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Target-tracking and self-referenced magnetic resonance thermometry for focused ultrasound treatment

Research Project

Project/Area Number 18500351
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionTokai University

Principal Investigator

KAGAYAKI Kuroda  Tokai University, 情報理工学部, 准教授 (70205243)

Co-Investigator(Kenkyū-buntansha) 熊本 悦子  神戸大学, 学術情報基盤センター, 准教授 (00221383)
村上 卓道  近畿大学, 医学部, 教授 (20252653)
Co-Investigator(Renkei-kenkyūsha) 村上 卓道  近畿大学, 医学部, 教授 (20252653)
熊本 悦子  神戸大学, 情報教育センター, 准教授 (00221383)
Project Period (FY) 2006 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥630,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2006: ¥1,300,000 (Direct Cost: ¥1,300,000)
Keywords(A)医用・生体画像 / MRI / 温度 / 集束超音波 / 自己参照 / 計測 / 呼吸 / 移動 / 肝臓 / トラッキング
Research Abstract

肝臓のように呼吸によって動く腹腔臓器に対する集束超音波治療とその際の非侵襲温度モニタリングを行なうために磁気共鳴画像化(MRI)を用いた方法を検討した. 肝臓門脈の断面像の変位から肝組織の動き・変形を実測し, 加温目標点を追尾する方法を提案した.複素磁気共鳴信号の位相から温度分布を求める際の, 画像引き算過程を排除した方法(自己参照法)と組み合わせ, 肝のMRIガイド下集束超音波治療の要素技術を確立した

Report

(4 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (53 results)

All 2009 2008 2007 2006

All Journal Article (12 results) (of which Peer Reviewed: 2 results) Presentation (35 results) Book (5 results) Patent(Industrial Property Rights) (1 results) (of which Overseas: 1 results)

  • [Journal Article] 自己参照法による温度分布画像化における信号処理.2007

    • Author(s)
      国領大介, 貝原俊也, 熊本悦子, 藤井進, 岡田篤哉, Bilgin Keserci, 黒田輝
    • Journal Title

      日本磁気共鳴医学会雑誌 27(1)

      Pages: 1-12

    • NAID

      10018885003

    • Related Report
      2008 Final Research Report
  • [Journal Article] 腹腔臓器のMRガイド下集束超音波治療のための温度分布ならびに臓器移動・変形量の計測.2007

    • Author(s)
      國領大介, 貝原俊也, 熊本悦子, 藤井進, 黒田輝.
    • Journal Title

      神戸大学大学院自然科学研究科紀要 25-B

      Pages: 11-20

    • NAID

      110006207598

    • Related Report
      2008 Final Research Report
  • [Journal Article] Role of Magnetic Resonance Imaging in Guiding Thermal Therapies : A Brief Technical Review.2007

    • Author(s)
      Kuroda K.
    • Journal Title

      Technical Review. 23(2)

      Pages: 71-84

    • NAID

      10029676856

    • Related Report
      2008 Final Research Report
  • [Journal Article] A Target Tracking Technique for Use with Noninvasive Magnetic Resonance Self-reference Thermometry with Focused Ultrasound Surgery.2007

    • Author(s)
      Kuroda K, Kokuryo D, Kumamoto E, Rojas J, Okada A, Murakami T.
    • Journal Title

      Thermal Medicine 3(4)

      Pages: 181-193

    • NAID

      10029677237

    • Related Report
      2008 Final Research Report
  • [Journal Article] Role of Magnetic Resonance Imaging in Guiding Thermal Therapies:A Brief Technical Review2007

    • Author(s)
      Kuroda K
    • Journal Title

      Thermal Medicine 23(2)

      Pages: 71-84

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ATarget Tracking Technique for Use with Noninvasive Magnetic Resonance Self-reference Thermometry with Focused Ultrasound Surgery,2007;:.2007

    • Author(s)
      Kuroda K, Kokuryo D, Kumamoto E, Rojas J, Okada A, Murakami T
    • Journal Title

      Thermal Medicine 23(4)

      Pages: 181-193

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 自己参照法による温度分布画像化における信号処理2007

    • Author(s)
      国領大介(大学院生)
    • Journal Title

      日本磁気共鳴医学会雑誌 27(1)

      Pages: 1-12

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 腹腔臓器のMRガイド下集束超音波治療のための温度分布ならびに臓器移動・変形量の計測2007

    • Author(s)
      国領大介(大学院生)
    • Journal Title

      神戸大学大学院自然科学研究科紀要 25-B

      Pages: 11-20

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Optimization of Self-reference Thermometry using Complex Field Estimation.2006

