Immuno-genetics on Mongoloid in Pan-Pacific and Northland Areas

• Project/Area Number: 18406006
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 海外学術
• Research Field: Human genetics
• Research Institution: Aichi Cancer Center Research Institute
• Principal Investigator: TAJIMA Kazuo Aichi Cancer Center Research Institute, 愛知県がんセンター(研究所), Director (30150212)
• Co-Investigator(Kenkyū-buntansha): HIRAKI Akio Aichi Cancer Center Research Institute, Division of Epidemiology and Prevention, Section Head (70443455) ; MATSUO Keitaro Aichi Cancer Center Research Institute, Division of Epidemiology and Prevention, Senior Researcher (80393122) ; CHIBA Hitoshi Hokkaido University, School of Medicine, Professor (70197622) ; SENOO Haruki Akita University, 副学長 (90171355)
• Project Period (FY): 2006 – 2007
• Project Status: Completed (Fiscal Year 2007)
• Budget Amount: ¥14,760,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥1,860,000); Fiscal Year 2007: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000); Fiscal Year 2006: ¥6,700,000 (Direct Cost: ¥6,700,000)
• Keywords: Ethnoepidemiology / Mongoloid / HTLV-I / HLA / Fat metabolism / 民族疾学 / イヌイット族 / HBV

Research Abstract

To contribute to the establishment of comprehensive information on worldwide Mongoloid dispersal, we have studied ethnoepidemiologic features of tumour viruses and immuno-genetic characteristics among Mongoloids during the last twenty years. To analyze geographic and ethnic distribution of HTLV-1and genetic polymorphism patterns of human leucocyte antigen (HLA) and fat metabolites among Mongoloid people in Northland areas in the present study, we focused on 200 Inuit people in North Canada and East Greenland (Denmark). We projected field works in winter season (January of February) when indigenous people settle down in one place according to the mentioned above purposes. In 2006 we planned a field work on Inuit people in Yukon area, North Canada in collaboration with University of Vancouver, but we finally could not get official permission of collecting blood samples from indigenous people from the authority of British Columbian Government. Instead of it, we invested HLA subtypes (DR, DP, DQ) frequency among 600 Japanese people in Aichi Prefecture to compare characteristic distribution among worldwide Mongoloids people. In 2007 we focused on Inuit people in East Greenland, Denmark and conducted a field work to collect blood samples from 100-200 people in Ittoqqortoormiit, but we had to obliged giving up collecting blood samples because of order to stop from the Greenland authority. Nowadays we are negotiating collaboration with Danish researchers who have collected blood samples from Inuit people in the same area during the last several years. On the other hand we have established lymphocytes bank (Sonoda-Tajima Collection) of worldwide Mongoloid people which we collected during the last 20 years linked with the present study, at the Bio-resource Center, RIKEN Institute for multipurpose usage of those valuable materials. We put together comprehensive information on worldwide distribution of HTLV-I among Mongoloids and their immuno-genetic characteristics.

Research Products

• [Journal Article] Quantification of lamivudine-resistant hepatitis B virus mutants by type-specific TaqMan minor groove binder probe assay in patients with chronic hepatitis B (2008)
  • Author(s): Yoshida S
  • Journal Title: Ann Clin Biochem 45 Pages: 59-64
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2D (2008)
  • Author(s): Takada A
  • Journal Title: J Immunol 180 Pages: 1678-1685
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Reduced apolipoprotein E-rich high-density liproprotein level at birth is restored to the normal range in patients with familial hypercholestero-lemia in the first year of life (2008)
  • Author(s): Nagasaka H
  • Journal Title: J Clin Endocrinol Metab 93 Pages: 779-783
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Decreased risk of colorectal cancer with the high Natural-Killer (NK)-cell activity NKG2D genotype in Japanese (2008)
  • Author(s): Furue H
  • Journal Title: Carcinogenesis 29(2) Pages: 316-320
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Opposite impact of NKG2D genotype by lifestyle exposure to risk of Aerodigestive tract cancer among Japanese (2008)
  • Author(s): Furue H
  • Journal Title: Int J Cancer 123 Pages: 181-186
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Decreased risk of colorectal cancer with the high Natural-Killer (NK)-cell activity NKG2D genotype in Japanese. (2008)
  • Author(s): Furue H, Matsuo K. Kumimoto H, Hiraki A. Suzuki T, Yatabe Y, Komori K, Kanemitsu Y, Hirai T, Kato T, Ueda M, Ishizaki K, Tajima K
  • Journal Title: Carcinogenesis 29 Pages: 316-320
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Opposite Impact of NKG2D Genotype by Lifestyle Exposure to Risk of Aerodigestive Tract Cancer among Japanese. (2008)
  • Author(s): Furue H, Kumimoto H, Matsuo K. Suzuki T, Hasegawa Y, Shinoda M, Mitsudo K, Tohnai I, Ueda M, Tajima K., Ishizaki K.
