Development of sensitive detection method for chelated poisons using elecrospray ionization mass spectrometry

• Project/Area Number: 18590631
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Legal medicine
• Research Institution: Hamamatsu University School of Medicine
• Principal Investigator: MINAKATA Kayoko Hamamatsu University School of Medicine, 医学部, 講師 (70115509)
• Project Period (FY): 2006 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,140,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥540,000); Fiscal Year 2009: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000); Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2007: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2006: ¥1,800,000 (Direct Cost: ¥1,800,000)
• Keywords: 薬毒物 / 錯体 / 質量分析 / イオンスプレー / 亜ヒ酸 / ヒ酸 / モノメチルアルソン酸 / ジメチルアルシン酸 / シアナイド / サルファイド / ピロリジンジチオカルバミン / クエン酸 / Urine Luck / クロム / シスプラチン / プラチナ / コバルト / ドーピング / エレクトロスプレー / 銀 / ジエチルジチオカルバミン / モリブデン / ルテニウム

Research Abstract

イオンスプレー質量分析法(ESI-MS)は分子構造の解明に最適な方法であるが、分子が強く荷電して水溶性が高い場合にはイオン化できず、検出ができないという欠点がある。申請者は検出できていなかった薬毒物を錯体化合物とし、さらに第三の因子を反応させて分子を励起し、これらを極性有機溶媒で抽出することによりイオン化をさらに促進し、ESI-MSで高感度に検出する方法を見出した。この方法により中毒者試料中のモリブデン、6価クロム、シスプラチン、コバルト、ヒ酸、亜ヒ酸、モノメチルヒ素、ジメチルヒ素、シアナイドを同定・定量した。

Research Products

• [Journal Article] Determination of cyanide, in urine and gastric content, by electrospray ionization tandem mass spectrometry after direct flow injection of dicyanogold (2009)
  • Author(s): Kayoko Minakata, Hideki Nozawa, et. al.
  • Journal Title: Analytica Chimica Acta 651 Pages: 81-84
  • NAID: 120005314222
  • Peer Reviewed
• [Journal Article] Electrospray ionization tandem mass spectrometric determination of monomethylarsonic acid and dimethylarsinic acid after adduct formation with citric acid (2009)
  • Author(s): Kayoko Minakata, Kazuo Ohnishi, et. al.
  • Journal Title: Journal of Chromatography B 877 Pages: 2624-2629
  • NAID: 10028022512
  • Peer Reviewed
• [Journal Article] Simple and selective determination of arsenite and arsenate by electrospray ionization mass spectrometry (2009)
  • Author(s): Kayoko Minakata, Masako Suzuki, Osamu Suzuki
  • Journal Title: Analytica Chimica Acta 631 Pages: 87-90
  • NAID: 120005314113
  • Peer Reviewed
• [Journal Article] Itaru Yamagishi, Kunio Gonmori, Kayoko Minakata, Osamu Suzuki, Application of thermoresponsive HPLC to forensic toxicology: determination of barbiturates in human urine (2009)
  • Author(s): Sanae Kanno, Kanako Watanabe, Seishiro Hirano
  • Journal Title: Forensic Toxicology 27 Pages: 103-106
  • Peer Reviewed
• [Journal Article] Sensitive determination of arsenite and arsenate in plasma by electrospray ionization tandem mass spectrometry after chelate formation (2009)
  • Author(s): Kayoko Minakata, Hideki Nozawa, et. al.
  • Journal Title: Forensic Toxicology 27 Pages: 37-40
  • Peer Reviewed
• [Journal Article] Electrospray ionization tandem mass spectrometric determination of monomethyl-arsonic acid and dimethylarsinic acid after adduct formation with citric acid (2009)
  • Author(s): Kayoko Minakata
  • Journal Title: Journal of Chromatography B 877 Pages: 2624-2629
  • NAID: 10028022512
  • Peer Reviewed
• [Journal Article] Determination of cyanide, in urine and gastric content, by electrospray ionization tandem mass spectrometry after direct flow injection of dicyanogold (2009)
  • Author(s): Kayoko Minakata
  • Journal Title: Analytica Chimica Acta 651 Pages: 81-84
  • NAID: 120005314222
  • Peer Reviewed
• [Journal Article] Simple and selective determination of arsenite and arsenate by electrospray ionization mass spectrometry (2009)
  • Author(s): Kayoko Minakata
  • Journal Title: Analytica Chimica Acta 631 Pages: 87-90
  • NAID: 120005314113
  • Peer Reviewed
• [Journal Article] Sensitive determination of arsenite and arsenate in plasma by electrospray ionization tandem mass spectrometry after chelate formation (2009)
  • Author(s): Kayoko Minakata
  • Journal Title: Forensic Toxicology 27 Pages: 37-40
  • Peer Reviewed
• [Journal Article] Determination of Urine Luck in urine using electrospray ionization tandem mass spectrometry (2008)
  • Author(s): Kayoko Minakata, Hideki Nozawa, et. al.