    • Author(s)
      Kuroda K, Kokuryo D, Kumamoto E, Suzuki K, Matsuoka Y, Keserci B.
    • Journal Title

      Magn Reson Med 56(4)

      Pages: 835-843

    • Related Report
      2008 Final Research Report
  • [Journal Article] Quasi Real-Time Feedback Control System for Liver Thermal Ablations based upon Self-Referenced Temperature Imaging.2006

    • Author(s)
      Keserci B, Kokuryo D, Suzuki K, Kumamoto E, Okada A, Khankan AA, Kuroda K.
    • Journal Title

      Eur J Radiol 59(2)

      Pages: 175-182

    • Related Report
      2008 Final Research Report
  • [Journal Article] Optimization of Self-reference Thermometry using Complex Field Estimation2006

    • Author(s)
      Kuroda K
    • Journal Title

      Magn Reson Med 56(4)

      Pages: 835-843

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Quasi Real-Time Feedback Control System for Liver Thermal Ablations based upon Self-Referenced Temperature Imaging2006

    • Author(s)
      Keserci B(企業協力者)
    • Journal Title

      Eur J Radiol 59(2)

      Pages: 175-82

    • Related Report
      2006 Annual Research Report
  • [Presentation] hree Dimensional Liver Motion Tracking Based on Vessel Structure Information for MRgFUS(p. 3293)2009

    • Author(s)
      Kumamoto E, Takao Y, Kokuryo D, Okada A, Murakami T, Kaihara T, Kuroda K
    • Organizer
      Proc 17th Annual Meeting ISMRM
    • Place of Presentation
      Honolulu
    • Related Report
      2008 Final Research Report
  • [Presentation] Effect of different fatty acid components in imaging temperature of adiposetissues2008

    • Author(s)
      Kuroda K, Obara M, Van Cauteren MV
    • Organizer
      Proc 1st MRgFUS International Symposium
    • Place of Presentation
      ヒルトンホテル・マクリーン・タイソンズコーナー(アメリカ合衆国バージニア州マクリーン)
    • Year and Date
      2008-10-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] . 磁気共鳴を用いた非侵襲温度分布画像計測の高度化 : 乳がん治療モニタのための脂肪温度計測法の検討2008

    • Author(s)
      黒田 輝, 小原 真, Van Cauteren M
    • Organizer
      Thermal Medicine ; 24 Supplment : 56
    • Place of Presentation
      中部大学名古屋キャンパス(名古屋市鶴舞)
    • Year and Date
      2008-09-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] 脂質各成分の緩和時間の温度依存性とその温度分布画像化への応用2008

    • Author(s)
      黒田 輝, 小原 真, Van Cauteren M
    • Organizer
      日本磁気共鳴医学会雑誌 ; 28 Supplment : 240
    • Place of Presentation
      旭川市民文化会館(北海道旭川市)
    • Year and Date
      2008-09-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] M R Iによる生体内温度分布の非侵襲画像計測2008

    • Author(s)
      黒田 輝
    • Organizer
      第126回 温度計測部会講演会-健康・安全・衛生に役立つ温度計測-
    • Place of Presentation
      太陽日酸(株)本社
    • Year and Date
      2008-07-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] Moving-organ Thermal MRI for Liver FUS based on Filtered Venography and Self-reference Techniques2008

    • Author(s)
      Kuroda K, Kokuryo D, Kumamoto E, Okada A, Murakami T
    • Organizer
      Insightec-BWH/HMS Symposium on Focused Ultrasound in Moving Organs
    • Place of Presentation
      ハーバード大学医学部(アメリカ合衆国ボストン)
    • Year and Date
      2008-05-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] Hot Spot Tracking for Focused Ultrasound Surgery of Liver Using Filtered Venography.2008

    • Author(s)
      Kokuryo D, Kumamoto E, Okada A, Murakami T, Fujii S, KaiharaT, Kuroda K
    • Organizer
      Proc 16 th Annual Meeging ISMRM, Toronto2008 : p. 1229.
    • Place of Presentation
      ベルリンメッセ国際会議場(ドイツ連邦共和国, ベルリン)
    • Year and Date
      2008-05-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] Optimization of Motion Sensitized Driven Equilibrium (MSDE)Preparation Scheme for Multi Contrast 3D Vessel Wall Imaging at 3.0T2008

    • Author(s)
      Obara M, Honda M, Nozaki R, Van Cauteren M, Kuroda K.
    • Organizer
      Proc 16th Annual Meeting ISMRM, Toronto2008:2842.
    • Place of Presentation
      ベルリンメッセ国際会議場(ドイツ連邦共和国, ベルリン)
    • Year and Date
      2008-05-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] Target-Tracking Thermometry for Focused Ultrasound Therapy of Liver based on Filtered Venography and Self-reference Techniques2008

