Study for development of specific diagnosis methods and effects of novel rickettsial infections on large animal pathogenesis and productivity

• Project/Area Number: 18380185
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Clinical veterinary science
• Research Institution: Obihiro University of Agriculture and Veterinary Medicine
• Principal Investigator: INOKUMA Inokuma Obihiro University of Agriculture and Veterinary Medicine, 畜産学部, 教授 (70263803)
• Co-Investigator(Kenkyū-buntansha): YOKOYAMA Naoaki 帯広畜産大学, 原虫病研究センター, 准教授 (80301802) ; MIYAKE Youichi 帯広畜産大学, 畜産学部, 教授 (20002256) ; ISHII Mitsuo 帯広畜産大学, 原虫病研究センター, 准教授 (80419960) ; HIRAI Katsuya 天使大学, 栄養学部, 教授 (30021702) ; 田邊 茂之 帯広畜産大学, 畜産学部, 助教授 (70292092)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥14,460,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥2,160,000); Fiscal Year 2008: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2007: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2006: ¥5,100,000 (Direct Cost: ¥5,100,000)
• Keywords: リケッチア / 新興感染症 / 診断 / 産業動物 / 生産性 / エールリヒア / アナプラズマ / 野生動物 / マダニ

Research Abstract

我が国に生息するエーリキア類に対する特異的PCR、および紅斑熱リケッチア種を鑑別するPCR-RFLP 法を開発し、マダニと野生動物に新規病原性リケッチアが常在していることが明らかとなった。また牛末梢血からAnaplasma phagocytophilumおよびAnaplasmabovis近縁の遺伝子が検出され、わが国の牛がこれら病原体に感染していることが明らかとなった。しかし感染牛はとくに異常な症状を呈しておらず、また遺伝子解析では我が国の病原体は既知種とは別種である可能性が示唆され、病原性も異なる可能性が考えられた。

Research Products

• [Journal Article] Anaplasma marginale infection in a Japanese Black cow occurred 13 years after eradication of Rhipicephalus(Boophilus)microplus in Okinawa, Japan. (2009)
  • Author(s): Ooshiro, M., Zakimi, S., Matsukawa, Y., Yafuso, M., Katagiri, Y., Inokuma, H
  • Journal Title: Vet.Parasitol 160 Pages: 351-355
  • Peer Reviewed
• [Journal Article] Molecular survey for Anaplasma bovis and Anaplasma phagocytophilum infection in cattle in a pastureland where sika deer appear in Japan (2009)
  • Author(s): Jilintai, Seino, N., Hayakawa, D., Suzuki, M., Hata, H., Kondo, S., Matsumoto, K., Yokoyama, N., Inokuma, H.
  • Journal Title: Jpn.J.Infect.Dis 62(1) Pages: 73-75
  • Peer Reviewed
• [Journal Article] Molecular survey for Anaplasma bovis and Anaplasma phagocytophilum infection in cattle in a pastureland where sika deer appear in Japan (2009)
  • Author(s): Jilintai, Seino, N., Hayakawa, D., Suzuki, M., Hata, H., Kondo, S., Matsumoto. K.. Yokovama. N..Inokuma. H.
  • Journal Title: Japanese Journal of Infectious Diseases 62 Pages: 73-75
  • Peer Reviewed
• [Journal Article] Anaplasma marginale infection in a Japanese Black cow occurred 13 years after eradication of Rhipicephalus (Boophilus) microplus, in Okinawa, Japan (2009)
  • Author(s): Ooshiro, M., Zakimi, S., Matsukawa, Y., Yafuso, M., Katagiri. Y. Inokuma, H.
  • Journal Title: Veterinary Parasitology 160 Pages: 351-355
  • Peer Reviewed
• [Journal Article] Identification of spotted fever group Rickettsia species by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analvsis of the Sca4 gene (2009)
  • Author(s): Matsumoto K. Inokuma H.
  • Journal Title: Vector-Borne Diseases (In press)
  • Peer Reviewed
• [Journal Article] Molecular detection of Mycoplasma wenyonii and 'Candidatus Mycoplasma haemobos' in cattle in Japan (2008)
  • Author(s): Tagawa, M., Matsumoto, K., Inokuma, H
  • Journal Title: Vet.Microbiol 132(1-2) Pages: 177-180
  • Peer Reviewed
• [Journal Article] 話題の感染症エーリキア症 (2008)
  • Author(s): 猪熊 壽
  • Journal Title: モダンメディア 54(5) Pages: 135-143
• [Journal Article] Serological and molecular survey of Rickettsia infection in cattle and sika deer in a pastureland in Hidaka district, Hokkaido, Japan (2008)
  • Author(s): Jilintai, Seino, N., Matsumoto, K., Hayakawa, D., Suzuki, M., Hata, H., Kondo, S., Yokoyama, N., Inokuma, H.
