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EFFECTS OF ALL-TRANS RETINOIC ACID AND RETINOIDS ON ANGIOGENESIS

Research Project

Project/Area Number 18591015
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Endocrinology
Research InstitutionTohoku University

Principal Investigator

SUGAWARA Akira  Tohoku University, TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE, PROFESSOR (90270834)

Co-Investigator(Kenkyū-buntansha) ITO Sadayoshi  TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE, 大学院・医学系研究科, PROFESSOR (40271613)
SATO Yasufumi  TOHOKU UNIVERSITY INSTITUTE OF DEVELOPMENT, AGING AND CANCER, PROFESSOR (50178779)
KAGECHIKA Hiroyuki  TOKYO MEDICAL AND DENTAL UNIVERSITY, SCHOOL OF BIOMEDICAL SCIENCE, PROFESSOR (20177348)
SATO Akira  TOHOKU UNIVERSITY, GRADUATE SCHOOL OF MEDICINE, LECTURER (20250764)
宇留野 晃  東北大学, 病院・医員 (90396474)
Project Period (FY) 2006 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥3,790,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥390,000)
Fiscal Year 2007: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2006: ¥2,100,000 (Direct Cost: ¥2,100,000)
Keywordsall-trans retinoic acid / retinoic acid receptor / angiogenesis / retinoid / endothelial cells / all-trans retinoic acid / retinoic acid receptor / angiogenesis / retinoid / endothelial cells / 血管内皮増殖因子 / 動脈硬化 / 受容体
Research Abstract

A natural retinoid all-trans retinoic acid (ATRA) regulates a variety of important cellular functions via retinoic acid receptor (RAR). ATRA has therapeutically been utilized against various malignancies including acute promyelocytic leukemia. Recently, ATRA has also been recognized to be beneficial against atherosclerotic vascular disorders. However, its effects on angiogenesis remain controversial. We therefore examined ATRA effects on in vitro angiogenesis in terms of capillary-like tube formation using human umbilical vein endothelial cells (HUVEC)/normal human dermal fibroblasts (NHDF) co-culture. ATRA as well as RAR agonist Am80 significantly induced capillary-like tube formation. The ATRA-induced tube formation was inhibited by co-incubation with RAR antagonist LE540/LE135. HUVEC proliferation, but not its migration, was also induced by ATRA. The ATRA-induced tube formation was completely abolished by co-incubation with vascular endothelial growth factor (VEGF) neutralizing antibody or with VEGF receptor (VEGFR)-2 (KDR) neutralizing antibody, but not with VEGFR-1 (Flt-1) neutralizing antibody. ATRA and Am80 induced VEGF gene promoter in NHDF was stimulated by ATRA, which was augmented by RAR overexpression. ATRA also induced VDGFR-2/KDR mRNA expression in HUVEC. Moreover, ATRA induced secretion of hepatocyte growth factor (HGF) as well as angiopoietin-2 (Ang-2) in the co-culture. Taken together, ATRA may have induced angiogenesis via RAR mainly by stimulation of HUVEC proliferation and enhancement of endogenous VEGF signaling, and in part by induction of HGF and Ang-2 production. Retinoids may therefore be potential candiadates for therapeutic angiogenesis against ischemic vascular disorders.

Report

(3 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • Research Products

    (170 results)

All 2008 2007 2006 Other

All Journal Article (63 results) (of which Peer Reviewed: 19 results) Presentation (104 results) Book (1 results) Remarks (2 results)

  • [Journal Article] 東北大学医学部附属病院第二内科を受診したクッシング病・クッシング症候群の解析(第三報)2008

    • Author(s)
      菅原 明、伊藤貞嘉
    • Journal Title

      厚生労働科学研究費補助金(難治性疾患克服研究事業)間脳下垂体機能障害調査研究班 総括・分担研究報告書 平成19年度

      Pages: 92-98

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Analyses of Cushing''s syndrome patients who admitted to Tohoku University Hospital2008

    • Author(s)
      Sugawara A, Ito S.
    • Journal Title

      Grants-in-Aid from the Ministry of Health, Labor, and Wetfaxe of Japan Report H19

      Pages: 92-98

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] All-trans retinoic acid induces in vitro angiogenesis via retinoic acid receptor: possible involvement of endogenous vascular endothelial growth factor signaling.2007

    • Author(s)
      Saito A, Sugawara A, Uruno A, Kudo M, Kagechika H, Sato Y, Owada Y, Kondo H, Sato M, Kurabayashi M, Imaizumi M, Tsuchiya S, Ito S
    • Journal Title

      Endocrinology 148

      Pages: 1412-1423

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Agitated depression successfully treated with electroconvulsive therapy combined with steroid cover in apatient with Addison's disease.2007

    • Author(s)
      Suzuki K, Awata S, Oyama Y, Fujiyama M, Takano T, Sugawara A, Matsuoka H
    • Journal Title

      Prog Neuropsychopharmacol Biol Psychiatry 31

      Pages: 956-958

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Induction of PPAR gamma mRNA and protein expression by rosiglitazone in chronic cyclosporine nephropathy in the rat.2007

    • Author(s)
      Ahn KO, Lim SW, Yang HJ, LiC, Sugawara A, Ito S, Choi BS, Kim YS, Kim J, Yang CW.
    • Journal Title

      Yonsei Med J. 48

      Pages: 308-316

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Prognostic significance of vitamin D receptor and retinoid X receptor expression in renal cell carcinoma.2007

    • Author(s)
      Obara W, Konda R, Akasaka S, Nakamura S, Sugawaza A, Fujioka T.
    • Journal Title

      J Urol. 178

      Pages: 1497-1503

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] ストレスとしてのホルモン疾患と心疾患。2007

    • Author(s)
      菅原 明、伊藤貞嘉
    • Journal Title

      CARDIAC PRACTICE 18

      Pages: 37-39

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] となりの総合診療部「東北大学病院総合診療部」2007

    • Author(s)
      菅原 明、金塚 完、長崎 裕、本郷道夫
    • Journal Title

      JIM 17

      Pages: 442-443

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Journal Article] ピタバスタチンが唯一良好な忍容性を示した二次性高脂血症の一例2007

    • Author(s)
      菅原 明、伊藤貞嘉
    • Journal Title

      ホルモンと臨床 55

      Pages: 115-118

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Retinoblastoma interacting zinc finger proteinによるラットヘムオキシゲナーゼ_1遺伝子の転写調節2007

    • Author(s)
      宇留野晃、菅原 明、工藤正孝、伊藤貞嘉
    • Journal Title

      診療と新薬 44

      Pages: 361-366

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 核内受容体PPAR-γ2の脂肪前駆細胞におけるコレステロール欠乏誘導性の発現亢進2007

    • Author(s)
      工藤正孝、菅原 明、宇留野晃、伊藤貞嘉
    • Journal Title

      診療と新薬 44

      Pages: 367-369

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 平成18年度日本内分泌学会研究奨励賞(内科)ホルモン核内受容体の活性化を介した脈管系調節機構の解明2007