    • Author(s)
      Kuroda K, Kokuryo D, Kumamoto E, Okada A, T Murakami
    • Organizer
      Proc 10th International Congress on HyperthermicOncology ; 1:29.
    • Place of Presentation
      ミュンヘン大学(ドイツ連邦共和国ミュンヘン)
    • Year and Date
      2008-04-11
    • Related Report
      2008 Annual Research Report
  • [Presentation] Target-Tracking Thermometry for Focused Ultrasound Therapy of Liver based on Filtered Venography and Self-reference Techniques2008

    • Author(s)
      Kuroda K, Kokuryo D, Kumamoto E, Okada A, Murakami T.
    • Organizer
      Proc 10th International Congress on Hyperthermic Oncology
    • Year and Date
      2008-01-29
    • Related Report
      2008 Final Research Report
  • [Presentation] Effect of different fatty acid components in imaging temperature of adipose tissues2008

    • Author(s)
      Kuroda K, Obara M, Cauteren Marc Van.
    • Organizer
      Proc 1st MRgFUS International Symposium
    • Related Report
      2008 Final Research Report
  • [Presentation] Hot Spot Tracking for Focused Ultrasound Surgery of Liver Using Filtered Venography.(1229)2008

    • Author(s)
      Kokuryo D, Kumamoto E, Okada A, Murakami T, Fujii S, Kaihara T, Kuroda K.
    • Organizer
      Proc 16 th Annual Meeging ISMRM
    • Place of Presentation
      Toronto
    • Related Report
      2008 Final Research Report
  • [Presentation] Moving-organ Thermal MRI for Liver FUS based on Filtered Venography and Self-reference Techniques2008

    • Author(s)
      Kuroda K, Kokuryo D, Kumamoto E, Okada A, Murakami T
    • Organizer
      Insightec-BWH/HMS Symposium on
    • Place of Presentation
      Focused Ultrasound in Moving Organs
    • Related Report
      2008 Final Research Report
  • [Presentation] 脂質各成分の緩和時間の温度依存性とその温度分布画像化への応用.2008

    • Author(s)
      黒田輝, 小原真, Cauteren MV
    • Organizer
      日本磁気共鳴医学会雑誌 2008 ; 28 Supplment : 240.
    • Related Report
      2008 Final Research Report
  • [Presentation] 磁気共鳴を用いた非侵襲温度分布画像計測の高度化 : 乳がん治療モニタのための脂肪温度計測法の検討2008

    • Author(s)
      黒田輝, 小原真, Cauteren MV.
    • Organizer
      Thermal Medicine 2008 ; 24 Supplment : 56.
    • Related Report
      2008 Final Research Report
  • [Presentation] MRIによる生体内温度分布の非侵襲画像計測.2008

    • Author(s)
      黒田輝
    • Organizer
      第126回 温度計測部会講演会-健康・安全・衛生に役立つ温度計測-資料
    • Related Report
      2008 Final Research Report
  • [Presentation] A.Motion analysis and target tracking for focused ultrasound surgery of liver using magnetic resonance filtered venography2007

    • Author(s)
      Kuroda K
    • Organizer
      Proc The 19th International Conference of Society for Medical Innovation and Technology(SMIT)2007:p.270
    • Place of Presentation
      Sendai,Japan
    • Year and Date
      2007-11-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] 脂質MR信号の温度依存性に関する基礎検討.,2007

    • Author(s)
      黒田 輝
    • Organizer
      第35回日本磁気共鳴医学会大会講演抄録集(日本磁気共鳴医学会雑誌 2007;27suppl:440)
    • Place of Presentation
      神戸市
    • Year and Date
      2007-09-29
    • Related Report
      2007 Annual Research Report
  • [Presentation] 腹腔臓器に対するMRガイド下集束超音波治療のための照射位置推定の検討2007

    • Author(s)
      国領 大介(大学院生)
    • Organizer
      第35回日本磁気共鳴医学会大会講演抄録集(日本磁気共鳴医学会雑誌 2007;27suppl:430)
    • Place of Presentation
      神戸市
    • Year and Date
      2007-09-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] Technical Developments for Interventional MR.2007

    • Author(s)
      Kuroda K
    • Organizer
      Proc Joint JSPS-SNSF Seminar on Computer-Aided Surgery 2007:65-66
    • Place of Presentation
      Osaka,Japan
    • Year and Date
      2007-09-24
    • Related Report
      2007 Annual Research Report
  • [Presentation] 集束超音波治療のための磁気共鳴による非侵襲・自己参照型温度分布画像化法2007

