| Project/Area Number |
18550092
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Osaka University |
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Principal Investigator |
IMADA Yasushi Osaka University, Graduate School of Engineering Science, Associate Professor (60183191)
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| Project Period (FY) |
2006 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥4,130,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2006: ¥2,700,000 (Direct Cost: ¥2,700,000)
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| Keywords | organocatalysts / flavin catalysts / aerobic oxidations / environmentally friendry / hydrogenation / diimide / dendrimers / gold nanoparticles / フラビンン触媒 / フラビン触媒 / ヒドラジン / グリーンケミストリー |
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| Research Abstract |
Organocatalytic aerobic oxidation is one of the most attractive methods because of availability and safety of molecular oxygen and organocatalysts. In this project, the author developed highly selective and environmentally friendly methods for oxidation of heteroatom compounds as well as hydrogenation of olefins based on the flavin-promoted activation of molecular oxygen.
1. Hydrazine was oxidized readily by flavinium cation-ratalyzed aerobic oxidation to give diazene, which is a highly active hydrogen donor towards unsaturated bonds. Using the system, the author developed environmentally f iendly hydrogenation method for olefins without using metal catalysts and hydrogen gas.
3. Dendrimers bearing diaminopyridine core bind flavin molecules through three-point hydrogen bonding interaction to form flavin-dendrimer complexes. The compexes exhibited high catalytic performance due to the hydrohobic environment around the catalyst.
3. Dendrimers bearing diaminopyridine core bind flavin molecules through three-point hydrogen bonding interaction to fomi flavin-dendrimer complexes. The compexes exhibited high catalytic performance due to the hydrohobic environment around the catalyst.
4. Gold nanoparticles can be functionalized by flavin molecules. The flavin-functionalized gold nanoparticles can be used as catalysts for aerobic oxidation of sulfides and aerobic hydrogenation of of efins.
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