    • Author(s)
      菅原 明
    • Journal Title

      東北医学雑誌 119

      Pages: 56-58

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Journal Article] ホルモン核内受容体-PPARγおよびレチノイン酸受容体-の活性化を用いた新しい抗動脈硬化療法の開発2007

    • Author(s)
      菅原 明、宇留野晃、工藤正孝
    • Journal Title

      財団法人中冨健康科学振興財団第18回研究助成業績集 平成19年版

      Pages: 63-65

    • NAID

      10027299733

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Journal Article] 東北大学医学部附属病院第二内科を1996年から2000年にかけて受診したクッシング病およびクッシング症候群の解析2007

    • Author(s)
      菅原 明、伊藤貞嘉
    • Journal Title

      ACTH related peptides 18

      Pages: 35-37

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] All-trans retinoic acid induces in vitro angiogenesis via retinoic acid receptor: possible involvement of endogenous vascular endothelial growth factor signaling2007

    • Author(s)
      Saito A, Sugawara A, Uruno A, Kudo M, Kagechika H, Sato Y, Owada Y, Kondo H, Sato M, Kurabayashi M, Imaizumi M, Tsuchiya S, Ito S.
    • Journal Title

      Endocrinology 148

      Pages: 1412-1423

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Agitated depression successfully treated with electroconvulsive therapy combined with steroid cover in a patient with Addison''s disease2007

    • Author(s)
      Suzuki K, Awata S, Oyama Y. Fujiyama M, Takano T, Sugawara A, Matsuoka H.
    • Journal Title

      ProgNeuTopsychopharmacolBiolPsychiatry 31

      Pages: 956-958

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Induction of PPAR gamma mRNA and protein expression by rosiglitazone in chronic cyclosporine nephropathy in the rat2007

    • Author(s)
      Ahn KO, Lim SW, Yang HJ, Li C, Sugawara A, Ito S, Choi BS, Kim YS, Kim J, Yang CW.
    • Journal Title

      YonseiMedJ 48

      Pages: 308-316

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Prognostic significance of vitamin D receptor and retinoid X receptor expressionin renal cell carcinoma2007

    • Author(s)
      Obara W, Konda R, Akasaka S, Nakamura S, Sugawara A, Fujioka T.
    • Journal Title

      JUroL 178

      Pages: 1497-1503

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effects of stress on hormonal and cardiac disorders2007

    • Author(s)
      Sugawara A, Ito S.
    • Journal Title

      Cardiac Practice 18

      Pages: 37-39

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Tohoku Univ. Hosp. Dept.of Comp. Med2007

    • Author(s)
      Sugawara A, Kanatsuka H, Nagasaki Y, Hongo M.
    • Journal Title

      JIM 17

      Pages: 442-443

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] A case of 2ndry dyslipidemia responded well to oitavastatin2007

    • Author(s)
      Sugawara A, Ito S.
    • Journal Title

      Horumon toRinsyo 55

      Pages: 115-118

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Transcriptional regulation of rat gene by retinoblastoma interacting zinc finger protein2007

    • Author(s)
      Uruno A, Sugawara A, Kudo M, Ito S.
    • Journal Title

      Shinryo to SMayaiu 44

      Pages: 361-366

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] PPARy2 induction by sterol depletion in preadipocytes2007

    • Author(s)
      Kudo M, Sugawara A, Uruno A, Ito S.
    • Journal Title

      Shinryo to Shinyaku 44

      Pages: 367-369

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Functional significance of nuclear receptors in cardiovascular HisnrHprs2007

    • Author(s)
      Sugawara A.
    • Journal Title

      Tbhoku Igakkai Zassi 119

      Pages: 56-58

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effects of PPARv and EAR on atherosclerosis2007

    • Author(s)
      Sugawara A, Uruno A, Kudo M.
    • Journal Title

      Nakatomi Foundation 18^<th> H19

      Pages: 63-65

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Analyses of Cushing''s syndrome patients who admitted to Tohoku University Hospital from 1996 to 20002007

    • Author(s)
      Sugawara A, Ito S.
    • Journal Title

      ACTH related peptides 18

      Pages: 35-37

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Hormones and related materials, adipose tissue2007

    • Author(s)
      Sugawara A.
    • Journal Title

      Simple Biochemistry 5

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Induction of PPAR gamma mRNA and protein expression by rosiglitazone in chronic cyclosporine nephropathy in the rat.2007

    • Author(s)
      Ahn KO, Lim SW, Yang HJ, Li C, Sugawara A, Ito S, Choi BS, Kim YS, Kim J, Yang CW.
    • Journal Title

      Yonsei Med J. 48

      Pages: 308-316

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic significance of vitamin D receptor and retinoid X receptor expression in renal cell carcinoma.2007

    • Author(s)
      Obara W, Konda R, Akasaka S, Nakamura S, Sugawara A, Fujioka T.
    • Journal Title

      J Urol. 178

      Pages: 1497-1503

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Retinoblastoma interacting zinc finger proteinによるラットヘムオキシゲナーゼ-1遺伝子の転写調節2007

    • Author(s)
      宇留野晃、菅原 明、工藤正孝、伊藤貞嘉
    • Journal Title

      診療と新薬 44

      Pages: 361-366

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Agitated depression successfully treated with electroconvulsive therapy combined with steroid cover in a patient with Addison's disease.2007

    • Author(s)
      Suzuki K, Awata S, Oyama Y, Fujiyama M, Takano T, Sugawara A, Matsuoka H
    • Journal Title

      Prog Neuropsychopharmacol Biol Psychiatry Jan 19(Epub ahead of print)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] All-trans retinoic acid induces in vitro angiogenesis viaretinoic acid receptor : possible involvement of endogenous vascular endothelial growth factor signaling.2007

    • Author(s)
      Saito A, Sugawara A, Uruno A, Kudo M, Kagechika H, Sato Y, Owada Y, Kondo H, Sato M, Kurabayashi M, Imaizumi M, Tsuchiya S, Ito S
    • Journal Title

      Endocrinology 148

      Pages: 1412-1423

    • Related Report
      2006 Annual Research Report
  • [Journal Article] ストレスとしてのホルモン疾患と心疾患。2007

    • Author(s)
      菅原 明, 伊藤貞嘉
    • Journal Title

      CARDIAC PRACTICE 18

      Pages: 37-39

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Accelerated diabetic nephropathy in mice lacking the peroxisomeproliferator-activated receptor {alpha}.2006

    • Author(s)
      Park CW, Kim HW, Ko SH, Chung HW, Lim SW. Yang CW, Chang YS, Sugawara A, Guan Y, Breyer MD
    • Journal Title

      Diabetes 55

      Pages: 885-893

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Peroxisome proliferator-activated receptor γ (PPAR γ) in human breast carcinoma: a possible modulator of estrogenic actions.2006

    • Author(s)
      Suzuki T, Hayashi S, Miki Y, Ono K, Nakamura Y, Moriya T, Sugawara A, Ishida T, Ohuchi N, Sasano H
    • Journal Title

      Endocr Relat Cancer 13

      Pages: 233-250

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Assisting the diagnosis of thyroid disease with a neural network making use of routine test data: identification of highly suspected patients with hyperthyroidism.2006

