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Control of internal structure of porous membranes of biodegradable polymer blends and its application to bioprocesses

Research Project

Project/Area Number 18560748
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biofunction/Bioprocess
Research InstitutionNiigata University

Principal Investigator

TANAKA Takaaki  Niigata University, 自然科学系, 准教授 (00217043)

Co-Investigator(Kenkyū-buntansha) 谷口 正之  新潟大学, 自然科学系, 教授 (00163634)
Co-Investigator(Renkei-kenkyūsha) TANIGUCHI Masayuki  新潟大学, 自然科学系, 教授 (00163634)
Project Period (FY) 2006 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,740,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥540,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2007: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2006: ¥1,400,000 (Direct Cost: ¥1,400,000)
Keywords生分解性ポリエステル / ポリマーブレンド / 相分離法 / 多孔質 / 分離膜 / 生分離性ポリエステル
Research Abstract

本研究は, 生分解性ポリマーブレンド多孔質膜の内部構造を制御して高機能化し, バイオプロセスに利用することを目的として進めた。内部構造の制御については, ポリ乳酸とポリカプロラクトンのポリマーブレンドについて種々の混合比のポリマーブレンド溶液の相分離挙動を観察し, さらに相分離法により各種生分解性ポリマーブレンド多孔質膜を作製した。バイオプロセスへの応用については分離膜への応用と生分解性ポリマーブレンド多孔質体内でのヒト肝細胞HepG2の培養を検討した。

Report

(4 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (21 results)

All 2008 2007 2006 Other

All Journal Article (10 results) (of which Peer Reviewed: 7 results) Presentation (8 results) Remarks (3 results)

  • [Journal Article] Microporous foams of polymer blends of poly(L-lactic acid) and poly(ε-caprolactone)2008

    • Author(s)
      T. Tanaka, S. Eguchi, H. Saitoh, M. Taniguchi, and D.R. Lloyd
    • Journal Title

      Desalination 234 巻

      Pages: 175-183

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 生分解性プラスチック製濾過膜の開発2008

    • Author(s)
      田中孝明
    • Journal Title

      膜 33巻(4)

      Pages: 165-172

    • NAID

      10026876305

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] ポリ乳酸の多孔質化・複合化による機能性材料の開発2008

    • Author(s)
      田中孝明, 谷口正之
    • Journal Title

      日本生物工学会誌 86巻(7)

      Pages: 346-348

    • NAID

      110006840443

    • Related Report
      2008 Final Research Report
  • [Journal Article] ポリ乳酸の多孔質化・複合化による機能性材料の開発2008

    • Author(s)
      田中孝明, 谷口正之
    • Journal Title

      日本生物工学会誌 86

      Pages: 346-348

    • NAID

      110006840443

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 生分解性プラスチック製濾過膜の開発2008

    • Author(s)
      田中孝明
    • Journal Title

      膜 33

      Pages: 165-172

    • NAID

      10026876305

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Microporous foams of polymer blends of poly (L-lactic acid) and poly (ε-caprolactone)2008

    • Author(s)
      T. Tanaka, et al.
    • Journal Title

      Desalination 234

      Pages: 175-183

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Production of laccase by membrane-surface liquid culture of Trametes versicolor using a poly(L-lactic acid) membrane2007

    • Author(s)
      T. Tanaka, S. Eguchi, T. Aoki, T. Tamura, H. Saitoh, M. Taniguchi, H. Ohara, K. Nakanishi, and D.R. Lloyd
    • Journal Title

      Biochem. Eng. J. 33巻(2)

      Pages: 188-191

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 食品微生物の膜分離に関する研究2007

    • Author(s)
      田中孝明
    • Journal Title

      日本食品工学会誌 8巻(4)

      Pages: 221-229

    • NAID

      130004039971

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 食品微生物の膜分離に関する研究2007

    • Author(s)
      田中孝明
    • Journal Title

      日本食品工学会誌 8

      Pages: 221-229

    • NAID

      130004039971

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Production of laccase by membrane-surface liquid culture of Trametes versicolor using a poly (L-lactic acid) membrane2007

    • Author(s)
      Takaaki Tanaka
    • Journal Title

      Biochemical Engineering Journal 33・2

      Pages: 188-191

    • Related Report
      2006 Annual Research Report
  • [Presentation] 生分解性プラスチック製濾過膜の開発2008

    • Author(s)
      田中孝明
    • Organizer
      日本膜学会, 依頼講演
    • Place of Presentation
      東京都新宿区
    • Year and Date
      2008-05-15
    • Related Report
      2008 Final Research Report
  • [Presentation] 生分解性プラスチック製濾過膜の開発2008

    • Author(s)
      田中孝明
    • Organizer
      日本膜学会(依頼講演)
    • Place of Presentation
      東京理科大学
    • Year and Date
      2008-05-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] ポリ乳酸の多孔質化・複合化による機能性材料の開発2007

    • Author(s)
      田中孝明, 谷口正之
    • Organizer
      日本生物工学会
    • Place of Presentation
      東広島市
    • Year and Date
      2007-09-27
    • Related Report
      2008 Final Research Report
  • [Presentation] Microporous foams of polymer blends of poly(L-lactic acid) and poly (ε-caprolactone)2007

    • Author(s)
      T. Tanaka, S. Eguchi, H. Saitoh, M. Taniguchi, and D.R. Lloyd
    • Organizer
      The Fourth Conference of Aseaninan Membrane Society
    • Place of Presentation
      台湾台北市
    • Year and Date
      2007-08-18
    • Related Report
      2008 Final Research Report
  • [Presentation] Microporous foams of polymer blends of poly (L-lactic acid) and poly (ε-caprolactone)2007

    • Author(s)
      田中孝明
    • Organizer
      The Fourth Conference of Aseanian Membrane Society
    • Place of Presentation
      Taipei
    • Year and Date
      2007-08-18
    • Related Report
      2007 Annual Research Report
  • [Presentation] 食品微生物の膜分離に関する研究2007

    • Author(s)
      田中孝明
    • Organizer
      日本食品工学会, 受賞講演奨励賞
    • Place of Presentation
      大阪府吹田市
    • Year and Date
      2007-08-03
    • Related Report
      2008 Final Research Report
  • [Presentation] Mechanical properties of microporous foams of biodegradable polyesters formed via thermally induced phase separation2006

    • Author(s)
      T. Tanaka, T. Aoki, S. Eguchi, M. Taniguchi, W. Ogawa, Y. Tanabe, and D.R. Lloyd
    • Organizer
      2006 AIChE Annual Meeting
    • Place of Presentation
      アメリカ合衆国サンフランシスコ市
    • Year and Date
      2006-11-15
    • Related Report
      2008 Final Research Report
  • [Presentation] Depth filter membranes of biodegradable polyesters2006

    • Author(s)
      T. Tanaka, T. Tsuchiya, H. Takahashi, M. Taniguchi, and D.R. Lloyd
    • Organizer
      2006 AIChE Annual Meeting
    • Place of Presentation
      アメリカ合衆国サンフランシスコ市
    • Year and Date
      2006-11-14
    • Related Report
      2008 Final Research Report
  • [Remarks]

    • URL

      http://tctanaka.eng.niigata-u.ac.jp/top_e.html

    • Related Report
      2008 Final Research Report
  • [Remarks] 田中孝明, 日本食品工学会2006年度奨励賞, 「食品微生物の膜分離に関する研究」

    • Related Report
      2008 Final Research Report
  • [Remarks]

    • URL

      http://tctanaka.eng.niigata-u.ac.jp/top_e.html

    • Related Report
      2008 Annual Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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