Evaluation of human response to occupational vibration and systematic guideline for the work with hand-arm vibration exposure

• Project/Area Number: 18390181
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Hygiene
• Research Institution: Yamaguchi University
• Principal Investigator: HARADA Noriaki Yamaguchi University, 大学院・医学系研究科, 教授 (70116747)
• Co-Investigator(Kenkyū-buntansha): 井上 正岩 山口大学, 大学院医学系研究科, 助教授 (20335722) ; 横山 健治郎 山口大学, 大学院医学系研究科, 助手 (70346550)
• Co-Investigator(Renkei-kenkyūsha): HOSSAIN MD. Mahbub 山口大学, 大学院・医学系研究科, 助教 (80535336)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥17,180,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥2,580,000); Fiscal Year 2008: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2007: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000); Fiscal Year 2006: ¥6,000,000 (Direct Cost: ¥6,000,000)
• Keywords: 手腕振動 / 振動障害 / 手腕振動症候群 / 末梢循環障害 / 末梢神経障害 / 急性振動負荷 / 血流 / 振動感覚閾値

Research Abstract

上肢末梢機能を指標とする急性振動負荷実験を系統的に行ない、ISO 標準化法を主とする機能検査成績について解析した。急性振動負荷影響は環境温や振動周波数、防振手袋等で異なり、無毛部と有毛部で異なる生理学的機序が示唆された。末梢機能検査は有効であるが、病歴、理学所見、その他所見と併せて総合的に診断を行なう必要がある。関連学会・研究会、国際学術誌に発表し、体系的な曝露基準・作業基準について解析・討議を継続している。

Research Products

• [Journal Article] Acute effects of vibration on blood flow and vibrotactile perception in palmar and dorsal skin of fingers and hand among healthy subjects (2009)
  • Author(s): Mahbub MH, Hiroshige K, Tanigawa K, Kan H, Takahashi Y, Togari T, Harada N
  • Journal Title: In : Proceedings of the 17th Japan Conference on Human Response to Vibration, Tokyo, Japan (in press)
• [Journal Article] Diagnosis of vascular injuries caused by hand-transmitted vibration (2008)
  • Author(s): Harada N, Mahbub MH
  • Journal Title: Int Arch Occup Environ Health 81 Pages: 507-518
• [Journal Article] Digital blood flow and temperature responses in palmar and dorsal skin induced by short-term vibration exposure while grasping a vibratory handle (2008)
  • Author(s): Mahbub MH, Harada N
  • Journal Title: Int Arch Occup Environ Health 81 Pages: 889-897
• [Journal Article] Diagnosis of vascular injuries caused by hand -transmitted vibration (2008)
  • Author(s): Harada N
  • Journal Title: Int Arch Occup Environ Health 81 Pages: 507-518
  • Peer Reviewed
• [Journal Article] Digital blood flow and temperature res ponses in palmar and dorsalskin induced by short-term vibration exposure while grasping a vibratory handle (2008)
  • Author(s): Mahbub MH
  • Journal Title: Int Arch Occup Environ Health 81 Pages: 889-97
  • Peer Reviewed
• [Journal Article] Differences in digital vascular responses between glabrous and nonglabrous skin induced by acute exposure to hand-transmitted vibration (2007)
  • Author(s): Mahbub MH, Inoue M, Yokoyama K, Akebi T, Tanigawa K, Mizota J, Harada N
  • Journal Title: In : Bovenzi M, Peretti A, Nataletti P, Moschioni G (editors) Proceedings of the 11th International Conference on Hand-Arm Vibration, Bologna, Italy Pages: 193-200
• [Journal Article] A preliminary study on diagnostic significance of ISO standardized test methods for hand-arm vibration syndrome (2007)
  • Author(s): Harada N, Toibana N, Ishitake T, Kurozawa Y, ahbub MH, Ohmura K, Wang B
  • Journal Title: Proceedings of the 42nd UK Conference on Human Responses to Vibration, Southampton, UK Pages: 163-167
