Fundamental Study on Molecular Imaging by Fluorescent X-Ray CT

• Project/Area Number: 18500341
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Biomedical engineering/Biological material science
• Research Institution: Yamagata University
• Principal Investigator: YUASA Tetsuya Yamagata University, Graduate School of Science and Engineering, 教授 (30240146)
• Co-Investigator(Kenkyū-buntansha): TAKEDA Tohoru University of Tsukuba, Graduate School of Comprehensive Human Sciences, 講師 (10197311) ; WU Jin University of Tsukuba, Graduate School of Comprehensive Human Sciences, 講師 (20375512)
• Project Period (FY): 2006 – 2007
• Project Status: Completed (Fiscal Year 2007)
• Budget Amount: ¥4,050,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥450,000); Fiscal Year 2007: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2006: ¥2,100,000 (Direct Cost: ¥2,100,000)
• Keywords: Synchrotron X-Ray / Fluorescent X-Ray / Computed Tomography / Tomoeranhic Imaging / Molecular Imaging

Research Abstract

Fluorescent x-ray computed tomography (FXCT) that can detect and image a trace of non-radioactive imaging agent, e. g., iodine, in a biomedical subject at a high spatial resolution can be a novel molecular imaging modality. Presently, we are developing an FXCT system using synchrotron radiation as an x-ray source for in-vivo imaging brains of small animals such as mouse, rat, and so on. For the purpose, we must overcome the following two difficulties damaging an image-quality: One difficulty is that the number of projections is remarkably restricted due to the long data-acquisition time. In order to reduce the measurement time, we propose to eliminate unnecessary beam scans by adaptively and efficiently controlling the scanning according to the subject size. The other difficulty is that the measured data are contaminated by inevitable physical factors. Here, we propose data-processing methods to estimate reliable projections from raw data. The efficacies of the proposed methods are demonstrated using physical-phantom images and an in-vivo image of mouse brain, which were reconstructed from experimental data acquired in KEK, Japan.

Research Products

• [Journal Article] 3-D Reconstruction of High-Guctal Carcinoma In Situ of the Breast with Casting Type Calcifications using Refraction-based X-Ray CT (2008)
  • Author(s): S., Ichihara・M., Ando・E., Hashimoto・A., Maksimenko・H., Sugiyama・C., Ohbayashi・T., Yuasa・K., Yamasaki・Y., Arai・K., Mori・T., Endo
  • Journal Title: Virchows Archiv 452 Pages: 41-47
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] 3-D Reconstruction of High-Grade Ductal Carcinoma In Situ of the Breast with Casting Type Calcifications using Refraction-based X-Ray CT (2008)
  • Author(s): S. Ichihara, M. Ando, E. Hashimoto, A. Maksimenko, H. Sugiyama, C. Ohbayashi, T. Yuasa, K. Yamasaki, Y. Arai, K. Mori, and T. Endo
  • Journal Title: Virchows Archiv Vol.452, No.1 Pages: 41-47
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] 3-D Reconstruction of High-Grade Ductal Carcinoma In Situ of the Breast with Casting Type Calcifications using Refraction-based X-Ray CT (2008)
  • Author(s): S. Ichihara, M. Ando, E. Hashimoto, A. Maksimenko, H. Sugiyama, C. Ohbayashi, T. Yuasa, K. Yamasaki, Y. Arai, K. Mori, and T.Endo
  • Journal Title: Virchows Archiv 452 Pages: 41-47
  • Peer Reviewed
• [Journal Article] Refraction-based tomosynthesis: Proof of the concept (2007)
  • Author(s): A., Maksimenko・T., Yuasa・M., Ando・E., Hashimoto
  • Journal Title: Appl. Phys. Lett 91 Pages: 234108-234108
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] 蛍光X線CT画像におけるヨウ素濃度の定量的推定 (2007)
  • Author(s): 那須川清太・霍 慶凱・舞草伯秀・呉 勁・Thet-Thet-Lwin・武田 徹・湯浅哲也・兵藤一行・赤塚孝雄
  • Journal Title: Medlical Imaging Technology 25 Pages: 251-256
  • NAID: 10019938712