    • Author(s)
      黒田 輝
    • Organizer
      日本ハイパーサーミア学会第24回大会抄録集(Thermal Medicine 2007;23 suppl:68)
    • Place of Presentation
      前橋市
    • Year and Date
      2007-09-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] 磁気共鳴による非侵襲・自己参照型温度分布画像化法の実用化2007

    • Author(s)
      黒田 輝
    • Organizer
      日本ハイパーサーミア学会第24回大会抄録集(Thermal Medicine 2007;23 suppl:101)
    • Place of Presentation
      前橋市
    • Year and Date
      2007-09-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] A Method for Target Tracking in Focused Ultrasound Surgery of Liver using Magnetic Resonance Filtered Venography2007

    • Author(s)
      KokUlyo D(大学院生)
    • Organizer
      Proc 29th Annual Int Conf IEEE EMBS, Lyon 2007:2614-2617.
    • Place of Presentation
      Lyon,France
    • Year and Date
      2007-08-24
    • Related Report
      2007 Annual Research Report
  • [Presentation] Technical Developments for Interventional MR(65-66)2007

    • Author(s)
      Kuroda K.
    • Organizer
      Proc Joint JSPS-SNSF Seminar on Computer-Aided Surgery
    • Related Report
      2008 Final Research Report
  • [Presentation] Motion analysis and target tracking for focused ultrasound surgery of liver using magnetic resonance filtered venography.(270)2007

    • Author(s)
      Kuroda K, Kokuryo D, Kumamoto E, Jonathan R, Keserci B, Murakami T, Okada A.
    • Organizer
      Proc The 19th International Conference of Society for Medical Innovation and Technology (SMIT)
    • Related Report
      2008 Final Research Report
  • [Presentation] A Method for Target Tracking in Focused Ultrasound Surgery of Liver using Magnetic Resonance Filtered Venography.(2614-2617)2007

    • Author(s)
      Kokuryo D, Kaihara T, Kumamoto E, Fujii S, Kuroda K.
    • Organizer
      Proc 29th Annual Int Conf IEEE EMBS
    • Place of Presentation
      Lyon
    • Related Report
      2008 Final Research Report
  • [Presentation] 脂質MR信号の温度依存性に関する基礎検討2007

    • Author(s)
      黒田輝, ロハス・ジョナタン, 国領大介, 熊本悦子.
    • Organizer
      第35回日本磁気共鳴医学会大会, 日本磁気共鳴医学会雑誌 2007 ; 27 suppl : 440
    • Place of Presentation
      神戸ポートピアホテル, 神戸市中央区(講演抄録集)
    • Related Report
      2008 Final Research Report
  • [Presentation] 腹腔臓器に対するMRガイド下集束超音波治療のための照射位置推定の検討.2007

    • Author(s)
      国領大介, 黒田輝, Bilgin Keserci, 岡田篤哉, 藤井進, 熊本悦子, 貝原俊也
    • Organizer
      第35回日本磁気共鳴医学会大会, 日本磁気共鳴医学会雑誌 2007 ; 27 suppl : 430.
    • Place of Presentation
      神戸ポートピアホテル, 神戸市中央区(講演抄録集)
    • Related Report
      2008 Final Research Report
  • [Presentation] 集束超音波治療のための磁気共鳴による非侵襲・自己参照型温度分布画像化法.2007

    • Author(s)
      黒田輝, 国領大介, 熊本悦子, ロハスジョナタン, ビルギンケセルジ, 岡田篤哉, 村上卓道
    • Organizer
      日本ハイパーサーミア学会第24回大会, Thermal Medicine 2007 ; 23 suppl : 68.
    • Place of Presentation
      前橋テルサ, 群馬県前橋市(抄録集)
    • Related Report
      2008 Final Research Report
  • [Presentation] 磁気共鳴による非侵襲・自己参照型温度分布画像化法の実用化.2007

    • Author(s)
      黒田輝, 国領大介, 熊本悦子, ロハスジョナタン, 岡田篤哉, 村上卓道
    • Organizer
      日本ハイパーサーミア学会第24回大会, Thermal Medicine 2007 ; 23 suppl : 101.
    • Place of Presentation
      前橋テルサ, 群馬県前橋市(抄録集)
    • Related Report
      2008 Final Research Report
  • [Presentation] MR Thermometry for Focused Ultrasound Surgery.(p 38.)2006

