Development and clinical application of cDNA microarray using formalin fixed paraffin embedded specimen
| Project/Area Number |
18390362
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Digestive surgery
|
|---|
| Research Institution | Tokyo Medical and Dental University |
|---|
Principal Investigator |
UETAKA Hiroyuki (UETAKE Hiroyuki) Tokyo Medical and Dental University, 医歯学総合研究科, 寄附講座教員 (60311651)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
SUGIHARA Kenichi 東京医科歯科大学, 医歯学総合研究科, 教授 (10171167)
HIGUCHI Teturo 東京医科歯科大学, 医歯学総合研究科, 助教 (90334416)
IIDA Satoshi 東京医科歯科大学, 医歯学総合研究科, 助教 (20361694)
ISHIKAWA Tosiaki 東京医科歯科大学, 医歯学総合研究科, 寄附講座教員 (00422478)
|
|---|
| Project Period (FY) |
2006 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥15,780,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥1,980,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2008: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2007: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2006: ¥7,200,000 (Direct Cost: ¥7,200,000)
|
|---|
| Keywords | 大腸小腸肛門外科学 / パラフィン包埋標本 / マイクロアレイ / RT-PCR / 遺伝子発現 / リアルタイムPCR / 予後因子 / 抗癌剤感受性 / 化学療法 |
|---|
| Research Abstract |
Microarray technology is potentially a powerful approach to identify genes expression signatures that predict the effects of chemotherapeutic drugs. The aim of this study is to develop cDNA microarray using RNA isolated from laser-capture microdisssected formalin fixed paraffin embedded (FFPE) specimens.
|
Report
(6 results)
Research Products
(60 results)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] Danenberg^1Molecular Signatures of Gastric Cancers Derived from Microarray Analysis of Paraffin-Embedded Specimens Predict the Degree of Response to CPT11/S-1 Chemotherapy2008
Author(s)
Shinji Morita, Mikito Inokuchi, Hiroyuki Uetake, Andreas C. Hoffmann, Janine Cooc, Akiko Omori, Kenichi Sugihara, Kathleen D. Danenberg, Peter V.
Organizer
The annual meeting of ASCO
Place of Presentation
Chicago, IL, USA
Year and Date
2008-06-01
Related Report
-
-
-
-
-
-
-
-
-
-
-
-
-
