The Role of Side Population Cell in Skeletal Muscle on post infarcted LV remodeling

• Project/Area Number: 18590785
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Circulatory organs internal medicine
• Research Institution: Osaka City University
• Principal Investigator: YOSHIYAMA Minoru Osaka City University, Department of Internal Medicine and Cardiology, Professor (30240956)
• Project Period (FY): 2006 – 2007
• Project Status: Completed (Fiscal Year 2007)
• Budget Amount: ¥3,890,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥390,000); Fiscal Year 2007: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2006: ¥2,200,000 (Direct Cost: ¥2,200,000)
• Keywords: Side Population Cell / Transplantation / Regenerative Medicin

Research Abstract

Despite the advance in pharmacotherapeutics and mechanical interventions, the cardiomyocytes lost during myocardial infarction (MI) cannot be regenerated. Consequently, the loss of cardiomyocytes in MI is a major cause of heart failure. As a potential method, cell transplantation to myocardium has been studied for a decade. Side Population Cell in Skeletal Muscle transplantation could be potential therapy for heart damage in experimentally. However, the safety, efficacy of their transplantation are controversial. In this study, we investigate that whether Side Population' Cell in Skeletal Muscle can be a good cell source. In the present study, we transplanted Side Population Cell in Skeletal Muscle into infracted mouse hearts and investigate that (1) whether engrafted Side Population Cell in Skeletal Muscle improve post infarcted cardiac function, (2) whether Side Population Cell in Skeletal Muscle myoblasts can transdifferentiate into cardiomyocytes in vitro and in vivo.

Research Products

• [Journal Article] Comparison of clinical characteristics and arterial remodeling by intrava scular ultrasonic imaging in three age groups(<or=55,56 to 69 and>or=70years)of Japanese patients with acute myocardial infarction (2007)
  • Author(s): Ehara S, Naruko T, Kobayashi Y, Kataoka T, Nakagawa M, Shirai N, Ishii H, Okuyama T, Oe H, Sugioka K, Hozumi T, Haze K, Yoshikawa J, Yoshiyama M, Ueda M
  • Journal Title: Am J Cardiol 100(12) Pages: 1713-1717
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Measuring visceral fat with water-selective suppression methods(SPIR,SPAIR)in patients with metabolic syndrome (2007)
  • Author(s): Tanaka S, Yoshiyama M, Imamshi Y, Teragaki M, Kasayuki N, Shimizu N, Nakahira K, Hanaki T, Naito Y, Tanaka M, Inoue Y
  • Journal Title: Magn Reson Med Sci 6(3) Pages: 171-175
  • NAID: 10019798255
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] The simultaneous assessment of aortic valve area and coronary artery stenosis using 16-slice multidetector-row computed tomography in patients with aortic stenosis comparison with echocardiography (2007)
  • Author(s): Tanaka H, Shimada K, Yoshida K, Jissho S, Yoshikawa J, Yoshiyama M
  • Journal Title: Circ J 71(10) Pages: 1593-1598
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Impact of statin therapy on systemic inflammation,left ventricular syst olic and diastolic function and prognosis in low risk is chemic heart disease patients without history of congestive heart failure (2007)
  • Author(s): Okura H, Asawa K, Kubo T, Taguchi H, Toda I, Yoshiyama M, Yoshikawa J, Yoshida K
  • Journal Title: Intern Med 46(17) Pages: 1337-1343
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Functional Mitral Regurgitation Predicts Prognosis Independent of Left Ventricular Systolic and Diastolic Indices in Patients with Ischemic Heart Disease (2007)
  • Author(s): Okura H, Takada Y, Kubo T, Asawa K, Taguchi H, Toda I, Yoshiyama M, Yoshikawa J, Yoshida K
  • Journal Title: J Am Soc Echocardiogr 21(4) Pages: 355-360
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Hypertrophic cardiomyopathy is associated with more severe left ventricular dyssynchrony than is hypertensive left ventricular hypertrophy (2007)
  • Author(s): Nagakura T, Takeuchi M, Yoshitani H, Nakai H, Nishikage T, Kokumai M, Otani S, Yoshiyama M, Yoshikawa J