  • Journal Title: Int J Cancer 123 Pages: 181-186
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Reduced Apolipoprotein E-Rich High-Density Lipoprotein Level at Birth Is Restored to the Normal Range in Patients with Familial Hypercholesterolemia in the First Year of Life. (2008)
  • Author(s): Nagasaka H, Miida T, Hirano K, Ota A, Yorifuji T, Takatani T, Tsukahara H, Takayanagi M, Hui SP, Kobayashi K, Chiba H
  • Journal Title: J Clin Endocrinol Metab 93 Pages: 779-783
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2D. (2008)
  • Author(s): Takada A, Yoshida S, Kajikawa M, Miyatake Y, Tomaru U, Sakai M, Chiba H. Maenaka K, Kohda D, Fugo K, Kasahara M
  • Journal Title: J Immunol 180 Pages: 1678-85
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Quantification of lamivudine-resistant hepatitis B virus mutants by type-specific TaqMan minor groove binder probe assay in patients with chronic hepatitis B (2008)
  • Author(s): Yoshida S, Hige S, Yoshida M, Yamashita N, Fujisawa S, Sato K, Kitamura T, Nishimura M, Chuma M, Asaka M, Chiba H
  • Journal Title: Ann Clin Biochem 45 Pages: 59-64
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Soy consumption reduces the risk of non-small-cell lung cancers with Epidermal Growth Factor Receptor(EGFR) mutations among Japanese (2008)
  • Author(s): Matsuo K
  • Journal Title: Cancer Sci (In press)
  • Peer Reviewed
• [Journal Article] Quantification of lamivudine-resistant hepatitis B virus mutants by type-specific TaqMan minor groove binder probe assay in patients with chronic hepatitis B (2008)
  • Author(s): Yoshida S, et. al.
  • Journal Title: Ann Clin Biochem 45 Pages: 59-64
  • Peer Reviewed
• [Journal Article] Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2D (2008)
  • Author(s): Takada A, et. al.
  • Journal Title: J Immunol 180 Pages: 1678-1685
  • Peer Reviewed
• [Journal Article] Reduced apolipoprotein E-rich high-density liproprotein level at birth is restored to the normal range in patients with familial hypercholestero-lemia in the first year of life (2008)
  • Author(s): Nagasaka H, et. al.
  • Journal Title: J Clin Endocrinol Metab 93 Pages: 779-783
  • Peer Reviewed
• [Journal Article] Decreased risk of colorectal cancer with the high Natural-Killer(NK)-cell activity NKG2D genotype in Japanese (2008)
  • Author(s): Furue H, et. al.
  • Journal Title: Carcinogenesis 29(2) Pages: 316-320
  • Peer Reviewed
• [Journal Article] Opposite impact of NKG2D genotype by lifestyle exposure to risk of Aerodigestive tract cancer among Japanese (2008)
  • Author(s): Furue H, et. al.
