Indicator (2008)
  • Author(s): Makoto KITSUNAI, Kentaro MIYAJIMA, Yuzuru MIKAMI, Shokaku KIM, Akira HIRASAWA, Kazuhiro CHIBA
  • Journal Title: Biosci. Biotech. Biochem. 76(2) Pages: 871-873
  • NAID: 10027535598
  • Peer Reviewed
• [Journal Article] Construction of Cycloalkane-based Thermomorphic (CBT) Electrolyte Solution Systems and Application for Anodic Conversion of a Furan Derivative (2008)
  • Author(s): Tomio NAGANO, Yuzuru MIKAMI, Shokaku KIM, Kazuhiro CHIBA
  • Journal Title: Electrochemistry 76(12) Pages: 874-879
  • NAID: 130002150778
  • Peer Reviewed
• [Journal Article] Cyclic Voltammetric Studies on Anodic Cycloaddition Reactions between Electrogenerated Phenoxonium Cations and Alkenes (2008)
  • Author(s): Kumi HIROSE, Shokaku KIM, Kazuhiro CHIBA
  • Journal Title: Electrochemistry 76(12) Pages: 871-873
  • NAID: 130002150777
  • Peer Reviewed
• [Journal Article] Cold-triggered/Heat-destroyed Emulsions Composed of Phospholipids and Triacylglycerols as Thermal History Indicators for Cold-Chain Distribution Systems (2008)
  • Author(s): Kohdai Nagata, Tatsuya Mizoguchi, Makoto Kitsunai, Kumi Hirose, Akira Hirasawa and Kazuhiro Chiba
  • Journal Title: J. Sci. Food Agric. 88 Pages: 1019-1024
  • Peer Reviewed
• [Journal Article] A cycloalkane-based thermomorphic system for palladium-catalyzed cross-coupling reactions (2008)
  • Author(s): Shokaku Kim, Keisuke Yamamoto, Kanako Hayashi and Kazuhiro Chiba
  • Journal Title: Tetrahedron (印刷中)
  • Peer Reviewed
• [Journal Article] Solution-Phase Oligosaccharide Synthesis in a Cycloalkane-Based Thermomorphic System (2008)
  • Author(s): Shokaku Kim, Ai Tsuruyama, Akihiro Ohmori and Kazuhiro Chiba
  • Journal Title: Chem. Comm. Pages: 1816-1818
  • Peer Reviewed
• [Journal Article] An Oxidative Carbon-Carbon Bond Formation System in Cycloalkane-Based Thermomorphic Multi-Phase Solution (2008)
  • Author(s): Shokaku Kim, Satoko Noda, Kanako Hayashi and Kazuhiro Chiba
  • Journal Title: Org. Lett. (印刷中)
  • Peer Reviewed
• [Journal Article] Laser Raman Detection of an Electrogenerated Intermediate during Anodic Synthesis of Dihydrobenzofurans via Formal [3+2] Cycloaddition (2007)
  • Author(s): Tomohiro Marui, Shinya Kajita, Yoshihiro Katayama, Kazuhiro Chiba
  • Journal Title: Electrochem. Commun. 9 Pages: 1331-1336
  • Peer Reviewed
• [Journal Article] シクロアルカン可溶化疎水性タグを用いた化学プロセスの効率化,"化学工業" (2007)
  • Author(s): 千葉一裕
  • Journal Title: (特集)コンビナトリアルケミストリーの新展開 VOL.58, No.4 Pages: 281-287
  • Peer Reviewed
• [Journal Article] Electrocatalytic Formal [2+2] Cycloaddition Reactions between Anodically Activated Enyloxy Benzene and Alkenes (2007)
  • Author(s): Arata, M. ; Miura, T. ; Chiba, K
  • Journal Title: Org. Lett. 9(21) Pages: 4347-4350
  • Peer Reviewed
• [Journal Article] Electrocatalytic Formal [2+2] Cycloaddition Reactions between Anodically Activated Enyloxy Benzene and Alkenes (2007)
  • Author(s): Arata, M.; Miura, T.; Chiba, K.