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Whole-atom Compton scattering cross-sections and individual shell cross-sections for the biological elements in the energy region from 1 to 4 keV (2007)
  • Author(s): D., V., Rao・T., Yuasa・T., Akasuka・G., Tromba・T., Takeda・R., Cesareo・A., Brunetti・G., E., Gigigante
  • Journal Title: Nuclear Instruments and Methods in Physics Research B 261 Pages: 193-196
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Fundamental study on subharmonic imaging by irradiation of amplitude-modulated ultrasound waves (2007)
  • Author(s): N., Maikusa・T., Fukami・T., Yuasa・Y., Tamura・T., Akatsuka
  • Journal Title: J. Acoust. Soc. Am. 122 Pages: 672-676
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Quantitative evaluation of myocardial function by a volume-normalized map generated from relative blood flow (2007)
  • Author(s): T., Fukami・H., Sato・J., wu・Thet-Thet-Lwin・T., Yuasa・S., Kawano・K., Iida・T., Akatsuka・H., Hontani・T., Takeda・M., tamura・H., Yokota
  • Journal Title: Physics in Medicine and Biology 52 Pages: 4311-4330
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Near-infrared laser tomographic imaging with right-angled scattered coherent light using an optical heterodyne-detection-based confocal scanning system (2007)
  • Author(s): I., Nishidate・M., Goto・Y., Sasaki・T., Yuasa・B., Devaraj・Q., Niizeki・T., Akatsuka
  • Journal Title: Applied Optics 46 Pages: 2123-2130
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Myocardinal Fatty Acid Metabolic Imaging by Fluorescent X-Ray Computed Tomography Imaging (2007)
  • Author(s): Thet-Thet-Lwin・T., Takeda・J., Wu・N., Sunaguchi・T., Murakami・S., Mouri・S., Nasukawa・Q., Huo・T., Yuasa・K., Hyodo・T., Akatsuka
  • Journal Title: Journal of Synchrotron Radiation 14/1 Pages: 158-162
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Refraction-based tomosynthesis : Proof of the concept (2007)
  • Author(s): Maksimenko, T. Yuasa, M. Ando, and E. Hashimoto
  • Journal Title: Appl. Phys. Lett. 91 Pages: 234108-234108
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Whole-atom Compton scattering cross-sections and individual shell cross-sections for the biological elements in the energy region from 1 to 4 keV (2007)
  • Author(s): D. V. Rao, T. Yuasa T. Akatsuka, G. Tromba, T. Takeda, R. Cesareo, A. Brunetti, G. E. Gigante
  • Journal Title: Nuclear Instruments and Methods in Physics Research B Vol.261, No.1-2 Pages: 193-196
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Fundamental study on subharmonic imaging by irradiation of amplitude-modulated ultrasound waves (2007)
  • Author(s): N. Maikusa, T. Fukami, T. Yuasa. Y. Tamura, and T. Akatsuka
  • Journal Title: J. Acoust. Soc. Am. Vol.122, No.1 Pages: 672-676
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Quantitative evaluation of myocardial function by a volume-normalized map generated from relative blood flow (2007)
  • Author(s): T. Fukami, H. Sato, J. Wu, Thet-Thet-Lwin, T. Yuasa, S. Kawano, K. lida, T. Akatsuka, H. Hontani, T. Takeda, M. Tamura, and H. Yokota
  • Journal Title: Physics in Medicine and Biology Vol.52, No.14 Pages: 4311-4330
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Near-Infrared laser tomographic imaging with right-angled scattered coherent light using an optical heterodyne-detection-based confocal scanning system (2007)
  • Author(s): Nishidate, M. Goto, Y. Sasaki, T. Yuasa B. Devaraj, Q. Niizeki, T. Akatsuka
  • Journal Title: Applied Optics Vol.46, No.11 Pages: 2123-2130
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Myocardinal Fatty Acid Metabolic Imaging by Fluorescent X-Ray Computed Tomography Imaging (2007)
  • Author(s): Thet-Thet-Lwin, T. Takeda, J. Wu, N. Sunaguchi, T. Murakami, S. Mouri, S. Nasukawa, Q. Huo, T. Yuasa, K. Hyodo, T. Akatsuka
  • Journal Title: Journal of Synchrotron Radiation Vol.14, No.1 Pages: 158-162