  • Journal Title: Jpn.J.Infect.Dis 61(4) Pages: 315-317
  • Peer Reviewed
• [Journal Article] Detection of Anaplasma bovis and Anaplasma phagocytophilum from cattle on Yonaguni Island, Okinawa, Japan (2008)
  • Author(s): Ooshiro, M., Zakimi, S, Matsukawa, Z., Katagiri, Y., Inokuma, H.
  • Journal Title: Vet.Parasitol 154(3-4) Pages: 360-364
  • Peer Reviewed
• [Journal Article] Detection of Rickettsia helvetica DNA from peripheral blood of sika deer(Cervus nippon yesoensis)in Japan (2008)
  • Author(s): Inokuma H., Seino, N., Suzuki, M., Kaji, K., Takahashi, H., Inoue, S.
  • Journal Title: J.Wildl. Dis 44(1) Pages: 164-167
  • Peer Reviewed
• [Journal Article] Detection of Rickettsia helvetica DNA from peripheral blood of sik a deer (Cervus nippon yesoensis) in Japan (2008)
  • Author(s): Inokuma H., Seino, N., Suzuki,M., Kaji, K., Takahashi, H., Inoue, S.
  • Journal Title: Journal of Wildlife Diseases 44 Pages: 164-167
  • Peer Reviewed
• [Journal Article] Detection of Anaplasma bovis and Anaplasma phagocytophilum from cattle on Yonaguni Island, Okinawa, Japan (2008)
  • Author(s): Ooshiro, M., Zakimi, S, Matsukawa, Z., Katagiri, Y., Inokuma. H.
  • Journal Title: Veterinary Parasitology 154 Pages: 360-364
  • Peer Reviewed
• [Journal Article] Serological and molecular survey of Rickettsia infection in cattle and sika deer in a pastureland in Hidaka district, Hokkaido, Japan (2008)
  • Author(s): Jilintai, Seino, N., Matsumoto, K., Hayakawa, D., Suzuki, M., Hata, H., Kondo. S., Yokovama. N. Inokuma, H.
  • Journal Title: Japanese Journal of Infectious Diseases 61 Pages: 315-317
  • Peer Reviewed
• [Journal Article] Molecular detection of Mycoplasma wenyonii and 'Candidatus Mvcoolasma haemobos' in cattle in Japan (2008)
  • Author(s): Tagawa, M., Matsumoto, K., Inokuma, H.
  • Journal Title: Veterinary Microbiology 31 Pages: 177-180
  • Peer Reviewed
• [Journal Article] Development of arapid immunochromatographictest for simultaneous serodiagnosisof bovine Babesioses caused by Babesia bovis and Babesia bigemina. (2008)
  • Author(s): Kim, C., Blanco, L. B. C., Alhassan, A., Iseki, H., Yokoyama, N., Xuan, X., Igarashi, I.
  • Journal Title: American Journal of Tropical Medicine and Hygine 78 Pages: 117-121
  • Peer Reviewed
• [Journal Article] Detection of Rickettsia helvetica DNA from peripheral blood of sika deer(Cervus nippon yesoensis)in Japan. (2008)
  • Author(s): Inokuma H., Seino, N., Suzuki, M., Kaji, K., Takahashi, H., Inoue, S.
  • Journal Title: Journal of Wildlife Diseases 44 Pages: 164-167
  • Peer Reviewed
• [Journal Article] Diagnostic real-time PCR assay for the quantitative detection of Theileria equi from equine blood samples (2007)
  • Author(s): Kim, C., Blanco, L. B. C., Alhassan, A., Iseki, H., Yokoyama, N., Xuan, X., and Igarashi, I.
  • Journal Title: Vet.Parasitol. 151 Pages: 158-163
  • Peer Reviewed
• [Journal Article] Development of a Multiplex Loop-Mediated Isothermal Amplification(mLAMP)Method for the Simultaneous Detection of Bovine Babesia Parasites (2007)
  • Author(s): Iseki, H, Alhassan, A, Ohta, N., Thekisoe, O. M. M., Yokoyama, N., Inoue, N., Nambota, A., Yasuda, J., and Igarashi, I.
  • Journal Title: J.Microbiol. Methods 71 Pages: 281-287
  • Peer Reviewed
• [Journal Article] Development of two immunochromatographic tests for the serodiagnosis of bovine babesiosis (2007)
  • Author(s): Kim, C., Alhassan, A., Verdida, R. A., Yokoyama, N., Xuan, X., Fujisaki, K., Kawazu, S, and Igarashi, I.
  • Journal Title: Vet.Parasitol 148 Pages: 137-143
  • Peer Reviewed
• [Journal Article] Comparative evaluation of the sensitivity of LAMP, PCR and In vitro culture methods for diagnosis of equine piroplasmosis (2007)
  • Author(s): Alhassan, A., Govind, Y., Tam, N. T., Thekisoe, O. M. M., Yokoyama, N., Igarashi, I.
  • Journal Title: Parasitol. Res. 100 Pages: 1165-1168
  • Peer Reviewed
• [Journal Article] Detection of Ehrlichia muris DNA from sika deer(Cervus nippon yesoensis)in Hokkaido, Japan (2007)
  • Author(s): Tamamoto, C., Seino, N., Jilintai, Suzuki, M., Kaji, K., Takahashi, H., Inokuma, H.