  • Journal Title: Int J Cancer (In press)
  • Peer Reviewed
• [Journal Article] Gene-gene and gene-environment interactions between alcohol drinking habit and polymorphisms in alcohol-metabolizing enzyme genes and the risk of head and neck cancer in Japan (2007)
  • Author(s): Hiraki A
  • Journal Title: Cancer Sci 98 Pages: 1087-1091
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Multiple myeloma associated with sialyl salivary-type amylase (2007)
  • Author(s): Shigemura M
  • Journal Title: Clin Chim Acta 376 Pages: 121-125
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Increased fructose 2, 6-bisphosphate in peripheral blood mononuclear cells of patients with diabetes (2007)
  • Author(s): Atsumi T
  • Journal Title: Endocr J 54 Pages: 517-520
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Attenuated aerobic exercise capacity in CD36 deficiency (2007)
  • Author(s): Yanai H
  • Journal Title: J Med Genetics 44 Pages: 445-447
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Vitamin A-storing cells (stellate cells) (2007)
  • Author(s): Senoo H
  • Journal Title: Vitam Horm 75 Pages: 131-159
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Rat hepatic stellate cells acquire retinoid responsiveness after activation in vitro by post-transcriptional regulation of retinoic acid receptor alphagene expression (2007)
  • Author(s): Mezaki Y
  • Journal Title: Arch Biochem Biophys 465 Pages: 370-379
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'synoviolin' (2007)
  • Author(s): Yamasaki
  • Journal Title: EMBO J 26 Pages: 113-122
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Impact of the alcohol-dehydrogenase (ADH) 1C and ADH1B polymorphisms on drinking behavior in nonalcoholic Japanese. (2007)
  • Author(s): Matsuo K. Hiraki A. Hirose K, Wakai K, Ito H, Saito T, Tajima K
  • Journal Title: Hum Mutat 28 Pages: 506-510
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Gene-gene and gene-environment interactions between alcohol drinking habit and polymorphisms in alcohol-metabolizing enzyme genes and the risk of head and neck cancer in Japan. (2007)
  • Author(s): Hiraki A. Matsuo K. Wakai K, Suzuki T, Hasegawa Y, Tajima K
  • Journal Title: Cancer Sci 98 Pages: 1087-1091
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] High-risk HLA allele mismatch combinations responsible for severe acute graft versus host disease and implication for its molecular mechanism. (2007)
  • Author(s): Kawase T, Morishima Y, Matsuo K. Kashiwase K, Inoko H, Saji H, Kato S, Juji T, Kodera Y, Sasazuki T
  • Journal Title: Blood 110 Pages: 2235-2241
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Vitamin A-storing cells (stellate cells) (2007)
  • Author(s): Senoo. H. Kojima, N., Sato, M.
  • Journal Title: Vitam Horm 75 Pages: 131-159
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Rat hepatic stellate cells acquire retinoid responsiveness after activation in vitro by post-transcriptional regulation of retinoic acid receptor alpha gene expression. (2007)
  • Author(s): Mezaki, Y, Yoshikawa, K., Yamaguchi, N., Miura, M., Imai, K., Kato, S., Senoo. H.
  • Journal Title: Arch Biochem Biophys 465 Pages: 370-379
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] All-trans-retinol generated by rhodopsin photobleaching induces rapid recruitment of TIP47 to lipid droplets in the retinal pigment epithelium. Invest. (2007)
  • Author(s): Tsuiki, E., Fujita, A., Ohsaki, Y, Cheng, J., Irie, T, Yoshikawa, K., Senoo. H.. Mishima, K., Kitaoka, T., Fujimoto, Y
  • Journal Title: Ophthalm Vis Sci 48 Pages: 2858-2867
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'. (2007)
  • Author(s): Yamasaki, S., Yagishita, N., Sasaki, T., Nakazawa, M., Kato, Y, Yamadera, T, Bae, E., Toriyama, S., Ikeda, R, Zhang, L., Fujitani, K., Yoo, E., Tsuchimochi, K., Ohta, H., Aratani, S., Eguchi, K., Komiya, S., Maruyama, I., Higashi, N., Sato, M., Senoo. H.. Ochi, T., Yokoyama, S., Amano, T, Kim, J., Gay, S., Nishioka, k., Hukamizu, A., Tanaka, K., Nakajima, T.
