• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Studies on Complex Formation Mechanisms of Chitosan Based on Synchrotron Fiber Diffication

Research Project

Project/Area Number 18550104
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Polymer chemistry
Research InstitutionTokyo University of Agriculture and Technology

Principal Investigator

NOGUCHI Keiichi  Tokyo University of Agriculture and Technology, Instrumentation Analysis Center, Associate Professor (00251588)

Project Period (FY) 2006 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥4,220,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥420,000)
Fiscal Year 2007: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2006: ¥2,400,000 (Direct Cost: ¥2,400,000)
KeywordsX-ray Diffraction / Crystal Structure / Synchrotron Radiation / Interaction / Hydrogen Bond / Polysaccharide / Chitosan / Fiber Diffraction / 結晶解析
Research Abstract

In order to elucidate the intermolecular interactions involved in complex formation of chitosan with hydrogen halides, crystal structures of chitosan complexes with HBr and HI were analyzed based on synchrotron X-ray fiber diffraction data (BL40B2, SPring-8, Hyogo, Japan). Both crystals are isomorphous and belong to the monoclinic space group P2_1. The unit cell constants are a=9.299(9), b=9.504(8), c(fiber axis)=10.41(1) A and β= 106.93(8)°, and a=9.46(2), b=9.79(2), c(fiber axis)=10.33(2) A and β=105.1(2)° for HBr and HI complexes, respectively. The final packing models were obtained by the linked-atom least-squares refinement, which gave R-factors of 0.192 for HBr complex (93 observed spots) and 0.193 for HI complex (44 observed spots). The halide ions are aligned along the c-axis at intervals of about 5A and are surrounded by four polymer chains. In an asymmetric unit, there are two halide ions. One ion accepts three hydrogen bonds from NH3^+ groups (N2 nitrogen). The other one participates in one hydrogen bond from N2 and two hydrogen bonds from primary hydroxyl groups (O6 oxygen). In addition, the chitosan chains are linked by N-H…O and C-H…O hydrogen bonds along the b-axis direction. The crystal structure of the hydrated form of chitosan was reanalyzed using synchrotron X-ray fiber diffraction data (BL38B1, Spring-8). The chitosan chains make sheet structures parallel to the bc-plane and these sheets stack along the a-axis. Water molecules form columns between these sheets. The sites of the halide ions in the complex crystals are similar to those of the water molecules in the hydrated form. It was suggested that the columnar structure of water in the hydrated form plays an important role for the complex formation.

Report

(3 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • Research Products

    (18 results)

All 2007 2006

All Journal Article (12 results) (of which Peer Reviewed: 5 results) Presentation (6 results)

  • [Journal Article] WinLALS series for Helical Polymers running on Windows PCs2007

    • Author(s)
      Kenji Okada, et. al.
    • Journal Title

      Z. Kristallogr. 222

      Pages: 306-307

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] WinLALS series for Helical Polymers running on Windows PCs2007

    • Author(s)
      Kenji, Okada, Ploenpit, Boochathum, Keiichi, Noguchi, Kenji, Okuyama
    • Journal Title

      Z. Kristallogr 222

      Pages: 306-307

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Win LALS series for Helical Polymers running on Windows PCs2007

    • Author(s)
      Kenji Okada, ら
    • Journal Title

      Z. Kristallogr. 222

      Pages: 306-307

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 1,8-Bis (4-chlorobenzoyl)-2,7-dimethoxynaphthalene2007

    • Author(s)
      Kosuke Nakaema, ら
    • Journal Title

      Acta Crystallographica Section E E63

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Crystal Structures of Chitosan/Hydrogen Hglides Complexes Based on Synchrotron X-ray Fiber Diffraction2006

    • Author(s)
      Keiichi Noguchi, et. al.
    • Journal Title

      Advances in Chitin Science and Technology

      Pages: 41-43

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 1, 6, 11, 16-tetraoxacycloeicosane-7, 10, 17, 20-tetraone2006

    • Author(s)
      Keiichi Noguchi, et. al.
    • Journal Title

      Acta Crystallographica Section C C62

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Visual Graphic Library VGLIB5 for Crystallographic Programs on Windows PCs2006

