| Budget Amount *help |
¥3,950,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2006: ¥2,000,000 (Direct Cost: ¥2,000,000)
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| Research Abstract |
The DC potential at the rat frontal cortex showed a significant diurnal variation, and its negative shifts were accompanied by muscular activation and delta wave suppression, indicating its relationship with arousal level. DC potential shifts were also observed at the frontal cortex on expecting the footshock stress. Acute stress application induced a significant NA increase at the cerebral cortex, hypothalamus and hippocampus 7 days after the footshock stress. These results suggest that stress induces changes in frontal DC potential and noradrenaline activity, leading to generation of hyperarousal state.
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