  • Journal Title: Echocardiography 24(7) Pages: 677-684
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Comparative study ofh igh-resolution microimaging with 30-MHz scanner for evaluating cardiac function in mice (2007)
  • Author(s): Okajima K, Abe Y, Fujimoto K, Fujikura K, Girard EE, Asai T, Kwon SH, Jin Z, Nakamura Y, Yoshiyama M, Homma S
  • Journal Title: J Am Soc Echocardiogr 20(10) Pages: 1203-1210
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Effects of gender on prognosis of patients with known or suspected cornnary artery disease undergoing contrast-enhanced dobutamine stress echocardiography (2007)
  • Author(s): Wake R, Takeuchi M, Yoshikawa J, Yoshiyama M
  • Journal Title: Circ J. 71(7) Pages: 1060-1066
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Neopterin is associated with plaque inflammation and destabilisation in human coronary atherosclerotic lesions (2007)
  • Author(s): Adachi T, Naruko T, Itoh A, Komatsu R, Abe Y, Shirai N, Yamashita H, Ehara S, Nakagawa M, Kitabayashi C, Ikura Y, Ohsawa M, Yoshiyama M, Haze K, Ueda M
  • Journal Title: Heart 93(12) Pages: 1537-1541
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Relation of early improvement in coronary flow reserve to late recovery of left ventricular function after beba-blocker therapy in patients with idiopathic dilated cardiomyopathy (2007)
  • Author(s): Sugioka K, Hozumi T, Takemoto Y, Ehara S, Ogawa K, Iwata S, Oe H, Matsumura Y, Otsuka R, Yoshiyama M, Yoshikawa J
  • Journal Title: Am Heart J. 153(6)
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Approach to the asymptomatic patients with Brugada syndrome (2007)
  • Author(s): Takagi M, Tatsumi H, Yoshiyama M
  • Journal Title: Indian Pacing Electrophysiol J 7(2) Pages: 73-76
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Altered coronary vasomotor function in young patients with systemic lupus erythematosus (2007)
  • Author(s): Hirata K, Kadirvelu A, Kinjo M, Sciacca R, Sugioka K, Otsuka R, Choy A, Chow SK, Yoshiyama M, Yoshikawa J, Homma S, Lang CC
  • Journal Title: Arthritis Rheum 56(6) Pages: 1904-1909
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] QT dispersion and prognosis after coronary stent placement in acute myocardial infarction (2007)
  • Author(s): Ueda H, Hayashi T, Tsumufa K, Kaitani K, Yoshimaru K, Nakayama Y, Yoshiyama M
  • Journal Title: Clin Cardiol 30(5) Pages: 229-233
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Elevated plasma levels of oxidized low-density lipoprotein relate to the presenceof angiographically detected complex and thrombotic coronary artery lesion morphology in patients with unstable angina (2007)
  • Author(s): Yamashita H, Ehara S, Yoshiyama M, Naruko T, Haze K, Shirai N, Sugama Y, Ikura Y, Ohsawa M, Itabe H, Kataoka T, Kobayashi Y, Becker AE, Yoshikawa J, Ueda M
  • Journal Title: Circ J 71(5) Pages: 681-687
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Atherosclerotic plaque with ultrasonic attenuation affects coronary reflow and infarct size in patients with acute coronary syndrome:an intravascular ultrasound study (2007)
  • Author(s): Okura H, Taguchi H, Kubo T, Toda I, Yoshida K, Yoshiyama M, Yoshikawa J
  • Journal Title: Circ J 71(5) Pages: 648-653
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] The long-acting Ca^<2+>-channel blocker azelnidipine prevents left ventricular remodeling after myocardial infarction (2007)
  • Author(s): Nishiya D, Enomoto S, Omura T, Matsumoto R, Kusuyama T, Izumi Y, Iwao H, Takeuchi K, Yoshiyama M
  • Journal Title: J Pharmacol Sci 103(4) Pages: 391-397
  • NAID: 10024313539
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Impact of arterial remodelling and plaque rupture on target and non-target lesion revascularisation after stent implantation in patients with acute coronary syndrome:an intravascular ultrasound study (2007)
  • Author(s): Okura H, Taguchi H, Kubo T, Toda I, Yoshiyama M, Yoshikawa J, Yoshida K
  • Journal Title: Heart 93(10) Pages: 1219-1225