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Refraction-based tomosynthesis: Proof of the concept (2007)
  • Author(s): A. Maksimenko, T. Yuasa, M. Ando, and E. Hashimoto
  • Journal Title: Appl. Phys. Lett. 91 Pages: 234108-234108
  • Peer Reviewed
• [Journal Article] 蛍光X線CT画像におけるヨウ素濃度の定量的推定 (2007)
  • Author(s): 那須川清太, 崔慶凱, 舞草伯秀, 呉勤, Thet-Thet-Lwin, 武田徹, 湯浅哲也, 兵藤一行, 赤塚孝雄
  • Journal Title: Medical Imaging Technology 25 Pages: 251-256
  • NAID: 10019938712
  • Peer Reviewed
• [Journal Article] Whole-atom Compton scattering cross-sections and individual shell cross-sections for the biological elements in the energy region from 1 to 4 keV (2007)
  • Author(s): D. V. Rao, T. Yuasa, T. Akatsuka, G. Tromba, T. Takeda, R. Cesareo, A. Brunetti, G.E. Gigante
  • Journal Title: Nuclear Instruments and Methods in Physics Research B 261 Pages: 193-196
  • Peer Reviewed
• [Journal Article] Fundamental study on subharmonic imaging by irradiation of amplitude-modulated ultrasound waves (2007)
  • Author(s): N. Maikusa, T. Fukami, T. Yuasa, Y. Tamura, and T. Akatsuka
  • Journal Title: J. Acoust. Soc. Am. 122 Pages: 672-676
  • Peer Reviewed
• [Journal Article] Quantitative evaluation of myocardial function by a volume-normalized map generated from relative blood flow (2007)
  • Author(s): T. Fukami, H. Sato, J. Wu, Thet-Thet-Lwin, T. Yuasa, S. Kawano, K. Iida, T. Akatsuka, H. Hontani, T. Takeda, M. Tamura, and H. Yokota
  • Journal Title: Physics in Medicine and Biology 52 Pages: 4311-4330
  • Peer Reviewed
• [Journal Article] Near-infrazed laser tomographic imaging with right-angled scattered coherent light using an optical heterodyne-detection-based confocal scanning system (2007)
  • Author(s): I. Nishidate, M. Goto, Y. Sasaki, T. Yuasa, B. Devaraj, Q. Niizeki, T. Akatsuka
  • Journal Title: Applied Optics 46 Pages: 2123-2130
  • Peer Reviewed
• [Journal Article] Myocardinal Fatty Acid Metabolic Imaging by Fluorescent X-Ray Computed Tomography Imaging (2007)
  • Author(s): Thet-Thet-Lwin, T.Takeda, J.Wu, N.Sunaguchi, T.Murakami, S.Mouri, S.Nasukawa, Q.Huo, T.Yuasa, K.Hyodo, T.Akatsuka
  • Journal Title: Journal of Synchrotron Radiation 14/1 Pages: 158-162
• [Journal Article] 2D and 3D Visualization of Ductal Carcinoma in situ (DCIS) using X-Ray Refraction Contrast (2006)
  • Author(s): M., Ando・A., Maksimenko・T., Yuasa・E., Hashimoto・K., Yamasaki・C., ohbayashi・H., Sugiyama・K., Hyodo・T., Kimura・H., Esumi・T., Akatsuka・G., Li・D., Xian・E., Ueno・H., Bando・S., Ichihar
  • Journal Title: Bioimages 1 Pages: 1-8
  • NAID: 10020936889
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] First attempt at 3D X-ray visualization of DCIS (ductal carcinoma in situ) due to refiraction contrast - In good relation to pathological view (2006)
  • Author(s): M., Ando・T., Akatsuka・H., Bando・Y., Chikaura・T., Endo・E., Hashimoto・K., Hirano・K., Hyodo・S., Ichihara・A., Maksimenko・C., Ohbayashi・H., Sugiyama・E., Ueno・K., Yamasaki・T., Yuasa
  • Journal Title: Digital Mammography, proceedings Lecture Notes in Computer Science 4046 Pages: 525-532
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Hard x-ray region tomographic reconstruction of the reftactive index gradient vector field : Imaging principles and comparisons to diffraction enhanced imaging based computed tomography (2006)
  • Author(s): T., Yuasa・A., Maksimenko・E., Hashimoto・H., Sugiyama・K., Hyodo・T., Akatsuka・M., Ando
  • Journal Title: Optics Letters 31/12 Pages: 1818-1820
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Interlaced X-ray Microplanar Arrays: A Novel Radiosurgery Approach with Clinical Potential (2006)
  • Author(s): A., Dilmanian・Z., Zhong・T., Bacarian・H., Benveniste・P., romanelli・R., Wang・J., Welwart・T., Yuasa・E., M., Rosen・D., J., Anschel
  • Journal Title: Proc. Natl. Acad. Sci. USA 103/25 Pages: 9709-9714
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Images of biological soft tissue using synchrotron and laser CT system (2006)