  • Journal Title: Vet.Parasitol 150 Pages: 370-373
  • Peer Reviewed
• [Journal Article] Serological survey of Rickettsia japonica infection in dogs and cats in Japan (2007)
  • Author(s): Tabuchi, M., Jilintai, Sakata, Y., Miyazaki, N., Inokuma, H.
  • Journal Title: Clin.Vac.Immunol 14(10) Pages: 1526-1528
  • Peer Reviewed
• [Journal Article] Prevelance of tick-borne Rickettsia and Ehrlichia in Ixodes persulcatus and Ixodes ovatus in Tokachi district, Eastern Hokkaido, Japan (2007)
  • Author(s): Inokuma, H., Ohashi, M., Jilintai, Tanabe, S., Miyahara, K.
  • Journal Title: J.Vet.Med.Sci 69(6) Pages: 661-664
  • Peer Reviewed
• [Journal Article] Serological survey for Ehrlichia and Anaplasma infection of feral racoons(Procyon lotor)in Kanagawa Prefecture, Japan (2007)
  • Author(s): Inokuma, H., Makino, T., Kabeya, H., Nogami, S., Fujita, H., Asano, M., Inoue, S., Maruyama, S.
  • Journal Title: Vet.Parasitol 145 Pages: 186-189
  • Peer Reviewed
• [Journal Article] Detection of Anaplasma phagocytophilum and Ehrlichia sp.HF strains in Ixodes ricinus from Brittany, France (2007)
  • Author(s): Matsumoto, K., Joncour, G., Lamanda, P., Caro, B., Le Dret, A., Inokuma, H., Brouqui, P.
  • Journal Title: Clin.Microbiol. Infect 13 Pages: 338-341
  • Peer Reviewed
• [Journal Article] Detection of Borrelia garinii, Borrelia tanukii and Borrelia sp. Closely related to Borrelia valaisiana in Ixodes ticks removed from dogs and cats in Japan (2007)
  • Author(s): Hiraoka, H., Shimada, Y., Sakata, Y., Watanabe, M., Itamoto, K., Okuda, M., Masuzawa, T., Inokuma, H.
  • Journal Title: Vet.Parasitol 144 Pages: 188-192
  • NAID: 120006390252
  • Peer Reviewed
• [Journal Article] Detection of rickettsial DNA from ticks recovered from domestic cattle in Xinjiang Uygur autonomous region area, China (2007)
  • Author(s): Chahan B., Jian Z., Jilintai, Tanabe, S., Miyahara, K., Xuan, X., Sato, Y., Moritomo, T., Nogami, S., Mikami, T., Maruyama, S., Inokuma, H.
  • Journal Title: Vet.Parasitol 144 Pages: 184-187
  • Peer Reviewed
• [Journal Article] Serological survey for Ehrlichia and Anaplasma infection of feral racoons(Procyon lotor)in Kanagawa Prefecture, Japan. (2007)
  • Author(s): Inokuma, H., Makino, T., Kabeya, H., Nogami, S., Fujita, H., Asano, M., Inoue, S., Maruyama, S.
  • Journal Title: Veterinary Parasitology 145 Pages: 186-189
  • Peer Reviewed
• [Journal Article] Comparison and phylogenetic analysis of the heat shock protein 70 gene of Babesia parasites from dogs. (2007)
  • Author(s): Yamasaki, M., Inokuma, H., Sugimoto, C., Shaw, S. E., Aktas, M., Yabsley, M. J., Yamato, O., Maede, Y.
  • Journal Title: Veterinary Parasitology 145 Pages: 217-227
  • Peer Reviewed
• [Journal Article] Development of an immunochromatographic test with recombinant BgSA1 for the diagnosis of Babesia gibsoni infection in dogs. (2007)
  • Author(s): Jia, H., Liao, M., Lee, E., Nishikawa, Y., Inokuma, H., Ikadai, H., Matsuu, A., Igarashi, I., Xuan, X.
  • Journal Title: Parasitology Research 100 Pages: 1381-1384
  • Peer Reviewed
• [Journal Article] Prevelance of tick-borne Rickettsia and Ehrlichia in Ixodes persulcatus and Ixodes ovatus in Tokachi district, Eastern Hokkaido, Japan. (2007)
  • Author(s): Inokuma, H., Ohashi, M., Jilintai, Tanabe, S., Miyahara, K.
  • Journal Title: Journal of Veterinary Medical Science 69 Pages: 661-664
  • Peer Reviewed
• [Journal Article] A dog with myelodysplastic syndrome:chronic myelomonocytic leukemia (2007)
  • Author(s): Hiraoka, H., Hisasue, M., Nagashima, N., Miyata, T., Tanimoto, T., Watanabe, M., Itamoto, K., Mizuno, T., Inokuma, H., Okuda, M.