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Quantification of coronary calcification by intravascular ultrasound (2007)
  • Author(s): Ehara S, Kobayashi Y, Kataoka T, Yoshiyama M, Ueda M, Yoshikawa J
  • Journal Title: Circ J 71(4) Pages: 530-535
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Beta-blocker therapy induces ventricular resynchronization in dilated cardiomyopathy with narrow QRS complex (2007)
  • Author(s): Takemoto Y, Hozumi T, Sugioka K, Takagi Y, Matsumura Y, Yoshiyama M, Abraham TP, Yoshikawa J
  • Journal Title: J Am Coll Cardiol 49(7) Pages: 778-783
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] The effect of the gravitation of the moon on acute myocardial infarction (2007)
  • Author(s): Wake R, Fukuda D, Yoshiyama M, Shimada K, Yoshikawa J
  • Journal Title: Am J Emerg Med 25(2) Pages: 256-258
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Xenotransplantation of Iong-term-cultured swine bone marrow-derived mesenchymal stem cells (2007)
  • Author(s): Nakamura Y, Wang X, Xu C, Asakura A, Yoshiyama M, From AH, Zhang J
  • Journal Title: Stem Cells 25(3) Pages: 612-620
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Xenotransplantation of long-term-cultured swine bone marrow-derived mesenchymal stem cells (2007)
  • Author(s): Nakamura, Y. Wang, X., Xu, C., Asakura, A., Yoshiyama, M., AH, Zhang, J
  • Journal Title: 25(3) Pages: 612-620
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Comparion of clinical characateristics and arterial remodeling by intravascular ultrasonic imaging in three age groups (<or=55,56 to 69 and >or =70 years) of Japanese patients with acute myocardial infarction. (2007)
  • Author(s): Ehara S, Naruko T, Kobayashi Y, Kataoka T, Nakagawa M, Shirai N, Ishii H, Okuyama T, Oe H, Sugioka K, Hozumi T, Haze K, Yoshikawa J, Yoshiyama M, Ueda M.
  • Journal Title: Am J Cardiol. 100(12) Pages: 1713-1717
  • Peer Reviewed
• [Journal Article] Measuring visceral fat with water-selective suppression methods (SPIR,SPAIR)in patients with metabolic syndrome. (2007)
  • Author(s): Tanaka S, Yoshiyama M, Imanishi Y, Teragaki M, Kasayuki N, Shimizu N, Nakahira K, Hanaki T, Naito Y, Tanaka M, Inoue Y.
  • Journal Title: Magn Reson Med Sci. 6(3) Pages: 171-175
  • NAID: 10019798255
  • Peer Reviewed
• [Journal Article] The simultaneous assessment of aortic valve area and coronary artery stenosis using 16-slice multidetector-row computed tomography i patients with aortic stenosis comparion with echcardiography. (2007)
  • Author(s): Tanaka H, Shimada K, Yoshida K, Jissho S, Yoshikawa J, Yoshiyama M.
  • Journal Title: Circ J. 71(10) Pages: 1593-1598
  • Peer Reviewed
• [Journal Article] Impact of therapy on systemic inflammation, left ventricular systolic and diastolic function and prognosis in low risk ischemic heart disease patients without history of congestive hear failure. (2007)
  • Author(s): Okura H, Asawa K, Kubo T, Taguchi H, Toda I, Yoshiyama M, Yoshikawa J, Yoshida K.
  • Journal Title: Intern Med. 46(17) Pages: 1337-1343
  • Peer Reviewed
• [Journal Article] Functional Mitral Regurgitation Predicts Prognosis Independent of Left Ventricular Systolic and Diastolic Indices in Patients with Iscmic Heart Disease. (2007)
  • Author(s): Okura H, Takada Y, Kubo T, Asawa K, Taguchi H, Toda I, Yoshiyama M, Yoshikawa J, Yoshida K.
  • Journal Title: J Am Soc Echocardiogr. 21(4) Pages: 355-360
  • Peer Reviewed
• [Journal Article] Hypertrophic cardiomyopathy is associated with more severe left ventriculai dyssynchrony than is hypertensive left ventricular hypertrophy. (2007)
  • Author(s): Nagakura T, Takeuchi M, Yoshitani H, Nakai H, Nishikage T, Kokumai M, Otani S, Yoshiyama M, Yoshikawa J.
  • Journal Title: Echocardiography. 24(7) Pages: 677-684
  • Peer Reviewed
• [Journal Article] Conmparative study of high resolution micromaging with 30-MHz scanner for evaluating cardiac function in meice. (2007)
  • Author(s): Okajima K, Abe Y, Fujimoto K, Fujikura K, Girard EE, Asai T, Kwon SH, Jin Z, Nakamura Y, Yoshiyama M, Homma S.
