| Budget Amount *help |
¥1,450,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2006: ¥800,000 (Direct Cost: ¥800,000)
|
|---|
| Research Abstract |
Maternal smoking is known as one of risk factors of SIDS. The present study was undertaken to evaluate whether maternal smoking impairs arousal process.
Twenty infants were studied polygraphically during one night; ten infants were from smoking mothers, ten infants from non-smoking. Infants were matched for gender, gestational age and age at recording. Arousals were differentiated into subcortical activation or cortical arousals, according to the presence of autonomic and/or EEG changes.
Cortical arousals were more frequent in REM sleep than in NREM sleep (p<0.0001, in both groups). There were no differences in subcortical activations between REM and NREM sleep in both groups. During REM sleep, frequency of cortical arousals was higher than that of subcortical activations (p<0.0001, in both groups). No differences were found in NREM sleep.
Compared with non-smoking group, smoking group showed less frequent cortical arousals and more frequent subcortical activations during REM sleep (frequencies of cortical arousals: smoking; 10.4/h, non-smoking; 14.2/h, frequencies of subcortical activations: smoking; 2.2/h, non-smoking; 1.6/h), but these were not statistically significant. During NREM sleep, there were no significant differences in cortical arousals and subcortical activations between the two groups.
The infants with maternal smoking tend to show more frequent subcortical activations and less cortical arousals compared with the infants without maternal smoking, as previously seen in SIDS victims.
|