  • Author(s): D., V., Rao・T., Yuasa・T., Akatsuka・G., Tromba・M., Z., Hasan・T., Tkakeda・B., Devaraj
  • Journal Title: Radiation Measurements 41/2 Pages: 177-182
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Tomographic images of few soft materials and embedded biological soft tissue using tube source of X-rays at optimum energy (2006)
  • Author(s): D., V., Rao・T., Yuasa・T., Akatsuka・R., Cesareo・G., E., Gigante・M., Z., Hasan・T., Takeda
  • Journal Title: NDT & E international 39/1 Pages: 34-38
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Tomographic images of few soft materials and embedded biological soft tissue using tube source of X-rays at optimum energy (2006)
  • Author(s): D., V., Rao・<T., Yuasa>・T., Akatsuka・R., Cesareo・G., E., Gigante・M., Z., Hasan・T., Takeda
  • Journal Title: NDT & E international 39/1 Pages: 34-38
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] 画素値の確率分布に基づくPET/CT画像中の腫瘍領域の抽出 (2006)
  • Author(s): 新田修平・本谷秀堅・深見忠典・湯浅哲也・赤塚孝雄・呉 勤・武田 徹・織内 昇・遠藤啓吾・渡邉順久
  • Journal Title: Medical Imaging Technology 24/5 Pages: 409-418
  • NAID: 10019266175
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] PET/CT画像からの腫瘍候補領域自動抽出による支援診断システム (2006)
  • Author(s): 新田修平・本田清士・糟谷友美・本谷秀堅・深見忠典・湯浅哲也・赤塚孝雄・呉 勁・武田 徹
  • Journal Title: Medical Imaging Technology 24/3 Pages: 181-190
  • NAID: 10019160391
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Progress in biomedical application of phase-contrast x-ray imaging and fluorescent x-ray CT (2006)
  • Author(s): T., Takeda・J., Wu・T., T., Lwin・A., Yoneyama・Y., Hirai・K., Hyodo・N., Sunaguchi・T., Yuasa・M., Minami・K., Kose・T., Akatsuka:
  • Journal Title: Proc. SPIE 6318/38
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Fusion imaging of fluorescent and phase-contrast x-ray computed tomography using synchron radiation in medical biology (2006)
  • Author(s): J., Wu・T., Takeda・T., T., Lwin・N., Sunaguchi・T., Yuasa・M., Minami・T., Akatsuka
  • Journal Title: Proc.SPIE 6318/38 Pages: 631828-631828
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Spatial Resolution Effect in Myocardinal Fatty Acid Metabolic Image in Fluorescent X-ray CT (2006)
  • Author(s): T., takeda・J., Wu・Thet-Thet-Lwin・N., Sunaguchi・T., Yuasa・F., A., Dilmanian・M., Minami・T., Akatsuka
  • Journal Title: Proc. 12th World Congress on Heart Disease Pages: 197-200
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] First attempt of the medical application of the refraction-based computed tomography (2006)
  • Author(s): A., Maksimenko・E., Hashimoto・M., Ando・H., Sugiyama・T., Yuasa
  • Journal Title: Proc. SPIE 6142 Pages: 614239-614239
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Application of x-ray computed tomography based on the refraction contrast to biomedicine (2006)
  • Author(s): E., Hashimoto・A., Maksimenko・H., Sugiyama・K., Hyodo・D., Shimao・T., Yuasa・Y., Nishino・T., Ishikawa・K., Mori・Y., Arai・K., Hirano・M., Ando
  • Journal Title: Proc. SPIE 6142 Pages: 614213-614213
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] First attempt of the medical application of the refraction-based computed tomography (2006)
  • Author(s): A., Maksimenko・E., Hashimoto・M., Ando・H., Sugiyama・<T., Yuasa>
  • Journal Title: Proc. SPIE 6142 Pages: 614239-614239
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] 2D and 3D Visualization of Ductal Carcinoma in situ(DCIS) using X-Ray Refraction Contrast (2006)
  • Author(s): M. Ando, A. Maksimenko, T. Yuasa, E. Hashimoto, K. Yamasaki, C. Ohbayashi, H. Sugiyama, K. Hyodo, T. Kimura, H. Esumi, T. Akatsuka, G. Li, D. Xian, E. Ueno, H. Bando, S. Ichihara, T. Endo, N. M. and H. Nishio
  • Journal Title: Bioimages Vol.14 Pages: 1-8
  • NAID: 10020936889