    • Author(s)
      Hoshi K, Kawakami J, Sato W, Sato K, Sugawara A, Saito Y, Yoshida K
    • Journal Title

      Chem Pharm Bull 54

      Pages: 1162-1169

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 全トランス型レチノイン酸および合成レチノイドAm80の血管内皮細胞における遺伝子発現に及ぼす影響-マイクロアレイを用いた検討-。2006

    • Author(s)
      菅原 明、斉藤明子、宇留野晃、今泉益栄、工藤正孝、影近弘之、本郷道夫、伊藤貞嘉
    • Journal Title

      血圧 13

      Pages: 250-252

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 血管新生促進作用。2006

    • Author(s)
      菅原 明、伊藤貞嘉
    • Journal Title

      日本臨床 高血圧(上) 64増刊号

      Pages: 67-69

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] 抗動脈硬化作用を有する心血管作動物質としてのレチノイン酸:その血管内皮機能および血管新生に及ぼす影響の検討。2006

    • Author(s)
      菅原 明、宇留野晃、斉藤明子、工藤正孝、伊藤貞嘉
    • Journal Title

      脈管学 46

      Pages: 365-368

    • NAID

      10018260717

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] グレリンの血管内皮細胞における遺伝子発現に及ぼす影響-マイクロアレイを用いた解析-。2006

    • Author(s)
      菅原 明、斉藤明子、宇留野晃、工藤正孝、伊藤貞嘉
    • Journal Title

      厚生労働科学研究費補助金(難治性疾患克服研究事業)間脳下垂体機能障害調査研究班 総括・分担研究報告書 平成17年度

      Pages: 88-95

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 平成17年度医学部奨学賞金賞 ホルモン核内受容体の活性化を介した脈管系調節機構の解明。2006

    • Author(s)
      菅原 明
    • Journal Title

      東北医学雑誌 118

      Pages: 29-32

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary 2006 Annual Research Report
  • [Journal Article] 糖尿病を有しない低機能性副腎皮質腺腫患者におけるインスリン分泌能・抵抗性の動態。2006

    • Author(s)
      菅原 明、伊藤貞嘉
    • Journal Title

      ACTH related peptides 17

      Pages: 85-88

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] RAA系抑制の意義および展望。2006

    • Author(s)
      菅原 明
    • Journal Title

      登米市医師会だより 365

      Pages: 1-2

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary 2006 Annual Research Report
  • [Journal Article] 平成17年度中冨健康科学振興財団研究助成金ホルモン核内受容体-PPARγおよびレチノイン酸受容体-の活性化を用いた新しい抗動脈硬化療法の開発。2006

    • Author(s)
      菅原 明
    • Journal Title

      東北医学雑誌 118

      Pages: 77-78

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Accelerated diabetic nephropathy in mice lacking the peroxisome proliferatoractivated receptor {alpha}2006

    • Author(s)
      Park CW, Kim HW, Ko SH, Chung HW, Lim SW, Yang CW, Chang YS, Sugawara A, Guan Y, Breyer MD.
    • Journal Title

      Diabetes 55

      Pages: 885-893

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Peroxisome proliferator- activated receptor 7 (PPARr) in human breast carcinoma: a possible modulator of estrogenic nptinns2006

    • Author(s)
      Suzuki T, Hayashi S, Miki Y, Ono K, Nakamura Y, Moriya T, Sugawara A, Ishida T, Ohuchi N, Sasano H.
    • Journal Title

      EndocrRelat Cancer 13

      Pages: 233-250

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Assisting the diagnosis of thyroid diseases with Bayesian-type and SOM-type neural networks making use of routine test data2006

    • Author(s)
      Hoshi K, Kawakami J, Sato W, Sato K, Sugawara A, Saito Y, Yoshida K.
    • Journal Title

      Chem Pharm BuR 54

      Pages: 1162-1169

    • NAID

      110004847236

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effects of ATRA and synthetic retinoid Am80 on endothelial gene expression-DNA microarray analyses2006

    • Author(s)
      Sugawara A, Saito A, Uruno A, Imaizumi M, Kudo M, Kagechika H, Hongo M, Ito S.
    • Journal Title

      Ketsuatsu 13

      Pages: 250-252

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Angiogenesis2006

    • Author(s)
      Sugawara A, Ito S.
    • Journal Title

      Nihonriasyo 64

      Pages: 67-69

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effects of ATRA on endothelial function and angiogenesis2006

    • Author(s)
      Sugawara A, Uruno A, Saito A, Kudo M, Ito S.
    • Journal Title

      Myakkanngaku 46

      Pages: 365-368

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effects of ghrelin on endothelial gene expression-DNA microarray analyses2006

    • Author(s)
      Sugawara A, Saito A, Uruno A, Kudo M, Ito S.
    • Journal Title

      Granta''in-Aidfrom the Ministry of Health, Labor, and Welfare of Japan Report H17

      Pages: 88-95

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effects of nuclear hormone receptors in cardiovascular system2006

    • Author(s)
      Sugawara A.
    • Journal Title

      TohokuIgakkaiZassi 118

      Pages: 29-32

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Insulin secretion/sensitivity in non-functional adrenal adenomas2006

    • Author(s)
      Sugawara A, Ito S.
    • Journal Title

      ACTHrelatedpeptides 17

      Pages: 85-88

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Significance of renirrangiotensin-aldosterone system2006

    • Author(s)
      Sugawara A.
    • Journal Title

      TomesbilahikaiDayori 365

      Pages: 1-2

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effects of PPARy and RAR on atherosclerosis2006

    • Author(s)
      Sugawara A.
    • Journal Title

      TbhokuIgakkaiZassi 118

      Pages: 77-78

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Peroxisome proliferator-activated receptor γ(PPAR γ) in human breast carcinoma : a possible modulator of estrogenic actions.2006

    • Author(s)
      Suzuki T, Hayashi S, Miki Y, Ono K, Nakamura Y, Moriya T, Sugawara A, Ishida T, Ohuchi N, Sasano H
    • Journal Title

      Endocr Relat Cancer 13

      Pages: 233-250

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 抗動脈硬化作用を有する心血管作動物質としてのレチノイン酸 : その血管内皮機能をよび血管新生に及ぼす影響の検討。2006

    • Author(s)
      菅原 明, 宇留野晃, 斉藤明子, 工藤正孝, 伊藤貞嘉
    • Journal Title

      脈管学 46

      Pages: 365-368

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Assisting the diagnosis of thyroid disease with a nenral network making use of routine test data : identification of highly suspected patients with hyperthyroidism.2006

    • Author(s)
      Hoshi K, Kawakami J, Sato W, Sato K, Sugawara A, Saito Y, Yoshida K
    • Journal Title

      Chem Pharm Bull 54

      Pages: 1162-1169

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Accelerated diabetic nephropathy in mice lacking the peroxisome proliferator-activated receptor {alpha}.2006

    • Author(s)
      Park CW, Kim HW, Ko SH, Chung HW, Lim SW, Yang CW, Chang YS, Sugawara A, Guan Y, Breyer MD
    • Journal Title