  • Journal Title: EMBO J 26 Pages: 113-122
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Attenuated aerobic exercise capacity in CD36 deficiency. (2007)
  • Author(s): Yanai H., Watanabe I., Ishii K., Morimoto M., Fujiwara H., Yoshida S., Hui S. P., Matsuno K., Chiba H
  • Journal Title: Journal of Medical Genetics 44 Pages: 445-447
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Increased Fructose 2,6-bisphosphate in peripheral blood mononuclear cells of patients with diabetes (2007)
  • Author(s): Atsumi T, Chiba H. Yoshioka N, Bucala R, Koike T.
  • Journal Title: Endocr J 54 Pages: 517-520
  • NAID: 10019809194
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Multiple myeloma associated with sialyl salivary-type amylase. (2007)
  • Author(s): Shigemura M, Moriyama T, Shibuya H, Obara M, Endo T, Hashino S, Yokouchi H, Asaka M, Shimizu C, Chiba H. NishimuraM
  • Journal Title: Clin Chim Acta 376 Pages: 121-125
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Vitamin A-storing cell (stellate cell) system. In: Vitamin A: New Research. Ed. Loessing, I. T. (2007)
  • Author(s): Senoo. H.
  • Journal Title: Nova Science Publishers. New York Pages: 59-70
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Aberrant promoter methylation profile in pleural fluid DNA and clinico-pathological factors in patients with non-small cell lung cancer (2007)
  • Author(s): Katayama H, et. al.
  • Journal Title: Asian Pac J Cancer Prev 8 Pages: 221-224
  • Peer Reviewed
• [Journal Article] Gene-gene and gene-environment interactions between alcohol drinking habit and polymorphisms in alcohol-metabolizing enzyme genes and the risk of head and neck cancer in Japan (2007)
  • Author(s): Hiraki A, et. al.
  • Journal Title: Cancer Sci 98 Pages: 1087-1091
  • Peer Reviewed
• [Journal Article] One-carbon metabolism-related gene polymorphisms and risk of head and neck squamous cell carcinoma: Case-control study (2007)
  • Author(s): Suzuki T, et. al.
  • Journal Title: Cancer Sci 98 Pages: 1439-1446
  • Peer Reviewed
• [Journal Article] Impact of one-carbon metabolism-related gene polymorphisms on risk of lung cancer in Japan: a case-control study (2007)
  • Author(s): Suzuki T, et. al.
  • Journal Title: Carcinogenesis 28 Pages: 1718-1725
  • Peer Reviewed
• [Journal Article] Multiple myeloma associated with sialyl salivary-type amylase (2007)
  • Author(s): Shigemura M, et. al.
  • Journal Title: Clin Chim Acta 376 Pages: 121-125
  • Peer Reviewed
• [Journal Article] Increased fructose 2,6-bisphosphate in peripheral blood mononuclear cells of patients with diabetes (2007)
  • Author(s): Atsumi T, et. al.
  • Journal Title: Endocr J 54 Pages: 517-520
  • Peer Reviewed
• [Journal Article] Attenuated aerobic exercise capacity in CD36 deficiency (2007)
  • Author(s): Yanai H, et. al.
  • Journal Title: J Med Genetics 44 Pages: 445-447
  • Peer Reviewed
• [Journal Article] Vitamin A-storing cells(stellate cells) (2007)
  • Author(s): Senoo H, et. al.
  • Journal Title: Vitam Horm 75 Pages: 131-159
  • Peer Reviewed
• [Journal Article] Rat hepatic stellate cells acquire retinoid responsiveness after activation in vitro by post-transcriptional regulation of retinoic acid receptor alpha gene expression (2007)
  • Author(s): Mezaki Y, et. al.
  • Journal Title: Arch Biochem Biophys 465 Pages: 370-379
  • Peer Reviewed
• [Journal Article] Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'synoviolin' (2007)
  • Author(s): Yamasaki, et. al.
  • Journal Title: EMBO J 26 Pages: 113-122
  • Peer Reviewed
• [Journal Article] Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviol in' (2007)
  • Author(s): Yamasaki S.
