Development of drugs protecting plants from environmental stress in semi-arid land
| Project/Area Number |
18380192
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Boundary agriculture
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| Research Institution | Kyoto University |
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Principal Investigator |
HIRAI Nobuhiro Kyoto University, 大学院・農学研究科, 教授 (00165151)
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| Co-Investigator(Kenkyū-buntansha) |
MIZUTANI Masaharu 京都大学, 化学研究所, 助教 (60303898)
TODOROKI Yasushi 静岡大学, 農学部, 准教授 (30324338)
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| Project Period (FY) |
2006 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
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| Budget Amount *help |
¥17,060,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥2,460,000)
Fiscal Year 2008: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2007: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2006: ¥6,400,000 (Direct Cost: ¥6,400,000)
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| Keywords | 生物環境 / 環境保全 / 植物 / 生理活性 / 有機化学 / 環境 / バイオテクノロジー |
|---|
| Research Abstract |
半乾燥地帯における植物の環境ストレス保護剤の開発を目的として、環境ストレスへの適応反応を誘導する植物ホルモン・アブシシン酸の代謝不活性化酵素に関する研究を行った。その結果、アブシシン酸水酸化酵素の選択的阻害剤の開発に成功するとともに、アブシシン酸の最終不活性化酵素であるファゼイン酸還元酵素活性の諸性質を明らかにした。これにより、アブシシン酸の不活性化制御による植物保護の道を拓いた。
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Report
(4 results)
Research Products
(32 results)
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[Journal Article] Structure-activity relationship of uniconazole, a potent inhibitor of ABA 8'-hydroxylase, with a focus on hydrophilic functional groups and conformation2008
Author(s)
Todoroki, Y., Kobayashi, K., Yoneyama, H., Hiramatsu, S., Jin, M.-H., Watanabe, B., Mizutani, M.and Hirai. N
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Journal Title
Bioorganic and Medicinal Chemistry 16
Pages: 3141-3152
NAID
Related Report
Peer Reviewed
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[Journal Article] A potent growth retardant, Uniconazole is a potent inhibitor of ABA catabolism in Arabidopsis. Bioscience2006
Author(s)
Saito, S., Okamoto, M., Shinoda, S., Kushiro, T., Koshiba, T., Kamiya, Y., Hirai, N., Todoroki, Y., Sakata, K., Nambara E. and Mizutani, M
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Journal Title
Biotechnology and Biochemistry 70
Pages: 1731-1739
Related Report
Peer Reviewed
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[Journal Article] CYP707A1 and CYP707A2, which encode ABA 8'-hydroxylase, are indispensable for a proper control of seed dormancy and germination in Arabidopsis2006
Author(s)
Okamoto, M., Kuwahara, A., Seo, M., Kushiro, T., Asami, T., Hirai, N., Kamiya, Y., Koshiba, T., and Nambara, E
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Journal Title
Plant Physiology 141
Pages: 97-107
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Peer Reviewed
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[Presentation]2008
Author(s)
白倉美奈穂, 小林亨太郎, 青山光, 平松佐織, 水谷正治, 平井伸博, 轟泰司
Organizer
植物化学調節学会第43回大会
Place of Presentation
つくばカピオ(つくば市)
Year and Date
2008-10-30
Related Report
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[Presentation] Structure-activity studies of uniconazole derivatives as strong inhibitors against ABA 8'-hydroxylase2008
Author(s)
Todoroki, Y., Yoneyama, H., Kobayashi, K,. Jin, M-H, Hirai, N. and Mizutani, M
Organizer
19th International Conference of Plant Growth Substances
Place of Presentation
Puerto Vallarta, Mexico
Year and Date
2008-07-23
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