  • Journal Title: Forensic Toxicology 26 Pages: 71-75
  • Peer Reviewed
• [Journal Article] Application of electrospray ionization tandem mass spectrometry for the rapid and sensitive determination of cobalt in urine (2008)
  • Author(s): Kayoko Minakata, Masako Suzuki, Osamu Suzuki
  • Journal Title: Analytica Chimica Acta 614 Pages: 161-164
  • Peer Reviewed
• [Journal Article] Determination of Urine Luck in urine using electrospray ionization tandem mass spectrometry, Proceedings in The International of Forensic Toxicologist (2008)
  • Author(s): Kayoko Minakata, Kunio Gonmori, Osamu Suzuki
  • Journal Title: 45th International Meeting (published in)
  • Peer Reviewed
• [Journal Article] Determination of Urine Luck in urine using electrospray ionization tandem mass spectrometry (2008)
  • Author(s): Kayoko Minakata, Hideki Nozawa, et.al
  • Journal Title: Forensic Toxicology 26 Pages: 71-75
  • Peer Reviewed
• [Journal Article] Application of electrospray ionization tendem mass spectrometry for the rapid and sensitive determination of cobalt in urine (2008)
  • Author(s): Kayoko Minakata
  • Journal Title: Analytica Chimica Acta 614 Pages: 161-164
  • Peer Reviewed
• [Journal Article] Determination of Urine Luck in urine using electrospray ionization tandem mass spectrometry (2008)
  • Author(s): Kayoko Minakata
  • Journal Title: Forensic Toxicology 26 Pages: 71-75
  • Peer Reviewed
• [Journal Article] Platinum levels in various tissues of a patient died 181 days after cisplatin overdose determined by electrospray ionization mass spectrometry, Proceedings in The International of Forensic Toxicologist (2007)
  • Author(s): Kayoko Minakata, Osamu Suzuki
  • Journal Title: 44th International Meeting (published in)
  • Peer Reviewed
• [Journal Article] Studies on the cause of an encephalopathy which took place in the limited areas in Japan 2004: a possibility of poisoning by cyanide being contained in a kind of mushroom, Proceedings in The International of Forensic Toxicologist (2007)
  • Author(s): Kunio Gonmori, Kayoko Minakata, Kanako Watanabe, et. al.
  • Journal Title: 44th International Meeting (published in)
  • Peer Reviewed
• [Journal Article] Trace analysis of platinum in blood and urine by ESI-MS-MS (2007)
  • Author(s): Kayoko Minakata, Hideki Nozawa, et. al.
  • Journal Title: Forensic Toxicology 25 Pages: 84-87
  • Peer Reviewed
• [Journal Article] Trace analysis of platinum in blood and urine by ESI-MS-MS (2007)
  • Author(s): Kayoko Minakata
  • Journal Title: Forensic Toxicology 25 Pages: 84-87
  • Peer Reviewed
• [Journal Article] Platinum levels in various tissues of a patient died 181 days after cispl atinoverdose determined by electrospray ionization mass spectrometry (2007)
  • Author(s): Kayoko Minakata
  • Journal Title: Proceedings of The International Association of Forensic Toxicologists 2006 CT-P-13 Pages: 1-6
  • Peer Reviewed
• [Journal Article] Studies on the cause of anencephlopathy which took place in the limit edaareas in Japan 2004:a possibility of poisoning by cyanide being contained in a kind of mushroom (2007)
  • Author(s): Kunio Gonmori
  • Journal Title: Proceedings of The International Association of Forensic Toxicologists 2006 TH-P-1 Pages: 1-3
  • Peer Reviewed
• [Journal Article] Rapid and sensitive determination of Urine Luck by ESI-MS after reduction of chromate. Proceedings in The International of Forensic Toxicologist (2006)
  • Author(s): Kayoko Minakata, Osamu Suzuki
  • Journal Title: 43rd International Meeting (published in)
  • Peer Reviewed
• [Journal Article] Platinum levels in various tissues of a patient who died 181 days after cisplatin overdosing determined by electrospray ionization mass spectrometry (2006)
  • Author(s): Kayoko Minakata, Masako Suzuki, et. al.
