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Standard Methods and Nutritional biochemistry for Production ofRadical-free Healthy Meats

Research Project

Project/Area Number 18380157
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Zootechnical science/Grassland science
Research InstitutionTohoku University

Principal Investigator

TOYOMIZU Masaaki  Tohoku University, 大学院・農学研究科, 教授 (80180199)

Co-Investigator(Kenkyū-buntansha) MIYAZAWA Teruo  東北大学, 大学院・農学研究科, 教授 (20157639)
Project Period (FY) 2006 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥12,760,000 (Direct Cost: ¥10,900,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2008: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2007: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2006: ¥4,700,000 (Direct Cost: ¥4,700,000)
Keywords活性酵素 / ミトコンドリア / ブロイラ- / 暑熱 / プロトンリ-ク / 栄養制御 / 脱共役タンパク質 / UCP / 活性酸素 / ブロイラー / プロトンリーク / 脱共役たんぱく質 / フロンティア環境 / 肉用鶏ブロイラー / 暑熱ストレス / 膜電位
Research Abstract

家畜・家禽は、外部刺激によるストレス条件下では生体構成成分の過酸化が生じ、生産性が低下する。本研究では、暑熱ストレス時においても「ラジカルフリーの健康肉」を設計するため栄養制御による飼養技術基盤を構築した。すなわち、暑熱ストレス下では02・-産生の増加が、脱共役タンパク質低下ならびに基質酸化の上昇→膜電位の上昇→02・-産生増大との「カスケード」が存在するが、オリ-ブ油の給与によりこの流れを負に制御することに成功した。

Report

(4 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (12 results)

All 2009 2008 2007 2006

All Journal Article (12 results) (of which Peer Reviewed: 9 results)

  • [Journal Article] Olive oil-supplemented diet alleviates acute heat stress-induced mitochondrial ROS production in chicken skeletal muscle2009

    • Author(s)
      Mujahid A., Y.Akiba and M. Toyomizu
    • Journal Title

      American Journal of Physiology (in press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Progressive Changes in thephysiological responses of heat-stressed broiler chickens2009

    • Author(s)
      Mujahid A., Y.Akiba, M.Toyomizu
    • Journal Title

      J.Poult.Sci 46

      Pages: 163-167

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Progressive changes in the physiological responses of heat-stressed broiler chickens2009

    • Author(s)
      Ahmad M., Akiba Y., Toyomizu M.
    • Journal Title

      J. Poul t. Sci. 46

      Pages: 163-167

    • NAID

      10024799619

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tocotrienol Contents in Hen Eggs : its Fortification by Supplementing Rice Bran Scum Oil into Feeds2008

    • Author(s)
      Phumon SOOKWONG, Kiyotaka NAKAGAWA Shin-ichi NAKAJIMA, Yoshikazu AMANO, Masaaki TOYOMIZU, and Teruo MIYAZAWA
    • Journal Title

      Biosci. Biotechnol. Biochem 72(11)

      Pages: 3044-3047

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sequential changes in superoxide production, anion carriers and substrate oxidation in skeletal muscle mitochondria of heat-stressed chickens2007

    • Author(s)
      Mujahid A., Y.Akiba, Warden CH, M.Toyomizu
    • Journal Title

      FEBS Letters 581

      Pages: 3461-3467

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mitochondrial Oxidative Damage in Chicken Skeletal Muscle Induced by Acute Heat Stress2007

    • Author(s)
      MUJAHID A., N.R.Pumford, W.Bottje, K.Nakagawa, T.Miyazawa, Y.Akiba, M.Toyomizu
    • Journal Title

      J.Poult.Sci 44(4)

      Pages: 439-445

    • NAID

      10019768438

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Acute heat stress induces oxidative stress and decreases adaptation in young white leghorn cockerels bydownregulation of avian uncoupling protein2007

    • Author(s)
      Mujahid A, K.Sato, Y.Akiba, M.Toyomizu
    • Journal Title

      Poult sci 86

      Pages: 364-371

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sequential changes in superoxide production, anion carriers and substrate oxidation in skeletal muscle mitochondria of heat-stressed chickens.2007

    • Author(s)
      Mujahid A, Akiba Y, Warden C H, Toyomizu M.
    • Journal Title

      FEBS Letters 581

      Pages: 3461-3467

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute heat stress induces oxidative stress and decreases adaptation in young white leghorn cockerels by downregulation of avian uncoupling protein.2007

    • Author(s)
      Mujahid A.
    • Journal Title

      Poult Sci. 86

      Pages: 364-371

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Mitochondrial Oxidative Damage in Chicken Skeletal Muscle Induced by Acute Heat Stress.2007

    • Author(s)
      Mujahid A.
    • Journal Title

      J Poult Sci. (In press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Acute heat stress stimulatesmitochondrial superoxide production in broiler skeletal muscle, possibly via down- regulation of uncoupling protein content2006

    • Author(s)
      Mujahid A., K.Sato, Y.Akiba, M.Toyomizu
    • Journal Title

      Poult Sci 85

      Pages: 1259-1265

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Acute heat stress stimulates mitochondrial superoxide production in broiler skeletal muscle, possibly via down-regulation of uncoupling protein content.2006

    • Author(s)
      Mujahid, A.
    • Journal Title

      Poult Sci. 85

      Pages: 1259-1265

    • Related Report
      2006 Annual Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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