  • Journal Title: EMBO J. 26(1) Pages: 113-122
• [Journal Article] A family predisposition to adult T-cell leukemia (2006)
  • Author(s): Nomura K
  • Journal Title: J Clin Exp Hematop 46(2) Pages: 67-71
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Two sibling cases of hydrops fetalis due to alloimmune anti-CD36 (Naka) antibody (2006)
  • Author(s): Okajima S
  • Journal Title: Thromb Haemost 95(2) Pages: 267-271
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] The possible contribution of a general glycosphingolipid transporter, GM2 activator protein, to atherosclerosis (2006)
  • Author(s): Yanai H
  • Journal Title: J Atheroscler Thromb 13(6) Pages: 281-285
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Distribution of retinylester-storing stellated cells in the arrowtooth halibut (2006)
  • Author(s): Yoshikawa K
  • Journal Title: Atheresthes evermanni, Comp. Biochem. Physiol. Part A 145 Pages: 280-286
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Oligo-astheno-teratozoospermia in mice lacking RA175/TSLC1/SynCAM/IGSF4A, a cell adhesion molecule in the immunoglobulin superfamily (2006)
  • Author(s): Fujita E
  • Journal Title: Molec Cell Biol 26 Pages: 718-726
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin' (2006)
  • Author(s): Yamasaki S
  • Journal Title: EMBO J 26(1) Pages: 113-122
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Impact of the alcohol-dehydrogenase (ADH) 1C and ADH1B polymorphisms on drinking behavior in nonalcoholic Japanese (2006)
  • Author(s): Matsuo K
  • Journal Title: Hum Mutat 28(5) Pages: 506-510
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] A gene-gene interaction between ALDH2 Glu487 Lys and ADH2 His47 Are polymorphisms regarding the risk of colorectal cancer in Japan (2006)
  • Author(s): Matsuo K
  • Journal Title: Carcinogenesis 27 Pages: 1018-1023
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Alcohol dehydrogenase 2 His47Arg polymorphisms influences drinking Habit independently of aldehyde dehydrogenase 2 Glu487 Lyspolymorphism : analysis of 2, 299 Japanese subject (2006)
  • Author(s): Matsuo K
  • Journal Title: Carcinogenesis 27 Pages: 1018-1023
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in Japan. (2006)
  • Author(s): Matsuo K. Ito H, Wakai K, Hirose K, Saito T, Suzuki T, Kato T, Hirai T, Kanemitsu Y, Hamajima H, Tajima K.
  • Journal Title: Carcinogenesis 27 Pages: 1018-1023
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Alcohol dehydrogenase 2 His47Arg polymorphism influences drinking habit independently of aldehyde dehydrogenase 2 Glu487Lys polymorphism: analylsis of 2,299 Japanese subjects. Cancer Epidemiol. (2006)
  • Author(s): Matsuo K. Wakai K, Hirose K, Ito H, Saito T, Tajima K
  • Journal Title: Biomarker Prev 15 Pages: 1009-1013
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Virus related cancers in Asian Pacific with special reference to adult T-cell leukemia/lymphoma Developments in cancer Epidemiology- prospects for cancer control in the Asian Pasific. In Developments in Cancer Epidemiology - (2006)
  • Author(s): Tajima K.
  • Journal Title: Prospects for Cancer Control in the Asian Pacific (Ed: Tominaga, S, et al)(Princess Takamatsu Cancer Research Fund) Pages: 79-84
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Meat, milk, saturated fatty acids, the Pro 12Ala and C161T polymorphisms of the PPARgamma gene and colorectal cancer risk in Japanese. (2006)
  • Author(s): Kuriki K, Hirose K, Matsuo K. Wakai K, Ito H, Kanemitsu Y, Hirai T, Kato T, Hamajima N, Takezaki T, Suzuki T, Saito T, Tanaka R, Tajima K.
  • Journal Title: Cancer Sci 97 Pages: 1226-1235
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] A family predisposition to adult T-cell leukemia. (2006)
  • Author(s): Nomura K, Utsunomiya A, Furusho H, Tara M, Hazeki M, Tokunaga M, Uozumi K, Yashiki S, Tajima K. Sonoda S.