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] First attempt at 3D X-ray visualization of DCIS(ductal carcinoma in situ) due to refraction contrast-In good relation to pathological view, Digital Mammography (2006)
  • Author(s): M. Ando, T. Akatsuka, H. Bando, Y. Chikaura, T. Endo, E. Hashimoto, K. Hirano, K. Hyodo, S. Ichihara, A. Maksimenko, C. Ohbayashi, H. Sugiyama, E. Ueno, K. Yamasaki, T. Yuasa
  • Journal Title: Proceedings Lecture Notes in Computer Science 4046 Pages: 525-532
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Hard x-ray region tomographic reconstruction of the refractive index gradient vector field : Imaging principles and comparisons to diffraction enhanced imaging based computed tomography (2006)
  • Author(s): T. Yuasa. A. Maksimenko, E. Hashimoto, H. Sugiyama, K. Hyodo, T. Akatsuka, and M. Ando
  • Journal Title: Optics Letters Vol.31, No.12 Pages: 1818-1820
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Interlaced X-Ray Microplanar Arrays : A Novel Radiosurgery Approach with Clinical Potential (2006)
  • Author(s): F. A. Dilmanian, Z. Zhong, T. Bacarian, H. Benveniste, P. Romanelli, R. Wang, J. Welwart, T. Yuasa. E. M. Rosen, and D. J. Anschel
  • Journal Title: Proc. Natl. Acad. Sci. USA Vol.103, No.25 Pages: 9709-9714
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Images of biological soft tissue using synchrotron and laser CT system (2006)
  • Author(s): D. V. Rao, T. Yuasa. T. Akatsuka, G. Tromba, M. Z. Hasan, T. Takeda, and B. Devaraj
  • Journal Title: Radiation Measurements Vol.41, Issue 2 Pages: 177-182
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Tomographic images of few soft materials and embedded biological soft tissue using tube source of X-rays at optimum energy (2006)
  • Author(s): D. V. Rao, T. Yuasa, T. Akatsuka, R. Cesareo, G. E. Gigante, M. Z. Hasan, and T. Takeda
  • Journal Title: NDT&E international Vol.39, No.1 Pages: 34-38
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] 2D and 3D Visualization of Ductal Carcinoma in situ (DCIS) using X-Ray Refraction Contrast (2006)
  • Author(s): M.Ando, A.Maksimenko, T.Yuasa, E.Hashimoto, K.Yamasaki, C.Ohbayashi, H.Sugiyama, K.Hyodo, T.Kimura, H.Esumi, T.Akatsuka, G.Li, D.Xian, E.Ueno, H.Bando, S.Ichihara, T.Endo, N.M., H.Nishio
  • Journal Title: Bioimages 1 Pages: 1-8
  • NAID: 10020936889
• [Journal Article] First attempt at 3D X-ray visualization of DCIS (ductal carcinoma in situ) due to refraction contrast-In good relation to pathological view (2006)
  • Author(s): M.Ando, T.Akatsuka, H.Bando, Y.Chikaura, T.Endo, E.Hashimoto, K.Hirano, K.Hyodo, S.Ichihara, A.Maksimenko, C.Ohbayashi, H.Sugiyamam, E.Ueno, K.Yamasaki, T.Yuasa:
  • Journal Title: Digital Mammography,Proceedings Lecture Notes in Computer Science 4046 Pages: 525-532
• [Journal Article] Hard x-ray region tomographic reconstrction of the refractive index gradient vector field : Imaging principles and comparisions to diffraction enhanced imaging based computed tomography (2006)
  • Author(s): T.Yuasa, A.Maksimenko, E.Hashimoto, H.Sugiyama, K.Hyodo, T.Akatsuka, M.Ando
  • Journal Title: Optics Letters 31/12 Pages: 1818-1820
• [Journal Article] Interlaced X-ray Microplanar Arrays : A Novel Radiosurgery Approach with Clinical Potential (2006)
  • Author(s): A.Dilmanian, Z.Zhong, Bacarian, H.Benveniste, P.Romanelli, R.Wang, J.Welwart, T.Yuasa, E.M.Rosen, D.J.Anschel:
  • Journal Title: Proc.Natl.Acad.Sci.USA 103/25 Pages: 9709-9714
• [Journal Article] Images of biological soft tissue using synchrotron and laser CT system (2006)
  • Author(s): D.V.Rao, T.Yuasa, T.Akatsuka, G.Tromba, M.Z.Hasan, T.Takeda, B.Devaraj
  • Journal Title: Radiation Measurements 41/2 Pages: 177-182
• [Journal Article] Tomographic images of few soft materials and embedded biological soft issue using tube source of X-rays at optimum energy (2006)
  • Author(s): D.V.Rao, T.Yuasa, T.Akatsuka, R.Cesareo, G.E.Gigante, M.Z.Hasan, T.Takeda
