| Budget Amount *help |
¥3,950,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2007: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2006: ¥2,000,000 (Direct Cost: ¥2,000,000)
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| Research Abstract |
Twenty four cases of sudden infant death under lyear old were examined systematically. Five of 24 cases showed macroscopic cardiac abnormality, which were total anomalous pulmonary venous connection (1 cases), aneurysm of sinus valsalva (2 cases), and coactation of aorta (2 cases). In a case of aneurysm of sinus valsalva showed also atrial septal defect and patatent ductus arteriosus. In microscopically, two cases showed hypertrophic cardiomyopathy, and focal myocardial infarction, respectively, and a case of rheumatic myocarditis, cytomegello myocarditis, was found respectively. In cardiac conduction system, 12 cases showed anomalous accessory connection,. Eleven of 24 cases showed aplasty or hypoplasty of medullary arcuate nucleus, and 8 of 12 cases had anomalous accessory connection in conduction system. And also, 7 cases showed all 3 factors which are brain stem abnormality, prone positioned sleeping, cardiac abnormality, and 6 cases showed 2 kind of abnormal findings. Our results showed overlapping of abnormalities of sleeping position with silent cardiac and brain stem abnormalities have the additional risk of sudden infant death.
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