      Diabetes 55

      Pages: 885-893

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 血管新生促進作用。2006

    • Author(s)
      菅原 明, 伊藤貞嘉
    • Journal Title

      日本臨床 高血圧(上) 64増刊号

      Pages: 67-69

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 全トランス型レチノイン酸および合成レチノイドAm80の血管内皮細胞における遺伝子発現に及ぼす影響-マイクロアレイを用いた検討-。2006

    • Author(s)
      菅原 明, 斉藤明子, 宇留野晃, 今泉益栄, 工藤正孝, 影近弘之, 本郷道夫, 伊藤貞嘉
    • Journal Title

      血圧 13

      Pages: 250-252

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 糖尿病を有しない低機能性副腎皮質腺腫患者におけるインスリン分泌能・抵抗性の動態。2006

    • Author(s)
      菅原 明, 伊藤貞嘉
    • Journal Title

      ACTH related peptides 17

      Pages: 85-88

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 平成17年度中冨健康科学振興財団研究助成金ホルモン核内受容体-PPAR γ およびレチノイン酸受容体-の活性化を用いた新しい抗動脈硬化療法の開発。2006

    • Author(s)
      菅原 明
    • Journal Title

      東北医学雑誌 118

      Pages: 77-78

    • Related Report
      2006 Annual Research Report
  • [Presentation] プロスタサイクリンとNO産生および血管新生2008

    • Author(s)
      菅原 明
    • Organizer
      第3回ASO薬物治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-01-26
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] プロスタサイクリンとNO産生および血管新生2008

    • Author(s)
      菅原 明
    • Organizer
      第3回ASO薬物治療研究会(特別講演)
    • Place of Presentation
      東京
    • Year and Date
      2008-01-26
    • Related Report
      2007 Annual Research Report
  • [Presentation] 東北大学医学部附属病院第二内科を受診したクッシング病・クッシング症候群の解析(第三報)2008

    • Author(s)
      菅原 明、伊藤貞嘉
    • Organizer
      厚生労働省難治性疾患克服研究事業間脳下垂体機能障害調査研究班平成19年度班会議
    • Place of Presentation
      東京
    • Year and Date
      2008-01-11
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] 3rd report of patients with Cushing''s syndrome who Admitted Tohoku Univ. Hosp.2008

    • Author(s)
      Sugawara A, Ito S
    • Organizer
      H19 Meeting of the Ministry of Health, Labor, and Welfare of Japan
    • Place of Presentation
      Tokyo
    • Year and Date
      2008-01-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 糖転移酵素EXTL3の膵β細胞特異的欠損マウスにおけるβ細胞増殖能の低下と耐糖能異常2007

    • Author(s)
      高橋 巌、那谷耕司、野口直哉、池田崇之、吉川雄朗、山内晶世、Nausheen J. Shervani、杉原一司、浅野雅秀、宇留野晃、海野倫明、高澤 伸、岡本 宏、菅原 明
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-13
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Reduced β-cell proliferation and impaired glucose tolerance in pancreatic β-cell specific Extl3 knockout mice2007

    • Author(s)
      Takahashi I, Nata K, Noguchi N, Ikeda T, YoshikawaT, Yamauchi A, Shervani NJ, Sugihara K, Asano M, Uruno A, Unno M, Takasawa S, Okamoto H, Sugawara A
    • Organizer
      80th Annual Meeting of the Japanese Biochemical Society
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-12-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] FK506-binding protein 12.6ノックアウトマウスにおけるブドウ糖刺激インスリン分泌の低下2007

    • Author(s)
      吉川雄朗、野口直哉、池田崇之、高橋 巌、Nausheen J. Shervani、宇留野晃、山内晶世、那谷耕司、高澤 伸、岡本 宏、菅原 明
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-12
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] FK506 disruption impairs glucose-induced insulin secretion2007

    • Author(s)
      Yoshikawa T, Noguchi N, Ikeda T, Takahashi I, Shervani NJ, Uruno A, Yamauchi A, Nata K, Takasawa S, Okamoto H, Sugawara A
    • Organizer
      80th Annual Meeting of the Japanese Biochemical Society
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-12-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 全トランス型レチノイン酸による血管新生促進機構の解明-レチノイン酸受容体及びVEGFシグナルの関与-2007

    • Author(s)
      斉藤明子、菅原 明、宇留野晃、工藤正孝、影近弘之、佐藤靖史、今泉益栄、土屋 滋、伊藤貞嘉
    • Organizer
      日本レチノイド研究会第18回学術集会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-23
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Mechanisms of ATRA-indiced angiogenesis: involvement of VEGF2007

    • Author(s)
      Saito A, Sugawara A, Uruno A, Kudo M, Kagechika H, Sato Y, Imaizumi M, Tsuchiya S, Ito S
    • Organizer
      18th Meeting of Japanese Society for Retinoid Research
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-11-23
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] グレリンの血管内皮細胞における遺伝子発現に及ぼす影響2007

    • Author(s)
      工藤正孝、菅原 明、宇留野晃、斉藤明子、伊藤貞嘉
    • Organizer
      第11回日本心血管内分泌代謝学会総会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-17
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Effects of ghrelin on endothelial gene expression2007

    • Author(s)
      Kudo M, Sugawara A, Uruno A, Saito A, Ito S
    • Organizer
      11th Meeting of the Society of Cardiovascular Endocrinology and Metabolism
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-11-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 外来実習におけるポートフォリオの意義2007

    • Author(s)
      奈良正之, 金塚 完, 長崎 裕, 菅原 明, 本郷道夫
    • Organizer
      第39回日本医学教育学会大会
    • Place of Presentation
      盛岡
    • Year and Date
      2007-07-28
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Significance of Portfolio in outpatient training2007

    • Author(s)
      Nara M, Kanatsuka H, Nagasaki Y, Sugawara A, Hongo M
    • Organizer
      39th Annual Meeting of the Japan Society for Medical Education
    • Place of Presentation
      Morioka
    • Year and Date
      2007-07-28
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 東北大学における地域医療実習の改善と新たな展開2007

    • Author(s)
      金村政輝、菅原 明, 石井誠一, 木村秀樹, 小笠原博信, 溝口二郎, 金塚 完, 伊藤恒敏, 本郷道夫
    • Organizer
      第39回日本医学教育学会大会
    • Place of Presentation
      盛岡
    • Year and Date
      2007-07-27
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Improvement of regional medical training in Tohoku Univ. Sch. of Med.2007

    • Author(s)
      Kanemura M, Sugawara A, ed. al.
    • Organizer
      39th Annual Meeting of the Japan Society for Medical Education
    • Place of Presentation
      Morioka
    • Year and Date
      2007-07-27
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 核内レセプターを標的とした生活習慣病治療:PPRA_Yとレチノイン酸受容体2007

    • Author(s)
      菅原 明、宇留野晃、斉藤明子、Yang Chul Woo、工藤正孝、伊藤貞嘉
    • Organizer
      第80回日本内分泌学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-16
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Functional significance of PPARy and RAR in cardiovascular disorders2007

    • Author(s)
      Sugawara A, Uruno A, Saito A, Yang CW, Kudo M, Ito S
    • Organizer
      80th Japan Endocrine Society Meeting
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-06-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 核内レセプターを標的とした生活習慣病治療:PPRAγとレチノイン酸受容体2007