  • Journal Title: NDT ＆ E international 39/1 Pages: 34-38
• [Journal Article] 画素値の確率分布に基づくPET/CT画像中の腫瘍領域の抽出 (2006)
  • Author(s): 新田修平, 本谷秀堅, 深見忠典, 湯浅哲也, 赤塚孝雄, 呉勁, 武田徹, 織内昇, 遠藤啓吾, 渡邉順久
  • Journal Title: Medical Imaging Technology 24/5 Pages: 409-418
  • NAID: 10019266175
• [Journal Article] PET/CT画像からの腫瘍候補領域自動抽出による支援診断システム (2006)
  • Author(s): 新田修平, 本田清士, 糟谷友美, 本谷秀堅, 深見忠典, 湯浅哲也, 赤塚孝雄, 呉勁, 武田徹
  • Journal Title: Medical Imaging Technology 24/3 Pages: 181-190
  • NAID: 10019160391
• [Journal Article] Progress in biomedical application of phase-contrast x-ray imaging and fluorescent x-ray CT (2006)
  • Author(s): T.Takeda, j.Wu, T.T.Lwin, A.Yoneyama, Y.Hirai, K.Hyodo, N.Sunaguchi, T.Yuasa, M.Minami, K.Kose, T.Akatsuka:
  • Journal Title: Proc.SPIE 6318/38
• [Journal Article] Fusion imaging of fluorescent and phase-contrast x-ray computed tomography using (2006)
  • Author(s): J.Wu, T.Takeda, T.T.Lwin, N.Sunaguchi, T.Yuasa, M.Minami, T.Akatsuka
  • Journal Title: Proc.SPIE 6318/38 Pages: 631828-631828
• [Journal Article] Spatial Resolution Effect in Myocardinal Fatty Acid Metabolic Image in Fluorescent X-ray CT (2006)
  • Author(s): T.takeda, J.Wu, Thet-Thet-Lwin, N.Sunaguchi, T.Yuasa, F.A.Dilmanian, M.Minami, T.Akatsuka
  • Journal Title: Proc. 12th World Congress on Heart Disease Pages: 197-200
• [Journal Article] First attempt of the medical application of the refraction-based computed tomography (2006)
  • Author(s): A.Maksimenko, E.Hashimoto, M.Ando, H.Sugiyama, T.Yuasa
  • Journal Title: Proc.SPIE 6142 Pages: 614239-614239
• [Journal Article] Application of x-ray computed tomography based on the refraction contrast to biomedicine (2006)
  • Author(s): E.Hashimoto, A.Maksimenko, H.Sugiyama, K.Hyodo, D.Shimao, T.Yuasa, Y.Nishino, T.Ishikawa, K.Mori, Y.Arai, K.Hirano, M.Ando
  • Journal Title: Proc.SPIE 6142 Pages: 614213-614213
• [Presentation] in-vivo蛍光X線CT撮像時における脳内代謝による造影剤濃度の時間的減衰に関する補正方法 (2008)
  • Author(s): 那須川清太・霍 慶凱・舞草伯秀・深見忠典・呉 勁・Thet Thet Lwin・武田 徹・湯浅哲也・兵藤一行・赤塚孝雄
  • Organizer: 電子情報通信学会研究会
  • Place of Presentation: 沖縄
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 蛍光X線CTにおける再構成画像の空間分解能評価 (2008)
  • Author(s): 霍 慶凱・那須川清太・舞草伯秀・呉 勁・Thet Thet Lwin・武田 徹・湯浅哲也・兵藤一行・赤塚孝雄
  • Organizer: 電子情報通信学会研究会
  • Place of Presentation: 沖縄
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Synchrotron Radiation Used Fluorescent X-Ray Computed Tomography as a Nove1 Molecular Imaging (2007)
  • Author(s): N., Sunaguchi・Q.K., Huo・S., Nasukawa・N., Maikusa・T., Fukami・T., Yuasa, ・T., Takeda・J., Wu・Thet-Thet-Lwin・K., Hyodo・F.A., Dilmanian・T., Akastsuka
  • Organizer: IASTED Visualization, Imaging and Image Processing
  • Place of Presentation: Spain
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Physico-Mathematical Considerations on X-Ray Computed Tomography Based on Diffraction Enhanced Imaging (2007)
  • Author(s): T., Yuasa, ・A., Maksimenko・E., Hashimoto・T., Akatsuka・M., Ando
  • Organizer: IEEE EMBC07
  • Place of Presentation: France
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Observation of the breast cancer parts using X-ray refraction-based tomosynthesis (2007)
  • Author(s): A., Maksimenko・T. Yuasa, ・M., Ando・E., Hashimoto
  • Organizer: Computer Assisted Radiology and Surgery
  • Place of Presentation: Germany
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] In-vivo Fluorescent X-ray CT Imaging of Mouse Brain (2007)
  • Author(s): T., Takeda・J., Wu・Thet-Thet-Lwin・Q., Huo・N., Sunaguchi・T., Murakami・S., Mouri・S., Nasukawa・T. Yuasa, ・K., Hyodo・F.A., Dilmanian・M., Minami・T., Akatsuka
  • Organizer: AIP Synchrotron Radiation Instrumentation: 9th International Conference
  • Place of Presentation: Korea
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 肥大型心筋症例における心筋壁厚の定量的評価 (2007)
  • Author(s): 佐藤英典・深見忠典・呉 勁・Thet-Thet-Lwin・湯浅哲也・武田 徹・本谷秀堅・赤塚孝雄
  • Organizer: 日本医用画像工学会
  • Place of Presentation: つくば
