Development of an four-dimensional image-guided radiotherapy system
Project/Area Number |
18390333
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Radiation science
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Research Institution | Kyoto University |
Principal Investigator |
NAGATA Yasushi Kyoto University, 医学研究科, Associate Professor (10228033)
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Co-Investigator(Kenkyū-buntansha) |
MITSUMORI Michihide Kyoto University, 医学研究科, Lecturer (10263089)
MIZOWAKI Takashi Kyoto University, 医学研究科, Lecturer (90314210)
NARITA Yuichiro Kyoto University, 医学研究科, Lecturer (30311385)
|
Project Period (FY) |
2006 – 2007
|
Project Status |
Completed (Fiscal Year 2007)
|
Budget Amount *help |
¥13,310,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2007: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2006: ¥7,200,000 (Direct Cost: ¥7,200,000)
|
Keywords | 4-dimensional treatment planning / radiotherapy / IGRT / respiratory gating / 4-d CT / stereotactic radiotherapy |
Research Abstract |
To develop a new four-dimensional image-guided radiotherapy (IGRT) system, the following systems were developed. 1. Four-dimensional treatment planning system Four-dimensionally reconstructed CT images were obtained using MD-CT and gating signals. With these images, the movement of lung tumor could be more precisely evaluated. 2. Respiratory gating system The relationship between the abdominal wall movement of a patient and lung tumor movement was evaluated. As a result, the correlation was so high (0.97). Therefore, the abdominal wall movement can be used as a surrogate signal for lung tumor. 3. Clinical application of SBRT Two-hundreds and thirty patients have been treated with SBRT technique. Ninety percent of high local control rates had been achieved for the patients with T1NOMO and T2NOMO tumor. Serious complications greater than CTCAE Grade 3 were 1.5%. The clinical results for the patients with pulmonary oligometastases were also promising. 4. Development of an IGRT system A new four-dimensional IGRT system was equipped with gimbaled X-ray system and ultralight C-band linear accelerator on a rigid 0-ring structure. The accuracy of the static beam positioning was 0.1mm.
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Report
(3 results)
Research Products
(96 results)
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[Journal Article] Interinstitutional variations in planning for stereotactic body radiation therapy for lung cancer2007
Author(s)
Matsuo, Y., Takayama, K., Nagata, Y., Kunieda, E., Tateoka, K., Ishizuka, N., Mizowaki, T., Norihisa, Y., Sakamoto, M., et. al.
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Journal Title
J. Radiat. Oncol. Biol. Phys Vol.68
Pages: 416-425
Description
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[Journal Article] Impact of optimization algorithms on the intensity map in IMRt treatment planning2007
Author(s)
Shimada, M., Nakamura, M., Miyabe, Y., Yamamoto, T., Teshima, T., Narita, Y., Mizowaki, N., Nagata, Y., Hiraoka, H
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Journal Title
Jp. J. Med. Phys Vol.26
Pages: 97-106
NAID
Description
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[Journal Article] Development of a four-dimensional image-guided radiotherapy system with a gimballed x-ray head2006
Author(s)
Kamino, Y., Takayama, K., Kokubo, M., Narita, Y., Hirai, E., Nagata, Y., et. al.
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Journal Title
Int. J. Radiation Oncology Biol. Phys Vol.66
Pages: 271-278
Description
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[Journal Article] Characteristics of patients who developed radiation pneumonitis requiring steroid therapy after stereotactic irradiation for lung tumors2006
Author(s)
Fujino, M., Shirato, H., Onishi, H., Kawamura, H., Takayama, K., Koto, M., Onimaru, R., Nagata, Y., Hiraoka M
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Journal Title
The Cancer Journal Vol.12
Pages: 41-46
Description
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[Presentation] 高精度放射線治療2008
Author(s)
永田 靖
Organizer
第6回日本臨床腫瘍学会 教育講演
Place of Presentation
福岡
Year and Date
2008-03-21
Description
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[Presentation] 体幹部定位照射の現況2008
Author(s)
永田 靖
Organizer
第190回広島県放射線医会 特別講演
Place of Presentation
広島
Year and Date
2008-01-25
Description
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[Presentation] 体幹部定位照射の現況2008
Author(s)
永田 靖
Organizer
宇治・久世医師会講演会
Place of Presentation
京都
Year and Date
2008-01-17
Description
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[Presentation] 高精度放射線治療2007
Author(s)
Nagata Y, et. al
Organizer
日中医学交流
Place of Presentation
東京
Year and Date
2007-12-07
Description
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[Presentation] 体幹部定位照射の現況2007
Author(s)
永田 靖
Organizer
第1回沖縄放射線治療研究会
Place of Presentation
那覇
Year and Date
2007-11-30
Description
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[Presentation] 高精度放射線治療2007
Author(s)
永田 靖
Organizer
第45回日本癌治療学会 教育セッション
Place of Presentation
京都
Year and Date
2007-10-25
Description
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[Presentation] 体幹部定位照射の現況2007
Author(s)
永田 靖
Organizer
東京大学先端医療セミナー
Place of Presentation
東京
Year and Date
2007-10-05
Description
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[Presentation] A Phase II study of accelerated high dose thoracic irradiation with concurrent chemoradiotherapy for patients with LD SCLC as a common arm trial of the US trial. (JMTO LC 04-01 : RTOG-0239)2007
Author(s)
Nagata, Y., Takayama, K., Matsuo, Y., Norihisa, Y., MIzowaki, T., Hiraoka, M
Organizer
JMTO seminar
Place of Presentation
Karuizawa, JAPAN
Year and Date
2007-09-08
Description
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[Presentation] Survey of SBRT in Japan2007
Author(s)
Nagata, Y., Takayama, K., Matsuo, Y., Norihisa, Y., MIzowaki, T., Hiraoka, M
Organizer
JUCTS seminar
Place of Presentation
Sendai, JAPAN
Year and Date
2007-09-07
Description
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[Presentation] 乳癌と肺癌に対する放射線治療2007
Author(s)
永田 靖
Organizer
第18回日本放射線科専門医講習会
Place of Presentation
東京
Year and Date
2007-07-03
Description
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[Presentation] 体幹部定位照射の現況2007
Author(s)
永田 靖
Organizer
第7回月輪呼吸器疾患研究会
Place of Presentation
大津
Year and Date
2007-02-16
Description
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[Presentation] 高精度放射線治療2006
Author(s)
永田 靖
Organizer
第19回日本放射線腫瘍学会 教育講演
Place of Presentation
仙台
Year and Date
2006-11-25
Description
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[Presentation] 体幹部定位放射線治療2006
Author(s)
永田 靖
Organizer
第44回日本癌治療学会シンポジウム
Place of Presentation
東京
Year and Date
2006-10-18
Description
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[Presentation] 体幹部定位照射の現況2006
Author(s)
永田 靖
Organizer
関西Radiology Update研究会
Place of Presentation
大阪
Year and Date
2006-09-30
Description
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[Presentation] 体幹部定位照射の現状2006
Author(s)
永田 靖
Organizer
第35回鹿児島放射線治療研究会
Place of Presentation
鹿児島
Year and Date
2006-07-07
Description
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[Presentation] 乳癌と肺癌に対する放射線治療2006
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永田 靖
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第17回日本放射線科専門医講習会
Place of Presentation
東京
Year and Date
2006-07-04
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