    • Author(s)
      菅原 明、宇留野晃、斉藤明子、Yang Chul Woo、工藤正孝、伊藤貞嘉
    • Organizer
      第80回日本内分泌学会学術総会(シンポジウム)
    • Place of Presentation
      東京
    • Year and Date
      2007-06-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] フルバスタチンによる管腔形成促進作用はp38 MAPキナーゼに依存する2007

    • Author(s)
      宇留野晃、菅原 明、斉藤明子、工藤正孝、伊藤貞嘉
    • Organizer
      第80回日本内分泌学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-15
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Fluvastatin induces angiogenesis through p38 MAPK2007

    • Author(s)
      Uruno A, Sugawara A, Saito A, Kudo M, Ito S
    • Organizer
      80th Japan Endocrine Society Meeting
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-06-15
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] レチノイン酸とAm80による血管新生促進作用の検討2007

    • Author(s)
      斉藤明子、菅原 明、宇留野晃、工藤正孝、今泉益栄、土屋 滋、伊藤貞嘉
    • Organizer
      第80回日本内分泌学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-14
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Effects of ATRA and Am80 on angiogenesis2007

    • Author(s)
      Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Tuchiya S, Ito S
    • Organizer
      80th Japan Endocrine Society Meeting
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-06-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of prostacyclin on NO production and angiogenesis2007

    • Author(s)
      Sugawara A
    • Organizer
      3rd Meeting of ASO Treatment
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-01-26
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 東北大学医学部附属病院第二内科を受診したクッシング病・クッシング症候群の解析(第二報)。2007

    • Author(s)
      菅原 明、伊藤貞嘉
    • Organizer
      厚生労働省難治性疾患克服研究事業間脳下垂体機能障害調査研究班平成18年度班会議
    • Place of Presentation
      東京
    • Year and Date
      2007-01-12
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 2nd report of patients with Cushing''s syndrome who Admitted Tohoku Univ. Hosp2007

    • Author(s)
      Sugawara A, Ito S
    • Organizer
      H18 Meeting of the Ministry of Health, Labor, and Welfare of Japan
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-01-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Impaired beta-cell replication in heterozygous mutant mice of Reg receptor gene.2007

    • Author(s)
      Takasawa S, Nata K, Takahashi I, Ikeda T, Noguchi N, Yamauchi A, Yoshikawa T, Shervani NJ, Sugihara K, Asano M, Unno M, Sugawara A, Okamoto H
    • Organizer
      American Diabetes Association 67th Scientific Sessions
    • Place of Presentation
      Chicago
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] p38 mitogen-activated protein kinase is involved in up-regulation of angiogenesis in vitro by HMG-CoA reductase inhibitor fluvastatin.2007

    • Author(s)
      Uruno A, Sugawara A, Saito A, Kudo M, Ito S
    • Organizer
      13th World Congress on Heart Disease
    • Place of Presentation
      Vancouver
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Embryonic lethality and impaired beta-cell replication by disruption of Reg receptor gene.2007

    • Author(s)
      Takasawa S, Nata K, Takahashi I, Ikeda T, Noguchi N, Sugihara K, Asano M, Yamauchi A, Yoshikawa T, Shervani NJ, Unno M, Sugawara A, Okamoto H
    • Organizer
      43rd Annual Meeting of the European Association for the Study of Diabetes
    • Place of Presentation
      Amsterdam
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Impaired beta-cell replication in heterozygous mutant mice of Reg receptor gene2007

    • Author(s)
      Takasawa S, Nata K, Takahashi I, Ikeda T, Noguchi N, Yamauchi A, Yoshikawa T, Shervani NJ, Sugihara K, Asano M, Unno M, Sugawara A, Okamoto H
    • Organizer
      American Diabetes Association 67^<th> Scientific Sessions
    • Place of Presentation
      Chicago
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] p38 mitogen-activated protein kinase is involved in up-regulation of angiogenesis in vitro by HMG-CoA reductase inhibitor fluvastatin2007

    • Author(s)
      Uruno A, Sugawara A, Saito A, Kudo M, Ito S
    • Organizer
      13th World Congress on Heart Disease
    • Place of Presentation
      Vancouver
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Embryonic lethality and impaired beta-cell replication by disruption of Reg receptor gene2007

    • Author(s)
      Takasawa S, Nata K, Takahashi I, Ikeda T, Noguchi N, Sugihara K, Asano M, Yamauchi A, Yoshikawa T, Shervani NJ, Unno M, Sugawara A, Okamoto H
    • Organizer
      43rd Annual Meeting of the European Association for the Study of Diabetes
    • Place of Presentation
      Amsterdam
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 気腫性腎盂腎炎に糖尿病性ケトアシドーシス性昏睡を合併した1例。2006

    • Author(s)
      角田宇衣子、檜尾好徳、鈴木 進、菅原 明、山田高弘、平井完史、高橋和眞、荻原健英、片桐秀樹、岡 芳知
    • Organizer
      日本糖尿病学会第44回東北地方会
    • Place of Presentation
      仙台
    • Year and Date
      2006-11-04
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] A case of DKA with pyelonephritis2006

    • Author(s)
      Tsunoda U, Hinikio Y, Suzuki S, Sugawara A, ed. al.
    • Organizer
      44th Regional Meeting of Japan Diabetes Society
    • Place of Presentation
      Sendai
    • Year and Date
      2006-11-04
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 血管内皮細胞の遺伝子発現に及ぼすグレリンの影響-マイクロアレイを用いた検討-。2006

    • Author(s)
      菅原 明、斉藤明子、工藤正孝、宇留野晃、伊藤貞嘉
    • Organizer
      第33回日本神経内分泌学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2006-10-27
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of ghrelin on endothelial gene expression-DNA microarray analyses-2006

    • Author(s)
      Sugawara A, Saito A, Kudo M, Uruno A, Ito S
    • Organizer
      33th Japan Neuroendocrine Society Meeting
    • Place of Presentation
      Yokohama
    • Year and Date
      2006-10-27
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Biphasic effects of fluvastatin on hepatocyte growth factor-induced in vitro angiogenesis and endothelial cell proliferation.2006

    • Author(s)
      Uruno A, Sugawara A, Saito A, Kudo M, Ito S.
    • Organizer
      International Symposium The Kidney and Hypertension.
    • Place of Presentation
      仙台
    • Year and Date
      2006-10-21
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Differential effects of thiazolidinedione, prostacyclin, and statin on gene expression profiles in vascular endothelial cells.2006

    • Author(s)
      Kudo M, Sugawara A, Saito A, Uruno A, Ito S.
    • Organizer
      International Symposium The Kidney and Hypertension.
    • Place of Presentation
      仙台
    • Year and Date
      2006-10-21
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker demonstrate differential gene expression profiles in vascular endothelial cells.2006

    • Author(s)
      Sugawara A, Kudo M, Saito A, Hongo M, Uruno A, Ito S.
    • Organizer
      International Symposium The Kidney and Hypertension.
    • Place of Presentation
      仙台
    • Year and Date
      2006-10-21
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] All-trans retinoic acid induces in vitro angiogenesis possibly via vascular endothelial growth factor signaling.2006