  • Journal Title: Journal of Veterinary Medical Science 69 Pages: 665-668
  • Peer Reviewed
• [Journal Article] Serological survey of Rickettsia japonica infection in dogs and cats in Japan. (2007)
  • Author(s): Tabuchi, M., Jilintai, Sakata, Y., Miyazaki, N., Inokuma, H.
  • Journal Title: Clinical Vaccine and Immunoogy 14 Pages: 1526-1528
  • Peer Reviewed
• [Journal Article] Detection of Ehrlichia muris DNA from sika deer(Cervus nippon yesoensis)in Hokkaido, Japan. (2007)
  • Author(s): Tamamoto, C., Seino, N., Jilintai, Suzuki, M., Kaji, K., Takahashi, H., Inokuma, H.
  • Journal Title: Veterinary Parasitology 150 Pages: 370-373
  • Peer Reviewed
• [Journal Article] Pancytopenia with bleeding tendency associated with bone marrow aplasia in a Holstein calf. (2007)
  • Author(s): Shimada, A., Onozato, T., Hoshi, E., Togashi, Y., Matsui, M., Miyake, Y-I., Kobayashi, Y., Furuoka, H., Matsui, M., Sasaki, N., Ishii, M., Inokuma, H.
  • Journal Title: Journal of Veterinary Medical Science 69 Pages: 1317-1319
  • NAID: 130000447528
  • Peer Reviewed
• [Journal Article] Development of Loop-Mediated Isothermal Amplification(LAMP)method for diagnosis of equine piroplasmosis. (2007)
  • Author(s): Alhassan, A., Thekisoe, O. M., Yokoyama, N., Inoue, N., Motloang, M. Y., Mbati, P. A., Yin, H., Katayama, Y., Anzai, T., Sugimoto, C., Igarashi, I
  • Journal Title: Veterinary Parasitology 143 Pages: 155-160
  • Peer Reviewed
• [Journal Article] Comparative evaluation of the sensitivity of LAMP, PCR and In vitro culture methods for diagnosis of equine piroplasmosis. (2007)
  • Author(s): Alhassan, A., Govind, Y., Tam, N. T., Thekisoe, O. M. M., Yokoyama, N., Igarashi, I.
  • Journal Title: Parasitology Research 100 Pages: 1165-1168
  • Peer Reviewed
• [Journal Article] Cyclin-dependent kinase inhibitors block erythrocyte invasion and intraerythrocytic development of Babesiabovis in vitro. (2007)
  • Author(s): Nakamura, K., Yokoyama, N., Igarashi, I.
  • Journal Title: Parasitology 134 Pages: 1347-1353
  • Peer Reviewed
• [Journal Article] Babesia bovis:Effects of Cysteine Protease Inhibitors on In Vitro Growth (2007)
  • Author(s): Okubo, K., Yokoyama, N., Govind, Y., Alhassan, A., and Igarashi, I
  • Journal Title: Experimental Parasitology 117 Pages: 214-217
  • Peer Reviewed
• [Journal Article] Comparison of Polymerase chain reaction methods for the detection of Theileriaequi infection using whole blood compared to pre-extracted DNA samples as PCR templates. (2007)
  • Author(s): Alhassan, A., Iseki, H., Kim, C., Yokoyama, N., Igarashi, I
  • Journal Title: Tropical Animal Health and Production 39 Pages: 369-374
  • Peer Reviewed
• [Journal Article] Development of two immunochromatographic tests for the serodiagnosis of bovine babesiosis. (2007)
  • Author(s): Kim, C., Alhassan, A., Verdida, R. A., Yokoyama, N., Xuan, X., Fujisaki, K., Kawazu, S, Igarashi, I.
  • Journal Title: Veterinary Parasitology 148 Pages: 137-143
  • Peer Reviewed
• [Journal Article] Development of Taqman-based real-time PCR assays for diagnostic detection of Babesia bovis and babesia bigemina. (2007)
  • Author(s): Kim, C., Iseki, H., Maria Shiriley Herbas, Yokoyama, N., Suzuki, H., Xuan, X., Fujisaki, K., Igarashi, I.
  • Journal Title: American Journal of Tropical Medicine and Hygine 77 Pages: 837-841
  • Peer Reviewed
• [Journal Article] Asexual growth of Babesia bovis is inhibited by specific sulfated glycol-conjugates. (2007)
  • Author(s): Bork, S., Yokoyama, N., Hashiba, S., Nakamura, K., Takabatake, N., Okamura, M., Ikehara, Y., Igarashi, I.
  • Journal Title: Journal of Parasitology 93 Pages: 1501-1504
  • Peer Reviewed
• [Journal Article] Development of a multiplex loop-mediated isothermal amplification(m-LAMP)method for the simultaneous detection of bovine Babesia parasites. (2007)
  • Author(s): Iseki, H, Alhassan, A, Ohta, N., Thekisoe, O. M. M., Yokoyama, N., Inoue, N., Nambota, A., Yasuda, J., Igarashi, I
  • Journal Title: J. Microbiol. Methods, 71 Pages: 281-287
  • Peer Reviewed
• [Journal Article] Diagnostic real-time PCR assay for thequantitative detection of Theileria egui from equine blood samples. (2007)
  • Author(s): Kim, C., Blanco, L. B. C., Alhassan, A., Iseki, H., Yokoyama, N., Xuan, X., Igarashi, I.