  • Journal Title: J Am Soc Echocaidiogr. 20(10) Pages: 1203-1210
  • Peer Reviewed
• [Journal Article] Effects of gender on prognosis of patients with known or suspected coronary artery disease undergoing contrast-enhanced dobutamine stress echocardiography. (2007)
  • Author(s): Wake R, Takeuchi M, Yoshikawa J, Yoshiyama M.
  • Journal Title: Circ J. 71(7) Pages: 1060-1066
  • NAID: 110006318405
  • Peer Reviewed
• [Journal Article] Neopterin is associated with plaque inflammation and destabilisation in human coronary atherosclerotic lesions. (2007)
  • Author(s): Adachi T, Naruko T, Itoh A, Komatsu R, Abe Y, Shirai N, Yamashita H, Ehara S, Nakagawa M, Kitabayashi C, Ikura Y, Ohsawa M, Yoshiyama M, Haze K, Ueda M.
  • Journal Title: Heart. 93(12) Pages: 1537-1541
  • Peer Reviewed
• [Journal Article] Relation of early improvement in coronary flow reserve to late recovely of left ventricular function after beta-blocker therapy in patients with idiopathic dilated cardiomyopathy. (2007)
  • Author(s): Sugioka K, Hozumi T, Takemoto Y, Ehara S, Ogawa K, Iwata S, Oe H, Matsumura Y, Otsuka R, Yoshiyama M. Yoshikawa J.
  • Journal Title: Am Heart J. 153(6)
  • Peer Reviewed
• [Journal Article] Approach to the asymptomatic patients with Brugada syndrome. (2007)
  • Author(s): Takagi M, Tatsumi H, Yoshiyama M.
  • Journal Title: Indian Pacing Electrophysiol J. 7(2) Pages: 73-76
  • Peer Reviewed
• [Journal Article] Altered coronary vasomotor function in young patients with systemic lupus eryth ematosus. (2007)
  • Author(s): Hirata K, Kadirvelu A, Kinjo M, Sciacca R, Sugioka K, Otsuka R, Choy A, Chow SK, Yoshiyama M, Yoshikawa J, Homma S, Lang CC.
  • Journal Title: Arthritis Rheum. 56(6) Pages: 1904-1909
  • Peer Reviewed
• [Journal Article] QT dispersion and prognosis after coronary stent placement in acute myocardial infarction. (2007)
  • Author(s): Ueda H, Hayashi T, Tsumura K, Kaitani K, Yoshimaru K, Nakayama Y, Yoshiyama M.
  • Journal Title: Clin Cardiol. 30(5) Pages: 229-233
  • Peer Reviewed
• [Journal Article] Elevated plasma levels of oxidized low-density lipoprotein relate to the presenceof angiographically detected complex and thrombotic coronary artery lesion morphology in patients with unstable angina. (2007)
  • Author(s): Yamashita H, Ehara S, Yoshiyama M, Naruko T, Haze K, Shirai N, Sugama Y, Ikura Y, Ohsawa M, Itabe H, Kataoka T, Kobayashi Y, Becker AE, Yoshikawa J, Ueda M.
  • Journal Title: Circ J. 71(5) Pages: 681-687
  • Peer Reviewed
• [Journal Article] Atherosclerotic plaque with ultrasonic attenuation affects coronary reflow and infarct size in patients with acute coronary syndrome:an intravascular ultrasound study. (2007)
  • Author(s): Okura H, Taguchi H, Kubo T, Toda I, Yoshida K, Yoshiyama M, Yoshikawa J.
  • Journal Title: Circ J. 71(5) Pages: 648-653
  • Peer Reviewed
• [Journal Article] The long-acting Ca2+-channel blocker azelnidipine prevents left ventricular remodeling after myocardial infarction. (2007)
  • Author(s): Nishiya D, Enomoto S, Omura T, Matsumoto R, Kusuyama T, Izumi Y, Iwao H, Takeuchi K, Yoshiyama M.