  • Journal Title: Forensic Toxicology 24 Pages: 83-87
  • Peer Reviewed
• [Journal Article] Determination of molybdenum and/or ruthenium in urine using electrospray ionization mass spectrometry (2006)
  • Author(s): Kayoko Minakata, Masako Suzuki, Osamu Suzuki
  • Journal Title: Analytical Biochemistry 348 Pages: 148-150
  • NAID: 120006510544
  • Peer Reviewed
• [Journal Article] Determination of platinum derived from cisplatin in human tissues using electrospray ionization mass spectrometry (2006)
  • Author(s): Kayoko Minakata, Hideki Nozawa, et. al.
  • Journal Title: Journal of Chromatography B 832 Pages: 286-291
  • NAID: 10025780926
  • Peer Reviewed
• [Journal Article] Rapid and sensitive identification and determination of Urine Luck by ESI-MS after reduction of chromate. (2006)
  • Author(s): Kayoko Minakata, Kunio Gonmori, et. al.
  • Journal Title: Forensic Toxicology 24 Pages: 48-50
  • Peer Reviewed
• [Journal Article] Determination of platinum derived from cisplatin in human tissues using electrospray ionization mass spectrometry (2006)
  • Author(s): Kayoko Minakata, Hideki Nozawa, et.al
  • Journal Title: Journal of Chromatography B 832 Pages: 286-291
  • NAID: 10025780926
  • Peer Reviewed
• [Journal Article] Determination of platinum derived from cisplatin in human tissues using electrospray ionization mass spectrometry (2006)
  • Author(s): Kayoko Minakata
  • Journal Title: Journal of Chromatography B 832 Pages: 286-291
  • NAID: 10025780926
• [Journal Article] Determination of molybdenum and/or ruthenium in urine using electrospray ionization mass spectrometry (2006)
  • Author(s): Kayoko Minakata
  • Journal Title: Analytical Biochemistry 348 Pages: 148-150
  • NAID: 120006510544
• [Journal Article] Rapid and sensitive identification and determination of Urine Luck by ESI-MS after reduction of chromate (2006)
  • Author(s): Kayoko Minakata
  • Journal Title: Forensic Toxicology 24 Pages: 48-50
• [Journal Article] Platinum levels in various tissues of a patient who died 181 days after cisplatin overdosing determined by electrospray ionization mass spectrometry (2006)
  • Author(s): Kayoko Minakata
  • Journal Title: Forensic Toxicology 24 Pages: 83-87
• [Presentation] Simple and sensitive determination of arsenite and arsenate by electrospray ionization mass spectrometry (2009)
  • Author(s): Kayoko Minakata, Kunio Gonmori, Osamu Suzuki
  • Organizer: 47th Meeting of The International Association of Forensic Toxicologists
  • Place of Presentation: Geneva, Switzerland
• [Presentation] 尿中ヨウ化物イオン、ヨウ素酸イオンのESI-MS-MSによる定量 (2009)
  • Author(s): 南方かよ子、鈴木雅子, 他8名
  • Organizer: 第34回日本医用マススペクトル学会年会
  • Place of Presentation: 大阪
• [Presentation] 血漿中無機ヒ素類錯体化合物のESI-MS-MSによる高感度迅速定量法 (2009)
  • Author(s): 南方かよ子、権守邦夫, 他6名
  • Organizer: 日本法中毒学会第28年会
  • Place of Presentation: 金沢
• [Presentation] タンデム質量分析法を用いたコバルトの高感度定量 (2009)
  • Author(s): 南方かよ子、野澤秀樹, 他5名
  • Organizer: 第93次日本法医学会学術集会
  • Place of Presentation: 大阪
• [Presentation] パラコート及びジクワットの細胞内毒性に関する研究:その1 (2009)
  • Author(s): 菅野さな枝、権守邦夫、鈴木雅子、南方かよ子, 他3名
  • Organizer: 日本薬学会第129年会
  • Place of Presentation: 京都
• [Presentation] タンデム質量分析法を用いた尿中コバルトの高感度定量 (2009)
  • Author(s): 南方かよ子
  • Organizer: 日本法医学会
  • Place of Presentation: 大阪
