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Analysis for sleep apnea syndrome using thoracic impedance plethysmography during sleep and its application to health science

Research Project

Project/Area Number 18500540
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied health science
Research InstitutionToyohashi University of Technology

Principal Investigator

YASUDA Yoshifumi  Toyohashi University of Technology, 体育・保健センター, 教授 (70126952)

Co-Investigator(Kenkyū-buntansha) HORIHATA Satoshi  日本大学, 松戸歯学部, 准教授 (20238801)
Project Period (FY) 2006 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,230,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2007: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2006: ¥1,800,000 (Direct Cost: ¥1,800,000)
Keywords睡眠時無呼吸症候群 / インピーダンス計測 / 動脈血酸素飽和度 / 胸部インピーダンス / 睡眠時呼吸障害 / 動脈血酸飽和度(Sp02) / 心拍変動 / 眠気 / 瞬目 / 眼瞼運動 / 近赤外分光法 / 静脈血酸素飽和度 / 閉塞性無呼吸 / 伏臥寝 / 近赤外分光法(NIRS) / 静脈阻止法
Research Abstract

本研究では、胸部インピーダンス法および近赤外分光装置を用い睡眠時の呼吸動態および低酸素化を計測する簡易なシステムを開発した。呼吸計測に関しては胸部インピーダンス信号から心拍同調成分を選択的に分離し、呼吸に由来する成分を抽出する方法を完成させた。この信号と動脈血酸素飽和度、心拍数の計時的変化から睡眠時の無呼吸・低呼吸を判別した。その結果、睡眠障害を自覚していない健康な若者においても、睡眠中の無呼吸・低呼吸、さらには動脈血酸素飽和度の有意な低下が観察された。

Report

(4 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (32 results)

All 2009 2008 2007 2006

All Journal Article (16 results) (of which Peer Reviewed: 6 results) Presentation (16 results)

  • [Journal Article] Influence of low frequency noise in adaptive estimation using the LMS algorithm.2009

    • Author(s)
      Brito D. S., Aguiar E., Lucena F., Freire R. C. S., Yasuda Y., Barros A. K.
    • Journal Title

      Signal Processing 89

      Pages: 933-940

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of low frequency noise in adaptive estimation using the LMS algorithm2008

    • Author(s)
      Brito DS, Aguiar E, Lucena F, Freire RCS, Yasuda Y, Barros AK
    • Journal Title

      Signal Processing 89

      Pages: 933-940

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Muscle strength estimation using musculo-skeletal model for upper arm rehabilitation2008

    • Author(s)
      Okada T, Imamura T, Miyoshi T, Terashima K, Yasuda Y, Suzuki T
    • Journal Title

      J. Robotics Mechatro 20

      Pages: 863-871

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 動脈及び静脈血酸素飽和度の測定可能な近赤外分光装置の開発とその臨床応用2008

    • Author(s)
      安田好文, 庭山雅嗣, 穂積直裕, 小池茂文, 石黒稔道, 竹上俊次
    • Journal Title

      東海産業技術振興財団研究完了報告書 51

      Pages: 21-26

    • Related Report
      2008 Final Research Report
  • [Journal Article] 睡眠時の姿勢が呼吸パターンおよび呼吸筋活動に及ぼす影響2008

    • Author(s)
      安田好文, 鈴木拓央, 寺嶋一彦, 鈴木直也, 小池茂文
    • Journal Title

      豊橋技術科学大学人文社会工学系紀要 30

      Pages: 69-80

    • NAID

      110006978123

    • Related Report
      2008 Final Research Report
  • [Journal Article] Muscle strength estimation using musculo-skeletal model for upper limb rehabilitation.2008

    • Author(s)
      Okada T., Imamura T., Miyoshi T., Terashima K., Yasuda Y., Suzuki T.
    • Journal Title

      Journal of Robotics and Mechatronics 20

      Pages: 863-871

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 動脈及び静脈血酸素飽和度の測定可能な近赤外分光装置の開発とその臨床応用2008