  • Journal Title: J Pharmacol Sci. 103(4) Pages: 391-397
  • NAID: 10024313539
  • Peer Reviewed
• [Journal Article] Impact of arterial remodelling and plaque rupture on target and non-target lesion revascularisation after stent implantation in patients with acute coronary syndrome:an intravascular ultrasound study. (2007)
  • Author(s): Okura H, Taguchi H, Kubo T, Toda I, Yoshiyama M, Yoshikawa J, Yoshida K.
  • Journal Title: Heart. 93(10) Pages: 1219-1225
  • Peer Reviewed
• [Journal Article] Quantification of coronary calcification by intravascular ultrasound. (2007)
  • Author(s): Ehara S, Kobayashi Y, Kataoka T, Yoshiyama M, Ueda M, Yoshikawa J.
  • Journal Title: Circ J. 71(4) Pages: 530-535
  • Peer Reviewed
• [Journal Article] Beta-blocker therapy induces ventricular resynchronization in dilated cardiomyopathy with narrow QRS complex. (2007)
  • Author(s): Takemoto Y, Hozumi T, Sugioka K, Takagi Y, Matsumura Y, Yoshiyama M, Abraham TP, Yoshikawa J.
  • Journal Title: J Am Coll Cardiol. 49(7) Pages: 778-783
  • Peer Reviewed
• [Journal Article] The effect of the gravitation of the moon on acute myocardial infarction. (2007)
  • Author(s): Wake R, Fukuda D, Yoshiyama M, Shimada K, Yoshikawa J.
  • Journal Title: Am J Emerg Med. 25(2) Pages: 256-258
  • Peer Reviewed
• [Journal Article] Xenotransplantation of long-term-cultured swine bone marrow-derived mesenchymal stem cells. (2007)
  • Author(s): Nakamura Y,Wang X,Xu C,Asakura A,Yoshiyama M,From AH, Zhang J.
  • Journal Title: Stem Cells. 25(3) Pages: 612-620
  • Peer Reviewed
• [Journal Article] Usefuines of automated quantitation of regional left ventricular wall motionby a novel method of two-dimensional echocardiographic tracking (2006)
  • Author(s): Ogawa K, Hozumi T, Sugioka K, Matsumura Y, Nishiura M, Kanda R, Abe Y, Takemoto Y, Yoshiyama M, Yoshikawa J.
  • Journal Title: Am J Cardiol 98(11) Pages: 1531-1537
• [Journal Article] Effects of treatment for diabetes mellitus on circulating vascular progenitorcells (2006)
  • Author(s): Kusuyama T, Omura T, Nishiya D, Enomoto S, Matsumoto R, Takeuchi K, Yoshikawa J, Yoshiyama M.
  • Journal Title: J Pharmacol Sci 102(1) Pages: 96-102
• [Journal Article] Automated three-dimensional analysis of mitral annular dynamics in patientswith myocardial infarction using automated mitral annular tracking method (2006)
  • Author(s): Takemoto Y, Hozumi T, Sugioka K, Watanabe H, Matsumura Y, Yoshiyama M, Takeuchi K, Yoshikawa J.
  • Journal Title: Echocardiography 23(8) Pages: 658-665
• [Journal Article] Role of contrast-enhanced dobutamine stress echocardiography in predictingoutcome in patients with known or suspected coronary artery disease (2006)
  • Author(s): Wake R, Takeuchi M, Yoshitani H, Miyazaki C, Otani S, Yoshiyama M, Yoshikawa J.
  • Journal Title: Echocardiography 23(8) Pages: 642-649
• [Journal Article] The effects of HMG-CoA reductase inhibitor on vascular progenitor cells (2006)
  • Author(s): Kusuyama T, Omura T, Nishiya D, Enomoto S, Matsumoto R, Murata T, Takeuchi K, Yoshikawa J, Yoshiyama M.
  • Journal Title: J Pharmacol Sci 101(4) Pages: 344-349
  • NAID: 10018236655
• [Journal Article] Cut-off value of coronary flow velocity reserve by transthoracic Dopplerechocardiography for the assessment of significant donor left anteriordescending artery stenosis in patients with spontaneously visible collaterals (2006)
  • Author(s): Iwata S, Hozumi T, Matsumura Y, Sugioka K, Yoshitani H, Murata E, Takemoto Y, Kobayashi Y, Yoshiyama M, Yoshikawa J.