• [Presentation] 血漿中無機ヒ素錯体化合物のESI-MS-MSによる高感度迅・速定量法 (2009)
  • Author(s): 南方かよ子
  • Organizer: 日本法中毒学会
  • Place of Presentation: 金沢
• [Presentation] Simple and sensitive determination of arsenite and arsenate by electrospray ionization mass spectrometry (2009)
  • Author(s): 南方かよ子
  • Organizer: The International Association of Forensic Toxicologists
  • Place of Presentation: Geneva, Switzerland
• [Presentation] 尿中ヨウ化物イオン、ヨウ素酸イオンのESI-MS-MSによる定量 (2009)
  • Author(s): 南方かよ子
  • Organizer: 日本医用マススペクトル学会
  • Place of Presentation: 大阪
• [Presentation] Determination of cobalt in urine to discriminate its excessive administration using electrospray ionization tandem mass spectrometry (2008)
  • Author(s): Kayoko Minakata, Kunio Gonmori, Osamu Suzuki
  • Organizer: The International Association of Forensic Toxicologists
  • Place of Presentation: La Martinique, France
  • Year and Date: 2008-06-07
• [Presentation] Solvent extraction procedure for the differential determination of arsenite and arsenate by electrospray ionization mass spectrometry (2008)
  • Author(s): Kayoko Minakata, Hideki Nozawa, et. al.
  • Organizer: International Symposium, Advances in Legal Medicine
  • Place of Presentation: Osaka, Japan
• [Presentation] Determination of cobalt in urine to discriminate its excessive administration using electrospray ionization tandem mass spectrometry (2008)
  • Author(s): Kayoko Minakata, Kunio Gonmori, Osamu Suzuki
  • Organizer: 46th Meeting of The International Association of Forensic Toxicologists
  • Place of Presentation: La Martinique, France
• [Presentation] Kayoko Minakata, et al., Analysis of drugs and poisons by LC-TOF-MS: preliminary studies on mushroom toxin alpha-amanitin (2008)
  • Author(s): Kunio Gonmori, Masako Suzuki, Atuko Hunakoshi
  • Organizer: 46th Meeting of The International Association of Forensic Toxicologists
  • Place of Presentation: La Martinique, France
• [Presentation] クエン酸を付加させたモノメチルアルソン酸、ジメチルアルシン酸のESI-MS-MSによる定量 (2008)
  • Author(s): 南方かよ子、鈴木雅子、鈴木修
  • Organizer: 第33回日本医用マススペクトル学会年会
  • Place of Presentation: 東京
• [Presentation] 亜ヒ酸、ヒ酸のESI-MSを用いた高感度迅速定量法 (2008)
  • Author(s): 南方かよ子、権守邦夫, 他6名
  • Organizer: 日本法中毒学会第27年会
  • Place of Presentation: 東京
• [Presentation] イオンクロマトグラフィによるきのこ含有青酸測定法の検討 (2008)
  • Author(s): 権守邦夫、船越敦子、南方かよ子, 他6名
  • Organizer: 日本法中毒学会第27年会
  • Place of Presentation: 東京
• [Presentation] タンデム質量分析法を用いた血液と尿中のプラチナの高感度定量 (2008)
  • Author(s): 南方かよ子、野澤秀樹, 他4名
  • Organizer: 第92次日本法医学会総会
  • Place of Presentation: 長崎
• [Presentation] Solvent extraction procedure for the differential determination of arsenite and arsenate by electrospray ionization mass spectrometry (2008)
  • Author(s): Kayoko Minakata, Hideki Nozawa, et.al
  • Organizer: International Symposium, Advances in Legal Medicine, September
  • Place of Presentation: Osaka, Japan
• [Presentation] タンデム質量分析法を用いた血液と尿中のプラチナの高感度定量 (2008)
  • Author(s): 南方かよ子
  • Organizer: 日本法医学会
  • Place of Presentation: 長崎
• [Presentation] ラマン分光による亜ヒ酸とシアン化合物の直接検出 (2008)
  • Author(s): 権守邦夫
  • Organizer: 日本法医学会
  • Place of Presentation: 長崎
• [Presentation] Determination of cobalt in urine to discriminate its excessive administration using eleetrospray ionization tandem mass spectrometry (2008)