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 全身のPET/CT画像中の腫瘍骨転移抽出 (2007)
  • Author(s): 鈴木貴士・新田修平・本谷秀堅・深見忠典・湯浅哲也・赤塚孝雄・呉 勁・武田 徹・織内 昇・遠藤啓吾・渡邉順久
  • Organizer: 日本医用画像工学会
  • Place of Presentation: つくば
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 蛍光X線CT画像におけるヨウ素濃度の定量的推定 (2007)
  • Author(s): 那須川清太・霍 慶凱・舞草伯秀・村上岳史・呉 勁・Thet-Thet-Lwin・武田 徹・湯浅哲也・兵藤一行・赤塚孝雄
  • Organizer: 日本医用画像工学会
  • Place of Presentation: つくば
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 多素子Ge半導体検出器を用いた蛍光X線CT実現可能性に関する基礎的検討 (2007)
  • Author(s): 霍 慶凱・那須川清太・舞草伯秀・呉 勁・Thet-Thet-Lwin・武田 徹・湯浅哲也・兵藤一行・赤塚孝雄
  • Organizer: 日本医用画像工学会
  • Place of Presentation: つくば
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Synchrotron Radiation Used Fluorescent X-Ray Computed Tomography as a Novel Molecular Imaging (2007)
  • Author(s): N. Sunaguchi, Q.-K. Huo, S. Nasukawa, N. Maikusa, T. Fukami, T. Yuasa, T. Takeda, J. Wu, Thet-Thet-Lwin, K. Hyodo, F. A. Dilmanian, and T. Akatsuka
  • Organizer: Proc IASTED, Visualization, Imaging and Image Processing
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Physico-Mathematical Considerations on X-Ray Computed Tomography Based on Diffraction Enhanced Imaging (2007)
  • Author(s): T. Yuasa A. Maksimenko, E. Hashimoto, T. Akatsuka, M. Ando
  • Organizer: Proc. IEEE EMBC07
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Observation of the breast cancer parts using X-ray refraction-based tomosynthesis (2007)
  • Author(s): A. Maksimenko, T. Yuasa M. Ando, and E. Hashimoto
  • Organizer: Proc. Computer Assisted Radiology and Surgery
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 2D and 3D Refraction Based X-ray Imaging Suitable for Clinical and Pathological Diagnosis (2007)
  • Author(s): M. Ando, H. Bando, Z. Chen, Y. Chikaura, C.-H. Choi, T. Endo, H. Esumi, L. Gang, E. Hashimoto, K. Hyodo, S. Ichiura, S.-H. Jheon, H.-T. Kim, J.-K. Kim, T. Kimura, C.-H. Lee, A. Maksimenko, C. Ohbayashi, S.-H. Park, D. Shimao, H. Sugiyama, J. Tang, E. Ueno, K. Yamasaki, and T. Yuasa
  • Organizer: AIP Conference Proceedings CP705, Synchrotron Radiation Instrumentation : 9th International Conference CP879
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] In-vivo Fluorescent X-ray CT Imaging of Mouse Brain (2007)
  • Author(s): T. Takeda, J. Wu, Thet-Thet-Lwin, Q. Huo, N. Sunaguchi, T. Murakami, S. Mouri, S. Nasukawa, T. Yuasa. K. Hyodo, F.A. Dilmanian, M. Minami, and T. Akatsuka
  • Organizer: AIP Conference Proceedings CP879, Synchrotron Radiation Instrumentation : 9th International Conference CP879
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Images of the Rat Bone, Lumber Vertebra and Test Phantom Using Diffraction Enhanced Imaging Technique with 20, 30, and 40 keV Synchrotron X-Rays (2007)
  • Author(s): D. V. Rao, Z. Zhong, T. Yuasa, T. Akatsuka, T. Takeda, and G. Tronba
  • Organizer: AIP Conference Proceedings CP879, Synchrotron Radiation Instrumentation : 9th International Conference CP879
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Validity of Fusion Imaging of Hamster Heart Obtained by Fluorescent and Phase-Contrast X-Ray CT with Synchrotron Radiation (2007)
  • Author(s): J. Wu, T. Takeda, Thet-Thet-Lwin, Q. Huo, N. Sunaguchi, T. Murakami, S. Mouri, S. Nasukawa, T. Fukami, T. Yuasa, K. Hyodo, H. Hontani, M. Minami, and T. Akatsuka
  • Organizer: AIP Conference Proceedings CP879, Synchrotron Radiation Instrumentation : 9th International Conference, CP879
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] High Quality Image of Biomedical Object by X-ray Refraction Based Contrast Computed Tomography (2007)
  • Author(s): E. Hashimoto, A. Maksimenko, H. Sugiyama, K. Hirano, K. Hyodo, D. Shimao, Y. Nishino, T. Ishikawa, T. Yuasa, S. Ichihara, Y. Arai and M. Ando
  • Organizer: AIP Conference Proceedings CP705, Synchrotron Radiation Instrumentation : 9th International Conference CP879