  • Journal Title: Am J Cardiol 98(3) Pages: 298-302
• [Journal Article] Risk stratification in patients with Brugada syndrome : analysis of dailyfluctuations in 12-lead electrocardiogram (ECG) and signal-averagedelectrocardiogram (SAECG) (2006)
  • Author(s): Tatsumi H, Takagi M, Nakagawa E, Yamashita H, Yoshiyama M.
  • Journal Title: J Cardiovasc Electrophysiol 17(7) Pages: 705-711
• [Presentation] 左冠動脈主幹部プラーク及び頸動脈プラークによる冠動脈病変枝数の予測 (2007)
  • Author(s): 竹下 宏明, 片岡 亨, 穂積 健之, 岩田 真一, 石井 英, 松本 亮, 白井 伸幸, 西岡 弘樹, 嶋田 芳久, 江原 省一, 小林 芳樹, 葭山 稔
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 若年者急性心筋梗塞症の特徴は肥満、および収縮性リモデリングである (2007)
  • Author(s): 江原 省一, 小林 芳樹, 片岡 亨, 白井 伸幸, 山下 啓, 麻植 浩樹, 杉岡 憲一, 穂積 健之, 成子 隆彦, 土師 一夫, 上田 真喜子, 葭山 稔
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 安定狭心症患者におけるPCI前後の酸化ストレスの動態 (2007)
  • Author(s): 白井 伸幸, 江原 省一, 成子 隆彦, 杉岡 憲一, 穂積 健之, 仲川 将志, 北林 千鶴子, 伊倉 義弘, 伊藤 彰, 土師 一夫, 板部 洋之, 葭山 稔, 上田 真喜子
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 頸動脈エコーによるプラーク評価は左冠動脈主幹部のプラークを推定できるか? (2007)
  • Author(s): 片岡 亨, 穂積 健之, 岩田 真一, 竹下 宏明, 小川 景太郎, 西岡 弘樹, 杉岡 憲一, 江原 省一, 小林 芳樹, 吉川 純一, 葭山 稔
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] メタボリックシンドロームの冠動脈の動脈硬化に及ぼす影響について (2007)
  • Author(s): 津森 たから, 片岡 亨, 竹下 宏明, 石井 英, 白井 伸幸, 松本 亮, 中田 真司, 山下 啓, 江原 省一, 小林 芳樹, 葭山 稔
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 急性心筋梗塞症における入院時の血漿中酸化LDL値と再灌流後の微小循環障害 (2007)
  • Author(s): 柚木 佳, 成子 隆彦, 伊藤 彰, 古川 敦子, 田川 慈子, 柳下 大悟, 白井 直哉, 阿部 幸雄, 中川 英一郎, 小松 龍士, 土師 一夫, 白井 伸幸, 江原 省一, 葭山 稔, 仲川 将志, 北林 千津子, 伊倉 義弘, 上田 真喜子
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 末梢血管疾患を合併した冠動脈疾患患者の長期予後 (2007)
  • Author(s): 中田 真司, 横井 良明, 葭山 稔
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 大動脈stiffnessは冠動脈疾患重症度と相関するか?64列マルチスライスCTによる新しい大動脈評価法を用いた検討 (2007)
  • Author(s): 奥山 卓大, 江原 省一, 杉岡 憲一, 麻植 浩樹, 小林 芳樹, 片岡 亨, 山下 啓, 白井 伸幸, 石井 英, 穂積 健之, 上田 真喜子, 葭山 稔
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 不安定狭心症における血漿中ミエロパーオキシダーゼ(MPO)値と冠動脈造影所見との対比 (2007)
  • Author(s): 古川 敦子, 成子 隆彦, 伊藤 彰, 田川 慈子, 柳下 大悟, 柚木 佳, 白井 直哉, 阿部 幸雄, 中川 英一郎 小松 龍士, 土師 一夫, 白井 伸幸, 江原 省一, 葭山 稔, 仲川 将志, 北林 千津子, 伊倉 義弘, 上田 真喜子
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 急性心筋梗塞と酸化-抗酸化バランス血中の酸化LDL値とパラオキソナーゼ蛋白濃度 (2007)
  • Author(s): 江原 省一, 成子 隆彦, 白井 伸幸, 杉岡 憲一, 穂積 健之, 仲川 将志, 北林 千津子, 伊倉 義弘, 伊藤 彰, 土師 一夫, 板部 洋之, 葭山 稔, 上田 真喜子
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ヒト頸動脈のプラーク不安定性血小板盈栓とプラーク修復 (2007)
  • Author(s): 北林 千津子, 江原 省一, 成子 隆彦, 仲川 将志, 白井 伸幸, 杉岡 憲一, 穂積 健之, 葭山 稔, 土師 一夫, 伊倉 義弘, 上田 真喜子
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ヒト冠動脈での薬剤溶出性ステント(DES)留置後の新生内膜形成と血栓形成 (2007)
  • Author(s): 仲川 将志, 江原 省一, 成子 隆彦, 北林 千津子, 伊倉 義弘, 白井 伸幸, 葭山 稔, 伊藤 彰, 土師 一夫, 上田 真喜