    • Author(s)
      安田好文, 庭山雅嗣, 穂積直裕, 小池茂文, 石黒稔道, 竹上俊次
    • Journal Title

      東海産業技術振興財団助成研究完了報告書 51

      Pages: 21-26

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 睡眠時の姿勢が呼吸パターンおよび呼吸筋活動に及ぼす影響2008

    • Author(s)
      安田 好文、鈴木 拓央、寺島 一彦、鈴木 直也、小池 茂文
    • Journal Title

      豊橋技術科学大学人文・社会工学系紀要 30

      Pages: 69-80

    • NAID

      110006978123

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Accurate measurement of venous oxygen saturation by near infrared spectroscopy2007

    • Author(s)
      Yasuda Y, Yasuda Y, Sekiguchi Y, Horihata S, Nagao M
    • Journal Title

      Proceeding of the Fifth Symposium on Intelligent Human Sensing

      Pages: 175-178

    • Related Report
      2008 Final Research Report
  • [Journal Article] Accurate measurement of venous oxygen saturation by near infrared spectroscopy in human limbs.2007

    • Author(s)
      Yasuda Y., Yasuda Y.Jr., Sekiguchi Y., Horihata S., Nagao M.
    • Journal Title

      Proceedings of The Fifth Symposium on Intelligent Human Sensing

      Pages: 175-178

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 近赤外分光法を用いた静脈血酸素飽和度の測定2007

    • Author(s)
      安田吉輝, 安田好文, 庭山雅嗣
    • Journal Title

      第11回日本体力医学会界東海地方会学術集会抄録集 11

      Pages: 19-19

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Modified scaled Fourier combiner in thoracic impedance cardiography2006

    • Author(s)
      Ishiguro T, Umezu A, Yasuda Y, Horihata S, Barros AK
    • Journal Title

      Comp.Biol.Med 36

      Pages: 997-1013

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Time series data mining for multimodal bio-signal data2006

    • Author(s)
      Aono M, Sekiguchi Y, Yasuda Y, Suzuki N, Seki Y
    • Journal Title

      Int.J.Comp. Science Network Security 6

      Pages: 1-9

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Modified scaled Fourier linear combiner in thoracic impedance cardiography.2006

    • Author(s)
      Ishiguro T., Umezu A., Yasuda Y., Horihata S., Barros A.K.
    • Journal Title

      Computers in Biology and Medicine 36

      Pages: 997-1013

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Time series data mining for multimodal bio-signal data.2006

    • Author(s)
      Aono M., Sekiguchi Y., Yasuda Y., Suzuki N., Seki Y.
    • Journal Title

      International Journal of Computer Science and Network Security 6

      Pages: 1-9

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 眠気出現期の瞬きの定量的観察2006

    • Author(s)
      関口雄介, 鈴木直也, 山本勝徳, 小池茂文, 安田好文
    • Journal Title

      日本睡眠学会第31回定期学術集会抄録集 31

      Pages: 157-157

    • Related Report
      2006 Annual Research Report
  • [Presentation] 高酸素負荷が最大下運動時の呼吸・循環機能に及ぼす影響2009

    • Author(s)
      伊藤智式, 安田好文, 城島健彦
    • Organizer
      第13回日本体力医学会東海地方会
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Independent component analysis using wavelet transform and its application to biological signals2008

    • Author(s)
      Horihata S, Zhang Z, Toda H, Imamura T, Miyake T, Yasuda Y
    • Organizer
      2008 International Conference on Wavelet Analysis and Pattern Recognition
    • Related Report
      2008 Final Research Report
  • [Presentation] 睡眠姿勢が呼吸パターンおよび呼吸筋活動に及ぼす影響2008

    • Author(s)
      安田好文, 鈴木拓央, 鈴木直也, 関口雄祐, 山本勝徳, 小池茂文
    • Organizer
      日本睡眠学会第33回定期学術集会
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Independent component analysis using wavelet transform and its application to biological signals.2008