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Mathematical Details of the Refraction-based Computed Tomography (2007)
  • Author(s): A. Maksimenko, T. Yuasa, and M. Ando
  • Organizer: Proceedings of IASTED, Computer Graphics and Imaging
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Synchrotron Radiation Used Fluorescent X-Ray Computed Tomography as a Novel Molecular Imaging (2007)
  • Author(s): N. Sunaguchi, Q.-K. Huo, S. Nasukawa, N. Maikusa, T. Fukami, T. Yuasa, T. Takeda, J. Wu, Thet-Thet-Lwin, K. Hyodo, F.A. Dilmanian, and T. Akatsuka
  • Organizer: IASTED Visualization, Imaging and Image Processing
  • Place of Presentation: Spain
• [Presentation] In-vivo Fluorescent X-ray CT Imaging of Mouse Brain (2007)
  • Author(s): T. Takeda, J. Wu, Thet-Thet-Lwin, Q. Huo, N. Sunaguchi, T. Murakami, S. Mouri, S. Nasukawa, T. Yuasa, K. Hyodo, F. A. Dilmanian, M. Minami, and T. Akatsuka
  • Organizer: AIP Synchrotron Radiation Instrumentation: 9th International Confeence
  • Place of Presentation: Korea
• [Presentation] 3D Visualization of DCIS by high resolution synchrotron CT (2006)
  • Author(s): S. Ichihara, M. Ando, A. Maksimenko, H. Sugiyama, E. Hashimoto, T. Yuasa, H. Bando, E. Ueno, K. Yamazaki, C. Ohbayashi, and K. Hanioka
  • Organizer: Modern Pathology 19
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Fundamental study of subharmonic imaging using amplitude-modulated ultrasound wave (2006)
  • Author(s): N. Maikusa, T. Fukami, T. Yuasa, Y. Tamura, and T. Akatsuka
  • Organizer: IEEE International Ultrasonics Symposium
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Quantitative evaluation of heart disease by integration of MRI and SPECT images (2006)
  • Author(s): T. Fukami, W. Jin, T. T. Lwin, T. Yuasa, T. Takeda, T. Akatsuka, H. Hontani
  • Organizer: Proc. of World Congress on Medical Physics and Biomedical Engineering
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Sensitive Depiction of Biomedical Tissue by Refraction Based Computed Tomography Using Synchrotron Radiation (2006)
  • Author(s): E. Hashimoto, A. Maksimenko, H. Sugiyama, K. Hirano, K. Hyodo, D. Shimao, Y. Nishino, T. Ishikawa, T. Yuasa, and M. Ando
  • Organizer: Proc. of World Congress on Medical Physics and Biomedical Engineering(WC 2006)
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Progress in biomedical application of phase-contrast x-ray imaging and fluorescent x-ray CT (2006)
  • Author(s): T. Takeda, J. Wu, T. T. Lwin, A. Yoneyama, Y. Hirai, K. Hyodo, N. Sunaguchi, T. Yuasa, M. Minami, K. Kose, T. Akatsuka
  • Organizer: Proc. SPIE
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Fusion imaging of fluorescent and phase-contrast x-ray computed tomography using synchrotron radiation in medical biology (2006)
  • Author(s): J. Wu, T. Takeda, T. T. Lwin N. Sunaguchi, T. Yuasa, M. Minami, T. Akatsuka
  • Organizer: Proc. SPIE
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Spatial Resolution Effect in Myocardinal Fatty Acid Metabolic Image in Fluorescent X-ray CT (2006)
  • Author(s): T. Takeda, J. Wu, Thet-Thet-twin, N. Sunaguchi, T. Yuasa, F.A. Dilmanian, M. Minami, and T. Akatsuka
  • Organizer: Proc. 12th World Congress on Heart Disease
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] First attempt of the medical application of the refraction-based computed tomography (2006)
  • Author(s): A. Maksimenko, E. Hashimoto, M. Ando, H. Sugiyama, and T. Yuasa
  • Organizer: Proc. SPIE
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Application of x-ray computed tomography based on the refraction contrast to biomedicine (2006)
  • Author(s): E. Hashimoto, A. Maksimenko, H. Sugiyama, K. Hyodo, D. Shimao, T. Yuasa, Y. Nishino, T. Ishikawa, K. Mori, Y. Arai, K. Hirano, and M. Ando
  • Organizer: Proc. SPIE
  • Description: 「研究成果報告書概要(欧文)」より