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Cypher stent留置後のFFRと慢性期再狭窄の検討 (2007)
  • Author(s): 石井 英, 片岡 亨, 嶋田 芳久, 津森 たから, 竹下 宏明, 白井 伸幸, 松本 亮, 中田 真司, 山下 啓, 江原 省一, 小林 芳樹, 葭山 稔
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Mモード法とストレインエコー法による頸動脈伸展性の比較検討 (2007)
  • Author(s): 前田 久美子, 島田 健永, 福田 祥大, 川崎 俊博, 砂田 寛恵, 田中 秀昌, 實正 哲, 吉田 健, 吉川 純一, 葭山 稔
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 冠血流予備能を用いた主要三冠動脈の再狭窄評価経胸壁心エコードプラ法による検討 (2007)
  • Author(s): 喜多 領一, 兵頭 永一, 平田 久美子, 広瀬 真, 紙森 公雄, 西田 幸生, 瓦林 孝彦, 葭山 稔
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ドブタミン負荷心エコー法におけるストレインを用いた冠動脈狭窄評価Post-systolic shorteningを用いた検討 (2007)
  • Author(s): 兵頭 永一, 平田 久美子, 斎藤 聡男, 広瀬 真, 紙森 公雄, 西田 幸生, 瓦林 孝彦, 葭山 稔
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 拡張型心筋症におけるカルベジロール投与による冠血流予備能改善と遠隔期の左室収縮能改善との関係 (2007)
  • Author(s): 杉岡 憲一, 穂積 健之, 竹本 恭彦, 江原 省一, 小川 景太郎, 岩田 真一, 麻植 浩樹, 松村 嘉起, 大塚 亮, 芳谷 英俊, 吉川 純一, 葭山 稔
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ドブタミン負荷心エコー法における左室アシンクロニー評価の有用性冠動脈疾患患者における検討 (2007)
  • Author(s): 齋藤 聡男, 兵頭 永一, 平田 久美子, 紙森 公雄, 広瀬 真, 瓦林 孝彦, 葭山 稔
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Peripheral artery diseaseに対する診断と治療戦略末梢血管におけるプラーク破裂の頻度と臨床的意義 (2007)
  • Author(s): 大倉 宏之, 田口 晴之, 戸田 為久, 吉田 清, 葭山 稔, 吉川 純一
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] mprovement in Coronary Flow Reserveis Associated With Late Recovery of Left Ventricular Function After Carvedilol Therapy in Patients With Idiopathic Dilated Cardiomyopathy (2007)
  • Author(s): Kenichi Sugioka, MD; Takeshi Hozumi, MD; Yasuhiko Takemoto, MD; Shoichi Ehara, MD; Keitaro Ogawa, MD; Shinichi Iwata, MD; Hiroki Oe, MD; Yoshiki Matsumura, MD; Ryo Otsuka, MD; Hideyuki Yoshitani, MD; Junichi Yoshikawa, MD; Minoru Yoshiyama, MD
  • Organizer: AHA 2007
  • Place of Presentation: 米国、オーランド
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Assessment of Daily Fluctuations in 12-Lead Electrocardiogram and Signal Averaged Electrocardiogram at Risk for Life-threatening Arrhythmic Eventsin Brugada Syndrome (2007)
  • Author(s): Atsushi Doi, Masahiko Takagi, Keiko Maeda, Hiroaki Tatsumi, Eiichiro Nakagawa, Hajime Yamashita, Minoru Yoshiyama
  • Organizer: AHA 2007
  • Place of Presentation: 米国、オーランド
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Comparative Diagnostic Accuracy Between Tri-plane and full volume Three-Dimensional Dobutamine Stress Echocardiography for Detecting Coronary Artery Disease (2007)
  • Author(s): Yoshitani Hidetoshi, Masaaki Takeuchi^*, Takeshi Hozumi, Kenichi Sugioka, Ryo Otsuka, Yasuhiro Takagi, Hiroki Oe, Keitaro Ogawa, Shinichi Iwata, Yasuhiko Takemoto, Minoru Yoshiyama