  • Journal Title: Org. Lett. 9(21) Pages: 4347-4350
  • Peer Reviewed
• [Journal Article] Laser Raman Detection of an Electrogenerated Intermediate during Anodic Synthesis of Dihydrobenzofurans via Formal [3+2] Cycloaddition (2007)
  • Author(s): Tomohiro Marui, Shinya Kajita, Yoshihiro Katayama, Kazuhiro Chiba
  • Journal Title: Electrochem.Commun (in press)
• [Journal Article] Rate Enhancement of Diels Alder Reactions in Aqueious Perfluorinated Emulsions (2006)
  • Author(s): Kohsuke Nishimoto, Shokaku Kim, Yoshikazu Kitano, Masahiro Tada, Kazuhiro Chiba
  • Journal Title: Org. Lett. 8(24) Pages: 5545-5547
  • Peer Reviewed
• [Journal Article] A convenient method for the preparation of benzyl isocyanides (2006)
  • Author(s): Kitano, Yoshikazu ; Manoda, Tetsuya ; Miura, Teppei ; Chiba, Kazuhiro ; Tada, Masahiro
  • Journal Title: Synthesis (3) Pages: 405-410
  • Peer Reviewed
• [Journal Article] Microwave promoted Suzuki Miyaura coupling reactions in a ycloalkane based thermomorphic biphasic system (2006)
  • Author(s): Hayashi, Kanako ; Kim, Shokaku ; Kono, Yusuke ; Tamura, Mihoko ; Chiba, Kazuhiro
  • Journal Title: Tetrahedron Letters 47(2) Pages: 171-174
  • Peer Reviewed
• [Journal Article] Electrochemical Enol Ether Olefin Cross Metathesis in a Lithium Perchlorate Nitromethane Electrolyte Solution (2006)
  • Author(s): Teppei Miura, Shokaku Kim, Yoshikazu Kitano, Masahiro Tada, Kazuhiro Chiba
  • Journal Title: Angew. Chem. Int. Ed. 45(9) Pages: 1461-1463
  • Peer Reviewed
• [Journal Article] Cycloalkane based Thermomorphic Electrochemical Reaction System Composed of Nitrile solvents (2006)
  • Author(s): Fumiyoshi Tanaka, Michiko Arata, Kanako Hayashi, Shokaku Kim and Kazuhiro Chiba
  • Journal Title: Electrochemistry 74(8) Pages: 625-627
  • NAID: 10017390050
  • Peer Reviewed
• [Journal Article] Reversible capture of electrogenerated intermediates by liquefiable micro particles containing an amphiphilic tag (2006)
  • Author(s): Kanako Hayashi, Shokaku Kim, and Kazuhiro Chiba
  • Journal Title: Electrochemistry 74(8) Pages: 621-624
  • NAID: 10017390017
  • Peer Reviewed
• [Journal Article] A convenient method for the preparation of benzyl isocyanides (2006)
  • Author(s): Kitano, Yoshikazu, Manoda, Tetsuya, Miura, Teppei, Chiba, Kazuhiro, Tada, Masahiro
  • Journal Title: Synthesis 3 Pages: 405-410
• [Journal Article] Rate Enhancement of Diels-Alder Reactions in Aqueious Perfluorinated Emulsions (2006)
  • Author(s): Kohsuke Nishimoto, Shokaku Kim, Yoshikazu Kitano, Masahiro Tada, Kazuhiro Chiba
  • Journal Title: Org. Lett 8(24) Pages: 5545-5547
• [Journal Article] Reversible capture of electrogenerated intermediates by liquefiable micro-particles containing an amphiphilic tag (2006)
  • Author(s): Kanako Hayashi, Shokaku Kim, Kazuhiro Chiba
  • Journal Title: Electrochemistry 74(8) Pages: 621-624
  • NAID: 10017390017
• [Journal Article] Cycloalkane-based Thermomorphic Electrochemical Reaction System Composed of Nitrile-solvents (2006)