    • Author(s)
      Kenji Okada, et. al.
    • Journal Title

      Commission on Crystallogaphic Computing Newsletter 7

      Pages: 120-128

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Crystal Structures of Chitosan/Hydrogen Halides Complexes Based on Synchrotron X-ray Fiber Diffraction2006

    • Author(s)
      Keiichi, Noguchi, Masakazu, Kanenari, Amornrat, Lertworasirikul, Shingo, Yokoyama, Kenji, Okuyama, Kozo, Ogawa
    • Journal Title

      Advances in Chitin Science and Technology

      Pages: 41-43

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] 1,6,11,16-tetraoxacycloeicosane-7,10,17,20-tetraone2006

    • Author(s)
      Keiichi, Noguchi, Hidekazu, Kondo, Yasushi, Ichikawa, Junichiro, Washiyama, Kenji, Okuyama
    • Journal Title

      Acta Clystallogr C62

      Pages: 528-30

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Visual Graphic Library VGLIB5 for Crystallographic Programs on Windows PCs2006

    • Author(s)
      Kenji, Okada, Ploenpit, Boochathum, Keiichi, Noguchi, Kenji, Okuyama
    • Journal Title

      Commission on Crystallographic Computing Newsletter 7

      Pages: 120-128

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Crystal Structures of Chitosan/Hydrogen Halides Complexes Based on Synchrotron X-ray Fiber Diffraction2006

    • Author(s)
      K.Noguchi, M.Kanenari, A.Lertworasirikul, S.Yokoyama, K.Okuyama, Ogawa
    • Journal Title

      Advances in Chitin Science and Technology

      Pages: 41-43

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 1,6,11,16-tetraoxacycloeicosane-7,10,17,20-tetraone2006

    • Author(s)
      K.Noguchi, H.Kondo, Y.Ichikawa, J.Washiyama, K.Okuyama
    • Journal Title

      Acta Crystallographica Section C C62

    • Related Report
      2006 Annual Research Report
  • [Presentation] 放射光を利用した脂肪族ポリエステルの繊維結晶構造解析2007

    • Author(s)
      野口 恵一
    • Organizer
      大阪大学蛋白質研究所セミナー「放射光が拓く繊維高分子のルネッサンス」
    • Place of Presentation
      大阪大学蛋白質研究所
    • Year and Date
      2007-06-08
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Crystal Structure Analyses on Biodegradable Polyesters Based on Synchrotron Fiber Diffraction Data2007

    • Author(s)
      Keiichi, Noguchi
    • Organizer
      IPR (Institute for Protein Research) Seminar
    • Place of Presentation
      Osaka University, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Molecular Packing and Intermolecular Interactions in Chitosan/Hydrogen Halides Complexes2006

    • Author(s)
      Keiichi Noguchi
    • Organizer
      Joint Conference of the Asian Crystallographic Association and the Crystallographic of Japan
    • Place of Presentation
      Tsukuba, Japan
    • Year and Date
      2006-11-23
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Crystal Structures of Chitosan/Hydrogen Halides Complexes Based on Synchrotron X-ray Fiber Diffraction2006

    • Author(s)
      Keiichi Noguchi
    • Organizer
      7th Asia-Pacific Chitin and Chitosan Symposium
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2006-04-25
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Crystal Structures of Chitosan/Hydrogen Halides Complexes Based on Synchrotron X-ray Fiber Diffraction2006

    • Author(s)
      Keiichi, Noguchi, Masakazu, Kanenari, Amornrat, Lertworasirikul, Shingo, Yokoyama, Kenji, Okuyama, Kozo, Ogawa
    • Organizer
      7th Asia-Pacific Chitin and Chitosan Symposium(APCCS)
    • Place of Presentation
      Busan, Korea
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Molecular Packing and Intermolecular Interactions in Chitosan/Hydrogen Halides Complexes2006

    • Author(s)
      Keiichi, Noguchi, Masakazu, Kanenari, Kenji, Okuyama, Kozo, Ogawa
    • Organizer
      Joint Conference of the Asian Crystallogra-phic Association and the Crystallographic Society of Japan
    • Place of Presentation
      Tsukuba, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary

URL: 

Published: 2006-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi