Analysis of regional brain elasticity using MRI

• Project/Area Number: 18591331
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kanazawa University
• Principal Investigator: MIYATI Tosiaki Kanazawa University, 保健学系, 教授 (80324086)
• Co-Investigator(Kenkyū-buntansha): MASE Mitsuhito 名古屋市立大学, 医学研究科, 准教授 (60238920)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥4,100,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥600,000); Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2007: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2006: ¥1,500,000 (Direct Cost: ¥1,500,000)
• Keywords: 脳・神経 / 脳神経疾患 / 磁気共鳴画像(MRI) / 弾性 / 水分子 / 拡散 / 医療・福祉 / 頭蓋内圧

Research Abstract

磁気共鳴画像から脳局所の弾性を評価する方法を確立し, 非侵襲的に頭蓋内環境の局所変化を伴う病変の診断に役立てることを試みた. 心周期における脳局所の水分子拡散の変化量および頭蓋内容積変化との関係を検討した結果, 心周期における水分子拡散の変化量は, 脳の局所弾性に関与し, 正常圧水頭症の診断に役立つと結論付けた.

Research Products

• [Journal Article] Diffusion tensor magnetic resonance imaging in patients with possible idiopathic normal pressure hydrocephalus before and after tap test (2009)
  • Author(s): Demura K, Mase M, Osawa T, Hattori M, Kasai H, Miyati T, Yamada K
  • Journal Title: Nagoya Medical Journal (in press)
  • NAID: 110008138503
  • Peer Reviewed
• [Journal Article] Noninvasive estimation of intracranial compliance in idiopathic NPH using MRI (2009)
  • Author(s): Mase M, Miyati T, Demura K, Kasai H, Hara M, Shibamoto Y, Yamada K
  • Journal Title: Acta Neurochir Suppl (in press)
• [Journal Article] Bulk motion independent analyses of water diffusion change in the brain during the cardiac cycle (2009)
  • Author(s): Nakamura T, Miyati T, Kasai H, Ohno N, Yamada M, Mase M, Hara M, Shibamoto Y, Suzuki Y, Ichikawa K
  • Journal Title: Radiol Phys Technol (in press)
  • NAID: 120001591944
  • Peer Reviewed
• [Journal Article] Hemodynamic characterization of brain tumor with dual dynamic contrast enhanced magnetic resonance image (2009)
  • Author(s): Hyuga T, Mase M, Miyati T, Yamada K
  • Journal Title: Nagoya Medical Journal (in press)
  • Peer Reviewed
• [Journal Article] Cine MRI による非侵襲的頭蓋内コンプライアンス測定法 : 発性正常圧水頭症での検討 (2009)
  • Author(s): 間瀬光人, 宮地利明, 大沢知士, 出村光一朗, 山田和雄
  • Journal Title: 小児の脳神経 (in press)
• [Journal Article] 心周期における脳局所のΔADC解析 (2009)
  • Author(s): 大野直樹, 宮地利明, 間瀬光人, 笠井治昌, 菅博人, 朝日美幸, 川野誠, 原眞咲, 芝本雄太, 上田優
  • Journal Title: 医用画像情報学会雑誌 26 Pages: 17-20
  • NAID: 130002069146
  • Peer Reviewed
• [Journal Article] 心周期における脳局所のΔADC解析 (2009)
  • Author(s): 大野直樹
  • Journal Title: 医用画像情報学会雑誌 26 Pages: 17-20
  • Peer Reviewed
• [Journal Article] Bulk motion independent analyses of water diffusion change in the brain during the cardiac cycle (2009)
  • Author(s): Tomoya Nakamura
  • Journal Title: Radiol Phys Technol 2(掲載確定)
  • Peer Reviewed
• [Journal Article] Cine MRIによる非侵襲的頭蓋内コンプライアンス測定法 : 特発性正常圧水頭症での検討 (2009)
  • Author(s): 間瀬光人
  • Journal Title: 小児の脳神経 (掲載確定)
  • NAID: 10026413385
• [Journal Article] Noninvasive estimation of intracranial compliance in idiopathic NPH using MRI (2008)
  • Author(s): Mitsuhito Mase
  • Journal Title: Acta Neurochir Suppl 掲載確定
• [Journal Article] Noninvasive MRI assessment of intracranial compliance in idiopathic normal pressure hydrocephalus (2007)
  • Author(s): Miyati T, Mase M, Kasai H, Hara M, Yamada K, Shibamoto Y, Soellinger M, Baltes C, Luechinger R
  • Journal Title: J Magn Reson Imaging 26 Pages: 274-278
  • NAID: 120001138014
  • Peer Reviewed
• [Journal Article] Bulk motion independent analyses of water diffusion change in brain during cardiac cycle (2007)
  • Author(s): Miyati T, Yamada M, Kasai H, Nakamura T, Mase M, Hara M, Yamada K, Shibamoto Y, Suzuki Y, Van Cauteren M
  • Journal Title: Proc. Intl. Soc. Mag. Reson. Med. 15 Pages: 3514-3514
  • NAID: 120001591944
• [Journal Article] Noninvasive MRI assessment of intracianial compliance in idiopathic norural pressure hydrocephalus (2007)
  • Author(s): Tosiaki Miyati
  • Journal Title: J Magn Reran Imaging 26 Pages: 274-278
  • Peer Reviewed
• [Journal Article] Bulk motion independent analyses of water doffusion change in brain during cardiac cycle (2007)
  • Author(s): Tosiaki Miyati
  • Journal Title: Pros.Intl.Soc.Mag.Reson.Med. 15 Pages: 3514-3514
• [Journal Article] Noninvasive MRI assessment of intracranial compliance in idiopathic normal pressure hydrocephalus (2007)
  • Author(s): Toshiaki Miyati
  • Journal Title: J Magn Reson Imaging (in press)
  • NAID: 120001138014
• [Journal Article] MRI-intracranial compliance analysis in patients with NPH (2006)
  • Author(s): Matsunaga S, Miyati T, Mase M, Kasai H, Nakajima H, Mori K, Kawamura F, Sugiyama M, Hara M, Shibamoto Y, Suzuki M
  • Journal Title: Jpn J Radil Technol 62 Pages: 63-69
  • NAID: 110003486088
  • Peer Reviewed
• [Presentation] Regional delta-diffusion analysis of the brain during cardiac cycle in idiopathic normal-pressure hydrocephalus (2009)
  • Author(s): Naoki Ohno
  • Organizer: 21th European Congress of Radiology
  • Place of Presentation: Vienna (Austria)
  • Year and Date: 2009-03-08
• [Presentation] Regional delta-diffusion analysis of the brain during cardiac cycle in idiopathic normal-pressure hydrocephalus (2009)
  • Author(s): Ohno N, Miyati T, Mase M, Kasai H, Hara M, Shibamoto Y, Yamada K, Kawano M, Kan H
  • Organizer: normal-pressure hydrocephalus, 21th European Congress of Radiology (ECR 2009)
  • Place of Presentation: Vienna (Austria)
• [Presentation] MRIによる非侵襲的頭蓋内コンプライアンス測定法 ; 特発性正常圧水頭症での検討 (2008)
  • Author(s): 間瀬光人, 宮地利明, 出村光一朗, 笠井治昌, 山田和雄
  • Organizer: 第67回日本脳神経外科学会学術総会
  • Place of Presentation: 盛岡
  • Year and Date: 2008-10-02
• [Presentation] 心周期における脳局所のΔdiffusion 解析 (2008)
  • Author(s): 大野直樹, 宮地利明, 中村智哉, 笠井治昌, 森俊章, 山田雅人, 上田優
  • Organizer: 日本放射線技術学会64回総会
  • Place of Presentation: 横浜
  • Year and Date: 2008-04-04
• [Presentation] 心周期における脳局所のΔ diffusion解析 (2008)
  • Author(s): 大野直樹
  • Organizer: 日本放射線技術学会64回総会
  • Place of Presentation: 横浜
  • Year and Date: 2008-04-04
• [Presentation] Bulk motion independent analyses of water diffusion change in brain during cardiac cycle (2007)
  • Author(s): Tosiaki Miyati
  • Organizer: ISMRM-ESMRMB 2007
  • Place of Presentation: Berlin (Germany)
  • Year and Date: 2007-05-23
• [Presentation] Noninvasive estimation of intracranial compliance in idiopathic NPH using MRI (2007)
  • Author(s): Mase M, Miyati T, Demura K, Kasai H, Hara M, Shibamoto Y, Yamada K
  • Organizer: 13th International Symposium on Intracranial Pressure and Brain Monitoring
  • Place of Presentation: San Francusco (California)
• [Presentation] Intracranial compliance in idiopathic normal pressure hydrocephalus/noninvasive measurement using MRI (2007)
  • Author(s): Mase M, Miyati T, Demura K, Kasai H, Hara M, Shibamoto Y, Yamada K
  • Organizer: 9th Biannual Meeting of the JAH
  • Place of Presentation: Paris(France)
• [Presentation] Noninvasive estimation of intracranial compliance in idiopathic NPH using MRI (2007)
  • Author(s): Mitsuhito Mase
  • Organizer: 13th International Symposium on Intracranial Pressure and Brain Monitoring
  • Place of Presentation: San Francisco(USA)
• [Presentation] Bulk motion independent analysis of restricted water diffusion change in brain during cardiac cycle (2006)
  • Author(s): Nakamura T, Miyati T, Hara M, Shibamoto Y, Kasai H, Sato S, Yamada M, Ueda Y, Suzuki Y, Hirose Y
  • Organizer: 92nd RSNA Meeting
  • Place of Presentation: Chicago (USA)
  • Year and Date: 2006-11-26
• [Presentation] 突発性正常圧水頭症における頭蓋内コンプライアンスのMRIによる評価 (2006)
  • Author(s): 笠井治昌, 宮地利明, 間瀬光人, 森清孝, 朝日美幸, 松永紗代子, 廣瀬保次郎, 杉山雅之
  • Organizer: 日本放射線技術学会第34回秋季学術大会
  • Place of Presentation: 札幌
  • Year and Date: 2006-10-20
• [Presentation] ECG-triggered diffusion MRI を使用した脳における水分子の動的変化の検討 (2006)
  • Author(s): 中村智哉, 宮地利明, 森俊章, 鈴木由里子, van Cauteren M, 笠井治昌, 川村富士夫
  • Organizer: 日本放射線技術学会第62回総会
  • Place of Presentation: 横浜
  • Year and Date: 2006-04-08