  • Author(s): Fumiyoshi Tanaka, Michiko Arata, Kanako Hayashi, Shokaku Kim, Kazuhiro Chiba
  • Journal Title: Electrochemistry 74(8) Pages: 625-627
  • NAID: 10017390050
• [Journal Article] Electrochemical Enol Ether-Olefin Cross-Metathesis in a Lithium Perchlorate-Nitromethane Electrolyte Solution. (2006)
  • Author(s): Teppei Miura, Shokaku Kim, Yoshikazu Kitano, Masahiro Tada, Kazuhiro Chiba
  • Journal Title: Angew.Chem.Int.Ed. 45(9) Pages: 1461-1463
• [Journal Article] Microwave-promoted Suzuki-Miyaura coupling reactions in a cycloaokane-based thermomorphic biphasic system (2006)
  • Author(s): Hayashi, Kanako, Kim, Shokaku, Kono, Yusuke, Tamura, Mihoko, Chiba, Kazuhiro
  • Journal Title: Tetrahedron Letters 47(2) Pages: 171-174
• [Presentation] 触媒電気量で進行する [2+2] 付加環化反応 (2009)
  • Author(s): 岡田洋平, 赤羽良一, 千葉一裕
  • Organizer: 電気化学会大会
  • Place of Presentation: 京都大学
  • Year and Date: 2009-03-30
• [Presentation] 疎水性担体を用いた一容器内液相オリゴペプチド合成法の開発 (2009)
  • Author(s): 尾関歩未, 吉岡朋彦, 金承鶴, 千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: マリンメッセ福岡
  • Year and Date: 2009-03-28
• [Presentation] フェノール誘導体の電解反応による蛍光物質の探索合成 (2009)
  • Author(s): 植松潤平, 廣瀬久美, 千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: マリンメッセ福岡
  • Year and Date: 2009-03-28
• [Presentation] 熱応答磁性ナノ粒子反応場の構築 (2009)
  • Author(s): 西村宗親, 飯島志行, 金承鶴, 千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: マリンメッセ福岡
  • Year and Date: 2009-03-28
• [Presentation] 相溶二相系を用いたペプチドフロー合成 (2009)
  • Author(s): 小池幹男, 千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: マリンメッセ福岡
  • Year and Date: 2009-03-28
• [Presentation] 疎水性タグを用いたペプチド誘導体の液相合成 (2009)
  • Author(s): 有吉佐奈恵, 千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: マリンメッセ福岡
  • Year and Date: 2009-03-28
• [Presentation] 有機電解合成法によるジヒドロベンゾフラン誘導体の合成 (2009)
  • Author(s): 中山英, 岡田洋平, 三上由鶴, 金承鶴, 千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: マリンメッセ福岡
  • Year and Date: 2009-03-28
• [Presentation] ペプチドの多段階液相合成 (2009)
  • Author(s): ゲゲンタナ, 藤田, 千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: マリンメッセ福岡
  • Year and Date: 2009-03-28
• [Presentation] Diels-Alder 反応の促進効果を有するフルオラス溶媒-シリカ反応場の構築 (2009)
  • Author(s): 大岡直哉, 西本浩介, 千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: マリンメッセ福岡
  • Year and Date: 2009-03-28
• [Presentation] プロリン誘導体の電解合成 (2009)
  • Author(s): 河合朋充, 山本圭介, 千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: マリンメッセ福岡
  • Year and Date: 2009-03-28
• [Presentation] 触媒電気量で進行する [2+2] 付加環化反応 (2009)
  • Author(s): 岡田洋平, 赤羽良一, 千葉一裕
  • Organizer: 日本化学会春季年会
  • Place of Presentation: 日本大学理工学部
  • Year and Date: 2009-03-26
• [Presentation] (2009)
  • Author(s): 岡田洋平・赤羽良一・千葉一裕
  • Organizer: 日本化学会春季年会
• [Presentation] (2009)
  • Author(s): 岡田洋平・赤羽良一・千葉一裕
  • Organizer: 電気化学会大会
• [Presentation] 簡易操作による多段階反応を実現する液相化学プロセス (2008)
  • Author(s): 千葉一裕
  • Organizer: 第27回Combinatorial Chemistry 研究会