  • Journal Title: Veterinary Parasitology 151 Pages: 158-163
  • Peer Reviewed
• [Journal Article] Detection of rickettsial DNA from ticks recovered from domestic cattle in Xinjiang Uygur autonomous region area, China. (2007)
  • Author(s): Chahan B., Jian Z., Jilintai, Tanabe, S., Miyahara, K., Xuan, X., Sato, Y., Moritomo, T., Nogami, S., Mikami, T., Maruyama, S., Inokuma, H.
  • Journal Title: Veterinary Parasitology 144 Pages: 184-187
• [Journal Article] Detection of Borrelia garinii, Borrelia tanukii and Borrelia sp. closely related to Borrelia valaisiana in Ixodes ticks removed from dogs and cats in Japan. (2007)
  • Author(s): Hiraoka, H., Shimada, Y., Sakata, Y., Watanabe, M., Itamoto, K., Okuda, M., Masuzawa, T., Inokuma, H.
  • Journal Title: Veterinary Parasitology 144 Pages: 188-192
  • NAID: 120006390252
• [Journal Article] Detection of Anaplasma phagocytophilum and Ehrlichia sp. HF strains in Ixodes ricinus from Brittany, France. (2007)
  • Author(s): Marumoto, K., Joncour, G., Lamanda, P., Caro, B., Le Dret, A., Inokuma, H., Brouqui, P.
  • Journal Title: Clinical Microbiology and Infection 13 Pages: 338-341
• [Journal Article] Epidemiological survey of Ehrlichia canis and related species infection in dogs in Sudan (2006)
  • Author(s): Inokuma, H., Oyamada, M., Davoust, B., Boni, M., Dereure, J., Bucheton, B., Hammad, A., Itamoto, K., Okuda, M., Brouqui, P.
  • Journal Title: Ann.N.Y.Acad.Sci 1078 Pages: 461-463
  • Peer Reviewed
• [Journal Article] 犬糸状虫感染症予防に来院した犬のバベシア、ヘモバルトネラおよびエールリッヒア感染状況調査 (2006)
  • Author(s): 杉村 肇、坂口真也、今村圭太、見山孝子、島田洋二郎、坂田義美、板本和仁、奥田 優、猪熊 壽
  • Journal Title: 日獣会誌 59(4) Pages: 267-270
  • Peer Reviewed
• [Journal Article] Epidemiological survey of Ehrlichia canis and related species infection in dogs in Sudan. (2006)
  • Author(s): Inokuma, H., Oyamada, M, Davoust, B, Boni, M., Dereure, J., Bucheton, B., Hammad, A., Itamoto, K., Okuda, M., Brouqui, P.
  • Journal Title: Annals of the New York Academy of Sciences 1078 Pages: 461-463
• [Journal Article] Seroepidemiological evidence for the possible presence of Babesia (Theileria) equi and Babesia caballi infection in donkeys in Western Xinjiang, China. (2006)
  • Author(s): Chahan, B., Zhang, S., Seo, J-Y.,, Nakamura, C., Zhang, G., Bannai, H., Jian, Z., Inokuma, H., Tuchiya, K., Sato, Y., Kabeya, H., Maruyama, S., Mikami, T., Xuan, X.
  • Journal Title: Journal of Veterinary Medical Science 68 Pages: 753-755
  • NAID: 130000447768
• [Journal Article] Clinical usefulness of antibodies against Babesia gibsoni detected by ELISA with recombinant P50. (2006)
  • Author(s): Miyama, T., Inokuma, H., Itamoto, K., Okuda, M., Verdida, R.A., Xuan, X.
  • Journal Title: Journal of Veterinary Medical Science 68 Pages: 1371-1373
  • NAID: 110005716386
• [Journal Article] 犬糸状虫感染症予防に来院した犬のバベシア、ヘモバルトネラおよびエールリッヒア感染状況調査. 日獣会誌. (2006)
  • Author(s): 杉村 肇, 坂口真也, 今村圭太, 見山孝子, 島田洋二郎, 坂田義美, 板本和仁, 奥田 優, 猪熊 壽
  • Journal Title: 日本獣医師会雑誌 59 Pages: 267-270
• [Journal Article] Identification of spotted fever group Rickettsia species by polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP)analysis of the Sca4 gene
  • Author(s): Matsumoto K, Inokuma H.