  • Author(s): Kayoko Minakata
  • Organizer: The International Association of Forensic Toxicologists
  • Place of Presentation: La Martinique, France
• [Presentation] Analysis of drugs and poisons by LC-TOF-MS : preliminary studies on mushroom toxin alpha-amanitin (2008)
  • Author(s): Kunio Gonmori
  • Organizer: The International Association of Forensic Toxicologists
  • Place of Presentation: La Martinique, France
• [Presentation] 亜ヒ酸、ヒ酸のESI-MSを用いた高感度迅速定量法 (2008)
  • Author(s): 南方かよ子
  • Organizer: 日本法中毒学会
  • Place of Presentation: 東京
• [Presentation] イオンクロマトグラフィによるきのこの含有青酸測定法の検討 (2008)
  • Author(s): 権守邦夫
  • Organizer: 日本法中毒学会
  • Place of Presentation: 東京
• [Presentation] Solvent extraction procedures for the differential determination of arsenite and arsenate by electrospray ionization mass spectrometry (2008)
  • Author(s): Kayoko Minakata
  • Organizer: International Symposium, Advances in Legal Medicine
  • Place of Presentation: 大阪
• [Presentation] クエン酸を付加させたモノメチルアルソン酸、ジメチルアルシン酸のESI-MS-MSによる定量 (2008)
  • Author(s): 南方かよ子
  • Organizer: 日本医用マススペクトル学会
  • Place of Presentation: 東京
• [Presentation] トライエージDOA検査の尿以外試料への適用性 (2007)
  • Author(s): 鈴木修、野澤秀樹、権守邦夫、渡部加奈子、南方かよ子
  • Organizer: 第29回法医学会中部地方会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-10-27
• [Presentation] トライエージDOA検査の尿以外試料への適用性 (2007)
  • Author(s): 鈴木 修
  • Organizer: 日本法医学会中部地方会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-10-27
• [Presentation] Determination of Urine Luck in urine using electrospray ionization tandem mass spectrometry (2007)
  • Author(s): Kayoko Minakata, Kunio Gonmori, Osamu Suzuki
  • Organizer: The International Association of Forensic Toxicologists
  • Place of Presentation: Seattle, USA
  • Year and Date: 2007-08-28
• [Presentation] Determination of Urine Luck in urine using electrospray ionization tandem mass spectrometry (2007)
  • Author(s): Kayoko Minakata, Kunio Gonmori, Osamu Suzuki
  • Organizer: 45th Meeting of The International Association of Forensic Toxicologists
  • Place of Presentation: Seattle, USA
• [Presentation] Analysis of drugs and poisons by LC-TOF-MS: Preliminary studies on magic mushroom toxins psilocin and psilocybin (2007)
  • Author(s): Kunio Gonmori, Masako Suzuki, Kayoko Minakata, et. al.
  • Organizer: 45th Meeting of The International Association of Forensic Toxicologists
  • Place of Presentation: Seattle, USA
• [Presentation] 金属錯体のエレクトロスプレーイオン化MS/MSによる分析 (2007)
  • Author(s): 南方かよ子、鈴木修
  • Organizer: 第32回日本医用マススペクトル学会年会
  • Place of Presentation: 京都
• [Presentation] ESI-MS/MSを用いた6価クロムの高感度迅速定量法 (2007)
  • Author(s): 南方かよ子、権守邦夫, 他4名
  • Organizer: 日本法中毒学会第26年会
  • Place of Presentation: 延岡
• [Presentation] シスプラチンの過剰投与後181日で死亡した患者の組織、血液、尿中のプラチナの定量 (2007)
  • Author(s): 南方かよ子、野澤秀樹, 他3名
  • Organizer: 第91次日本法医学会総会
  • Place of Presentation: 秋田
• [Presentation] スギヒラタケ含有青酸濃度について (2007)
  • Author(s): 権守邦夫、松本則行、野澤秀樹、南方かよ子, 他2名
  • Organizer: 第91次日本法医学会総会
  • Place of Presentation: 秋田
• [Presentation] シスプラチン過剰投与後181日で死亡した患者の組織、血液、尿中のプラチナの定量 (2007)
  • Author(s): 南方 かよ子
  • Organizer: 日本法医学会総会
  • Place of Presentation: 秋田
• [Presentation] スギヒラタケ含有青酸濃度について (2007)
  • Author(s): 権守 邦夫
  • Organizer: 日本法医学会総会
  • Place of Presentation: 秋田