  • Place of Presentation: 東京工業大学・大岡山キャンパス
  • Year and Date: 2008-09-24
• [Presentation] 温度感受性相溶二相溶媒を用いた連続相分離フロー電解システム (2008)
  • Author(s): 吉岡朋彦, 金承鶴, 千葉一裕
  • Organizer: 第32回有機電子移動討論会
  • Place of Presentation: 近畿大学本部キャンパス
  • Year and Date: 2008-06-27
• [Presentation] フルオラス反応場を用いた電解合成 (2008)
  • Author(s): 大岡直哉, 千葉一裕
  • Organizer: 第32回有機電子移動討論会
  • Place of Presentation: 近畿大学本部キャンパス
  • Year and Date: 2008-06-27
• [Presentation] プロリン誘導体の電解合成 (2008)
  • Author(s): 河合朋充, 杉原万理, 千葉一裕
  • Organizer: 第32回有機電子移動討論会
  • Place of Presentation: 近畿大学本部キャンパス
  • Year and Date: 2008-06-27
• [Presentation] 触媒電気量で進行するシクロブタン環形成反応 (2008)
  • Author(s): 岡田洋平, 赤羽良一, 千葉一裕
  • Organizer: 第32回有機電子移動討論会
  • Place of Presentation: 近畿大学本部キャンパス
  • Year and Date: 2008-06-26
• [Presentation] A New Electrocatalytic [2+2] Cross-Coupling Reaction Supported by a “Redox Tag" for Anodic EC-backward-E Process (2008)
  • Author(s): Yohei Okada, Ryoichi Akaba, Kazuhiro Chiba
  • Organizer: 213^<th> Electrochemical Society Meeting
  • Place of Presentation: アメリカ合衆国、Phoenix Convention Center
  • Year and Date: 2008-05-20
• [Presentation] Continuous Phase-Separable Electrolytic System by using Cyclohexane-Based Thermomorphic Solutions (2008)
  • Author(s): Tomohiko Yoshioka, Shokaku Kim, Kazuhiro Chiba
  • Organizer: 213^<th> Electrochemical Society Meeting
  • Place of Presentation: アメリカ合衆国、Phoenix Convention Center
  • Year and Date: 2008-05-20
• [Presentation] Cyclic Voltammetric Studies for the Acceleration Property of Diels-Alder Reactions in Fluorous Micellar System (2008)
  • Author(s): K. Nishimoto, S. Kim, K. Chiba
  • Organizer: 213^<th> Electrochemical Society Meeting
  • Place of Presentation: アメリカ合衆国、Phoenix Convention Center
  • Year and Date: 2008-05-20
• [Presentation] Cyclic Voltammetric Studies on the Anodic Cycloaddition of Electrogenerated Phenoxonium Cations and Alkenes (2008)
  • Author(s): Kumi Hirose, Kohsuke Nishimoto, Shokaku Kim, Kazuhiro Chiba
  • Organizer: 213^<th> Electrochemical Society Meeting
  • Place of Presentation: アメリカ合衆国、Phoenix Convention Center
  • Year and Date: 2008-05-20
• [Presentation] サイクリックボルタンメトリーによるフェノキソニウムカチオンの特性評価 (2008)
  • Author(s): 廣瀬 久美・金 承鶴・千葉 一裕
  • Organizer: 電気化学会大会
  • Place of Presentation: 山梨大学工学部
  • Year and Date: 2008-03-31
• [Presentation] フッ素反応場を利用した選択的電解合成 (2008)
  • Author(s): 大岡直哉, 金承鶴, 千葉一裕
  • Organizer: 電気化学会大会
  • Place of Presentation: 山梨大学工学部
  • Year and Date: 2008-03-29
• [Presentation] 相溶二相電解質溶液を用いたフラン誘導体の電解反応 (2008)
  • Author(s): 永野富郎、三上由鶴, 金承鶴、千葉一裕
  • Organizer: 電気化学会大会
  • Place of Presentation: 山梨大学工学部
  • Year and Date: 2008-03-29
• [Presentation] 二相液相法によるペプチド誘導体の検体自動合成 (2008)
  • Author(s): 有吉佐奈恵、山本清野香、金承鶴、千葉一裕
  • Organizer: 日本農芸化学会大会
  • Place of Presentation: 名城大学
  • Year and Date: 2008-03-27
• [Presentation] (2008)
  • Author(s): 岡田洋平、赤羽良一、千葉一裕
  • Organizer: 第32回有機電子移動討論会
• [Presentation] (2008)
  • Author(s): 吉岡朋彦・金承鶴・千葉一裕
  • Organizer: 第32回有機電子移動討論会
