The examinations of mechanisms and prediction of efficacy of rTMS treatment for schizophrenia using neuroimaging techniques of MEG
| Project/Area Number |
18591284
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Wakayama Medical University |
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Principal Investigator |
UKAI Satoshi Wakayama Medical University, 医学部, 准教授 (80324763)
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| Co-Investigator(Kenkyū-buntansha) |
ISHII Ryouhet 大阪大学, 大学院・医学系研究科, 助教 (40372619)
IWASE Masao 大阪大学, 大学院・医学系研究科, 助教 (60362711)
TAKEDA Masatoshi 大阪大学, 大学院・医学系研究科, 教授 (00179649)
SHINOSAKI Kazuhiro 和歌山県立医科大学, 医学部, 教授 (40215984)
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| Project Period (FY) |
2006 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
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| Budget Amount *help |
¥3,800,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2006: ¥2,500,000 (Direct Cost: ¥2,500,000)
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| Keywords | 統合失調症 / 脳磁図 / 反復的経頭蓋磁気刺激 / 語産生課題 / 経頭蓋的磁気刺激 |
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| Research Abstract |
統合失調症の治療には通常薬物療法が選択されるが、今後期待されるその他の治療法のひとつに反復的経頭蓋磁気刺激療法がある。この治療法は幻聴や陰性症状の改善に有効である可能性が指摘されているが、その作用機作は不明であり、個々の症例での有効性の予測の指標も確立されていない。本研究では脳磁図を用いた時間分解能の高い脳機能画像を得る手法を確立するとともに、それを用いて本治療法の作用機作や有効性予測の指標を確立することを最終目標として基礎的な研究をおこない、いくつかの重要な成果を得た。
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Report
(4 results)
Research Products
(113 results)
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[Journal Article] Discrepancy of performance among working memory-related tasks in autism spectrum disorders was caused by task characteristics, apart from working memory, which could interfere with task execution2006
Author(s)
Nakahachi Honaga E, Sekiyama R, Ukai S, Ishii R, Ishigami T, Iwase M, Takahashi H, W, Kajimoto O, Yamashita K, Hashimoto R, Tanii H, Shimizu A, Takeda M
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Journal Title
Psychiatry Clin Neurosci 60
Pages: 312-318
Related Report
Peer Reviewed
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[Journal Article] Right parietal activation during delusional state in episodic interictal psychosis of epilepsy : A report of two cases2006
Author(s)
Ishii R, Canuet L, Iwase M, Kurimoto R, Ikezawa K, Robinson SE, Ukai S, Shinosaki K, Hirata M, Yoshimine T, Takeda M
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Journal Title
Epilepsy Behav 9
Pages: 367-372
Related Report
Peer Reviewed
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[Presentation] Neuromagnetic oscillatory response during movement observation in Asperger disorder2006
Author(s)
Honaga E, Ukai S, Ishii R, Kawaguchi S, Yamamoto M, Ogawa A, Nakahachi T, Fujita N, Yoshimine T, Shinosaki K, Takeda M
Organizer
28th International Congress of Clinical Neurophysiology
Place of Presentation
Edinburgh
Related Report
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[Presentation] SAM(g2) analysis : A new approach for MEG source localization of epilepsy2006
Author(s)
Ishii R, Robinson SE, Iwase M, Canuet L, Kurimoto R, Ikezawa K, Azechi M, Ukai S, Yoshimine T, Shinosaki K, Takeda M
Organizer
14th Biennial Congress of the International Pharmaco-EEG Society (IPEG)
Place of Presentation
Awaji Island
Related Report
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[Book] Slow repetitive transcranial magnetic stimulation changes oscillatory magnetoencephalographic activity in two patients with thalamic pain. In New Frontiers in Biomagnetism(Cheyne D, Ross B, Stroink G, Weinberg H (eds.))2007
Author(s)
Kurimoto R, Ishii R, Canuet L, Iwase M, Sekiyama R, Takahashi K, Nakahachi T, Ukai S, Shinosaki K, Takeda M
Publisher
Elsevier, Amsterdam
Related Report
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[Book] MEG neuroimaging of delusions in episodic interictal psychosis of epilepsy. In New Frontiers in Biomagnetism(Cheyne D, Ross B, Stroink G, Weinberg H (eds.))2007
Author(s)
Ishii R, Canuet L, Iwase M, Kurimoto R, Ikezawa K, Robinson SE, Ukai S, Shinosaki K, Hirata M, Yoshimine T, Takeda M
Publisher
Elsevier, Amsterdam
Related Report
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