    • Author(s)
      Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Tsuchiya S, Ito S.
    • Organizer
      International Symposium The Kidney and Hypertension.
    • Place of Presentation
      仙台
    • Year and Date
      2006-10-21
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Biphasic effects of fluvastatin on hepatocyte growth factor-induced in vitro angiogenesis and endothelial cell proliferation2006

    • Author(s)
      Uruno A, Sugawara A, Saito A, Kudo M, Ito S
    • Organizer
      International Symposium The Kidney and Hypertension
    • Place of Presentation
      Sendai
    • Year and Date
      2006-10-21
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Differential effects of thiazolidinedione, prostacyclin, and statin on gene expression profiles in vascular endothelial cells2006

    • Author(s)
      Kudo M, Sugawara A, Saito A, Uruno A, Ito S
    • Organizer
      International Symposium The Kidney and Hypertension
    • Place of Presentation
      Sendai
    • Year and Date
      2006-10-21
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker demonstra differential gene expression profiles in vascular endothelial cells2006

    • Author(s)
      Sugawara A, Kudo M, Saito A, Hongo M, Uruno A, Ito S
    • Organizer
      International Symposium The Kidney and Hypertension
    • Place of Presentation
      Sendai
    • Year and Date
      2006-10-21
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] All-trans retinoic acid induces in vitro angiogenesis possibly via vascular endothelial growth factor signaling2006

    • Author(s)
      Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Tsuchiya S, Ito S
    • Organizer
      International Symposium The Kidney and Hypertension
    • Place of Presentation
      Sendai
    • Year and Date
      2006-10-21
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of all-trans retinoic acid on in vitro angiogenesis.2006

    • Author(s)
      Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Tsuchiya S, Ito S.
    • Organizer
      The 21st Scientific Meeting of the International Society of Hypertnesion.
    • Place of Presentation
      福岡
    • Year and Date
      2006-10-19
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of all-trans retinoic acid on in vitro angiogenesis2006

    • Author(s)
      Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Tsuchiya S, Ito S
    • Organizer
      The 21st Scientific Meeting of the International Society of Hypertnesion
    • Place of Presentation
      Fukuoka
    • Year and Date
      2006-10-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of hepatocyte growth factor and fluvastatin co-administration on in vitro angiogenesis and endothelial cell proliferation.2006

    • Author(s)
      Uruno A, Sugawara A, Saito A, Kudo M, Ito S.
    • Organizer
      The 21st Scientific Meeting of the International Society of Hypertnesion.
    • Place of Presentation
      福岡
    • Year and Date
      2006-10-18
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of hepatocyte growth factor and fluvastatin co-administration on in vitro angiogenesis and endothelial cell proliferation2006

    • Author(s)
      Uruno A, Sugawara A, Saito A, Kudo M, Ito S
    • Organizer
      The 21st Scientific Meeting of the International Society of Hypertnesion
    • Place of Presentation
      Fukuoka
    • Year and Date
      2006-10-18
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of pioglitazone, belaprost, and fluvastatin on gene expression in vascular endothelial cells revealed by DNA microarray analyses.2006

    • Author(s)
      Kudo M, Sugawara A, Saito A, Uruno A, Ito S.
    • Organizer
      The 21st Scientific Meeting of the International Society of Hypertnesion.
    • Place of Presentation
      福岡
    • Year and Date
      2006-10-16
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Differential effects of angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker on gene expression in vascular endothelial cells revealed by DNA microarray analyses.2006

    • Author(s)
      Sugawara A, Kudo M, Saito A, Hongo M, Uruno A, Ito S.
    • Organizer
      The 21st Scientific Meeting of the International Society of Hypertnesion.
    • Place of Presentation
      福岡
    • Year and Date
      2006-10-16
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of pioglitazone, belaprost, and fluvastatin on gene expression in vascular endothelial cells revealed by DNA microarray analyses2006

    • Author(s)
      Kudo M, Sugawara A, Saito A, Uruno A, Ito S
    • Organizer
      The 21st Scientifi Meeting of the International Society of Hypertnesion
    • Place of Presentation
      Fukuoka
    • Year and Date
      2006-10-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Differential effects of angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker on gene expression in vascular endothelial cells revealed by DNA microarray analyses2006

    • Author(s)
      Sugawara A, Kudo M, Saito A, Hongo M, Uruno A, Ito S
    • Organizer
      The 21st Scientific Meeting of the International Society of Hypertnesion
    • Place of Presentation
      Fukuoka
    • Year and Date
      2006-10-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 臨床実習における学生-教員間相互評価の導入とフィードバックの効果。2006

    • Author(s)
      石井誠一、本郷道夫、篠澤洋太郎、菅原 明
    • Organizer
      第38回日本医学教育学会大会
    • Place of Presentation
      奈良
    • Year and Date
      2006-07-30
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 医療面接教育実習効果の評価。2006

    • Author(s)
      長崎 裕、菅原 明、金塚 完、本郷道夫
    • Organizer
      第38回日本医学教育学会大会
    • Place of Presentation
      奈良
    • Year and Date
      2006-07-30
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 東北大学医学部における在宅医療実習の現況。2006

    • Author(s)
      菅原 明、金塚 完、長崎 裕、本郷道夫、川島孝一郎、石井誠一
    • Organizer
      第38回日本医学教育学会大会
    • Place of Presentation
      奈良
    • Year and Date
      2006-07-30
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Feedback between teacher and medical students2006

    • Author(s)
      Ishii S, Hongo M, Shinozawa Y, Sugawara A
    • Organizer
      38th Annual Meeting of the Japan Society for Medical Education
    • Place of Presentation
      Nara
    • Year and Date
      2006-07-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Medical interview training2006

    • Author(s)
      Nagasaki Y, Sugawara A, Kanatsuka H, Hongo M
    • Organizer
      38th Annual Meeting of the Japan Society, for Medical Education
    • Place of Presentation
      Nara
    • Year and Date
      2006-07-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Medical training for home care in Tohoku Univ.2006

    • Author(s)
      Sugawara A, Kanatsuka H, Nagasaki Y, Hongo M, Kawashima K, Ishii S
    • Organizer
      38th Annual Meeting of the Japan Society, for Medical Education
    • Place of Presentation
      Nara
    • Year and Date
      2006-07-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 医師の人間性形成に関する医学生の意識調査。第38回日本医学教育学会大会2006

    • Author(s)
      金塚 完、菅原 明、長崎 裕、本郷道夫
    • Organizer
      第38回日本医学教育学会大会
    • Place of Presentation
      奈良
    • Year and Date
      2006-07-29
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 東北大学における地域医療実習の開始とその評価-受入病院と実習学生に対するアンケート調査結果から-。2006

    • Author(s)
      金村政輝、本郷道夫、伊藤恒敏、溝口二郎、石井誠一、菅原 明、木村秀樹
    • Organizer
      第38回日本医学教育学会大会
    • Place of Presentation
      奈良
    • Year and Date
      2006-07-29
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Opinions of medical students2006

