| Budget Amount *help |
¥4,100,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥600,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2006: ¥1,500,000 (Direct Cost: ¥1,500,000)
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| Research Abstract |
To reveal the process of hepatoblast differentiation and hepatoblastic tissue construction, I analyzed the embryonic and fetal liver using immunohistochemical and ultrastructural methods. Hepatoblasts become to be expressed N-cadherin, a molecule in adherence junction, when they are differentiated from endodermal epithelia of foregut. And N-cadherin is detected in hepatoblasts and fetal hepatocytes throughout embryonic and fetal period. I also revealed that hepatoblasts keep adherence junction between them during moving in transverse septum.
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