• [Journal Article] Digitalblood flow change in healthy subjects after exposure to acute hand-arm vibration, Proceedings of the 42nd UK Conference on Human Responses to Vibration (2007)
  • Author(s): Mahbub MH, Takahashi Y, Ohnari H, Akebi T, Tanigawa K, Yang G, Ohmura K, Harada N
  • Journal Title: Southampton, UK Pages: 177-183
• [Journal Article] A consideration of an evaluation index for high-level low-frequency noise by taking into account the effect of human body vibration (2007)
  • Author(s): Takahashi Y, Harada N
  • Journal Title: J Low Frequency Noise Vibration Active Control 26(1) Pages: 15-27
• [Journal Article] Assessing the influence of antivibration glove on digital vascular responses to acute hand-arm vibration (2007)
  • Author(s): Mahbub MH, Yokoyama K, Laskar MS, Inoue M, Takahashi Y, Yamamoto S, Harada N
  • Journal Title: J Occup Health 49(3) Pages: 165-171
  • NAID: 110006278710
• [Journal Article] Evaluation of the effect of heat exposure on the autonomic nervous system by heart rate variability and urinary catecholamines (2007)
  • Author(s): Yamamoto S, Iwamoto M, Inoue M, Harada N
  • Journal Title: J Occup Health 49 Pages: 199-204
  • NAID: 110006278714
• [Journal Article] Assessing the influence of antivibration glove on digital vascular responses to acute hand-arm vibration (2007)
  • Author(s): Mahbub MH
  • Journal Title: J Occup Health 49 Pages: 165-171
  • Peer Reviewed
• [Journal Article] A consideration of an evaluation index for high-level low-frequency noise by taking into account the effect of human body vibration (2007)
  • Author(s): Takahashi Y
  • Journal Title: J Low Frequency Noise Vibration Active Control 26 Pages: 15-27
  • Peer Reviewed
• [Journal Article] A preliminary study on diagnostic significance of ISO standardized test methods for hand-arm vibration syndrome (2007)
  • Author(s): Harada N
  • Journal Title: Proceedings of the 42nd UK Conference on Human Responses to Vibration, Southampton Pages: 163-167
• [Journal Article] Digital blood flow change in healthy subjects after exposure to acute hand-arm vibration (2007)
  • Author(s): Mahbub MH
  • Journal Title: Proceedings of the 42nd UK Conference on Human Responses to Vibration Pages: 177-183
• [Journal Article] Differences in digital vascular responses between glabrous and nonglabrous skin induced by acute exposure to hand-transmitted vibration (2007)
  • Author(s): Mahbub MH
  • Journal Title: Proceedings of the 11th International Conference on Hand-Arm Vibration Pages: 193-200
• [Journal Article] Effect of handle temperature on temporary threshold shift of fingertip vibration sensation induced byacute (2006)
  • Author(s): Yokoyama K, Takahashi Y, Inoue M, Laskar MS, Mahbub MH, Nakayama T, Ohnari H, Harada N
  • Journal Title: CD-ROM1 Pages: 147-152
• [Journal Article] Effects of cold-stress test using different covering methods on heart rate variability in healthy subjects (2006)
  • Author(s): Inoue M, Suizu K, Yoshimura M, Shirono S, Morita H, Kan H, Yamamoto S, Harada N
  • Journal Title: CD-ROM1 Pages: 249-254
• [Journal Article] Influence of room temperature on finger systolic blood pressure response to finger cooling in healthy (2006)