    • Author(s)
      Kanatsuka H, Sugawara A, Nagasaki Y, Hongo M
    • Organizer
      38th Annual Meeting of the Japan Society for Medical Education
    • Place of Presentation
      Nara
    • Year and Date
      2006-07-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Regional medical training in Tohoku Univ. Sch. of Med.2006

    • Author(s)
      Kanemura M, Hongo M, Ito T, Mizoguchi J, Ishii S, Sugawara A, Kimura H
    • Organizer
      38th Annual Meeting of the Japan Society for Medical Education
    • Place of Presentation
      Nara
    • Year and Date
      2006-07-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 東北大学病院地域医療連携センターの活動報告。2006

    • Author(s)
      鈴木 栄、國井重男、菅原 明、小丸達也、田熊清継、山内 聡、力山敏樹、青木正志、賀来満夫、中村浩規、西條慶子、金澤悦子、小笠原喜美代、松田みち子、佐々木慶子、五十嵐ひとみ、佐藤裕子、西條久美子、嶺岸恵美、岡本智子、大竹 茜、町田雄一郎、八木巻一男、沖田康雄、斉藤嘉信、渡辺サチ子、日下俊和、山口さやか、盛合沙織、鈴木俊幸、阿部良枝、佐々木巌
    • Organizer
      医療マネジメント学会東北地方会宮城県支部第1回学術総会
    • Place of Presentation
      仙台
    • Year and Date
      2006-07-08
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 東北大学病院の歩み〜取り組みと実績〜。2006

    • Author(s)
      五十嵐ひとみ、西條久美子、大竹 茜、町田雄一郎、渡辺サチ子、青木正志、菅原 明、佐々木巌
    • Organizer
      第四回国立大学医療連携・退院支援部門連絡協議会
    • Place of Presentation
      名古屋
    • Year and Date
      2006-07-08
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Tohoku Univ. Hospital Tiiki Iryou Renkei Center2006

    • Author(s)
      Suzuki S, Kunii S, Sugawara A, ed. al.
    • Organizer
      1st Tohoku Medical Managenment Meeting.
    • Place of Presentation
      Sendai
    • Year and Date
      2006-07-08
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Progress in Tohoku Univ. Hospital.2006

    • Author(s)
      Igarashi H, Saijyou K, Ootake A, Machida Y, Watanabe S, Aoki M, Sugawara A, Sasaki I
    • Organizer
      4th Conference on National Univ. Hospital.
    • Place of Presentation
      Nagoya
    • Year and Date
      2006-07-08
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 肝細胞増殖因子とスタチン製剤の併用による血管新生および細胞増殖能の検討。2006

    • Author(s)
      宇留野晃、菅原 明、斉藤明子、工藤正孝、伊藤貞嘉
    • Organizer
      第49回日本腎臓学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2006-06-16
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of HGF and statin on angiogenesis and cell growth2006

    • Author(s)
      Uruno A, Sugawara A, Saito A, Kudo M, Ito S.
    • Organizer
      49th Annual Meeting of the Japanese Society of Nephrology
    • Place of Presentation
      Tokyo
    • Year and Date
      2006-06-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Prognostic significance of vitamin D receptor and retinoid X-receptors expression in renal cell carcinoma.2006

    • Author(s)
      Obara W, Konda R, Akasaka S, Sugawara A, Fujioka T.
    • Organizer
      The American Urological Association's Annual Meeting.
    • Place of Presentation
      Atlanta
    • Year and Date
      2006-05-21
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] レチノイン酸の血管新生に対する効果。2006

    • Author(s)
      斉藤明子、菅原 明、工藤正孝、宇留野晃、今泉益栄、伊藤貞嘉
    • Organizer
      第12回日本内分泌学会東北地方会
    • Place of Presentation
      仙台
    • Year and Date
      2006-04-08
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of ATRA on angiogenesis2006

    • Author(s)
      Saito A, Sugawara A, Kudo M, Uruno A, Imaizumi M, Ito S
    • Organizer
      12th Tohoku Endocrine Meeting
    • Place of Presentation
      Sendai
    • Year and Date
      2006-04-08
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Peroxisome proliferator-activated receptor γ(PPARγ)in human breast carcinoma: a modulator of estrogenic actions.2006

    • Author(s)
      Suzuki T, Miki Y, Moriya T, Sugawara A, Hayashi S, Sasano H.
    • Organizer
      The Endocrine Society 88th Annual Meeting.
    • Place of Presentation
      Boston
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] PPARαγデュアルリガンドによる血管新生の制御。2006

    • Author(s)
      佐藤眞友美、清水本武、宮地弘幸、影近弘之、菅原 明
    • Organizer
      第79回日本内分泌学会学術総会
    • Place of Presentation
      神戸
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 乳癌組織における核内受容体peroxisome proliferator-activated receptor(PPAR)γの発現意義2006

    • Author(s)
      鈴木 貴、三木康宏、森谷卓也、石田孝宣、菅原 明、林 慎一、大内憲明、笹野公伸
    • Organizer
      第79回日本内分泌学会学術総会
    • Place of Presentation
      神戸
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ピタバスタチンが有効であった下垂体機能低下症に伴う二次性高脂血症の2例。2006

    • Author(s)
      菅原 明、本郷道夫、伊藤貞嘉
    • Organizer
      第79回日本内分泌学会学術総会
    • Place of Presentation
      神戸
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] グレリンの血管内皮細胞における遺伝子発現に及ぼす影響-マイクロアレイを用いた検討-。2006

    • Author(s)
      菅原 明、斉藤明子、工藤正孝、宇留野晃、本郷道夫、伊藤貞嘉
    • Organizer
      第79回日本内分泌学会学術総会
    • Place of Presentation
      神戸
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 肝細胞増殖因子とスタチン系製剤の併用による血管新生作用の検討。2006

    • Author(s)
      宇留野晃、菅原 明、斉藤明子、工藤正孝、伊藤貞嘉
    • Organizer
      第79回日本内分泌学会学術総会
    • Place of Presentation
      神戸
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] レチノイン酸の血管新生に対する効果。2006

    • Author(s)
      斉藤明子、菅原 明、宇留野晃、工藤正孝、今泉益栄、飯沼一宇、伊藤貞嘉
    • Organizer
      第79回日本内分泌学会学術総会
    • Place of Presentation
      神戸
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ホルモン核内受容体の活性化を介した脈管系調節機構の解明。2006

    • Author(s)
      菅原 明
    • Organizer
      第79回日本内分泌学会学術総会
    • Place of Presentation
      神戸
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 東北大学病院総合診療部を受診した糖尿病患者の解析。2006

    • Author(s)
      菅原 明、五味瑠美子、金塚 完、長崎 裕、小川 晋、檜尾 好徳、鈴木 進、片桐 秀樹、伊藤貞嘉、岡 芳知、本郷道夫
    • Organizer
      第49回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 血管内皮細胞におけるプロスタサイクリンによるeNOSリン酸化機構の解明。2006

    • Author(s)
      工藤正孝、菅原 明、宇留野晃、伊藤貞嘉
    • Organizer
      第6回日本NO学会学術集会
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] プロスタサイクリンの血管新生および血管内皮細胞における遺伝子発現に及ぼす影響の検討。2006

