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Study on the neural mechanism that supports the functional recovery of aphasia by using optical topography.

Research Project

Project/Area Number 18390404
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Cerebral neurosurgery
Research InstitutionJichi Medical University

Principal Investigator

WATANABE Eiju  Jichi Medical University, 医学部, 教授 (50150272)

Co-Investigator(Kenkyū-buntansha) DAN Ippeita  独立行政法人農業・食品産業技術総合研究機構食品総合研究所, 食品機能研究領域, 主任研究員 (20399380)
Project Period (FY) 2006 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥17,040,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥2,640,000)
Fiscal Year 2008: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2007: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2006: ¥5,600,000 (Direct Cost: ¥5,600,000)
Keywords光トポグラフィ / 失語症 / リハビリテーション / 機能回復 / 脳機能計測 / 言語野 / シュミレーションMRI / 光トポグラフィー / 言語機能計測 / MRI脳表画像 / 3次元位置計測 / 高次脳機能 / シュミレーション / MRI / シミュレーション
Research Abstract

失語症の30%は劣位半球に言語活動がみられた。追跡を行った11名中7例は半年後には劣位側の活性が優位側に移行。回復早期には劣位側が言語をささえ、その後優位側に移行する現象が認められた。バーチャル・レジストレーション法の推定精度は約1cm以内でMRI3次元デジタイザーなしでも脳回レベルの空間解析は可能であると考えられた。この標準脳座標系により被験者間のデータの比較や他の計測法データとの統合も可能となった。

Report

(4 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (20 results)

All 2009 2008 2007 2006

All Journal Article (10 results) (of which Peer Reviewed: 4 results) Presentation (10 results)

  • [Journal Article] Structural atlas-based spatial registration for functional near-infrared. spectroscopy enabling inter-study data integration.2009

    • Author(s)
      Masako Okamoto, Daisuke Tsuzuk, Lester Clowney, Haruka Dan, Archana Singh, Ippeita Dan
    • Journal Title

      Clinical Neurophysiology In press

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Activation in ventro-lateral prefrontal cortex during the act of tasting: an fNIRS study.2009

    • Author(s)
      Masako Okamoto, Haruka Dan, Lester Clowney, Yui Yamaguchi, Ippeita Dan
    • Journal Title

      Neroscience Latters 451

      Pages: 129-133

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Scope of Resampling-based methods in functional neuroimaging analysis with small multiplicity issue2009

    • Author(s)
      Archna K. Singh, Lester Clowney, Masako Okamoto, James B. Cole, Ippeita Dan
    • Journal Title

      Statistical Sinica. 18

      Pages: 1519-1534

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 高次機能障害の画像診断。6.光トポグラフィーによる高次機能の計測2008

    • Author(s)
      小黒恵司, 横田英典, 渡辺英寿
    • Journal Title

      神経内科 68

      Pages: 70-81

    • Related Report
      2008 Final Research Report
  • [Journal Article] 光トポグラフィーによる非侵襲的言語機能の計測2008

    • Author(s)
      小黒恵司, 横田英典, 渡辺英寿
    • Journal Title

      臨床脳波 50

      Pages: 110-117

    • Related Report
      2008 Final Research Report
  • [Journal Article] 近赤外線光トポグラフィによる脳機能計測2007

    • Author(s)
      渡辺 英寿
    • Journal Title

      脳21 10巻3号

      Pages: 81-86

    • NAID

      10013113451

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 光トポグラフィデータの空間的レジストレーション2007

    • Author(s)
      檀 一平太
    • Journal Title

      認知神経科学 9巻1号

      Pages: 13-18

    • NAID

      130004388072

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 近赤外光を用いた脳機能解析法2007

    • Author(s)
      檀 一平太
    • Journal Title

      ぶんせき 6

      Pages: 276-283

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Virtual spatial registration of stand-alone functional NIRS data to MNI space.2007

    • Author(s)
      Tsuzuki, D., Jurcak, V., Singh, A.K., Okamoto, M., Watanabe, E., Dan, I
    • Journal Title

      NeuroImage 34

      Pages: 1506-1518

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 失語の近赤外線光トポグラフィー2006

    • Author(s)
      渡辺英寿
    • Journal Title

      CLINICAL NEUROSCIENCE,(7) :,2006 24

      Pages: 763-766

    • Related Report
      2006 Annual Research Report
  • [Presentation] NIRSの脳神経外科分野における応用2008

    • Author(s)
      渡辺英寿
    • Organizer
      第10回日本光脳機能イメージング研究会
    • Place of Presentation
      大阪
    • Year and Date
      2008-12-13
    • Related Report
      2008 Final Research Report
  • [Presentation] Probabilistic spatial registration of fNIRS data with crossmodal perspective.2008

    • Author(s)
      Ippeita Dan
    • Organizer
      13th Annual Meeting of Pacific Rim College of Psychiatrists.
    • Place of Presentation
      東京
    • Year and Date
      2008-10-30
    • Related Report
      2008 Final Research Report
  • [Presentation] Resampling fNIRS time series in wavelet domain2008

    • Author(s)
      Archana K. Singh, Masako Okamoto, Lester Clowney, James B. Cole, Ippeita Dan
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      東京
    • Year and Date
      2008-07-11
    • Related Report
      2008 Final Research Report
  • [Presentation] Resampling fNIRS time series in wavelet domain2008

    • Author(s)
      Archana K. Singh, Masako Okamoto, Lester Clowney, James B. Cole, Ippeita Dan
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-11
    • Related Report
      2008 Annual Research Report
  • [Presentation] Bayesian Statistics, Frequentist Statistics and fNIRS2008

    • Author(s)
      Lester Clowney, Masako Okamoto, Archana K. Singh, Ippeita Dan
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      東京
    • Year and Date
      2008-07-10
    • Related Report
      2008 Final Research Report
  • [Presentation] Prefrontal involvement in taste recognition :fNIRS study2008

    • Author(s)
      Masako Okamoto, Yuji Wada, Daisuke Tsuzuki, Lester Clowney, Archana K. Singh , Ippeita Dan
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      東京
    • Year and Date
      2008-07-09
    • Related Report
      2008 Final Research Report
  • [Presentation] Prefrontal involvement in taste recognition : fNIRS study2008

    • Author(s)
      Masako Okamoto, Yuji Wada, Daisuke Tsuzuki, Lester Clowney, Archana K. Singh, Ippeita Dan
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] New diagnostic method for epilepsy focus using near infrared Spectroscopy.2008

    • Author(s)
      Eiju Watanabe
    • Organizer
      The 33rd Annual Meeting of The Egyptian Society of Neurological Surgeons
    • Place of Presentation
      エジプト
    • Year and Date
      2008-02-28
    • Related Report
      2008 Final Research Report
  • [Presentation] 光で見る脳の高次機能-失語症から認知症まで2008

    • Author(s)
      渡辺英寿
    • Organizer
      第22回脳神経市民公開講座
    • Place of Presentation
      名古屋
    • Year and Date
      2008-01-06
    • Related Report
      2008 Final Research Report
  • [Presentation] f NIRSにおける高次脳機能計測の臨床応用2007

    • Author(s)
      渡辺 英寿
    • Organizer
      第48回日本脈絡学会総会
    • Place of Presentation
      松本
    • Year and Date
      2007-10-27
    • Related Report
      2007 Annual Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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