  • Journal Title: Vector-Borne Dis. (in press)
  • Peer Reviewed
• [Journal Article] 牛の新しい住血微生物-アナプラズマ感染症
  • Author(s): 猪熊 壽
  • Journal Title: 獣医畜産新報 (in press)
• [Presentation] 牛の住血微生物-up to date (2009)
  • Author(s): 猪熊 壽
  • Organizer: 第5回日本獣医内科学アカデミー総会
  • Place of Presentation: 東京都
  • Year and Date: 2009-02-14
• [Presentation] 北海道のタイレリア陽性牧野におけるマダニの病原微生物検索 (2009)
  • Author(s): 猪熊 壽、松山雄喜、水野大介、太田奈保美、松本高太郎、横山直明
  • Organizer: 日本産業動物獣医学会. 平成20年度日本獣医師会学会年次大会
  • Place of Presentation: 盛岡市
  • Year and Date: 2009-01-23
• [Presentation] 北海道のタイレリア陽性牧野におけるマダニの病原微生物検索 (2009)
  • Author(s): 猪熊壽、松山雄喜、水野大介、太田奈保美、松本高太郎、横山直明
  • Organizer: 平成20年度日本獣医師会学会年次大会
  • Place of Presentation: 盛岡市
  • Year and Date: 2009-01-23
• [Presentation] ダニと獣医学-マダニ媒介性感染症の多様性と動物の役割 (2008)
  • Author(s): 猪熊 壽
  • Organizer: 第63回日本衛生動物学会西日本支部大会シンポジウム
  • Place of Presentation: 神戸市
  • Year and Date: 2008-11-02
• [Presentation] Rickettsia japonica の犬に対する病原性の検討 (2008)
  • Author(s): 松田浩典、坂本礼央、竹内俊彦、吉本 薫、松山雄喜、久保田直樹、田川道人、松本高太郎、猪熊 壽
  • Organizer: 第26回日本クラミジア研究会・第15回リケッチア研究会合同研究発表会
  • Place of Presentation: 岐阜市
  • Year and Date: 2008-11-01
• [Presentation] リケッチア感染症の早期警鐘システム構築-国内実態調査及び早期診断体制の確立に向けた現状と課題 (2008)
  • Author(s): 岸本寿男、安藤秀二、猪熊 壽、岩崎博道、大橋典男、岡部信彦、川端寛樹、倉田 毅、高田信弘、堤 寛、田原研司、藤田博巳、古屋由美子、山本正悟
  • Organizer: 第26回日本クラミジア研究会・第15回リケッチア研究会合同研究発表会
  • Place of Presentation: 岐阜市
  • Year and Date: 2008-11-01
• [Presentation] Rickettsia japonicaの犬に対する病原性の検討 (2008)
  • Author(s): 松田浩典、坂本礼央、竹内俊彦、吉本薫、松山雄喜、久保田直樹、田川道人、松本高太郎、猪熊壽
  • Organizer: 第26回日本クラミジア研究会・第15回リケッチア研究会合同研究発表会
  • Place of Presentation: 岐阜市
  • Year and Date: 2008-11-01
• [Presentation] 2種の牛ヘモプラズマの病原性および感染のリスク要因としての牛白血病ウイルスとの関連性 (2008)
  • Author(s): 田川道人、松本高太郎、猪熊 壽
  • Organizer: 第146回日本獣医学会
  • Place of Presentation: 宮崎市
  • Year and Date: 2008-09-26
• [Presentation] 放牧牛からのAnaplasma phagocytophilum DNAの検出 (2008)
  • Author(s): 猪熊 壽、清野伸隆、吉林台、早川大輔、鈴木正嗣、秦 寛、近藤誠司、松本高太郎、横山直明
  • Organizer: 第146回日本獣医学会
  • Place of Presentation: 宮崎市
  • Year and Date: 2008-09-26
• [Presentation] 北海道で捕獲されたアライグマ血液からのAnaplasma bovis DNAの検出 (2008)
  • Author(s): 佐鹿万里子、阿部 豪、松本高太郎、猪熊 壽
  • Organizer: 第146回日本獣医学会
  • Place of Presentation: 宮崎市
  • Year and Date: 2008-09-26
• [Presentation] 北海道で捕獲されたアライグマ血液からのAnaplasma bovis DNAの検出 (2008)
  • Author(s): 佐鹿万里子、阿部豪、松本高太郎、猪熊壽
  • Organizer: 第146回日日本獣医学会
  • Place of Presentation: 宮崎市
  • Year and Date: 2008-09-26
• [Presentation] 潜在する人と動物のリケッチア疾患. 紅斑熱リケッチア・エーリキア・アナプラズマ (2008)
  • Author(s): 猪熊 壽
  • Organizer: 日本獣医学会ランチョンセミナー
  • Place of Presentation: 宮崎市
  • Year and Date: 2008-09-24
• [Presentation] 潜在する人と動物のリケッチア疾患. 紅斑熱リケッチア・エーリキア・アナプラズマ (2008)
  • Author(s): 猪熊壽
  • Organizer: 第146回日本獣医学会
  • Place of Presentation: 宮崎市
  • Year and Date: 2008-09-24
• [Presentation] 北海道と沖縄県の放牧牛からのAnaplasma phagocytophilum およびAnaplasma bovis DNA の検出 (2008)
  • Author(s): 猪熊 壽、吉林台、清野伸隆、早川大輔、鈴木正嗣、秦 寛、近藤誠司、松本高太郎、横山直明、大城 守、座喜味聡、松川善昌
  • Organizer: 第16回ダニと疾患のインターフェイスに関するセミナー
  • Place of Presentation: 田辺市
  • Year and Date: 2008-05-31
• [Presentation] Clinical and hematological changes in dogs experimentally inoculated with Rickettsia japonica (2008)
  • Author(s): Inokuma. H., Tagawa. M., Kubota. N., Seino, N., Murata, Y., Konishi, K.