    • Author(s)
      菅原 明、工藤正孝、斉藤明子、宇留野晃、本郷道夫、伊藤貞嘉
    • Organizer
      第6回日本NO学会学術集会
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Proteasome inhibitorによる甲状腺未分化癌細胞のapoptosis誘導作用。2006

    • Author(s)
      滝山由美、青木直子、菅原 明、伊藤公一、羽田勝計
    • Organizer
      第49回日本甲状腺学会
    • Place of Presentation
      高松
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 肝細胞増殖因子とスタチン製剤の併用による血管新生および細胞増殖能の検討。2006

    • Author(s)
      宇留野晃、菅原 明、斉藤明子、工藤正孝、伊藤貞嘉
    • Organizer
      第10回日本心血管内分泌代謝学会
    • Place of Presentation
      福井
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] プロスタサイクリンの血管内皮細胞における遺伝子発現に及ぼす影響-マイクロアレイを用いた検討-。2006

    • Author(s)
      工藤正孝、菅原 明、斉藤明子、宇留野晃、伊藤貞嘉
    • Organizer
      第10回日本心血管内分泌代謝学会
    • Place of Presentation
      福井
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ACE阻害薬およびアンジオテンシンII受容体拮抗薬の血管内皮細胞における遺伝子発現に及ぼす影響-マイクロアレイを用いた検討-。2006

    • Author(s)
      菅原 明、工藤正孝、斉藤明子、宇留野晃、伊藤貞嘉
    • Organizer
      第10回日本心血管内分泌代謝学会
    • Place of Presentation
      福井
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] レチノイン酸による血管新生促進作用の検討。2006

    • Author(s)
      斉藤明子、菅原 明、宇留野晃、工藤正孝、今泉益栄、土屋 滋、伊藤貞嘉
    • Organizer
      第10回日本心血管内分泌代謝学会
    • Place of Presentation
      福井
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] significance of vitamin D receptor and retinoid X-receptors expression in renal cell carcinoma.2006

    • Author(s)
      Obara W, Konda R, Akasaka S, Sugawara A, Fujioka T. Prognostic
    • Organizer
      The American Urological Association''s Annual Meeting.
    • Place of Presentation
      Atlanta
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Peroxisome proliferator-activated receptor γ (PPAR γ) in human breast carcinoma: a modulator of estrogenic actions2006

    • Author(s)
      Suzuki T, Miki Y, Moriya T, Sugawara A, Hayashi S, Sasano H
    • Organizer
      The Endocrine Society 88th Annual Meeting
    • Place of Presentation
      Boston
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Regulation of angiogenesis by PPARay dual ligand2006

    • Author(s)
      Sato M, Shimizu M, Miyaji H, Kagechika H, Sugawara A
    • Organizer
      79th Japan Endocrine Society Meeting
    • Place of Presentation
      Kobe
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Significance of PPARr expression in human breast carcinoma2006

    • Author(s)
      Suzuki T, Miki Y, Moriya T, Ishida T, Sugawara A, Ohuchi N, Sasano H
    • Organizer
      79th Japan Endocrine Society Meeting
    • Place of Presentation
      Kobe
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Two cases of 2ndry dyslipidemia responded well to pitavastatin2006

    • Author(s)
      Sugawara A, Hongo M, Ito S
    • Organizer
      79th Japan Endocrine Society Meeting
    • Place of Presentation
      Kobe
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of ghrelin on endothelial gene expression-DNA microarray analyses-2006

    • Author(s)
      Sugawara A, Saito A, Kudo M, Uruno A, Hongo M, Ito S
    • Organizer
      79th Japan Endocrine Society Meeting
    • Place of Presentation
      Kobe
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of HGF and statin on angiogenesis2006

    • Author(s)
      Uruno A, Sugawara A, Saito A, Kudo M, Ito S
    • Organizer
      79th Japan Endocrine Society Meeting
    • Place of Presentation
      Kobe
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of ATRA on angiogenesis2006

    • Author(s)
      Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Iinuma K, Ito S
    • Organizer
      79th Japan Endocrine Society Meeting.
    • Place of Presentation
      Kobe
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Functional significance of nuclear receptors in cardiovascular disorders2006

    • Author(s)
      Sugawara A
    • Organizer
      79th Japan Endocrine Society Meeting.
    • Place of Presentation
      Kobe
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Analyses of diabetes patients Who admitted to Tohoku Univ. Hosp. Dept. of Comp. Med.2006

    • Author(s)
      Sugawara A, Gomi R, Kanatsuka H, Nagasaki Y, Ogawa S, Hinokio Y, Suzuki S, Katagiri H, Ito S, Oka Y, Hongo M
    • Organizer
      49th Japan Diabetes Society Meeting
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of prostacyclin on eNOS phosphprylation2006

    • Author(s)
      Kudo M, Sugawara A, Uruno A, Ito S
    • Organizer
      6th Annual Scientific Meeting of the NO Society of Japan
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of prostacyclin on angiogenesis and endothelial gene expression2006

    • Author(s)
      Sugawara A, Kudo M, Saito A, Uruno A, Hongo M, Ito S
    • Organizer
      6th Annual Scientific Meeting of the NO Society of Japan
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Induction of apoptisis in thyroid undifferentiated ca. by proteasome inhibitor2006

    • Author(s)
      Takiyama Y, Aoki N, Sugawara A, Ito K, Haneda M
    • Organizer
      49th Japan Thyroid Meeting
    • Place of Presentation
      Takamatsu
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of HGF and statin on angiogenesis and cell growth2006

    • Author(s)
      Uruno A, Sugawara A, Saito A, Kudo M, Ito S
    • Organizer
      10th Meeting of the Society of Cardiovascular Endocrinology and Metabolism
    • Place of Presentation
      Fukui
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of prostacyclin on endothelial gene expression-DNA microarray analyses-2006

    • Author(s)
      Kudo M, Sugawara A, Saito A, Uruno A, Ito S
    • Organizer
      10th Meeting of the Society of Cardiovascular Endocrinology and Metabolism
    • Place of Presentation
      Fukui
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of ACEi and ARB on endothelial gene expression-DNA microarray analyses-2006

    • Author(s)
      Sugawara A, Kudo M, Saito A, Uruno A, Ito S
    • Organizer
      10th Meeting of the Society of Cardiovascular Endocrinology and Metabolism
    • Place of Presentation
      Fukui
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of ATRA on angiogenesis2006

    • Author(s)
      Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Tsuchiya S, Ito S
    • Organizer
      10th Meeting of the Society of Cardiovascular Endocrinology and Metabolism
    • Place of Presentation
      Fukui
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] シンプル生化学(改訂第5版):「ホルモンおよびその関連物質」「脂肪組織」2007

    • Author(s)
      菅原 明
    • Publisher
      南江堂
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Remarks] 「研究成果報告書概要(和文)」より

    • URL

      http://www.med.tohoku.ac.jp/org/contribute/99/index.html

    • Related Report
      2007 Final Research Report Summary
  • [Remarks]

    • URL

      http://www.med.tohoku.ac.jp/room/311/japanese.html

    • Related Report
      2007 Annual Research Report

URL: 

Published: 2006-04-01   Modified: 2016-04-21  

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