• [Presentation] (2008)
  • Author(s): 大岡直哉・千葉一裕
  • Organizer: 第32回有機電子移動討論会
• [Presentation] (2008)
  • Author(s): 河合朋充・杉原万理・千葉一裕
  • Organizer: 第32回有機電子移動討論会
• [Presentation] (2008)
  • Author(s): Yohei Okada, Ryoichi Akaba, Kazuhiro Chiba
  • Organizer: 213^<th> Electrochemical Society Meeting
• [Presentation] (2008)
  • Author(s): Tomohiko Yoshioka, Shokaku Kim, Kazuhiro Chiba
  • Organizer: 213^<th> Electrochem.Soc. Meeting
• [Presentation] (2008)
  • Author(s): K.Nishimoto, S.Kim, K.Chiba
  • Organizer: 213^<th> Electrochem. Soc. Meeting
• [Presentation] (2008)
  • Author(s): Kumi Hirose, Kohsuke Nishimoto, Shokaku Kim, Kazuhiro Chiba
  • Organizer: 213^<th> Electrochem.Soc. Meeting
• [Presentation] (2008)
  • Author(s): 千葉一裕
  • Organizer: 第27回Combinatorial Chemistry研究会
• [Presentation]
  • Author(s): 尾関歩未、吉岡朋彦、金承鶴、千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
• [Presentation]
  • Author(s): 植松潤平、廣瀬久美、千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
• [Presentation]
  • Author(s): 西村宗親、飯島志行、金承鶴、千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
• [Presentation]
  • Author(s): 小池幹男・千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
• [Presentation]
  • Author(s): 有吉佐奈恵・千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
• [Presentation]
  • Author(s): 中山英、岡田洋平、三上由鶴、金承鶴、千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
• [Presentation]
  • Author(s): ゲゲンタナ・藤田・千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
• [Presentation]
  • Author(s): 大岡直哉, 西本浩介, 千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
• [Presentation]
  • Author(s): 河合朋充・山本圭介・千葉一裕
  • Organizer: 日本農芸化学会2009年度大会
• [Book] 食品流通の安全を監視する温度履歴センサーシール (2008)
  • Author(s): 千葉一裕
  • Publisher: 食品と技術
• [Book] アフィニティー解析法、"分子間相互作用解析ハンドブック-タンパク質とタンパク質・核酸・糖・低分子間のネットワーク解析"(磯辺俊明、中山敬一、伊藤隆司(編集)) (2007)
  • Author(s): 高橋信弘、藤山沙理、千葉一裕
  • Publisher: 羊土社
• [Book] Development of Solution Phase Peptide Synthesis Protocol toward Automatic Synthesizer by Using Precipitation Method, Peptide Science(S.Aimoto, S. Ono (Eds.)) (2007)
  • Author(s): A. Tsuruyama, K. Abe, T. Higashiguchi, T Yoshioka, K. Chiba
  • Publisher: The Japanese Peptide Society
• [Book] Development of an Automatic Solution Phase Peptide Synthesizer, Peptide Science(S.Aimoto, S. Ono (Eds.)) (2007)
  • Author(s): K. Abe, A. Tsuruyama, T. Higashiguchi, K. Chiba
  • Publisher: The Japanese Peptide Society
• [Book] One Pod Solution Phase Peptide Synthesis Using Less Polar Platforms, Peptide Science(S.Aimoto S. Ono(Eds.)) (2007)
  • Author(s): T. Yoshioka, S. Yamamoto, M. Shimizu, S. Kim, K. Chiba
  • Publisher: The Japanese Peptide Society
• [Book] Synthesis of Various Proline Derivatives Using Organic Electrochemical Methods, Peptide Science(S. Aimoto, S. Ono (Eds.)) (2007)
  • Author(s): K. Yamamoto, M. Sugihara, S. Kim, K. Chiba
  • Publisher: The Japanese Peptide Society
• [Book] アフイニティー解析法 (2007)
  • Author(s): 高橋信弘、藤山沙理、千葉一裕
  • Publisher: 羊土社