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Mapping of the white matter tracts using diffusion tensor MRI : location of the pyramidal tract using normalization

Research Project

Project/Area Number 18500261
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Nerve anatomy/Neuropathology
Research InstitutionThe University of Tokyo

Principal Investigator

AOKI Shigeki  The University of Tokyo, 医学部・附属病院, 准教授 (80222470)

Co-Investigator(Kenkyū-buntansha) 阿部 修  東京大学, 医学部・附属病院, 准教授 (50302716)
増谷 佳孝  東京大学, 医学部・附属病院, 講師 (20345193)
笠井 清登  東京大学, 医学部・附属病院, 教授 (80322056)
Co-Investigator(Renkei-kenkyūsha) ABE Osamu  東京大学, 医学部・附属病院, 准教授 (50302716)
MASUTANI Yoshitaka  東京大学, 医学部・附属病院, 講師 (20345193)
KASAI Kiyoto  東京大学, 医学部・附属病院, 教授 (80322056)
Project Period (FY) 2006 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,310,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥510,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2006: ¥1,100,000 (Direct Cost: ¥1,100,000)
Keywords拡散テンソル・錐体路 / 白質路 / 拡散テンソル / MRI / 脳白質 / 錐体路 / 脳梗塞 / 標準脳 / 拡散テンソルtrastography / 高磁場MRI / 拡散テンソルtractography
Research Abstract

拡散テンソルtractography を用いて個人の錐体路の可視化を行い、それを標準脳に合わせてmappingし、錐体路近傍の梗塞について症状との対比を行った。Mappingされた錐体路と梗塞巣との位置関係は、梗塞による症状と有意な相関を示した。

Report

(4 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (21 results)

All 2009 2008 2007 2006 Other

All Journal Article (16 results) (of which Peer Reviewed: 7 results) Presentation (2 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Structural and diffusional brain abnormality related to relatively low level alcohol consumption2009

    • Author(s)
      Sasaki H, Abe O, et al.
    • Journal Title

      Neuroimage (Epub)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tolerance of pyramidal tract to gamma knife radiosurgery based on diffusion-tensor tractography2008

    • Author(s)
      Maruyama K, Kamada K, Ota T, Koga T, Itoh D, Ino K Aoki S, Tago M, Masutani Y, Shin M, Saito N.
    • Journal Title

      Int J Radiat Oncol Biol Phys. 70

      Pages: 1330-5

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Diffusion tensor tractography predicts motor functional outcome in patients with spontaneous intracerebral hemorrhage2008

    • Author(s)
      Yoshioka H, Horikoshi T, Aoki S, Hori M, Ishigame K Uchida M, Sugita M,Araki T, Kinouchi H.
    • Journal Title

      Neurosurgery 62

      Pages: 97-103

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tract-specific analysis of the superior occipitofrontal fasciculus in schizophrenia.2008

    • Author(s)
      Kunimatsu N, Aoki S, et al.
    • Journal Title

      Psychiatry Res 164

      Pages: 198-205

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Silent white matter lesion in linear scleroderma en coup de sabre2008

    • Author(s)
      Sakai M, Aoki S, et al.
    • Journal Title

      J Comput Assist Tomogr 32

      Pages: 822-824

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 中枢神経系MRIにおける拡散テンソル解析の基礎と臨床応用: 解析ソフトウエア開発から臨床応用までのトランスレーショナルリサーチ2008

    • Author(s)
      青木茂樹
    • Journal Title

      最新医学 63(2)

      Pages: 306-349

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Utilization of diffusion tensor tractography in combination with spatial normalization to assess involvement of the corticospinal tract in capsular/pericapsular stroke : Feasibility and clinical implications2007

    • Author(s)
      Kunimatsu A, Itoh D, Nakata Y, Kunimatsu N, Aoki S, Masutani Y, Abe O,Yoshida M, Minami M, Ohtomo K.
    • Journal Title

      J Magn Reson Imaging

      Pages: 1399-404

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Functional identification of the primary motor area by corticospinal tractography2007

    • Author(s)
      Kamada K, Sawamura Y, Takeuchi F, Kawaguchi H, Kuriki S, Todo T, Morita A, Masutani Y, Aoki S, Kirino T.
    • Journal Title

      Neurosurgery 61

      Pages: 166-76

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tolerance of pyramidal tract to gamma knife radiosurgery based on diffusion-tensor tractography.2007

    • Author(s)
      Maruyama K
    • Journal Title

      Int J Radiat Oncol Biol Phys Epub(Nov 1)

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Utilization of diffusion tensor tractography in combination with spatial normalization to assess involvement of the corticospinal tract in capsular/pericapsular stroke:2007

    • Author(s)
      Kunimatsu A
    • Journal Title

      J Magn Reson Imaging 26(6)

      Pages: 1399-1404

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Visualization of the frontotemporal language fibers by tractography combined with functional magnetic resonance imaging and magnetoencephalography.2007

    • Author(s)
      Kamada K
    • Journal Title

      J Neurosurg 106(1)

      Pages: 90-98

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Flexible ex vivo phantoms for validation of diffusion tensor tractography on aclinical scanner.2006

    • Author(s)
      Watanabe M
    • Journal Title

      Radiat Med 24(9)

      Pages: 605-609

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Aging in the CNS : Comparison of gray/white matter volume and diffusion tensor data.2006

    • Author(s)
      Abe O
    • Journal Title

      Neurobiol Aging E pub

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Corticospinal tracts by diffusion tensor tractography in patients with arteriovenous malformations.2006

    • Author(s)
      Itoh D
    • Journal Title

      J Comput Assist Tomogr 30(4)

      Pages: 618-623

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Voxel-based diffusion tensor analysis reveals aberrant anterior cingulum integrity in posttraumatic stress disorder due to terrorism.2006

    • Author(s)
      Abe O
    • Journal Title

      Psychiatry Res 146(3)

      Pages: 231-242

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 拡散テンソルMRIによる脳白質路の描出と定量的評価2006

    • Author(s)
      青木茂樹
    • Journal Title

      神経研究の進歩 50(6)

      Pages: 964-970

    • Related Report
      2006 Annual Research Report
  • [Presentation] 拡散テンソルtractography : どこまでできるか2008

    • Author(s)
      青木茂樹
    • Organizer
      脳循環代謝学会
    • Place of Presentation
      東京ドームホテル
    • Year and Date
      2008-11-07
    • Related Report
      2008 Final Research Report
  • [Presentation] 拡散テンソルtractography:どこまでできるか2008

    • Author(s)
      青木茂樹
    • Organizer
      脳循環代謝学会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-07
    • Related Report
      2008 Annual Research Report
  • [Book] 所見からせまる脳MRI2008

    • Author(s)
      青木茂樹、下野太郎, 他
    • Total Pages
      512
    • Publisher
      秀潤社
    • Related Report
      2008 Final Research Report
  • [Book] 所見からせまる脳MRI2008

    • Author(s)
      青木茂樹
    • Total Pages
      511
    • Publisher
      秀潤社
    • Related Report
      2008 Annual Research Report
  • [Remarks] 日本磁気共鳴学会研究班、研究グループ主幹

    • Related Report
      2008 Final Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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