    • Author(s)
      Horihata S., Zhang Z., Enomoto T., Toda H., Imamura T., Miyake T., Yasuda Y.
    • Organizer
      2008 International Conference on Wavelet Analysis and Pattern Recognition
    • Place of Presentation
      Hong Kong
    • Related Report
      2008 Annual Research Report
  • [Presentation] 眼球運動情報を利用したドライバの眠気検出法に関する研究2007

    • Author(s)
      鈴木 直也、三宅 哲夫、安田 好文、章 忠、今村 孝
    • Organizer
      自動車技術会秋季学術講演会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2007-10-19
    • Related Report
      2007 Annual Research Report
  • [Presentation] 表面筋電信号と骨格リンク機構モデルを用いた上腕筋力の評価2007

    • Author(s)
      岡田 達弥、鈴木 拓央、三好 孝典、寺嶋 一彦、今村 孝、安田 好文
    • Organizer
      福祉工学シンポジウム
    • Place of Presentation
      産業技術総合研究所つくばセンター
    • Year and Date
      2007-10-03
    • Related Report
      2007 Annual Research Report
  • [Presentation] Evaluation of a compact wireless pulse oximeter.2007

    • Author(s)
      Stuban N., Santha H., Niwayama M, Yasuda Y.
    • Organizer
      6th Inter-Academia 2007
    • Place of Presentation
      アクトシティ浜松
    • Year and Date
      2007-09-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] Using two blink parameters derived from EOG to detect drowsiness.2007

    • Author(s)
      Sekiguchi Y., Suzuki N., Horihata S., Yasuda Y.
    • Organizer
      5th Congress of the World Federation of Sleep Research and Sleep Medicine Societies
    • Place of Presentation
      Cairns, Austria
    • Year and Date
      2007-09-05
    • Related Report
      2007 Annual Research Report
  • [Presentation] 眠気出現時の瞬目変化および眠気警告閾値の検討2007

    • Author(s)
      関口 雄祐、章 忠、鈴木 直也、堀畑 聡、安田 好文
    • Organizer
      2007自動車技術会春季学術講演会
    • Place of Presentation
      パシピコ横浜
    • Year and Date
      2007-05-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] 表面筋電図信号と骨格リンク機構モデルを用いた上腕筋力の評価2007

    • Author(s)
      岡田達弥, 鈴木拓央, 三好孝典, 寺嶋一彦, 今村孝, 安田好文
    • Organizer
      福祉工学シンポジウム
    • Related Report
      2008 Final Research Report
  • [Presentation] 眼球運動情報を利用したドライバの眠気検出法に関する研究2007

    • Author(s)
      鈴木直也, 三宅哲夫, 三好孝典, 寺嶋一彦, 今村孝, 安田好文
    • Organizer
      自動車技術会秋季学術講演会
    • Related Report
      2008 Final Research Report
  • [Presentation] Evaluation of a compact wireless pulse oximeter2007

    • Author(s)
      Stuban N, Santha H, Niwayama M, Yasuda Y
    • Organizer
      6^<th> Inter-Academia 2007
    • Related Report
      2008 Final Research Report
  • [Presentation] Using two blink parameters derived from EOG to detect drowsiness2007

    • Author(s)
      Sekiguchi Y, Suzuki N, Horihata S, Yasuda Y
    • Organizer
      5^<th> Congress of the World Federationof Sleep Research and Sleep Societies
    • Related Report
      2008 Final Research Report
  • [Presentation] 2007自動車技術会春季学術講演会2007

    • Author(s)
      関口雄祐、章忠、鈴木直也、堀畑聡、安田好文
    • Related Report
      2008 Final Research Report
  • [Presentation] 近赤外分光法を用いた静脈血酸素飽和度の測定2007

    • Author(s)
      安田吉輝, 安田好文, 庭山雅嗣
    • Organizer
      第11回日本体力医学会東海地方会学術集会
    • Related Report
      2008 Final Research Report
  • [Presentation] 眠気出現期の瞬きの定量的観察2006

    • Author(s)
      関口雄祐、鈴木直也、山本勝徳、小池茂文、安田好文
    • Organizer
      日本睡眠学会第31回定期学術集会
    • Related Report
      2008 Final Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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