  • Organizer: 5th International Conference on Rickettsiae and Rickettsial Diseases
  • Place of Presentation: Marseille, France
  • Year and Date: 2008-05-20
• [Presentation] Clinical and hematological changes in dogs experimentally inoculated with Rickettsia japonica (2008)
  • Author(s): Inokuma, H., Tagawa, M., Kubota, N., Seino, N., Murata, Y., Konishi, K.
  • Organizer: 5^<th> International Conference on Rickettsiae and Rickettsial Diseases
  • Place of Presentation: France
  • Year and Date: 2008-05-19
• [Presentation] ダニ-その生態と媒介微生物の多様性 (2008)
  • Author(s): 猪熊 壽
  • Organizer: 第145回日本獣医学会-公衆衛生学分科会企画シンポジウム. わが国で問題となるダニ媒介性人獣共通感染症
  • Place of Presentation: 相模原市
  • Year and Date: 2008-04-02
• [Presentation] ダニーその生態と媒介微生物の多様性 (2008)
  • Author(s): 猪熊壽
  • Organizer: 第145回日本獣医学会公衆衛生学分科会企画シンポジウム
  • Place of Presentation: 相模原市
  • Year and Date: 2008-04-02
• [Presentation] 北上・拡散するダニ媒介性疾患-犬のバベシア症の疫学と病態 (2008)
  • Author(s): 猪熊 壽
  • Organizer: 日本大学学術フロンティアシンポジウム
  • Place of Presentation: 藤沢市
  • Year and Date: 2008-03-16
• [Presentation] 北海道の放牧牛からのAnaplasma phagocytophilum およびAnaplasma bovis DNA の検出 (2008)
  • Author(s): 猪熊壽、清野伸隆、吉林台、早川大輔、鈴木正嗣、秦 寛、近藤誠司、松本高太郎、横山直明
  • Organizer: 日仏獣医学会
  • Place of Presentation: 東京
  • Year and Date: 2008-02-29
• [Presentation] 北海道の放牧牛からのAnaplasma phagocytophilumおよびAnaplasma bovis DNAの検出 (2008)
  • Author(s): 猪熊 壽, 清野伸隆, 吉林台, 早川大輔, 鈴木正嗣, 秦 寛, 近藤誠司, 松本高太郎, 横山直明
  • Organizer: 日仏獣医学会
  • Place of Presentation: 東京都下
  • Year and Date: 2008-02-29
• [Presentation] 放牧牛末梢血からのAnaplasma bovis DNA の検出 (2008)
  • Author(s): 猪熊壽、清野伸隆、吉林台、松本高太郎、早川大輔、鈴木正嗣、秦 寛、近藤誠司
  • Organizer: 日本産業動物獣医学会. 平成19年度日本獣医師会学会年次大会
  • Place of Presentation: 高松市
  • Year and Date: 2008-02-10
• [Presentation] 放牧牛末梢血からのAnaplasma bovis DNAの検出 (2008)
  • Author(s): 猪熊 壽, 清野伸隆, 吉林台, 松本高太郎, 早川大輔, 鈴木正嗣, 秦 寛, 近藤誠司.