  • Author(s): Laskar MS, Ohmura K, Inoue M, Yokoyama K, Inagaki J, Takahashi Y, Mahbub MH, Ohnari, H, Harada N
  • Journal Title: CD-ROM1 Pages: 375-382
• [Journal Article] Finger blood flow responses in glabrous and nonglabrous skin induced by vibration exposure while grasping a vibratory handle (2006)
  • Author(s): Mahbub MH, Inoue M, Yokoyama K, Takahashi Y, Akebi T, Tanigawa K, Mizota J, Harada N
  • Journal Title: In : Proceedings of the 14th Japan Conference on Human Response to Vibration, Tokyo, Japan Pages: 99-109
• [Journal Article] Assessment of room temperature influence on finger blood flow response induced by short-term grasping of vibrating handle (2006)
  • Author(s): Mahbub MH, Inoue M, Yokoyama K, Laskar MS, Ohnari1 H, Suizu K, Inagaki J, Takahashi Y, Harada N
  • Journal Title: Int Arch Occup Environ Health 79 Pages: 22-26
• [Journal Article] Assessment of room temperature influence on finger blood flow response induced by short-term grasping of vibrating handle (2006)
  • Author(s): Mahbub MH
  • Journal Title: Int Arch Occup Environ Health 79 Pages: 22-26
• [Journal Article] Finger blood flow responses in glabrous and nonglabrous skin induced by vibration exposure while grasping a vibratory handle (2006)
  • Author(s): MH Mahbub
  • Journal Title: 14^th Japan Conference on Human Response to Vibration Pages: 99-109
• [Journal Article] Effect of Handle Temperature on Temporary Threshold Shift of Fingertip Vibration Sensation Induced by Acute Vibration Exposure (2006)
  • Author(s): K Yokoyama
  • Journal Title: Proceedings of 10^th Conference on Hand-arm Vibration CD Pages: 147-152
• [Journal Article] Effects of Cold-Stress Test Different Covering Methods on Heart Rate Variability in Healthy Subjects (2006)
  • Author(s): M Inoue
  • Journal Title: Proceedings of 10^th Conference on Hand-arm Vibration CD Pages: 249-254
• [Journal Article] Influence of Room Temperature on Finger Systolic Blood Pressure Response to Finger Cooling in Healthy Vibration Sensation Induced by Acute Vibration Exposure (2006)
  • Author(s): MS Laskar
  • Journal Title: Proceedings of 10^th Conference on Hand-arm Vibration CD Pages: 375-382
• [Journal Article] Diagnosis of vascular injuries caused by hand-transmitted vibration (2006)
  • Author(s): N Harada
  • Journal Title: Diagnosis of injuries caused by hand-transmitted vibration - 2nd International workshop Pages: 30-31
• [Presentation] Digital blood flow change in healthy subjects after exposure to acute hand-arm vibration (2007)
  • Author(s): Mahbub MH, Takahashi Y, Ohnari H, Akebi T, Tanigawa K, Yang G, Ohmura K, Harada N
  • Organizer: 42nd UK Conference on Human Responses to Vibration
  • Place of Presentation: Southampton, UK
  • Year and Date: 2007-09-11
• [Presentation] A preliminary study on diagnostic significance of ISO standardized test methods for hand-arm vibration syndrome (2007)
  • Author(s): Harada N
  • Organizer: 42nd UK Conference on Human Responses to Vibration
  • Place of Presentation: Southampton,UK
  • Year and Date: 2007-09-11
• [Presentation] Digital blood flow change in healthy subjects after exposure to acute hand-arm (2007)
  • Author(s): Mahbub MH
  • Organizer: 42nd UK Conference on Human Responses to Vibration
  • Place of Presentation: Southampton,UK