    • Author(s)
      Kuroda K, Kokuryo D, Kumamoto E, Jonathan R, Keserci B, Okada A
    • Organizer
      Proc 4th Asian Congress of Hyperthermic Oncology (ACHO) and 23th Japanese Cogress of Hyperthermic Concology (JSHO)
    • Place of Presentation
      Nara, Jpn J Hyperthermic Oncol
    • Related Report
      2008 Final Research Report
  • [Presentation] Optimization of the Self-reference Thermometry using Isolated Regions for Complex Signal Estimation(p 198.)2006

    • Author(s)
      Kokuryo D, Kuroda K, Kumamoto E, Keserci B, Okada A, Kaihara T, Fujii S.
    • Organizer
      Proc 14th Annual Meeting ISMRM
    • Place of Presentation
      Seattle
    • Related Report
      2008 Final Research Report
  • [Presentation] An Electromagnetic Model for Cool-tip RF Needle Artifacts in Magnetic Resonance Imaging.(p 141.)2006

    • Author(s)
      Keserci B, Kumamoto E, Kuroda K.
    • Organizer
      Proc 14th Annual Meeting ISMRM 2006
    • Place of Presentation
      Seattle
    • Related Report
      2008 Final Research Report
  • [Presentation] 血管マーカーを用いた肝臓の呼吸性移動・変形解析.2006

    • Author(s)
      国領大介, 黒田輝, Keserci B, 岡田篤哉, 熊本悦子, 藤井進, 貝原俊也
    • Organizer
      第34回日本磁気共鳴医学会大会講演抄録集, 日本磁気共鳴医学会雑誌2006
    • Place of Presentation
      つくば国際会議場, 茨城県つくば市
    • Related Report
      2008 Final Research Report
  • [Presentation] MRIによる生体内温度分布の非侵襲画像化 : 腹腔臓器を対象とした治療部位追尾と自己参照型温度分布画像化2006

    • Author(s)
      黒田輝, 国領大介, Keserci B, 岡田篤哉, 熊本悦子
    • Organizer
      第33回日本低温医学会総会
    • Place of Presentation
      東京(招待講演)
    • Related Report
      2008 Final Research Report
  • [Book] 15.1.6 非侵襲温度計測を基にした熱物性計測 : 核磁気共鳴を応用した非侵襲温度計測, 15.1 生体物質, C. 15 生体・バイオ・医学.(日本熱物性学会, 新編 熱物性ハンドブック)2008

    • Author(s)
      黒田輝
    • Publisher
      東京 : 養賢堂
    • Related Report
      2008 Final Research Report
  • [Book] 第4章11節非侵襲的測温技術(MRI・超音波・電磁波)(日本ハイパーサーミア学会, editor. ハイパーサーミア がん温熱療法ガイドブック)2008

    • Author(s)
      黒田輝
    • Publisher
      東京 : 神陵文庫
    • Related Report
      2008 Final Research Report
  • [Book] 15.1.6非侵襲温度計測を基にした熱物性計測 : 核磁気共鳴を応用した非侵襲温度計測, 15.1生体物質, C. 15生体・バイオ・医学, 日本熱物性学会編(編集委員長長島昭), 新編 熱物性ハンドブック2008

    • Author(s)
      黒田 輝
    • Total Pages
      4
    • Publisher
      養賢堂
    • Related Report
      2008 Annual Research Report
  • [Book] 第1章MRIを用いる形態, 機能, 代謝の可視化, 第10節MRI法の新しい展開, 4. 温度の可視化, MRIによる体内温度分布の非侵襲画像化技術. 非侵襲・可視化技術ハンドブック-ナノ・バイオ・医療から情報システムまで(小川誠二)2007

    • Author(s)
      黒田輝
    • Publisher
      東京 : エヌ・ティー・エス
    • Related Report
      2008 Final Research Report
  • [Book] 第1章 MRIを用いる形態,機能,代謝の可視化,第10節 MRI法の新しい展開,4.温度の可視化,MRI法による体内温度分布の非侵襲画像化技術,非侵襲・可視化技術ハンドブック-ナノ・バイオ・医療から情報システムまで-2007

    • Author(s)
      黒田 輝
    • Total Pages
      3
    • Publisher
      エヌ・ティー・エス
    • Related Report
      2006 Annual Research Report
  • [Patent(Industrial Property Rights)] Self-referencing/ Motion-tracking noninvasive internal temperature distribution measurement method and apparatus using magnetic resonance tomographic imaging technique2009

    • Inventor(s)
      Kuroda K
    • Industrial Property Rights Holder
      US Patent
    • Acquisition Date
      2009-03-17
    • Related Report
      2008 Final Research Report
    • Overseas

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Published: 2006-04-01   Modified: 2016-04-21  

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