  • Journal Title: J Clin Exp Hematoopatho 46 Pages: 67-71
  • NAID: 10018396785
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Polymorphism in the 3'-untranslated region of the thymidylate synthase gene and sensitivity of stomach cancer to fluoropyrimidine-based chemotherapy (2006)
  • Author(s): Lu J.W.
  • Journal Title: J.Hum.Genet. 51(3) Pages: 155-160
• [Journal Article] A polymorphism of C-to-T substitution at -31 IL1B is associated with the risk of advanced gastric adenocarcinoma in a Japanese population (2006)
  • Author(s): Ikehara S.K.
  • Journal Title: J.Hum.Genet. 51(11) Pages: 927-933
• [Journal Article] A family predisposition to adult T-cell leukemia (2006)
  • Author(s): Nomura K.
  • Journal Title: J.Clin.Exp.Hematop. 46(2) Pages: 67-71
• [Journal Article] Two sibling cases of hydrops fetalis due to alloimmune anti-CD36 (Nak a) antibody (2006)
  • Author(s): Okajima S.
  • Journal Title: Thromb Haemost. 95(2) Pages: 267-271
• [Journal Article] The possible contribution of a general glycosphingolipid transporter, GM2 activator protein, to atherosclerosis (2006)
  • Author(s): Yanai H.
  • Journal Title: J.Atheroscler Thromb. 13(6) Pages: 281-285
• [Journal Article] Distribution of retinylester-storing stellated cells in the arrowtooth halibut (2006)
  • Author(s): Yoshikawa K.
  • Journal Title: Atheresthes evermanni, Comp.Biochem.Physiol. Part A 145 Pages: 280-286
• [Journal Article] Oligo-astheno-teratozoospermia in mice lacking RA175/TSLC1/SynCAN/IGSF4A, a cell adhesion molecule in the immunoglobulin superfamily (2006)
  • Author(s): Fujita E.
  • Journal Title: Molec.Cell.Biol. 26 Pages: 718-726
• [Journal Article] Impact of the alcohol-dehydrogenase (ADH) 1C and ADH1B polymorphisms on drinking behavior in nonalcoholic Japanese
  • Author(s): Matsuo K.
  • Journal Title: Hum.Mutat. (In press)
• [Journal Article] Vitamin A-storing cells (stellate cells)
  • Author(s): Senoo H.
  • Journal Title: Vitamins and Hormones (In press)
• [Presentation] Anthropo-genetic approach on mongoloids HTLV dispersal in Pan-Pacific Regions (2007)
  • Author(s): Tajima K
  • Organizer: 第13回国際ヒトレトロウイルスHTLV会議
  • Place of Presentation: 箱 根
  • Year and Date: 2007-05-24
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Anthropo-genetic approach on mongoloids HTLV dispersal in Pan-Pacific Regions (2007)
  • Author(s): Tajima K, et. al.
  • Organizer: 第13回国際ヒトレトロウィルスHTLV会議
  • Place of Presentation: 箱根
  • Year and Date: 2007-05-24
• [Presentation] Anthropo-genetic approach on mongoloids HTLV dispersal in Pan-pacific regions. 13^<th> International Conference on Human Retrovirology (2007)
  • Author(s): Tajima K, et al
  • Organizer: HTLV and Related Viruses
  • Place of Presentation: Hakone
  • Description: 「研究成果報告書概要(欧文)」より
• [Book] Vitamin A-Strong Cell (Stellate Cell) System (Ed. Loessing IT) (2007)
  • Author(s): Senoo H
  • Total Pages: 12
  • Publisher: Nova Science Publishers Inc.
  • Description: 「研究成果報告書概要(和文)」より
• [Book] Developments in Cancer Epidemiology-Prospects for Cancer Control in the Asian Pacific (Ed. Tominaga S) (2006)
  • Author(s): Tajima K
  • Total Pages: 6
  • Publisher: Princess Takamatsu Cancer Research
  • Description: 「研究成果報告書概要(和文)」より