  • Year and Date: 2007-09-11
• [Presentation] Differences in digital vascular responses between glabrous and nonglabrous skin induced by acute exposure to hand-transmitted vibration (2007)
  • Author(s): Mahbub MH
  • Organizer: 11th International Conference on Hand-Arm Vibration
  • Place of Presentation: Bologna,Italy
  • Year and Date: 2007-06-05
• [Presentation] 手腕振動障害における末梢循環異常の定量化産業衛生学雑誌、49増刊 (2007)
  • Author(s): Mahbub MH、大村佳代、井上正岩、原田規章
  • Organizer: 日本衛生学会総会
  • Place of Presentation: 大阪(397)
  • Year and Date: 2007-04-26
• [Presentation] 手腕振動障害における末梢循環異常の定量化 (2007)
  • Author(s): Mahbub MH
  • Organizer: 日本産業衛生学会
  • Place of Presentation: 大阪
  • Year and Date: 2007-04-26
• [Presentation] A preliminary study on diagnostic significance of ISO standardizedtest methods for hand-arm vibration syndrome (2007)
  • Author(s): Harada N, Toibana N, Ishitake T, Kurozawa Y, Mahbub MH, Ohmura K, Wang B
  • Organizer: 42nd UK Conference on Human Responses to Vibration
  • Place of Presentation: Southampton, UK
• [Presentation] Differences in digital vascular responses between glabrous and nonglabrous skin induced by acute exposure to hand-transmitted (2007)
  • Author(s): Mahbub MH, Inoue M, Yokoyama K, Akebi T, Tanigawa K, Mizota J, Harada N
  • Organizer: 11th International Conference on Hand-Arm Vibration
  • Place of Presentation: Bologna, Italy
• [Presentation] Evaluation of vibrotactile perception thresholds among patients with hand-arm vibration syndrome : A preliminary report, 日本衛生学雑誌 (2007)
  • Author(s): Wang B, Kuroki K, Mahbub MH, Ohmura K, Harada N
  • Organizer: 日本衛生学会総会
  • Place of Presentation: 大阪(62 : 2, 720)
• [Presentation] 加振ハンドル把持時における防振手袋使用が末梢循環反応に及ぼす影響、産業衛生学雑誌、48増刊 (2006)
  • Author(s): Mahbub MH、横山健治郎、Laskar MS、井上正岩、高橋幸雄、原田規章
  • Organizer: 日本産業衛生学会総会
  • Place of Presentation: 仙台, (372)
  • Year and Date: 2006-05-10
• [Presentation] 手腕振動曝露が及ぼす末梢循環反応におけるハンドル表面温度影響の検討、産業衛生学雑誌、48増刊 (2006)
  • Author(s): 井上正岩、横山健治郎、Laskar MS、Mahbub MH、山本真二、涌井忠昭、原田規章
  • Organizer: 日本産業衛生学会総会
  • Place of Presentation: 仙台(373)
  • Year and Date: 2006-05-10
• [Presentation] 手腕振動症候群診断のための冷却負荷手指血圧検査における冷却用ブランケット使用の影響、産業衛生学雑誌、48増刊 (2006)
  • Author(s): Laskar MS、Mahbub MH、井上正岩、横山健治郎、大村佳代、原田規章
  • Organizer: 日本産業衛生学会総会
  • Place of Presentation: 仙台(375)
  • Year and Date: 2006-05-10
• [Presentation] A consideration of an evaluation index for high-level low-frequency noise by taking into account the effect of human body vibration (2006)
  • Author(s): Takahashi Y, Harada N
  • Organizer: 12th International Meeting on Low Frequency Noise and Vibration and its Control
  • Place of Presentation: Bristol, UK
• [Presentation] Diagnosis of vascular injuries caused by hand-transmitted vibration, Diagnosis of injuries caused by hand-transmitted vibration- (2006)
  • Author(s): Harada N
  • Organizer: 2nd International workshop
  • Place of Presentation: Gothenburg
• [Presentation] Finger blood flow responses in glabrous and nonglabrous skin induced by vibration exposure while grasping a vibratory handle (2006)
  • Author(s): Mahbub MH, Inoue M, Yokoyama K, Takahashi Y, Akebi T, Tanigawa K, Mizota J, Harada N
  • Organizer: 14th Japan Conference on Human Response to Vibration
  • Place of Presentation: Tokyo, Japan