| Budget Amount *help |
¥3,860,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2006: ¥2,300,000 (Direct Cost: ¥2,300,000)
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| Research Abstract |
This research did the research regarding the development of such an electricity stimulation answer style drugs discharge control microchip that enables tailor-maid medicine. The element that can discharge the drugs from the electrode did production the pyrrole derivative that replaced the bipyridinium salt that fixates on a foundation by utilizing the interaction of static electricity by surface cast law or turn on the discharge drugs pair and have, after Nafion is covered on the foundation electrode and able to produce the cation nature drugs by fixating upward a foundation by an electricity chemical heavy reaction. By controlling the controlled potential electrolysis, even in either element that was produced these the discharge quantity of the drugs that is fixed able to be controlled release. On the other hand, the discharge quantity of the drugs that is fixed able to be controlled release, by controlling a/the setting potential in constant current electrolysis law. Furthermore, by
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making a/the setting current minimum it came the discharge start of the drugs that is fixed with a delay.
Next, the insulin was discharged from the drugs discharge element when it reached a/the treatment area, as I tried the discharge control of insulin while giving monitoring to a target when it combines, passes the insulin fixation element and glucose sensor for the purpose of the treatment of the diabetic. Also, make. a/the storeroom a pyramid state such that the drugs delivery utilize the technology of microinjection etc. to the foundation by using, silicon aiming at, the development of a possible element with a long time cycle and able to fill up little quantity precisely and cover the surface in the gold membrane where can prevent the corrosion by oxygen and chlorine ion etc. and overturned with silicon dioxy film to also prevent corrosion even positive pole and, the negative pole. The drugs fixate the functionability material that discharging by electricity stimulation on the positive pole of this element, the corrosiveness inside a body was investigated. Without receiving an influence at all during the solution of the component similar to living body inside as a result, without being corroded this electricity stimulation drugs discharge chip the drugs delivery were possible with a long time cycle. Less
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