  • Organizer: 平成19年度日本獣医師会学会年次大会日本産業動物獣医学会
  • Place of Presentation: 高松市
  • Year and Date: 2008-02-10
• [Presentation] 牛放牧地で捕獲されたエゾシカおよび放牧中の牛におけるアナプラズマおよびリケッチアの検索 (2007)
  • Author(s): 吉林台、清野伸隆、早川大輔、鈴木正嗣、秦 寛、近藤誠司、松本高太郎、猪熊 壽
  • Organizer: 第25回日本クラミジア研究会・第14回リケッチア研究会合同研究発表会
  • Place of Presentation: 東京
  • Year and Date: 2007-10-28
• [Presentation] 牛放牧地で捕獲されたエゾシカおよび放牧中の牛におけるアナプラズマおよびリケッチアの検索 (2007)
  • Author(s): 吉林台, 清野伸隆, 早川大輔, 鈴木正嗣, 秦 寛, 近藤誠司, 松本高太郎, 猪熊 壽
  • Organizer: 第25回日本クラミジア研究会・第14回リケッチア研究会合同研究発表会
  • Place of Presentation: 東京都下
  • Year and Date: 2007-10-28
• [Presentation] 牛放牧地で捕獲されたエゾシカ末梢血からのヘモプラズマおよびアナプラズマDNAの検出 (2007)
  • Author(s): 清野伸隆、田川道人、早川大輔、鈴木正嗣、秦 寛、近藤誠司、猪熊 壽
  • Organizer: 第144回日本獣医学会
  • Place of Presentation: 江別市
  • Year and Date: 2007-09-02
• [Presentation] 牛エペリスロゾーンの分子生物学的検索および系統学的位置付けの検討 (2007)
  • Author(s): 田川道人、猪熊 壽
  • Organizer: 第144回日本獣医学会
  • Place of Presentation: 江別市
  • Year and Date: 2007-09-02
• [Presentation] 獣医学領域におけるリケッチア性疾患 (2007)
  • Author(s): 猪熊 壽
  • Organizer: 第4回日本獣医内科学アカデミー総会
  • Place of Presentation: 東京
  • Year and Date: 2007-08-10
• [Presentation] Coxiella burnetii日本分離株に対するヒト血清IFA抗体価の比較 (2007)
  • Author(s): 小宮智義、鳥庭弘子、長岡宏美、福士秀人、平井克哉
  • Organizer: 第81回感染症学会総会
  • Place of Presentation: 松江市
  • Year and Date: 2007-04-17
• [Presentation] エゾシカ末梢血からのRickettsia helvetica, Anaplasma bovis および Ehrlichia muris DNAの検出 (2007)
  • Author(s): 猪熊 壽、玉本智枝、清野伸隆、田邉茂之、早川大輔、鈴木正嗣、梶光一、高橋裕史、伊吾田宏正、井上 智
  • Organizer: 第143回日本獣医学会
  • Place of Presentation: 東京
  • Year and Date: 2007-04-04
• [Presentation] エゾシカ末梢血からのRickettsia helvetica, Anaplasma bovisおよびEhrlichia muris DNAの検出. (2007)
  • Author(s): 猪熊 壽, 玉本智枝, 清野伸隆, 田邉茂之, 早川大輔, 鈴木正嗣, 梶 光一, 高橋裕史, 伊吾田宏正, 井上 智.
  • Organizer: 第143回日本獣医学会
  • Place of Presentation: つくば市
  • Year and Date: 2007-04-04
• [Presentation] 犬と猫における紅斑熱群リケッチアについての全国疫学調査 (2006)
  • Author(s): 田淵正恵、坂田義美、宮崎直美、田邉茂之、猪熊 壽
  • Organizer: 第27回動物臨床医学会
  • Place of Presentation: 大阪市
  • Year and Date: 2006-11-19
• [Presentation] エゾシカ末梢血からのリケッチアおよびエールリヒアの検出 (2006)
  • Author(s): 猪熊 壽、清野伸隆、鈴木正嗣、梶 光一、高橋裕史、井上 智
  • Organizer: 第24回日本クラミジア研究会・第13回リケッチア研究会合同研究発表会
  • Place of Presentation: 北九州市
  • Year and Date: 2006-10-21
• [Presentation] 十勝地方の公共牧場からの採取したマダニとマダニ媒介性病原体 (2006)
  • Author(s): 猪熊 壽、大橋美里、吉林台、田邊茂之、宮原和郎
  • Organizer: 平成18年度北海道地区三学会
  • Place of Presentation: 札幌市
  • Year and Date: 2006-09-07
• [Presentation] 北海道十勝地域のマダニからのリケッチアおよびエールリヒアDNAの検出 (2006)
  • Author(s): 猪熊 壽、大橋美里、吉林台、宮原和郎、田邊茂之
  • Organizer: 第58回日本衛生動物学会
  • Place of Presentation: 長崎市
  • Year and Date: 2006-04-08
• [Book] 獣医学からみたダニ起因性疾患. In : ダニと新興再興感染症(柳原保武監修、高田伸弘・馬原文彦・吉田・岸本寿男・藤田博巳編集) (2007)
  • Author(s): 猪熊壽
  • Publisher: YUKI 書房.福井
• [Book] Vectors and reservoir hosts of Anaplasmataceae. In : Rickettsial Diseases(Raoult D.&Parola P. Eds.) (2007)
  • Author(s): Inokuma, H.
  • Publisher: Taylor & Grancis Group, LLC. New York
• [Book] Vectors and reservoir hosts of Anaplasmataceae. In: Rickettsial Diseases(Raoult D. & Parola P. Eds.) (2007)
  • Author(s): Inokuma, H.
  • Total Pages: 379
  • Publisher: Taylor & Grancis Group, LLC.(New York)
• [Book] Q熱(コクシエラ症), In:人獣共通感染症(清水実嗣監修) (2007)
  • Author(s): 平井克哉
  • Total Pages: 272
  • Publisher: 養賢堂
• [Book] ダニと新興再興感染症 (2007)
  • Author(s): 柳原保武監修, 高田伸弘, 馬原文彦, 吉田, 岸本寿男, 藤田博巳編集
  • Total Pages: 296
  • Publisher: YUKI書房