• [Presentation] Determination of Urine Luck in urine using electrospray ionization tandem mass spectrometry (2007)
  • Author(s): Kayoko Minakata
  • Organizer: The International Association of Forensic Toxicologists 2007
  • Place of Presentation: Seattle,USA
• [Presentation] Analysis of drugs and poisons by LC-TOF-MS:Preliminary studies on Inagic mushroom toxins psilocin and psilocybin (2007)
  • Author(s): Kunio Gonmori
  • Organizer: The International Association of Forensic Toxicologists 2007
  • Place of Presentation: Seattle,USA
• [Presentation] 金属錯体のエレクトロスプレーイオン化MSIMSによる分析 (2007)
  • Author(s): 南方 かよ子
  • Organizer: 日本医用マススペクトル学会年会
  • Place of Presentation: 京都
• [Presentation] Studies on the cause of an encephalopathy which took place in the limited areas in Japan 2004 : a possibility of poisoning by cyanide being contained in a kind of mushroom (2006)
  • Author(s): Kunio Gonmori, Kayoko Minakata, Kanako Watanabe, et.al
  • Organizer: The International Association of Forensic Toxicologists
  • Place of Presentation: Ljubljana, Slovenia
  • Year and Date: 2006-08-29
• [Presentation] Platinum levels in various tissues of a patient died 181 days after cisplatin overdose determined by electrospray ionization mass spectrometry (2006)
  • Author(s): Kayoko Minakata, Osamu Suzuki
  • Organizer: The International Association of Forensic Toxicologists
  • Place of Presentation: Ljubljana, Slovenia
  • Year and Date: 2006-08-28
• [Presentation] Platinum levels in various tissues of a patient died 181 days after cisplatin overdose determined by electrospray ionization mass spectrometry (2006)
  • Author(s): Kayoko Minakata, Osamu Suzuki
  • Organizer: 44th Meeting of The International Association of Forensic Toxicologists
  • Place of Presentation: Ljubljana, Slovenia
• [Presentation] Studies on the cause of an encephalopathy which took place in the limited areas in Japan 2004: a possibility of poisoning by cyanide being contained in a kind of mushroom (2006)
  • Author(s): Kunio Gonmori, Kayoko Minakata, Kanako Watanabe, et. al.
  • Organizer: 44th Meeting of The International Association of Forensic Toxicologists
  • Place of Presentation: Ljubljana, Slovenia
• [Presentation] エレクトロスプレーイオン化質量分析法を用いたシスプラチン過剰投与患者組織中のプラチナの定量 (2006)
  • Author(s): 南方かよ子、野澤秀樹, 他4名
  • Organizer: 日本法中毒学会第25年会
  • Place of Presentation: 東京
• [Presentation] スギヒラタケおよび近縁きのこの法中毒学的検討(第2報) (2006)
  • Author(s): 権守邦夫、岡本直子、南方かよ子, 他10名
  • Organizer: 日本法中毒学会第25年会
  • Place of Presentation: 東京
• [Presentation] エレクトロスプレーイオン化質量分析法を用いた銀の高感度迅速定量法 (2006)
  • Author(s): 南方かよ子、権守邦夫, 他3名
  • Organizer: 第90次日本法医学会
  • Place of Presentation: 福岡
• [Presentation] 日本人喫煙者における一酸化炭素ヘモグロビン濃度について (2006)
  • Author(s): 権守邦夫、野澤秀樹、南方かよ子, 他2名
  • Organizer: 第90次日本法医学会
  • Place of Presentation: 福岡
• [Book] 生命倫理事典 (2010)
  • Author(s): 酒井明夫, 他
  • Total Pages: 2
  • Publisher: 太陽出版
• [Book] 生命倫理事典 (2010)
  • Author(s): 酒井明夫
  • Total Pages: 2
  • Publisher: 太陽出版
• [Book] 薬毒物分析辞典 (2009)
  • Author(s): 高取健彦, 他
  • Total Pages: 9
  • Publisher: 廣川書店
• [Book] 薬毒物分析学辞典 (2009)
  • Author(s): 高取健彦
  • Total Pages: 9
  • Publisher: 廣川書店
• [Remarks] 発表した16件の雑誌論文のうち、4件のProceedingsを除いた12件は浜松医科大学学術機関リポジトリにて公開されている。
  • URL: http://hikumano.hama-med.ac.jp/dspace/