| Project/Area Number |
18390340
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General surgery
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| Research Institution | Akita University |
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Principal Investigator |
KATAYOSE Yoshihisa Akita University, School of Medicine, Lecturer (40282165)
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| Co-Investigator(Kenkyū-buntansha) |
OGAWA Jun-ichi Akita University, School of Medicine, Professor (20112774)
MINAMIYA Yoshihiro Akita University, School of Medicine, Associate professor (30239321)
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| Project Period (FY) |
2006 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥16,070,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥1,770,000)
Fiscal Year 2007: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
Fiscal Year 2006: ¥8,400,000 (Direct Cost: ¥8,400,000)
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| Keywords | Breast cancer / maenetic force / sentinel / metastasis / 磁性体 / センチネルリンパ節 |
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| Research Abstract |
We succeeded in making a small magnetic sound sensor with diameter of 11 mm and a length of 12 cm. The sensitivity of this sensor was investigated using a false lymphaden subjected to a 300-microl injection of a magnetic fluid 50 nm in diameter. The sound of the double cycle of a magnetization cycle was intentionally observed to around 100Hz. The sensitivity of this improved sensor was fifty times higher than that of the initial one. The site at which sonic waves generated after being magnetized can be detected is limited right above a false lymphaden. The directivity of the sensor is very useful for detecting sentinel nodes.
Our next goal is visualization of sentinel lymph nodes using this magnetic sound sensor in a way similar to ultrasound. Such visualization aids the surgeon during excisional biopsy of sentinel lymph node.
A further goal is to subject metastatic lymph nodes to hyperthermia using magnetite.
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