  • Organizer: AHA 2007
  • Place of Presentation: 米国、オーランド
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 大動脈stiffilessは冠動脈疾患重症度と相関するか?64列マルチスライスCTによる新しい大動脈評価法を用いた検討 (2007)
  • Author(s): 奥山 卓大, 江原 省一, 杉岡 憲一, 麻植 浩樹, 小林 芳樹, 片岡 亨, 山下 啓, 白井 伸幸, 石井 英, 穂積 健之, 上田 真喜子, 葭山 稔
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
• [Presentation] ヒト頸動脈のプラーク不安定性血小板壷栓とプラーク修復 (2007)
  • Author(s): 北林 千津子, 江原 省一, 成子 隆彦, 仲川 将志, 白井 伸幸, 杉岡 憲一, 穂積 健之, 葭山 稔, 土師 一夫, 伊倉 義弘, 上田 真喜子
  • Organizer: 第55回日本心臓病学会・学術集会
  • Place of Presentation: シェラトン・グランデ・トーキョーベイホテル
• [Presentation] mprovement in Coronary Flow Reserve is Associated With Late Recovery of Left Ventricular Function After Carvedilol Therapy in Patients With Idiopathic Dilated Cardiomyopathy (2007)
  • Author(s): Kenichi Sugioka, MD;Takeshi Hozumi, MD;Yasuhiko Takemoto, MD;Shoichi Ehara, MD;Keitaro Ogawa, MD;Shinichi Iwata, MD;Hiroki Oe, MD;Yoshiki Matsumura, MD;Ryo Otsuka, MD;Hideyuki Yoshitani, MD;Junichi Yoshikawa, MD;Miloru Yoshiyama, MD
  • Organizer: AHA2007
  • Place of Presentation: 米国、オーランド
• [Presentation] Assessment of Daily Fluctuations in 12-Lead Electrocardiogram and Signal Averaged Electrocardiogram at Risk for Life-threatening Arrhythmic EventS in Brugada Syndrome (2007)
  • Author(s): Atsushi Doi, Masahiko Takagi, Keiko Maeda, Hiroaki Tatsumi, Eiichiro Nakagaw4 Hajime Yamashita, Minoru Yoshiyama
  • Organizer: AHA2007
  • Place of Presentation: 米国、オーランド
• [Presentation] Comparative Diagnostic Accuracy Between Tri-plane and full volume Three-Dimensional Dobutamine Stress Echocardiography for Detecting Coronary Artery Disease (2007)
  • Author(s): Yoshitani Hidetoshi, Masaaki Takeuchi*, Takeshi Hozumi, Kenichi Sugioka Ryo Otsuka, Yasuhiro Takagi, Hiroki Oe, Keitaro Ogawa, Shinichi Iwata, Yasuhiko Takemoto, Minoru Yoshiyama
  • Organizer: AHA2007
  • Place of Presentation: 米国、オーランド
• [Book] Nippon Rinsho (2007)
  • Author(s): Takemoto Y, Yoshiyama M
  • Total Pages: 5
  • Publisher: 日本臨床社
  • Description: 「研究成果報告書概要(和文)」より
• [Book] Nippon Rinsho (2007)
  • Author(s): Ogawa K, Sugioka K, Yoshiyama M
  • Total Pages: 6
  • Publisher: 日本臨床社
  • Description: 「研究成果報告書概要(和文)」より
• [Book] Clin Calcium (2007)
  • Author(s): Ehara S, Yoshiyama M
  • Total Pages: 12
  • Publisher: 医薬ジャーナル社
  • Description: 「研究成果報告書概要(和文)」より
• [Book] Nippon Rinsho (2007)
  • Author(s): Takemoto Y, Yoshiyama M.
  • Total Pages: 5
• [Book] Nippon Rinsho (2007)
  • Author(s): Ogawa K, Sugioka K, Yoshiyama M.
  • Total Pages: 6
• [Book] Clin Calcium (2007)
  • Author(s): Ehara S, Yoshiyama M.
  • Total Pages: 12