Broader understanding of the transduction mechanisms in insect sugar receptors : Asignal transduction pathway involving nitric oxide
| Project/Area Number |
18570068
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Animal physiology/Animal behavior
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| Research Institution | The University of Electro-Communications |
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Principal Investigator |
NAKAMURA Tadashi The University of Electro-Communications, 電気通信学部, 教授 (50217858)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Atsushi 電気通信大学, 電気通信学部, 助教 (50361829)
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| Co-Investigator(Renkei-kenkyūsha) |
OZAKI Mamiko 神戸大学, 大学院・理学研究科, 教授 (00314302)
MURATA Yoshihiro 高知医科大学, 医学部, 助教 (40377031)
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| Project Period (FY) |
2006 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,220,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥720,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2006: ¥1,100,000 (Direct Cost: ¥1,100,000)
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| Keywords | 昆虫 / 糖受容細胞 / 苦味物質受容細胞 / 情報変換機構 / 一酸化窒素 / 環状ヌクレオチド / 食欲調節機構 / 吻伸展反射 / ショウジョウバエ / アポトーシス遺伝子 / クロキンバエ / 苦味受容細胞 / GAL4 / UASシステム / 動物生理 / 化学 / セカンドメッセンジャー / 化学感覚 |
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| Research Abstract |
Relationships between NO-production and the excitation mechanisms in the taste cells and between the taste sensation and appetite regulation were investigated. NO-sensitive guanylyl cyclase (sGC) was detected and suggested to participate in the signal transduction pathways in the sugar cells, while other pathway was detected in the bitterness cells. Meanwhile it was demonstrated that the fly's aversive behavior to sucrose after their feeding sucrose in the limonene fume was due to the formation of long-term memory.
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Report
(6 results)
Research Products
(40 results)
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[Journal Article] NO-cGMP signaling pathway2007
Author(s)
Tadashi Nakamura
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Journal Title
sugar receptor neurons in the blowfly in "Frontiers in Molecular Endocrinology of Invertebrates and Vertebrates, Vol. 2", Department of Animal Sciences, School of Life Scie
Pages: 1-5
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