• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Effects of plant-derived protease on removing tongue coatings and reducing volatile sulphur compounds in oral air

Research Project

Project/Area Number 18390565
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Social dentistry
Research InstitutionNiigata University

Principal Investigator

MIYAZAKI Hideo  Niigata University, 医歯学系, 教授 (00157629)

Co-Investigator(Kenkyū-buntansha) YAMAGA Takayuki  新潟大学, 医歯学総合病院, 助教 (90345512)
KANEKO Noboru  新潟大学, 医歯学系, 助教 (00397126)
NOHNO Kaname  新潟大学, 医歯学系, 助教 (80422608)
Project Period (FY) 2006 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥8,180,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2007: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2006: ¥2,200,000 (Direct Cost: ¥2,200,000)
Keywords舌苔 / プロテアーゼ / 口臭 / 介入研究 / 舌苔細菌 / 無作為化対照試験
Research Abstract

口臭の主な原因は舌苔(舌の上にある苔状の組織)から生ずる気体である.そのため舌苔を除去することで口臭が抑制される.本研究では植物由来のタンパク分解酵素アクチニジンによりタンパク質を多く含む舌苔が分解・除去され、口臭が減少することを検討した.結果として、アクチニジンは口の中の細菌に影響を与えることなく舌苔の量を減少させ、それに伴って口臭を減少させることが確認された.

Report

(4 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (9 results)

All 2008 2007 2006 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (6 results) Remarks (2 results)

  • [Journal Article] プロテアーゼ含有タブレットの口臭抑制効果2007

    • Author(s)
      吉松大介, 杉村真司, 井岡俊之, 白石浩荘, 米谷俊, 山賀孝之, 宮崎秀夫
    • Journal Title

      口腔衛生会誌 57

      Pages: 22-27

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Presentation] Products for breath odor control2008

    • Author(s)
      H. MIYAZAKI
    • Organizer
      5th Conference of Asian Society for Breath Odor Research
    • Place of Presentation
      バンコク(タイ)
    • Year and Date
      2008-05-06
    • Related Report
      2008 Final Research Report
  • [Presentation] アクチニジンタブレット長期服用による口臭抑制効果2008

    • Author(s)
      濃野要
    • Organizer
      第57回日本口腔衛生学会・総会
    • Place of Presentation
      さいたま(埼玉)
    • Related Report
      2008 Final Research Report
  • [Presentation] アクチニジンタブレツト長期服用による口臭抑制効果2008

    • Author(s)
      濃野 要, 他
    • Organizer
      第57回日本口腔衛生学会・総会
    • Place of Presentation
      大宮, 埼玉
    • Related Report
      2008 Annual Research Report
  • [Presentation] Cysteine protease reduces tongue coating and volatile sulfur compounds2007

    • Author(s)
      K. NOHNO
    • Organizer
      第85回International Association for Dental Research(IADR)総会
    • Place of Presentation
      ニューオーリンズ(アメリカ)
    • Related Report
      2008 Final Research Report
  • [Presentation] Biochemical tongue cleaning for disabled elderly people2007

    • Author(s)
      Daisuke Yoshimatsu
    • Organizer
      7th International Conference for Breath Odor
    • Place of Presentation
      Chicago, USA
    • Related Report
      2007 Annual Research Report
  • [Presentation] Effects of protease extracted from a plant on reduction of both tongue coating and VSCs2006

    • Author(s)
      H. MIYAZAKI
    • Organizer
      The 3rd Conference of Asian Association for Breath Odor Research (ASBOR)
    • Place of Presentation
      岡山(岡山)
    • Year and Date
      2006-11-28
    • Related Report
      2008 Final Research Report
  • [Remarks] 濃野要, 宮崎秀夫, 山賀孝之 : Clinical Report/プロテアーゼを用いた口臭ケア・舌苔ケアのアプローチ, Dental Magazine, 125 : 50-53, 2008.

    • Related Report
      2008 Final Research Report
  • [Remarks] 宮崎秀夫 : TRENDS, プロテアーゼによる舌苔除去・口臭予防, Dental Magazine, 122 : 62-66, 2007.

    • Related Report
      2008 Final Research Report

URL: 

Published: 2006-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi